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Recent excavations by the Ancient Southwest Texas Project of Texas State University sampled a previously undocumented Younger Dryas component from Eagle Cave in the Lower Pecos Canyonlands of Texas. This stratified assemblage consists of bison (Bison antiquus) bones in association with lithic artifacts and a hearth. Bayesian modeling yields an age of 12,660–12,480 cal BP, and analyses indicate behaviors associated with the processing of a juvenile bison and the manufacture and maintenance of lithic tools. This article presents spatial, faunal, macrobotanical, chronometric, geoarchaeological, and lithic analyses relating to the Younger Dryas component within Eagle Cave. The identification of the Younger Dryas occupation in Eagle Cave should encourage archaeologists to revisit previously excavated rockshelter sites in the Lower Pecos and beyond to evaluate deposits for unrecognized, older occupations.
Positive affect and anhedonia are important but challenging targets for mental health treatments. Previous research indicates the potential of a computerised cognitive training paradigm involving generation of positive mental imagery, termed positive mental imagery training (PMIT), to increase positive affect and reduce anhedonia.
Aims
Our main aim was to investigate the feasibility of PMIT as a positive affect-focused, transdiagnostic adjunct to treatment as usual for patients in in-patient mental health settings.
Method
We ran an open feasibility, randomised controlled trial with three parallel arms: treatment as usual; treatment as usual plus PMIT; and treatment as usual plus an active comparator, cognitive control training. Fifty-seven patients from two different in-patient mental health treatment clinics in Germany were randomised in a 1:1:1 ratio. PMIT and cognitive control training comprised an introductory session followed by eight 15-min training sessions over 2 weeks. Clinical outcomes such as positive affect (primary outcome measure) and anhedonia were assessed at pre- and post-training, and at a further 2-week follow-up.
Results
Adherence was good and attrition was low. The patterns of results for the outcome data were not consistent with a specific effect of PMIT on positive affect, but were more consistent with a specific effect on anhedonia.
Conclusions
The results indicate feasibility and potential promise of a larger efficacy trial investigating PMIT as a treatment adjunct in in-patient mental health settings. Limitations include lack of researcher blinding, small sample size and lack of pre-specified feasibility outcomes. Anhedonia may be a more suitable primary outcome for a future larger trial.
Research on the etiology of dyslexia typically uses an approach based on a single core deficit, failing to understand how variations in combinations of factors contribute to reading development and how this combination relates to intervention outcome. To fill this gap, this study explored links between 28 cognitive, environmental, and demographic variables related to dyslexia by employing a network analysis using a large clinical database of 1,257 elementary school children. We found two highly connected subparts in the network: one comprising reading fluency and accuracy measures, and one comprising intelligence-related measures. Interestingly, phoneme awareness was functionally related to the controlled and accurate processing of letter–speech sound mappings, whereas rapid automatized naming was more functionally related to the automated convergence of visual and speech information. We found evidence for the contribution of a variety of factors to (a)typical reading development, though associated with different aspects of the reading process. As such, our results contradict prevailing claims that dyslexia is caused by a single core deficit. This study shows how the network approach to psychopathology can be used to study complex interactions within the reading network and discusses future directions for more personalized interventions.
Non-pharmacological interventions preferably precede pharmacological interventions in acute agitation. Reviews of pharmacological interventions remain descriptive or compare only one compound with several other compounds. The goal of this study is to compute a systematic review and meta-analysis of the effect on restoring calmness after a pharmacological intervention, so a more precise recommendation is possible.
Method:
A search in Pubmed and Embase was done to isolate RCT’s considering pharmacological interventions in acute agitation. The outcome is reaching calmness within maximum of 2 h, assessed by the psychometric scales of PANSS-EC, CGI or ACES. Also the percentages of adverse effects was assessed.
Results:
Fifty-three papers were included for a systematic review and meta-analysis. Most frequent studied drug is olanzapine. Changes on PANNS-EC and ACES at 2 h showed the strongest changes for haloperidol plus promethazine, risperidon, olanzapine, droperidol and aripiprazole. However, incomplete data showed that the effect of risperidon is overestimated. Adverse effects are most prominent for haloperidol and haloperidol plus lorazepam.
Conclusion:
Olanzapine, haloperidol plus promethazine or droperidol are most effective and safe for use as rapid tranquilisation. Midazolam sedates most quickly. But due to increased saturation problems, midazolam is restricted to use within an emergency department of a general hospital.
