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The Duke Activity Status Index is used to assess an individual patient’s perception of their fitness abilities. It has been validated and shown to predict actual fitness in adults but has been studied less in the paediatric population, specifically those with heart disease. This study aims to assess if the Duke Activity Status Index is associated with measured markers of physical fitness in adolescents and young adults with heart disease.
Methods:
This retrospective single-centre cohort study includes patients who completed a minimum of 12 weeks of cardiac rehabilitation between 2016 and 2022. Cardiac rehabilitation outcomes included physical, performance, and psychosocial measures. A comparison between serial testing was performed using a paired t-test. Univariable and multivariable analyses for Duke Activity Status Index were performed. Data are reported as median [interquartile range].
Results:
Of the 118 participants (20 years-old [13.9–22.5], 53% male), 33 (28%) completed at least 12 weeks of cardiac rehabilitation. Median peak oxygen consumption was 60.1% predicted [49–72.8%], and Duke Activity Status Index was 32.6 [21.5–48.8]. On Pearson’s correlation assessing the Duke Activity Status Index, there were significant associations with % predicted peak oxygen consumption (r = 0.49, p < 0.0001), 6-minute walk distance (r = 0.45, p < 0.0001), Duke Activity Status Index metabolic equivalents (r = 0.45, p < 0.0001), and dominant hand grip (r = 0.48, p < 0.0001). In multivariable analysis, the % predicted peak oxygen consumption (r = 0.40, p = 0.005) and dominant hand grip (r = 0.37, p = 0.005) remained statistically significant.
Conclusions:
Duke Activity Status Index is associated with measures of physical fitness in paediatric and young adults with heart disease who complete a cardiac rehabilitation program.
Anthropogenic-mediated climate change is expected to negatively affect pest management in agriculture. Hence, we investigated the oviposition, immature mortality, and developmental processes of Spodoptera species (Spodoptera exigua (Hübner) and Spodoptera litura (Fabricius)) under different temperatures (20, 25, and 30°C) and relative humidity (RH) (30–35, 50–55, 70–75, and 90–95%) conditions. For fecundity, mouths of each Spodoptera species were released into a rectangular box whose inner walls were covered with a sheet of white paper for each combination of temperature and RH. The mouths were kept inside the box to deposit eggs for 72 h. Temperature and RH significantly affected the fecundity, with the maximum number of eggs laid in 70–75% at 30°C. The highest egg and larval mortalities were recorded in 30–35 and 90–95% RH, respectively. Temperature and RH greatly affected the developmental period (egg–adult) and adult emergence rate. The rapid development was recorded in 70–75% RH at 30°C. Higher number of adults was found with an increase in temperature and RH. Adult longevity was significantly higher in 70–75% RH at 20°C. Based on the present study's findings, temperature and RH had an individual apparent effect on the developmental processes of Spodoptera species instead of an interactive effect. Therefore, there is need for an in-depth study of the influence of several climatic factors, including CO2, on the developmental modality and demographic changes of Spodoptera species to assess the impacts of climatic components and the sustainable development of management strategies.
The study analysed 93 samples from four Serbian clay deposits to determine their suitability for ceramics production. The samples were mainly composed of illite and kaolinite. Ternary diagrams were used to classify the samples and evaluate their applicability. Winkler's diagrams, ternary graphs and mineralogical compositions were analysed. The results showed a broader area in these graphs than previously determined for structural ceramics, as well as the potential of these clays for ceramic production. The study used dry-milled, hydraulically semi-dry, pressed and fired samples to assess water absorption and flexural strength and statistical analysis to determine the key parameters influencing final product quality, including that of refractory, wall and floor tiles. This paper evaluates the raw clay materials’ applicability in ceramic production, promoting sustainable use through rapid initial tests, energy savings through dry milling and ecologically sound principles through resource-efficient evaluation.
Venovenous collaterals are abnormal connections between the systemic and pulmonary venous systems. They are commonly seen in the Fontan circulation and may lead to significant hypoxaemia. Transcatheter closure of venovenous collaterals is a potential but controversial treatment as the long-term benefits and outcomes are not well understood.
Methods:
This retrospective cohort study utilised data from the Australian and New Zealand Fontan Registry. Patients who underwent transcatheter venovenous collateral occlusion for hypoxemia from the year 2000 onwards were included. Atriopulmonary and Kawashima-type Fontan circulations were excluded to reflect a more contemporary Fontan cohort.
