To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Carl Snyder was one of the most prominent US monetary economists of the 1920s and 1930s. His pioneering work on constructing the empirical counterparts of the terms in the equation of exchange led him to formulate a 4% monetary growth rule. Snyder is especially apposite because he was on the staff of the New York Federal Reserve Bank. Why, despite his pioneering empirical work and his position as an insider, did Snyder fail to effectively challenge the dominant real bills views of the Federal Reserve (Fed)? A short answer is that he did not possess a convincing version of the quantity theory that attributed the Great Depression to a contraction in the money stock produced by the Fed, as opposed to the dominant real bills view attributing it to the collapse of speculative excess.
The cause of most CHD is unknown and considered complex, implicating genetic and environmental factors in disease causation. The Kids Heart BioBank was established in 2003 to accelerate genetic investigations into CHD.
Methods:
Recruitment includes patients undergoing interventions for CHD at The Children’s Hospital at Westmead. Informed consent is obtained from parents/guardians, and blood is collected at the time of cardiac intervention from which DNA is extracted and stored. Associated detailed clinical information and a family history are stored in the purpose-designed database.
Results:
To date, the Kids Heart BioBank contains biospecimens and associated clinical information from over 4,900 patients with CHD and their families. Two-thirds (64.1%) of probands have been included in research studies with 28.9% of participants who underwent genomic sequencing receiving a molecular diagnosis with direct clinical utility. The value of this resource to patients and families is highlighted by the high consent rate (94.6%) and the low withdrawal of consent rate (0.4%). The Kids Heart BioBank has supported many large national and international collaborations and contributed significantly to CHD research.
Conclusions:
The Kids Heart BioBank is an invaluable resource and, together with other similar resources, the resulting research has paved the way for clinical genetic testing options for CHD patients, previously not possible. With research in the field moving away from diagnosing monogenic disease, the Kids Heart BioBank is ideally placed to support the next chapter of research efforts into complex disease mechanisms, requiring large patient cohorts with detailed phenotypic information.
This article analyzes how the European Court of Human Rights (ECtHR) handles evidence of pushback, where states violently force asylum seekers away from borders. An examination of how the experiences of pushback survivors get translated (or not) into judgments contributes to theoretical discussions about truth, epistemic practices, and law. The article asks why so little of what researchers, journalists, civil society actors, and international organizations have documented about European border violence is visible in the court’s judgments. Based on a mix of legal and anthropological research methods, the article traces how states and the ECtHR erase pushback evidence at borders and during litigation. Taking seriously on equal grounds the construction of facts outside and inside a court room, the article connects external perspectives on the production of evidence with an internal analysis of evidence in judgments. In doing so, the article highlights the political dimensions of seemingly merely technical and legal procedures. We argue for a clearer separation of courts’ and states’ versions of facts, contending that the presumption of the states’ good faith should no longer apply when there is evidence, including in case law, of misrecordings and false statements by respondent states.
Ludwig von Mises’s methodological apriorism is often attributed to the broader Austrian School of economics. However, there is considerable controversy concerning the meaning of Mises’s justification of his apriorism. There are inconsistencies within and across Mises’s methodological writings that engender confusion in the secondary literature. This confusion is aggravated by the fact that his apriorism cannot be interpreted as an artifact of his historical milieu. The two prevailing families of interpretation both treat Mises’s apriorism as anachronistic, albeit in divergent senses. I conclude that the primary and secondary literatures on Mises’s apriorism indicate its inconsistency and incoherence. We have no idea what justification Mises intended when he asserted the a priori nature of the fundamental propositions of economics. If this is right, then, whatever method(s) they follow, Austrian economists cannot (deliberately) follow Mises’s apriorism, because no one knows well enough how Mises meant to justify it to follow it purposefully.