The stable isotope composition of planktonic foraminifera correlates with evidence for pulses of terrigenous sediment in a sediment core from the upper continental slope off northeastern Brazil. Stable oxygen isotope records of the planktonic foraminiferal species Globigerinoides sacculiferand Globigerinoides ruber(pink) reveal sub-Milankovitch changes in sea-surface hydrography during the last 85,000 yr. Warming of the surface water coincided with terrigenous sedimentation pulses that are inferred from high XRF intensities of Ti and Fe, and which suggest humid conditions in northeast Brazil. These tropical signals correlate with climatic oscillations recorded in Greenland ice cores (Dansgaard-Oeschger cycles) and in sediment cores from the North Atlantic (Heinrich events). Trade winds may have caused changes in the North Brazil Current that altered heat and salt flux into the North Atlantic, thus affecting the growth and decay of the large glacial ice sheets.
Partly laminated sediments were sampled from the brine-filled, anoxic Shaban Deep basin in the northern Red Sea. At about 4200 cal yr BP more than two millennia of anoxic sedimentation is replaced by a sub-oxic facies strongly suggesting the episodic absence of the brine. At the same time stable oxygen isotopes from surface dwelling foraminifera show a sharp increase (within less than 100 yr) pointing to a strong positive salinity anomaly at the sea surface. This major evaporation event significantly enhanced the renewal of deep water and the subsequent ventilation of the small Shaban Deep basin. The timing and strength of the reconstructed environmental changes around 4200 cal yr BP suggest that this event is the regional expression of a major drought event, which is widely observed in the neighboring regions, and which strongly affected Middle East agricultural civilizations.
Particle size reduction is a primary means of improving efficiency in herbivores. The mode of food particle size reduction is one of the main differences between herbivorous birds (gizzard) and mammals (teeth). For a quantitative comparison of the efficiency of food comminution, we investigated mean fecal particle sizes (MPS) in 14 herbivorous bird species and compared these with a data set of 111 non-ruminant herbivorous mammal species. In general MPS increased with body mass, but there was no significant difference between birds and mammals, suggesting a comparable efficiency of food processing by gizzards and chewing teeth. The results lead to the intriguing question of why gizzard systems have evolved comparatively rarely among amniote herbivores. Advantages linked to one of the two food comminution systems must, however, be sought in different effects other than size reduction itself. In paleoecological scenarios, the evolution of “dental batteries,” for example in ornithopod dinosaurs, should be considered an advantage compared to absence of mastication, but not compared to gizzard-based herbivory.
We report on progress with PL imaging applications in silicon solar cell production, specifically focusing on the characterization of silicon bricks prior to wafer cutting. Silicon bricks represent an ideal opportunity to characterize and quantify the electronic material quality at an early stage of the PV value chain. Quantitative data on bulk lifetime can be obtained on bricks without any specific sample preparation, unlike unprocessed wafers. Spatially resolved bulk lifetime, interstitial iron concentration, and defect density measurements are demonstrated on bricks from different manufacturers including both high performance multicrystalline and older generation multicrystalline bricks. We find significant variability in bulk lifetime and iron concentration across the samples which is not related to its date of manufacture. However we do see a qualitative reduction in crystallographic defects in the newer high performance multicrystalline bricks. Data is parameterized in different ways to suggest possible paths to better predict solar cell efficiencies from an early stage of inspection.
Brick level PL measurements were previously performed using a conventional area scanning PL imaging system, which is associated with light spreading artefacts of weakly absorbed light. To overcome these artefacts, a new line scanning photoluminescence imaging system is used. We show a reduction in contrast smearing between high- and low lifetime regions in the new setup leading to image quality suitable for defect detection and quantitative measurements without deconvolution correction.
The island of Cyprus was a major producer of copper and stood at the heart of east Mediterranean trade networks during the Late Bronze Age. It may also have been the source of the Red Lustrous Wheelmade Ware that has been found in mortuary contexts in Egypt and the Levant, and in Hittite temple assemblages in Anatolia. Neutron Activation Analysis (NAA) has enabled the source area of this special ceramic to be located in a geologically highly localised and geochemically distinctive area of western Cyprus. This discovery offers a new perspective on the spatial organisation of Cypriot economies in the production and exchange of elite goods around the eastern Mediterranean at this time.
German-language thinkers such as Kant, Marx, Nietzsche, and Freud are central to modernity. Yet their reception in the English-speaking world has largely depended on translations, a situation that has often hampered full engagement with the rhetorical and philosophical complexity of the German history of ideas. The present volume, the first of its kind, is a response to this situation. After an introduction charting the remarkable flowering of German-language thought since the eighteenth century, it offers extracts -- in the original German -- from sixteen major philosophical texts, with extensive introductions and annotations in English. All extracts are carefully chosen to introduce the individual thinkers while allowing the reader to pursue broader themes such as the fate of reason or the history of modern selfhood. The book offers students and scholars of German a complement to linguistic, historical, and literary study by giving them access to the wealth of German-language philosophy. It represents a new way into the work of a succession of thinkers who have defined modern philosophy and thus remain of crucial relevance today. The philosophers: Immanuel Kant, G. W. F. Hegel, Ludwig Feuerbach, Karl Marx, Arthur Schopenhauer, Friedrich Nietzsche, Sigmund Freud, Martin Heidegger, Walter Benjamin, Georg Lukács, Max Horkheimer and Theodor Adorno, Jürgen Habermas. Henk de Berg is Professor of German at the University of Sheffield. Duncan Large is Professor of German at Swansea University.
