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The Asian corn borer, Ostrinia furnacalis, is a major insect pest of maize, causing significant yield losses across maize-growing regions. The excessive reliance on chemical pesticides for its control has raised environmental and resistance-related concerns, emphasising the need for safer and more sustainable alternatives. This study investigates the efficacy of five synthetic volatile organic compounds (VOCs), methyl salicylate, methyl benzoate, methyl eugenol, methyl chavicol, and allyl isothiocyanate, based on their toxic and behavioural effects on O. furnacalis, as well as their impact on the egg parasitoid Trichogramma ostriniae. All tested VOCs significantly increased mortality in both eggs and larvae of O. furnacalis, with a clear dose-dependent trend. Furthermore, all compounds led to a reduction in oviposition by O. furnacalis females under both choice and no-choice conditions in laboratory and greenhouse assays. Behavioural assays revealed that higher concentrations of certain compounds attracted O. furnacalis females. Additionally, all tested concentrations of the VOCs enhanced the foraging activity of T. ostriniae. These findings suggest that VOCs hold promise as components of an ecologically effective pest management strategy by simultaneously suppressing pest development and enhancing the efficacy of biological control agents.
The Asian corn borer (ACB), Ostrinia furnacalis (Guenée, 1854), is a serious pest of several crops, particularly a destructive pest of maize and other cereals throughout most of Asia, including China, the Philippines, Indonesia, Malaysia, Thailand, Sri Lanka, India, Bangladesh, Japan, Korea, Vietnam, Laos, Myanmar, Afghanistan, Pakistan and Cambodia. It has long been known as a pest in South-east Asia and has invaded other parts of Asia, Solomon Islands, parts of Africa and certain regions of Australia and Russia. Consequently, worldwide efforts have been increased to ensure new control strategies for O. furnacalis management. In this article, we provide a comprehensive review of the ACB covering its (i) distribution (geographic range and seasonal variations), (ii) morphology and ecology (taxonomy, life-history, host plants and economic importance) and (iii) management strategies (which include agroecological approaches, mating disruption, integrated genetic approaches, chemical as well as biological control). Furthermore, we conclude this review with recommendations to provide some suggestions for improving eco-friendly pest management strategies to enhance the sustainable management of ACB in infested areas.
Genetic information is widely recognised as being particularly sensitive personal information about an individual and his or her family. This article presents an analysis of the privacy policies of Australian companies that were offering direct-to-consumer genetic testing services in 2012–13. The results of this analysis indicate that many of these companies do not comply with the Privacy Act 1988 (Cth), and will need to significantly reassess their privacy policies now that significant new amendments to the Act have come into force. Whilst the Privacy Commissioner has increased powers under the new amendments, the extent to which these will mitigate the deficiencies of the current regime in relation to privacy practices of direct–to-consumer genetic testing companies remains unclear. Accordingly, it may be argued that a privacy code for the direct-to-consumer genetic testing industry would provide clearer standards. Alternatively it may be time to rethink whether a sui generis approach to protecting genetic information is warranted.
We examined how relative language dominance impacts Spanish–English bilinguals’ crosslinguistic and nonlinguistic interference resolution abilities during a web-based Spanish picture-word interference naming task and a subsequent spatial Stroop paradigm, and the relationship between the two. Results show the expected interference and facilitation effects in the online setting across both tasks. Additionally, participants with greater English dominance had larger within-language, Spanish facilitation and marginally larger crosslinguistic (English to Spanish) interference effects reflected on accuracy performance. Similarly, participants with greater English dominance had larger nonlinguistic congruency facilitation effects. Our results are in line with other studies finding a relation between linguistic and nonlinguistic cognitive control. Correlated reaction time performance between the linguistic and nonlinguistic paradigms suggests that overcoming crosslinguistic interference may be partly based on cognitive control processes used outside of language. Modulations by language dominance underline the importance of accounting for relative language proficiency in bilinguals’ two languages when studying bilingualism.