The global surge in childhood obesity is also evident in Indonesia. Parental body mass index (BMI) values were found to be one of the major determinants of the increasing prevalence of childhood obesity. It is uncertain if parental BMI during their offspring’s childhood significantly affects their children’s BMI trajectories into adulthood. We aimed to investigate the influence of parental BMI Z-scores on BMI trajectories of Indonesian school-aged children, with a focus on sex-specific effects. This study utilized data from the Indonesian Family Life Survey and tracked the same respondents over four time points, from wave 2 (1997–1998) to wave 5 (2014–2015). The sample of this study consisted of children aged 5–12 years in wave 2 for whom height and weight data were available. We utilized a two-level growth curve model to account for the hierarchical structure of the data, with time nested within individual children. Fathers’ BMI Z-scores in wave 2 had a pronounced influence (β = 0.31) on female children’s BMI Z-scores compared to the influence of mothers’ BMI Z-scores (β = 0.17). Mothers’ BMI Z-scores in wave 2 showed a stronger positive association with male children’s BMI Z-scores (β = 0.22) than did the father’s BMI Z-scores (β = 0.19). A significant interaction of fathers’ BMI Z-scores and years of follow-up was found for male children. As male children’s BMI Z-scores increased by year, this effect was stronger in those whose fathers’ BMI Z-scores were at a higher level. In conclusion, we found that parental BMI values profoundly influenced their children’s BMI trajectories.
Global governance institutions have increasingly ‘opened up’ to non-state actors, leading to more formally inclusive governance arrangements. This has prompted inquiry into the extent and the drivers of this inclusivity, patterns of participation, and the consequences for the legitimacy and effectiveness of global governance. However, while the measurement of formal openness has expanded, the quality of inclusion remains underexplored. We therefore introduce a framework centred on the notion of ‘meaningful inclusion’, distinguishing between formal (de jure) structures and the perceived quality of actual (de facto) engagement. Drawing on extensive empirical data, we then examine the Global Partnership for Effective Development Cooperation. This case exemplifies strong formal mechanisms for inclusion that are contrasted sharply by significant shortcomings in effective engagement. Our findings suggest that improvements in formal global governance structures alone cannot ensure meaningful inclusion. Instead, we highlight the centrality of power dynamics and vested interests in shaping inclusivity dynamics in practice.
Abolition of slavery in British colonies led to the facilitation of Indian indentured migration by the British government. This form of migration came about when the discourse of economic freedom and individual liberty strongly resonated in British political economy circles, following the work of Adam Smith and John Stuart Mill. We analyze how unfreedom in indentured labor was rationalized when the rhetoric of freedom was essential to the dominant intellectual milieu. We consider why free labor was deemed unfeasible in the plantation colonies. We also consider the constraints that asymmetric information and unequal bargaining posed to freedom within the institution of indenture. We conclude that indenture represented an uneasy compromise between the problems of slavery and the unattainable goal of free labor.
This article analyzes Turkish foreign policy during the Iranian oil crisis of 1951–1953 and argues that Turkey shaped its policy based on Cold War politics. While Turkey cared less for Iran’s nationalization of oil, it was more concerned about the political implications of the crisis. At the beginning of the crisis, Turkey was focused on guaranteeing its own NATO membership. After joining NATO in 1952, the country assumed a more active role in the crisis. As the coalition behind Premier Dr Mohammad Mosaddegh dissolved, Turkey became more concerned about both the internal situation in Iran and the broader Middle Eastern context following the July 21, 1952 events in Iran and the 1952 Egyptian coup. The strongest opposition to Mosaddegh came from Ayatollah Abul Qassim Kashani who was both an important religious figure and the speaker of the Majlis. Turkey was concerned about Kashani’s politics of a “third bloc” and supported Mosaddegh’s pro-American position. Keeping Mosaddegh in power was in line with Turkey’s general Middle Eastern policy which aimed at forming a Western-oriented regional defense organization. This article will analyze the shaping of Turkish foreign policy towards the Iranian oil crisis within the context of this regional rivalry.
