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Globally, glaciers are changing in response to climate warming, with those that terminate in water often undergoing the most rapid change. In Alaska and northwest Canada, proglacial lakes have grown in number and size but their influence on glacier mass loss is unclear. We characterized the rates of retreat and mass loss through frontal ablation of 55 lake-terminating glaciers (>14 000 km2) in the region using annual Landsat imagery from 1984 to 2021. We find a median retreat rate of 60 m a−1 (interquartile range = 35–89 m a−1) over 1984–2018 and a median loss of 0.04 Gt a−1 (0.01–0.15 Gt a−1) mass through frontal ablation over 2009–18. Summed over 2009–18, our study glaciers lost 6.1 Gt a−1 to frontal ablation. Analysis of bed profiles suggest that glaciers terminating in larger lakes and deeper water lose more mass to frontal ablation, and that the glaciers will remain lake-terminating for an average of 74 years (38–177 a). This work suggests that as more proglacial lakes form and as lakes become larger, enhanced frontal ablation could cause higher mass losses, which should be considered when projecting the future of lake-terminating glaciers.
We measured sex differences in emotion regulation (ER) abilities – relying on exercise of cognitive reappraisal – during an image rating task in adults over 55 years of age with varying degrees of depression symptom severity. We also collected a self-report measure on participants' views of their own ER capacities. Previous research by this group has demonstrated the importance of emotion processing in the context of sex and aging in depression. We hypothesized that females would (1) score higher on the Cognitive Reappraisal Facet of the ERQ, (2) be more successful in utilizing cognitive reappraisal skills in response to negative stimuli; and (3) have self-report scores on the ERQ that more closely match their success at cognitive reappraisal than would males.
Participants and Methods:
capacities. Previous research by this group has demonstrated the importance of emotion processing in the context of sex and aging in depression. We hypothesized that females would (1) score higher on the Cognitive Reappraisal Facet of the ERQ, (2) be more successful in utilizing cognitive reappraisal skills in response to negative stimuli; and (3) have self-report scores on the ERQ that more closely match their success at cognitive reappraisal than would males.
Results:
Only the first of our three outcome measures was successfully predicted by the model including age, MADRS scores, and sex as predictors. Scores on the ERQ cognitive reappraisal facet with sex accounted for 11.3% of the variance (F=7.344, p=.009). Age and depression symptom severity did not reach significance. Performance on the ERT itself and the correlation between the two were not meaningfully modeled.
Conclusions:
Women showed both better cognitive reappraisal abilities overall and more insight into the level of those abilities, findings that fall in line with most ER literature. However, we found that females were also more likely than males to be skewed in the positive or “overconfident” direction; to overestimate those same abilities. This information is useful for clinicians interpreting self-report information in the emotion regulation domain. These findings may not generalize to a more diverse (racially and socioeconomically) population and given the cognitive nature of the reappraisal strategy; these results may not extend to a less educated population. These data will be useful to inform the interpretation of fMRI images from this same experiment.
Among the multitude of enemies facing the newly born English republic, the Presbyterians of Ulster posed a threat at once ideological and military. Such supporters of the new regime as John Milton derided the “blockish presbyters” of a “remote” province and denounced them as Scottish intruders upon English soil. But the threat they posed lay not only in their capacity to mobilize an armed population but to do so around religious and political positions drawn from a common stock of ideas present across the three kingdoms. The twin dangers could be made to serve polemical purposes within domestic English debate as the Commonwealth sought to counter the religious ambitions and constitutional challenges of those they branded as “Scottified” Presbyterians. In Ulster, the short-lived Presbyterian “revolt” proved a remarkable though fleeting success. Its proponents cultivated these transplanted ideas into fertile if fragile growth in the form of armed organization and communal mobilization. This episode attests to the importance of localizing ideology in precise contexts, and to the fact that print was only one vector, if a vital one, for its transmission.
Recently, artificial intelligence-powered devices have been put forward as potentially powerful tools for the improvement of mental healthcare. An important question is how these devices impact the physician-patient interaction.
Aims
Aifred is an artificial intelligence-powered clinical decision support system (CDSS) for the treatment of major depression. Here, we explore the use of a simulation centre environment in evaluating the usability of Aifred, particularly its impact on the physician–patient interaction.
Method
Twenty psychiatry and family medicine attending staff and residents were recruited to complete a 2.5-h study at a clinical interaction simulation centre with standardised patients. Each physician had the option of using the CDSS to inform their treatment choice in three 10-min clinical scenarios with standardised patients portraying mild, moderate and severe episodes of major depression. Feasibility and acceptability data were collected through self-report questionnaires, scenario observations, interviews and standardised patient feedback.