Three-dimensional (3-D) clustering characteristics of large-Stokes-number sprays interacting with turbulent swirling co-flows are investigated experimentally. The astigmatic interferometric particle imaging (AIPI) technique is used for simultaneous measurement of the spray droplets position in 3-D space and their corresponding diameter. The Stokes number estimated based on the Kolmogorov time scale varies from 34 to 142. The results show that the degree of droplet clustering plateaus at about 0.4 and at large Stokes numbers. It is obtained that the mean length scale of the clusters normalized by the Kolmogorov length scale follows a power-law relation, and the mean void length scale normalized by the integral length scale plateaus at about 1.5 and at large Stokes numbers. It is shown that the ratio of the number density of the droplets residing within the clusters to the global number density increases with increasing Stokes number and is about 8 for the largest Stokes number examined in this study. The joint characteristics of cluster's normalized volume and the mean diameter of droplets residing within the clusters show that small-volume clusters accommodate droplets with a relatively broad range of diameters. However, large clusters carry droplets with the most probable diameter. The developed AIPI technique in the present study and the corresponding spray characteristics are of importance for engineering applications that aim to understand the 3-D clustering characteristics of large-Stokes-number droplets sprayed into turbulent swirling co-flows.
Dengue fever is a viral disease caused by one of four dengue stereotypes (Flavivirus: Flaviviridae) that are primarily transmitted by Aedes albopictus (Skuse) and Aedes aegypti (L.). To safeguard public health, it is crucial to conduct surveys that examine the factors favouring the presence of these species. Our study surveyed 42 councils across four towns within the Bhakkar district of Punjab Province, by inspecting man-made or natural habitats containing standing water. First, door-to-door surveillance teams from the district health department were assigned to each council to surveillance Aedes species and dengue cases. Second, data collection through surveillance efforts, and validation procedures were implemented, and the verified data was uploaded onto the Dengue Tracking System by Third Party Validation teams. Third, data were analysed to identify factors influencing dengue fever cases. The findings demonstrated the following: (1) Predominantly, instances were discerned among individuals who had a documented history of having travelled beyond the confines of the province. (2) Containers associated with evaporative air coolers and tyre shops were responsible for approximately 30% of the Aedes developmental sites. (4) Variability in temperature was responsible for approximately 45% of the observed differences in the quantity of recorded Aedes mosquito developmental sites. (5) Implementation of dengue prevention initiatives precipitated a 50% reduction in Aedes-positive containers, alongside a notable 70% decline in reported cases of dengue fever during the period spanning 2019 to 2020, while the majority of reported cases were of external origin. Aedes control measures substantially curtailed mosquito populations and lowered vector-virus interactions. Notably, local dengue transmission was eliminated through advanced and effective Aedes control efforts, emphasising the need for persistent surveillance and eradication of larval habitats in affected regions.
Lateralisation is a well-established phenomenon observed in an increasing number of insect species. This study aims to obtain basic details on lateralisation in courtship and mating behaviour in Ostrinia furnacalis, the Asian corn borer. We conducted laboratory investigations to observe lateralisation in courtship and mating behaviours in adult O. furnacalis. Our goal was also to detect lateralised mating behaviour variations during sexual interactions and to elucidate how these variances might influence the mating success of males. Our findings reveal two distinct lateralised traits: male approaches from the right or left side of the female and the direction of male turning displays. Specifically, males approaching females from their right side predominantly exhibited left-biased 180° turning displays, while males approaching females from the left-side primarily displayed right-biased 180° turning displays. Notably, left-biased males, executing a 180° turn for end-to-end genital contact, initiated copulation with fewer attempts and began copulation earlier than their right-biased approaches with left-biased 180° turning displays. Furthermore, mating success was higher when males subsequently approached the right side of females during sexual encounters. Left-biased 180° turning males exhibited a higher number of successful mating interactions. These observations provide the first report on lateralisation in the reproductive behaviour of O. furnacalis under controlled laboratory conditions and hold promise for establishing reliable benchmarks for assessing and monitoring the quality of mass-produced individuals in pest control efforts.
Chronic kidney disease (CKD), also known as chronic renal disease, is a condition characterized by a gradual loss of kidney function over time. It is a common condition often associated with getting older, but it can affect anyone [1]. The causes are manifold, including kidney diseases, diabetic nephropathy and diabetes, hypertension, immunopathologies like systemic lupus erythematosus (SLE) with and without anti-phospholipid antibodies and kidney transplantation (uncomplicated, complicated).
