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To explore current and potential upcoming legal provisions concerning advance healthcare directives in psychiatry in Ireland, with particular focus on clinical challenges and ethical issues (e.g., self-harm, suicide).
Methods:
Review and analysis of selected relevant sections of the Assisted Decision-Making (Capacity) Act 2015, Assisted Decision-Making (Capacity) (Amendment) Act 2022, Mental Health Act 2001, Mental Health Bill 2024, and Criminal Law (Suicide) Act 1993, and relevant publications from Ireland’s Medical Council and Decision Support Service.
Results:
The Assisted Decision-Making (Capacity) Act 2015 outlined new procedures for advance healthcare directives. The Assisted Decision-Making (Capacity) (Amendment) Act 2022 specified that advance healthcare directives relating to mental health are binding for involuntary patients unless involuntary status is based on Section 3(1)(a) of the Mental Health Act 2001 (i.e., the ‘risk’ criteria). The Mental Health Bill 2024 proposes making advance healthcare directives binding for all involuntary patients. In relation to suicide and self-harm, the Criminal Law (Suicide) Act 1993 states that ‘a person who aids, abets, counsels or procures the suicide of another, or an attempt by another to commit suicide, shall be guilty of an offence’, and the Decision Support Service advises that healthcare professionals are exempted from criminal liability if complying with a valid and applicable advance healthcare directive that refuses life-sustaining treatment, even where the directive-maker has attempted suicide.
Conclusions:
Considerable public and professional education are needed if advance healthcare directives are to be widely used. The ethical dimensions of certain advance directives require additional thought and, ideally, professional ethical guidance.
There is a longstanding belief amongst scholars of psychophysiology that activation is positively associated with attention. However, recent work on news avoidance suggests that activation from negative content is linked to decreased attention. The current study seeks to investigate these different expectations and suggests that both increased and decreased activation can be linked to both attention and avoidance. Using an experiment that employs skin conductance levels and heart rate to evaluate subjects’ media selection choices, the author finds that even as deactivation is most likely to precede the decision to turn away from content, roughly 30% of the time activation precedes turning away. These findings confirm prior conclusions from the psychophysiological communications literature, and in the news avoidance literature, but it also highlights the need for more nuanced expectations where activation and media selection are concerned.
Scalable assessment tools for precision psychiatry are of increasing clinical interest. One clinical risk assessment that might be improved by such approaches is assessment of violence perpetration risk. This is an important adverse outcome to reduce for some people presenting to services for first-episode psychosis. A prediction tool (Oxford Mental Illness and Violence (OxMIV)) has been externally validated in these services, but clinical acceptability and role need to be examined and developed.
Aims
This study aimed to understand clinical use of the OxMIV tool to support violence risk management in early intervention in psychosis services in terms of acceptability to clinicians, patients and carers, practical feasibility, perceived utility, impact and role.
Method
A mixed methods approach integrated quantitative data on utility and patterns of use of the OxMIV tool over 12 months in two services with qualitative data from interviews of 20 clinicians and 12 patients and carers.
Results
The OxMIV tool was used 141 times, mostly in new assessments. Required information was available, with only family history items scored unknown to any notable degree. The OxMIV tool was deemed helpful by clinicians in most cases, especially if there were previous risk concerns. It was acceptable practically, and broadly for the service, for which its concordance with clinical judgement was important. Patients and carers thought it could improve openness. There was some limited impact on plans for clinical support.
Conclusions
The OxMIV tool met an identified clinical need to support clinical assessment for violence risk. Linkage to intervention pathways is a research priority.
Understanding complex three-dimensional cardiac structures is the key to knowing CHD. Many learners have limited access to cadaveric specimens, and most alternative teaching modalities are two-dimensional. Therefore, we have developed virtual cardiac models using photogrammetry of actual heart specimens to address this educational need.
Methods:
A descriptive study was conducted at a single institution during a week-long cardiac morphology conference in October 2022 and 2023. Conference attendees viewed virtual cardiac models via laptop screen and virtual reality headset. Learners were surveyed on their opinions of the virtual models and their perceived effectiveness compared to existing educational materials.
Results:
Forty-six learners completed the survey. Participants reported the virtual cardiac models to be more effective than textbook diagrams (60%), and equally or more effective compared to didactic teaching (78%) and specimen videos (78%). Approximately half of participants (54%) found the virtual models to be less effective than hands-on cadaveric specimen inspection. Attitudes towards the virtual specimens were overall positive with most responders finding the tool engaging (87%) and enjoyable (85%). A majority reported that the models deepened their understanding of cardiac morphology (79%) and that they would recommend them to other trainees (87%).