Results
All 20 participants completed the study. Initial results indicate that the tool was acceptable to clinicians and feasible for use during clinical encounters. Clinicians indicated a willingness to use the tool in real clinical practice, a significant degree of trust in the system's predictions to assist with treatment selection, and reported that the tool helped increase patient understanding of and trust in treatment. The simulation environment allowed for the evaluation of the tool's impact on the physician–patient interaction.
Conclusions
The simulation centre allowed for direct observations of clinician use and impact of the tool on the clinician–patient interaction before clinical studies. It may therefore offer a useful and important environment in the early testing of new technological tools. The present results will inform further tool development and clinician training materials.
Understanding differences in social-emotional behavior can help identify atypical development. This study examined the differences in social-emotional development in children at increased risk of an autism spectrum disorder (ASD) diagnosis (infant siblings of children diagnosed with the disorder). Parents completed the Brief Infant-Toddler Social-Emotional Assessment (BITSEA) to determine its ability to flag children with later-diagnosed ASD in a high-risk (HR) sibling population. Parents of HR (n = 311) and low-risk (LR; no family history of ASD; n = 127) children completed the BITSEA when their children were 18 months old and all children underwent a diagnostic assessment for ASD at age 3 years. All six subscales of the BITSEA (Problems, Competence, ASD Problems, ASD Competence, Total ASD Score, and Red Flags) distinguished between those in the HR group who were diagnosed with ASD (n = 84) compared to non-ASD-diagnosed children (both HR-N and LR). One subscale (BITSEA Competence) differentiated between the HR children not diagnosed with ASD and the LR group. The results suggest that tracking early social-emotional development may have implications for all HR children, as they are at increased risk of ASD but also other developmental or mental health conditions.
Glacier basal motion is responsible for the majority of ice flux on fast-flowing glaciers, enables rapid changes in glacier motion and provides the means by which glaciers shape alpine landscapes. In an effort to enhance our understanding of basal motion, we investigate the evolution of glacier velocity and ice-marginal lake stage on Kennicott Glacier, Alaska, during the spring–summer transition, a time when subglacial drainage is undergoing rapid change. A complicated record of > 50 m fill-and-drain sequences on a hydraulically-connected ice-marginal lake likely reflects the punctuated establishment of efficient subglacial drainage as the melt season begins. The rate of change of lake stage generally correlates with diurnal velocity maxima, both in timing and magnitude. At the seasonal scale, the up-glacier progression of enhanced summer basal motion promotes uniformity of daily glacier velocity fluctuations throughout the 10 km study reach, and results in diurnal velocity patterns suggesting increasingly efficient meltwater delivery to and drainage from the subglacial channel system. Our findings suggest the potential of using an ice-marginal lake as a proxy for subglacial water pressure, and show how widespread basal motion affects bulk glacier behavior.
Rapid, non-destructive methods for measuring seed germination and vigour are valuable. Standard germination and seed vigour were determined using 81 soybean seed lots. From these data, seed lots were separated into high and low germinating seed lots as well as high, medium and low vigour seed lots. Near-infrared spectra (950–1650 nm) were collected for training and validation samples for each seed category and used to create partial least squares (PLS) prediction models. For both germination and vigour, qualitative models provided better discrimination of high and low performing seed lots compared with quantitative models. The qualitative germination prediction models correctly identified low and high germination seed lots with an accuracy between 85.7 and 89.7%. For seed vigour, qualitative predictions for the 3-category (low, medium and high vigour) models could not adequately separate high and medium vigour seeds. However, the 2-category (low, medium plus high vigour) prediction models could correctly identify low vigour seed lots between 80 and 100% and the medium plus high vigour seed lots between 96.3 and 96.6%. To our knowledge, the current study is the first to provide near-infrared spectroscopy (NIRS)-based predictive models using agronomically meaningful cut-offs for standard germination and vigour on a commercial scale using over 80 seed lots.
Water is the foundation of all ecosystems, whether terrestrial or aquatic. In terrestrial ecosystems freshwater not only provides critical water supply for transpiration during plant photosynthesis and drinking water for animals, but also transports, redistributes and stores energy, nutrients and contaminants. In aquatic and snow ecosystems, water is the medium in which the ecosystem functions and so its state mediates all transactions in these systems. Ecosystems are not passive responders to water but through their structure and function can manage water and associated microclimate – forests, grasslands, organic terrain wetlands, and beaver ponds being just a few examples.