Availability of long-term psychological interventions for personality disorders is limited because of their high intensity and cost. Research in evidence-based, low-intensity interventions is needed.
Aims
This study aimed to examine the feasibility, acceptability and potential impact of a low-intensity, digital guided self-help (GSH) intervention that is focused on emotion regulation, recovery-oriented and provides in-the-moment delivery for patients with personality disorders.
Method
We conducted a single-blind feasibility trial. A total of 43 patients with a personality disorder were recruited and randomly assigned to either a GSH arm (n = 22) or a treatment-as-usual arm (n = 21). The GSH intervention included a series of short videos offering psychoeducation and support, personalised feedback using text messages, and supportive telephone calls, for 4 weeks in addition to treatment as usual. Outcomes of emotional disturbance, emotion dysregulation, self-harm behaviours and decentring ability were measured at baseline, 4 weeks (end of intervention) and 8 weeks (follow-up).
Results
All patients who attended the first session continued until the last session. There was an interaction effect between time and group on anxiety (P = 0.027, Δη2 = 0.10), where the GSH group showed a significant reduction in anxiety at follow-up (P = 0.003, d = 0.25). The GSH group increased in decentring ability at the end of intervention (P = 0.007, d = −0.65), and the decrease in self-harm behaviours continued until follow-up (P = 0.02, d = 0.57).
Conclusions
The results suggest that a personalised digital GSH with a focus on recovery could reduce anxiety and self-harm behaviours at short-term follow-up.
In live coding, the code can be considered as an archetypal form of score that notates formal processes. We aimed at investigating the possibility of using graphic visuals as a complementary form of descriptive score by visualising sound events using different time representations. To this end, we devised two visualisation systems (Time_X and Time_Z). Time_X represents time along the x-axis, while in Time_Z the objects overlap along an imaginary z-axis. Based on our previous personal experience with the system, such forms of visual scores can help to develop new musicking strategies while live coding. In this article, we wanted to broaden such reflections, and we used them as probes in a study with three live coders. After tailoring the two systems to the usual practice of the three participants, we asked them to use the systems for three weeks and keep a diary. At the end, we interviewed them. Based on their comments, we present some reflections on the use of graphic forms of visualisation in live coding, on how they can support musicking process, and to what extent such visuals can be considered scores.
Separate and joint droplets, clusters, and voids characteristics of sprays injected in a turbulent co-flow are investigated experimentally. Simultaneous Mie scattering and interferometric laser imaging for droplet sizing along with separate hotwire anemometry are performed. The turbulent co-flow characteristics are adjusted using zero, one or two perforated plates. The Taylor-length-scale-based Reynolds number varies from 10 to 38, and the Stokes number estimated based on the Kolmogorov time scale varies from 3 to 25. The results show that the mean length scale of the clusters normalized by the Kolmogorov length scale varies linearly with the Stokes number. However, the mean void length scale is of the order of the integral length scale. It is shown that the number density of the droplets inside the clusters is approximately 7 times larger than that in the voids. The ratios of the droplets number densities in the clusters and voids to the total number density are independent of the test conditions and equal 5.5 and 0.8, respectively. The joint probability density function of the droplets diameter and clusters area shows that the droplets with the most probable diameter are found in the majority of the clusters. It is argued that intensifying the turbulence broadens the range of turbulent eddy size in the co-flow which allows for accommodating droplets with a broad range of diameters in the clusters. The results are of significance for engineering applications that aim to modify the clustering characteristics of large-Stokes-number droplets sprayed into turbulent co-flows.
At the 2022 meeting of the American Society for Bioethics and Medical Humanities, a new affinity group was formed: astrobioethics. This is the branch of bioethics for space exploration, extraterrestrial environments and possible extraterrestrial organisms. Bioethics has traditionally operated from Western/Global North dominated thought structures and it is difficult to introduce alternative frameworks. However, astrobioethics is forming and is primed to include alternative frameworks, such as pre-Columbian Indigenous American philosophy/ethics and Global South frameworks and knowledge.
Methods
The methods utilized include Indigenous research methodologies and standpoint, an overview of Indigenous American philosophy/ethics, and reflection on how this may impact astrobioethical considerations of space exploration.