Results:
Nineteen patients (age 19.3 ± 7.8 years, 53% female) underwent transcatheter venovenous collateral occlusion. Compared to baseline, mean oxygen saturation was improved at latest follow-up (90.5% vs 87.0%; p = 0.003). Nine patients achieved a clinically significant response (defined as an increase of at least 5% to 90% or greater), and this was associated with lower baseline Fontan pressures (12.9 v 15.6 mmHg; p = 0.02). No heart failure hospitalisations, arrhythmia, transplant referrals, or mortality were observed during the median follow-up period of 4 years. Two patients experienced thromboembolic events and five patients underwent re-intervention.
Conclusion:
Transcatheter occlusion of venovenous collaterals in Fontan patients with chronic hypoxaemia resulted in a modest increase in oxygenation over a median follow-up of 4 years and longer-term prognosis did not appear to be adversely affected. Lower Fontan pressures at baseline were associated with a greater improvement in oxygenation.
Elastoinertial turbulence (EIT) is a chaotic flow resulting from the interplay between inertia and viscoelasticity in wall-bounded shear flows. Understanding EIT is important because it is thought to set a limit on the effectiveness of turbulent drag reduction in polymer solutions. Here, we analyse simulations of two-dimensional EIT in channel flow using spectral proper orthogonal decomposition (SPOD), discovering a family of travelling wave structures that capture the sheetlike stress fluctuations that characterise EIT. The frequency-dependence of the leading SPOD mode contains distinct peaks and the mode structures corresponding to these peaks exhibit well-defined travelling structures. The structure of the dominant travelling mode exhibits shift–reflect symmetry similar to the viscoelasticity-modified Tollmien–Schlichting (TS) wave, where the velocity fluctuation in the travelling mode is characterised by large-scale regular structures spanning the channel and the polymer stress field is characterised by thin, inclined sheets of high polymer stress localised at the critical layers near the channel walls. The travelling structures corresponding to the higher-frequency modes have a very similar structure, but are nested in a region roughly bounded by the critical layer positions of the next-lower-frequency mode. A simple theory based on the idea that the critical layers of mode $\kappa$ form the ‘walls’ for the structure of mode $\kappa +1$ yields quantitative agreement with the observed wave speeds and critical layer positions, indicating self-similarity between the structures. The physical idea behind this theory is that the sheetlike localised stress fluctuations in the critical layer prevent velocity fluctuations from penetrating them.
Instability and rupture dynamics of a liquid nano-thread, subjected to external hydrodynamic perturbations, are captured by a stochastic lubrication equation (SLE) incorporating thermal fluctuations via Gaussian white noise. Linear instability analysis of the SLE is conducted to derive the spectra and distribution functions of thermal capillary waves influenced by external perturbations and thermal fluctuations. The SLE is also solved numerically using a second-order finite difference method with a correlated noise model. Both theoretical and numerical solutions, validated through molecular dynamics, indicate that surface tension forces due to specific external perturbations overcome the random effects of thermal fluctuations, determining both the thermal capillary waves and the evolution of perturbation growth. The results also show two distinct regimes: (i) the hydrodynamic regime, where external perturbations dominate, leading to uniform ruptures, and (ii) the thermal-fluctuation regime, where external perturbations are surpassed by thermal fluctuations, resulting in non-uniform ruptures. The transition between these regimes, modelled by a criterion developed from linear instability theory, exhibits a strong dependence on the amplitudes and wavenumbers of the external perturbations.
We study actions of higher rank lattices $\Gamma <G$ on hyperbolic spaces and we show that all such actions satisfying mild properties come from the rank-one factors of G. In particular, all non-elementary isometric actions on an unbounded hyperbolic space are of this type.
The UK welfare landscape is increasingly challenging due to ongoing austerity involving public sector cuts, service retrenchment, and withdrawal of statutory responsibilities. This article shows that as the welfare state contracts, precarity increases and responsibility for service provision is progressively devolved to front-line individuals and service users. To illustrate, the article examines the use of assistive and everyday technologies to improve social housing residents’ quality of life based on a longitudinal mixed methods study conducted between 2020 and 2022. The findings highlight how housing providers can support person-led technology interventions for older residents, where minor improvements positively impact day-to-day living. However, interventions are often limited by practicalities, capacity, and cost. This article connects technological engagement in housing to the ongoing ‘responsibilisation’ of many areas of housing provision to social landlords and tenants. This suggests an extension of responsibility where social housing providers are papering over the cracks in the welfare state.