This chapter will examine the surface water budget in terms of the water continuity equation as a manifestation of the hydrological cycle. To solve the continuity equation for water, the chapter will review hydrological processes and how they interact with vegetation, animals, soils, geomorphology and climate in the context of the catchment. The coupling of the mass and energy continuity equations in controlling hydrological processes will be discussed. How hydrological processes and their ecosystem interactions are managed by humans will be introduced. Then the chapter will review calculation schemes for the surface water budget via one-dimensional land surface schemes and catchment-based hydrological models, noting the data requirements, uncertainty and limitations of these models and the balance required between model complexity and physical representation of hydrology. This will give the conceptual ideas and basic mathematics of conservation laws and transport processes that form the basis of many models in the forthcoming chapters.
Hydrological Processes as a Fundamental Component of Aquatic and Terrestrial Ecosystems
Hydrological Cycle
The hydrological cycle is the flow and storage of water, as liquid, solid or vapor, on and near the Earth's surface. This cycling is a fundamental function of the Earth system and, through its associated latent energy transformations and other influences on land surface characteristics, ensures the habitability of the planet. A representation of the global hydrological cycle is found in Figure 4.1 where it can be seen that there are substantial flows between ocean and land – evaporation and river discharge from land transfer water directly to the oceans or through precipitation and ocean water is evaporated and then forms precipitation over land.
Tungsten is one the most important material for both plasma facing and structural applications in current designs for advanced divertors. Recent work has shown that composites can be manufactured from nanostructured tungsten foils which show significantly higher toughness than monolithic tungsten, but there is no data on the radiation resistance of such materials. In this study W-5 wt% Re foil in both an as rolled and annealed condition was implanted with 2MeV W+ ions to two damage levels, 0.07 and 0.4 dpa. The change in hardness was measured using nanoindentation. An increase in hardness was seen in both materials at both damage levels, with more hardening seen for the 0.4 dpa implanted samples. However the increase in hardness due to ion implantation was 2.6 times higher in the annealed material as compared to the as rolled material. This is due to the smaller grain size and higher dislocation density providing more sinks for the irradiation produced defects in the as rolled material as compared to the annealed material. Thus showing that unannealed tungsten foils are superior for use in applications in which they will see significant levels of radiation damage.
The fracture behaviour of individual grain boundaries has been studied in order to understand the mechanisms controlling stress corrosion cracking in nuclear reactors. In particular, the role of oxidation in facilitating crack initiation and propagation has been reviewed. Nickel alloys from pressurized water reactors (PWRs) have been tested in simulated primary water conditions to induce grain boundary oxidation. Microcantilevers containing an oxidized grain boundary plane have been prepared and tested for fracture. The brittle nature of the oxide was demonstrated and the required stress to fracture measured.
Model alloys have been made of pure W and 1% & 5% W-Ta and W-Re. Indentation hardness and modulus data were obtained by nanoindentation to assess the effect of composition on mechanical properties. Results showed that both the Ta and Re compositions hardened with increasing alloy content, greater in the W-5%Ta composition which showed an increase of 1.03GPa (17%), compared to a 0.43GPa (7%) increase in W-5%Re. The samples also showed very small increases in modulus of ∼ 25GPa (6%) in both W-5%Re and W-5%Ta. The samples were implanted with 3000appm concentration of helium. All samples show a substantial increase in hardness of up to 107% in the case of pure W. An appreciable difference in modulus is also seen in all samples. Initial TEM work has shown no visible He bubbles, suggesting that the mechanical properties changes are due to He-vacancy cluster formation below the resolvable limit.
We examined surveillance data to describe the epidemiology of tuberculosis (TB) among healthcare workers (HCWs) in the United States during the period 1995–2007.
Design.
Cross-sectional descriptive analysis of existing surveillance data.
Setting and Participants.
TB cases reported to the Centers for Disease Control and Prevention from the 50 states and the District of Columbia from 1995 through 2007.
Results.
Of the 200,744 reported TB cases in persons 18 years of age or older, 6,049 (3%) occurred in individuals who were classified as HCWs. HCWs with TB were more likely than other adults with TB to be women (unadjusted odds ratio [95% confidence interval], 4.1 [3.8–4.3]), be foreign born (1.3 [1.3–1.4]), have extrapulmonary TB (1.6 [1.5–1.7]), and complete TB treatment (2.5 [2.3–2.8]).
Conclusions.
Healthcare institutions may benefit from intensifying TB screening of HCWs upon hire, especially persons from countries with a high incidence of TB, and encouraging treatment for latent TB infection among HCWs to prevent progression to TB disease.