Conclusions:
This study demonstrates that a novel teaching tool, virtual cardiac specimens, is equivalent to or more effective than many current materials for learning cardiac morphology. While they may not replace direct cadaveric specimen review, virtual models are an engaging alternative with the ability to reach a wider audience.
Organizations and managers often implement workplace training programs aimed at fostering collaboration, belonging, and respect among employees. However, the effectiveness of these programs can be undermined when they are framed in ways that only resonate with some participants while alienating others. We propose that moral reframing can enhance the success of such initiatives by aligning messaging with a broader range of moral perspectives. Drawing on moral foundations theory, we identify five key dimensions, care, fairness, loyalty, authority, and purity, that shape how individuals interpret and respond to workplace training efforts. Although many programs emphasize care and fairness, individuals who prioritize loyalty, authority, and purity may perceive them differently, leading to disengagement, skepticism, or resistance. We argue that strategically framing training initiatives across multiple moral frameworks can foster greater engagement, buy-in, and overall effectiveness. Additionally, we offer practical recommendations for organizations to implement moral reframing strategies, ensuring that training efforts resonate with a wider audience and contribute to a more cohesive and productive workplace.
Contemporary business and management research in China has advanced rapidly, making significant strides in the introduction of theoretical frameworks, research methodologies, local theory development, and practical applications. Much of this research continues to draw on Western theories, and since the reform and opening up, Chinese management research has evolved through distinct stages of globalization and localization. Today, it faces new challenges amid anti-globalization trends. At this critical juncture, the key question is whether China should continue integrating Western theories or capitalize on the opportunity to develop indigenous management theories. This paper explores the differences in scientific development concepts and focuses between China and the West, the historical trajectory of Chinese management research, and the challenges and opportunities that lie ahead. To enhance China's contribution to global management research, we propose that it is essential to sustain international collaboration, deepen understanding of frontline enterprise practices, promote micro-level research and interpretation with Chinese characteristics, and cultivate an open academic community, while optimizing the research evaluation system.
Kant’s position in analytical jurisprudence has not been sufficiently explored. This paper aims to remedy this shortcoming. The main issue in this paper is to which extent Kant’s legal theory is an instance of natural law theory or legal positivism. Robert Alexy is one of the few philosophers who addressed this issue. Alexy believes that Kant defends a version of natural law theory that puts moral limits on legal validity. I show that Alexy’s interpretation is unsuccessful. I argue that Kant defends the positivist separability thesis that norms need not meet moral requirements to qualify as legal norms.
Cardiac catheterisation in the postoperative period emerges as a primary tool, providing effectiveness and safety in diagnosis, treatment guidance, and resolution of major residual lesions.
Materials and methods:
This is a retrospective case-control study. We collected the clinical records of patients who underwent cardiac catheterisation between January 2003 and December 2022 within the initial 72 hours after surgery in the pediatric cardiac ICU of a national referral hospital in Mexico City. Descriptive, univariate, and multivariate analyses were performed.
Results:
A total of 6,243 surgeries were performed, of which 264 were cardiac catheterizations carried out within the first 72 hours of the postoperative period;these included 73 diagnostic procedures and 191 interventional procedures. One hundred and thirty-five (135) catheterisations targeted recent suture intervention sites. The primary indications for cardiac catheterisation included low cardiac output and the suspicion of major residual lesions. Approximately 65% of interventions occurred within the first 24 hours and solved 426 residual lesions. No significant associations were found between mortality, complications, and the need for surgical reintervention in patients who underwent interventional catheterisation at recent suture sites (OR 1.93;95% CI:0.94–4.07:p = 0.076). Seventeen patients (17) were extubated in the initial 24 hours post-catheterisation. Two major complications were identified: rupture of the systemic-to-pulmonary shunt in the anastomosis, and a pulmonary artery laceration requiring emergency surgery. One patient died.
Conclusion:
Cardiac catheterisation has evolved into a vital instrument to diagnose and resolve abnormalities and significant residual lesions without increasing the morbidity and mortality risks.