Knowledge of local antibiotic resistance data, provided by antibiograms (a cumulative summary of in vitro-antimicrobial-susceptibility-test results), can aid prescribing of appropriate empirical antibiotics. This study aimed to explore the feasibility of antibiogram development for residential aged care facilities (RACFs).
Design:
Retrospective observational study of culture and sensitivity data.
Setting:
Nine RACFs in Queensland, Australia.
Method:
Available antimicrobial susceptibility results were collected retrospectively for all residents of recruited RACFs from January 1, 2020, to December 31, 2022. Data were managed and analyzed with WHONET software®, and antibiograms were developed in accordance with the CLSI-M39 guidelines. Antibiogram data beyond the standard 12-months and pooling of data from geographically similar RACFs were explored as options to improve feasibility and validity of the antibiograms.
Results:
The most prevalent bacteria in the RACFs were Escherichia coli and Staphylococcus aureus. Due to the low number of positive cultures (less than 30) for individual RACFs, an annual antibiogram was not feasible. Extending the time-period to three years improved feasibility of antibiograms for E.coli in seven RACFs and S.aureus in five RACFs. Combining the data from closely located RACFs allowed for sufficient urinary and skin swab isolates to produce annual pooled antibiograms for all three years.
Conclusion:
Use of extended time period antibiograms can provide RACF specific urinary and skin/soft tissue resistance data without the necessity of private pathology provider input. However, pooled syndromic antibiograms can be made available on an annual basis, which may be the preferred option.
Drop collision with a solid particle is a ubiquitous phenomenon in a wide range of applications, including rain, spray coating, cooling or cleaning, particle encapsulation, inkjet printing, and additive manufacturing. Understanding the dynamics of drop collision is essential for optimizing these processes. In this study, we present a comprehensive experimental and analytical investigation of non-axisymmetric as well as axisymmetric drop impact on a solid particle. We use a high-speed video system to visualize the drop profile during the impact, and measure the drop height and spreading diameter for different liquid viscosities, ratios of the target to drop diameters, offsets, and various other impact parameters. We then develop a theoretical model for drop spreading on a solid spherical particle that relies on the formulation of a remote asymptotic solution for the inviscid flows, generated by non-axisymmetric drop impact. Next, the viscous effects in a thin viscous boundary layer are considered, which allows the formulation of an expression for the residual lamella thickness and maximum spreading. The theoretically predicted evolution of the lamella thickness, the residual film thickness, and the maximum spreading angle agree well with the experimental data presented in this work and the literature. Finally, we present a novel approach for in situ measurement of liquid viscosity, drop impact viscometry, at high shear rates via a single drop impact experiment, with potential application in industries where non-Newtonian drops play a major role, such as pesticide spraying, paint droplet spreading, blood drop impact and fuel injectors.
This retrospective cohort study analyzed differences in rates of central line-associated bloodstream infections (CLABSI) in Black and White inpatients across 11 southeastern US hospitals from 2019 to 2021. Results showed higher CLABSI rates in Black patients during the coronavirus disease 2019 (COVID-19) pandemic, even after adjustment for COVID-19 infection and clinical factors.
We showed images of classic Blalock–Taussig–Thomas shunt in a 35-year-old male patient with tetralogy of Fallot who underwent palliative surgery in 1992. It is a rare image echocardiography in our modern life.
This article provides the first systematic account of relativization in Likpakpaln, an understudied Mabia (Gur) language of Ghana. Broadly speaking, Likpakpaln features two types of relative clauses: restrictive and non-restrictive. Both types of relative clauses are finite and marked by a relative pronoun as well as a clausal definite determiner. The first type is always headed by an indefinite noun. The second is invariably headed by a definite head noun, is additionally marked by a prosodic break, and is usually under focus. The relative pronoun is a composite form comprised of a noun class agreement marker and an invariant relative marker. A number of the features of relative clauses in Likpakpaln align it with other Mabia languages of the region, whereas others distinguish it from these languages. This analysis situates Likpakpaln within its genealogical and areal context while providing new typological perspectives on the Mabia languages as a whole.