Discussion and Conclusions
Indigenous philosophies and ethics consider space exploration and its associated risks and impacts on potential extraterrestrial lifeforms, systems and environments. The nuances of using terms like ‘colonization’ are considered and the paper concludes by considering how Méxica philosophical concepts and the four main Indigenous pragmatic dimensions can interact with established bioethical principles to guide future space exploration.
Background: CT angiogram of the head and neck (CTA) is not part of the routine work-up of status epilepticus (SE), which could miss acute ischemic stroke (AIS) as the cause. We hypothesized that healthcare savings from early treatment of otherwise undiagnosed AIS would be greater than the cost of adding a routine CTA for work-up of SE (all comers). Methods: The total number of patients presenting to ER with SE (defined as seizure/epilepsy+hospital admission), and the subgroup who were diagnosed with a new ischemic stroke, or received a CTA were retrospectively calculated at the Ottawa Hospital between 2010-2019. CTA costs, and savings of early treatment of AIS were obtained from the Department of Radiology and literature review, respectively. Results: 727 individuals presented with SE. 3% (n=22) had a new ischemic stroke-of these, 95% (n=21) did not receive a CTA (considered missed AIS). Assuming CTA could help detect every case of ischemic stroke missed this could result in 2.27 additional strokes caught early/year, and assuming if all thrombolysis candidates this would net cost $7,967/year (vs no acute treatment), or if all thrombolysis+thrombectomy candidates would net save $19,823/year (vs thrombolysis alone). Conclusions: Routine CTA in SE in the ER has potential to result in healthcare savings.
This article traces the development and growth of health justice partnerships (HJPs) in three countries: the United States, Australia and the United Kingdom.
Insertable cardiac monitors are minimally invasive devices designed for implantation in the chest wall of patients to record heart rhythms and relate them to symptoms over prolonged periods. The Jot Dx™ (Abbott Laboratories, Abbott Park, IL, USA) is the latest Food and Drug Administration-cleared insertable cardiac monitor that is Bluetooth™ enabled allowing for near-immediate transmission of data from patients to physicians. We report on the first paediatric patient, in a patient weighing 11.7 kg, to undergo a modified, vertical, parasternal implantation of a Jot Dx™.
Commercial pigs kept outdoors are often given nose-rings, to inhibit rooting and minimize pasture damage. If rooting is a ‘behavioural need’ in the pig, and ringing is effective because it renders rooting painful, nose-ringing may be a threat to welfare. Thirty gestating sows were assigned to one of three conditions: unringed controls (UR); sows ringed with three, wire ‘clip’ rings through the snout rim (CR); or sows with one, rigid ‘bull’ ring (BR). They were observed on grass for 7h day−1 at intervals over 6 months. Ringing almost totally abolished penetration of the ground by rooting during the month after ringing (UR, CR and BR sows respectively spent 5.6%, 0.1% and 0.1 % of scan observations dig-rooting during this month; P < 0.001). These differences in recorded rooting were reflected in a much greater extent of pasture damage in paddocks containing UR sows. Rooting remained largely suppressed throughout the 6 months of observations in BR sows; but substantial recovery of this function occurred in CR sows by the sixth month, although much of this may be attributed to the fact that most sows lost at least some of their rings. Ringing also partially inhibited grazing (which accounted for 26.2%, 27.1% and 21.9 % of scans over the whole project in UR, CR and BR sows respectively; P < 0.05), nosing in straw, digging out wallows and stone-chewing (18.3%, 9.5% and 9.2% respectively of all scans in UR, CR and BR sows; P < 0.001). Ringed sows spent more time standing but otherwise inactive than did controls (0.8%, 1.7% and 4.0% of all scans in UR, CR and BR sows respectively; P < 0 .001), and displayed more straw-chewing, vacuum-chewing and digging at soil with the forepaw. We conclude that nose-ringing in pigs inhibited a range of functional activities, as well as rooting, and elicited more behaviours that suggest a degree of reduced welfare. BR sows displayed more of these effects than did CR ones, although these differences may be largely, but not entirely, due to a loss of clip rings over time.