In this paper, we develop an analytical model to investigate the generation of instability waves triggered by the upstream acoustic forcing near the nozzle lip of a supersonic jet. This represents an important stage, i.e. the jet receptivity, of the screech feedback loop. The upstream acoustic forcing, resulting from the shock-instability interaction (SII), reaches the nozzle lip and excites new shear-layer instability waves. To obtain the newly excited instability wave, we first determine the scattered sound field due to the upstream forcing using the Wiener–Hopf technique, with the kernel function factored using asymptotic expansions and overlapping approximations. Subsequently, the unsteady Kutta condition is imposed at the nozzle lip, enabling the derivation of the dispersion relation for the newly excited instability wave. A linear transfer function between the upstream forcing and the newly excited instability wave is obtained. We calculate the amplitude and phase delay in this receptivity process and examine their variations against the frequency. The analytically obtained phase delay enables us to evaluate the phase condition for jet screech and predict the screech frequency accordingly. The results show improved agreement with the experimental data compared with classical models. It is hoped that this model may help in developing a full screech model.
Tetralogy of Fallot is the most common cyanotic congenital malformation of the heart. The right ventricular outflow tract is of great interest in this setting, but most of the focus on this feature has been on the size of the so-called pulmonary valvar “annulus”. We aimed to characterise other aspects of the morphology of the pulmonary root in heart specimens with tetralogy of Fallot.
Methods:
We reviewed archived hearts with tetralogy of Fallot from four registries. The pulmonary root was examined with specific attention to the number of sinuses, the number of leaflets, presence of any fusion of leaflets, and the direction of the zone of apposition between the leaflets. Cluster analyses were then conducted to see if the features permitted segregation into groups.
Results:
We examined a total of 155 hearts. The pulmonary valve had two leaflets in 62%, three leaflets in 34%, and one leaflet in 3%. Irrespective of leaflet morphology, most hearts had two sinuses. Cluster analysis permitted segregation into three groups, with the direction of the zone of apposition being the most important feature for segregation.
Conclusion:
In two-thirds of our hearts with tetralogy of Fallot, the pulmonary valve had two leaflets. Most frequently there were three sinuses. In the setting of a valve with two sinuses, the zone of apposition between the leaflets pointing towards the aorta. Cluster analysis permitted statistically sound segregation of the heart and highlights the importance of delineating these features, specifically the leaflet and sinus morphology, with clinical imaging.
Research published in the last decade, which has provided data from both technological and morphometrical analyses of lithic points from southeastern and southern Brazil and Uruguay, suggests that there is much more cultural diversity among hunter-gatherers during the Early to Mid-Holocene than previously suggested by the Umbu Tradition model. Some of these studies have suggested new archaeological cultures and new definitions of lithic industries. In this article we present new data on another lithic assemblage that we associate with the Garivaldinense lithic industry and is found at the Pedro Fridolino Schmitz site. We also present, for the first time, the definition of two new types of lithic bifacial stemmed points. Our data suggest a low-density occupation of the site from the Middle to Late Holocene (8000–1000 BP) and some variability within the Garivaldinense industry throughout time and space.
When an oblate droplet translates through a viscous fluid under linear shear, it experiences a lateral lift force whose direction and magnitude are influenced by the Reynolds number, the droplet’s viscosity and its aspect ratio. Using a recently developed sharp interface method, we perform three-dimensional direct numerical simulations to explore the evolution of lift forces on oblate droplets across a broad range of these parameters. Our findings reveal that in the low-but-finite Reynolds number regime, the Saffman mechanism consistently governs the lift force. The lift increases with the droplet’s viscosity, aligning with the analytical solution derived by Legendre & Magnaudet (Phys. Fluids, vol. 9, 1997, p. 3572), and also rises with the droplet’s aspect ratio. We propose a semi-analytical correlation to predict this lift force. In the moderate- to high-Reynolds-number regime, distinct behaviours emerge: the $L\hbox{-}$ and $S\hbox{-}$mechanisms, arising from the vorticity contained in the upstream shear flow and the vorticity produced at the droplet surface, dominate for weakly and highly viscous droplets, respectively. Both mechanisms generate counter-rotating streamwise vortices of opposite signs, leading to observed lift reversals with increasing droplet viscosity. Detailed force decomposition based on vorticity moments indicates that in the $L\hbox{-}$mechanism-dominated regime for weakly to moderately viscous droplets, the streamwise vorticity-induced lift approximates the total lift. Conversely, in the $S\hbox{-}$mechanism-dominated regime, for moderately to highly viscous droplets, the streamwise vorticity-induced lift constitutes only a portion of the total lift, with the asymmetric advection of azimuthal vorticity at the droplet interface contributing additional positive lift to counterbalance the $S\hbox{-}$mechanism’s effects. These insights bridge the understanding between inviscid bubbles and rigid particles, enhancing our comprehension of the lift force experienced by droplets in different flow regimes.