Natural disturbances influence wetland carbon cycling, and fire is a key driver of terrestrial carbon stocks. However, the influence of fire on wetland carbon cycling remains poorly understood. Here, we investigated how prescribed fire and wildfire impact soil carbon storage in a forested floodplain of south-eastern Australia. We sampled four areas within Murray Valley National Park, the world’s largest river red gum (Eucalyptus camaldulensis) stand, and compared soil carbon (C), nitrogen (N) and C:N ratios between control (unburnt in the 50 years prior to sampling), prescribed burn and wildfire-impacted floodplain areas. Mean soil C and N concentrations were 4.7% ± 0.32% and 0.36% ± 0.02%, respectively, and mean C:N ratios were 14.23 ± 0.33. Carbon concentrations and C:N were highest in control areas of the floodplain, while N concentrations were highest at wildfire-impacted areas. However, flood frequency was a stronger driver of soil C than fire disturbance. Soils at more frequently flooded areas had higher C concentrations compared to less frequently flooded areas, suggesting that resilience to C loss through fire could be enhanced through hydrological restoration. We believe this warrants further research as a potential nature-based climate measure. Mean C density data indicate soil C stocks of 9.4 Tg across Barmah-Millewa Forest, highlighting the significant carbon storage value of this ecosystem.
This paper presents a methodology to design band-pass filters having ultrawide stopband characteristics using multilayer circular substrate-integrated waveguide (SIW) cavities. The orthogonal microstrip feedlines are used as input and output ports that are present at the top and bottom layers, while the middle layers are used to couple the SIW cavities. Higher-order spurious modes of the circular SIW cavity are suppressed by using orthogonal feeding mechanism and properly adjusting the arc-shaped slots between the cavities. To validate the present approach, two filters (second- and fourth-order) have been designed and fabricated and their characteristics are measured. The second-order filter exhibits a stopband rejection below 25 dB up to nearly 5.07f0, while the fourth-order filter has a stopband characteristic of nearly 5.05f0 with 20 dB rejection. The filters allow only TM010 mode propagation and attenuate the higher-order spurious modes of the cavity.
Substantial debate surrounds the relative lack of formal burials in Britain during the fifth century AD, which was a key period of social and economic transition following the withdrawal of the Roman army. Here, the authors argue that the ‘missing fifth century’ may be explained, in part, by the continuation of archaeologically invisible mortuary treatments practised in the preceding Iron Age and Roman period. Compilation of published radiocarbon dates from human remains found in cave and riverine contexts demonstrates that a variety of methods for the disposal of the dead—outside of formal cemeteries—existed in the first millennium AD.
This comment on Moritz Altenried's The Digital Factory discusses how the book offers four interrelated theoretical contributions to the study of labour in the digital economy – redefining the factory, specifying digital Taylorism, materializing its infrastructure, and mapping class relations – through four sites of investigation. The piece discusses the implications of the resulting multiplication of labour and labour relations for reconfigured class relations and resistance and argues that the differentiated social relations across spatial and material contexts ask for a theorization of the conjunctural nature of these relations.
The Second International Mortar Dating Intercomparison Study (MODIS2) took place in 2020. Three mortar samples from different sites and chronologies were distributed among various research groups in form of bulk mortar and grain fraction smaller than 150 µm. This is the first time the Zagreb Radiocarbon Laboratory, with support of the Center of Applied Isotope Studies, University of Georgia, took part in the international mortar intercomparison. The initial approach of the Laboratory to mortar dating was to separate 32–63 µm grain fraction and collect three CO2 gas portions by sequential dissolution with acid. After checking the 14C date trends of the gas portions, which should be ascending with later fractions, the one for the first and shortest gas portion was reported as the age of the mortar. However, the first gas portion might not be true age of the mortar, since it still might contain some “dead” carbon. Therefore, data extrapolation from the first two initial CO2 portions was also conducted on the results, but not reported to the intercomparison. Though in general, all the intercomparison reported dates fit the expected historical ages, for one sample, the extrapolated result showed a better match to the historical data.
Compared to traditional psychosocial interventions, the transdiagnostic approach focuses on common processes or factors that contribute to the development and maintenance of emotional problems. In Spain, the Super Skills Program has proven its effectiveness, but issues with displacement or scheduling for families can hinder access to the intervention. This study aims to examine the program’s effectiveness in preventing children’s psychosocial problems through learning socio-emotional skills when self-administered via the Internet. Participants were 283 Spanish children between the ages of 8 and 12. The children and their parents completed anxiety and depression scales before and after receiving the intervention and 12 months later. The program consisted of 8 self-applied sessions, at a rate of two per week, which included emotional education, cognitive restructuring, self-regulation techniques, training in social skills, problem-solving, and video feedback with cognitive preparation. Significant differences in anxiety and depression symptoms were found after the intervention. A significant reduction in anxiety scores and a marginally significant decrease in depression scores was observed at the long-term follow-up. The “intention to treat” analysis revealed a tendency for children who improved to drop out of the program, completing the intervention children with more symptomathology. Learning socio-emotional skills through a self-applied intervention via the Internet effectively reduced emotional symptoms in school children and is a valuable resource to improve child well-being and prevent future psychological problems.