In this paper, we propose an approach to tune optimal parameters of a robust PID controller by means of computed torque control (CTC) strategy for trajectory tracking of a Delta parallel robot, using a hybrid optimization algorithm of Particle Swarm Optimization (PSO) and differential evolution (DE). It differs from previous works that they propose robust PID controller parameters tuning based on conventional gradient-based optimization algorithms and apply them to process control. First, we reduce the tuning problem of a robust PID controller with CTC strategy satisfying requirements including robustness and disturbance attenuation to an optimization problem with nonlinear constraints by considering the nonlinear dynamic model of a Delta parallel robot. Second, we set up the design characteristics for the trajectory tracking of a Delta parallel robot. Then, we propose a robust PID controller in a way of obtaining the global optimization solution of the nonlinear optimization problem by running a PSO-DE hybrid optimization algorithm of finding the global optimal solution by maintaining the diversity of swarm during evolution based on the evolution of cognitive experience. Simulation and experimental results demonstrate that the proposed controller outperforms previous works with respect to robust performance and active disturbance attenuation when it is applied to tracking control of a Delta parallel robot.
Layers 12 and 13 of the Chongphadae Cave site located northwest of the central part of the Korean Peninsula include human fossils, fireplaces, a great number of lithic artefacts, and mammal remains. These layers represent new evidence for the paleoenvironment, human occupation, and activities in this region during the late MIS 3 and MIS 2, associated with global cold and dry climate, respectively. Most of lithic artefacts collected are flake tools. Raw material selection, lithic reduction technology, and lithic industry represent peculiar local characteristics. Our analysis of faunal assemblages also suggests that the Chongphadae region had a rich ecosystem capable of forming a diverse mammalian fauna including ungulates (mainly deer and horses) during this period. It is likely that the mosaic landscapes, including grasslands, forests, rivers, and wetlands, provided a favorable environment for humans, as well as mammals and plants, and the occupants of the site actively hunted and gathered in a relatively temperate environment. Our study suggests that the central Korean Peninsula was not severely affected by global dry and cold events such as LGM, although it was a somewhat humid and cold environment during the late MIS 3 and MIS 2. The central Korean Peninsula may have existed as an unknown refugium (or area of endemism) in northeastern Asia during this time.
In the era of sentencing guidelines, the punishment for traffickers is primarily based on the offenders’ culpability and the drug weight. Existing literature tend to focus on the issue of proportionality as it relates to the roles and culpability of offenders. However, little attention has been drawn to the quantity of drugs. England and Wales have incorporated offender roles into their sentencing guidelines, while Hong Kong uses drug tariffs strictly based on drug weight to calculate the starting point of a sentence. Using a novel equation called ‘the arithmetic starting point of sentence’, this study examines the starting sentence based on each gram of drugs by undertaking a comparative analysis of the respective jurisdictions. The results show that both jurisdictions have adopted sentencing guidelines that exhibit a logarithmic curve. This implies that the scale used to measure the quantity of drugs is disproportionate, penalising smaller quantities more harshly than larger quantities.
This study aimed to investigate the association between hyperemesis gravidarum (HG) severity and early enteral tube feeding on cardiometabolic markers in offspring cord blood. We included women admitted for HG, who participated in the MOTHER randomised controlled trial (RCT) and observational cohort. The MOTHER RCT showed that early enteral tube feeding in addition to standard care did not affect symptoms/birth outcomes. Among RCT and cohort participants, we assessed how HG severity affected lipid, c-peptide, glucose and free thyroxine cord blood levels. HG severity measures were severity of vomiting at inclusion and 3 weeks after inclusion, pregnancy weight gain and 24-h energy intake at inclusion, readmissions and duration of hospital admissions. Cord blood measures were also compared between RCT participants allocated to enteral tube feeding and those receiving standard care. Between 2013-2016, 215 women were included: 115 RCT and 100 cohort participants. Eighty-one cord blood samples were available. Univariable not multivariable regression analysis showed that lower maternal weight gain was associated with higher cord blood glucose levels (β: –0·08, 95% CI –0·16, –0·00). Lower maternal weight gain was associated with higher Apo-B cord blood levels in multivariable regression analysis (β: –0·01, 95% CI –0·02, –0·01). No associations were found between other HG severity measures or allocation to enteral tube feeding and cord blood cardiometabolic markers. In conclusion, while lower maternal weight gain was associated with higher Apo-B cord blood levels, no other HG severity measures were linked with cord blood cardiometabolic markers, nor were these markers affected by enteral tube feeding.