Axer H, Bernstein H-G, Keiner S, Heronimus P, Sauer H, Witte OW, Bogerts B, Bär K-J. Increased neuronal cell number in the dorsal motor nucleus of the vagus in schizophrenia.
Objective:
Recently, a reduction in efferent vagal regulation has been found in schizophrenic patients.
Methods:
Therefore, the brainstems of nine schizophrenic patients and nine normal controls were stereologically analysed. The number of neurons using the optical fractionator method and nuclear volumes applying the Cavalieri principle was estimated in Nissl stained sections of the dorsal motor nucleus of the vagus (DMNV) and the hypoglossal nucleus.
Results:
The neurons in the right DMNV were significantly increased in the schizophrenic group compared to normal controls (p = 0.047), while the volumes of the DMNV did not differ. In contrast, no such differences were found in the hypoglossal nucleus.
Conclusion:
Although this pilot study is limited by its small sample size, the analysis of the solitarius–ambiguus–vagus system in schizophrenic patients is an interesting target in schizophrenia research. The most reasonable background for increased neuron numbers in the DMNV could be a system-specific neurodevelopmental disturbance in schizophrenia.
Of the two authors of Dialektik der Aufklärung, Theodor W. Adorno is by far the more influential philosopher. Born in Frankfurt in 1903, he lived his first eleven years in the same street on which Arthur Schopenhauer had once resided. His father, Oscar Wiesengrund, owned a successful wine business; his mother, Maria Calvelli-Adorno della Piana, had been an opera singer. It was only when Adorno emigrated to America, in 1938, that he replaced the patronymic Wiesengrund with the less German-sounding surname taken from his mother. Maria's unmarried sister, Agathe, a well-known pianist, also lived with the family, and within this environment Adorno developed a passion for music. Indeed, for a while he even considered becoming a professional composer: in 1925, after having completed a PhD in philosophy at the tender age of twenty, he moved to Vienna to study composition with Alban Berg, who, like his master Arnold Schönberg, was among the most famous avant-garde composers of the day. But Adorno, though not without musical talent, lacked genuine creativity, and he soon returned to Frankfurt — and to philosophy. In this field, he possessed an originality and mental penetration matched by few. He never lost his interest in music, however, and a significant part of his oeuvre is devoted to the topic.
The Nazi ascent to power in 1933 robbed the Jewish philosopher of his teaching position at the University of Frankfurt and forced him into exile in Britain. He stayed there for the next five years — not, as he had hoped, as a university lecturer, but as a PhD student at Merton College, Oxford. His subsequent emigration to America was facilitated by Max Horkheimer.
The year 1788 stands out in the history of German philosophy for being the year in which Kant's Kritik der praktischen Vernunft was published, in Riga, and Arthur Schopenhauer was born, down the Baltic coast in Danzig (now Gdańsk, Poland), on 22 February. This contingent conjunction of the two philosophers’ lives was a happy coincidence, since Schopenhauer would in due course become one of Kant's most devoted followers (as well as one of his most stringent critics). Their lives were markedly different, though, and can perhaps be taken as symptomatic of the larger differences between the Enlightenment and the Romantic age that followed it: whereas Kant's life was well-regulated, governed by duty and rational insight, and devoted to the pursuit of knowledge, Schopenhauer's was, at least for its first forty-five years, restless, effervescent, and diverse.
Schopenhauer's father, Heinrich, was a merchant and shipowner who moved the family to Hamburg for business reasons in 1793, when Prussia annexed the free city of Danzig. This was but the first major upheaval in the life of the philosopher, who continued to travel extensively in his childhood and youth, picking up fluent competence in foreign languages as he went, and gaining the education and experience required to follow in his father's footsteps. Arthur spent two years in Le Havre (1797–99), for example, and even enrolled for three months at a boarding school in London (1803).
Friedrich Wilhelm Nietzsche was born in the village of Röcken, Saxony, on 15 October 1844. His father and both grandfathers were Protestant clergymen, so the family naturally expected him to follow in this tradition when, after attending primary school in Naumburg, in 1858 he took up a place at the prestigious boarding school of Schulpforta nearby. Here, he excelled at the classics, which he went on to study at the universities of Bonn (1864) and Leipzig (1865–69), by which stage he had abandoned his religious faith. As a student he fell under the influence of the philosophy of Arthur Schopenhauer (after discovering Die Welt als Wille und Vorstellung in 1865) and the ideas, music, and personality of the composer Richard Wagner, whom he first met in 1868. He would wrestle with their work for the remainder of his career.
Nietzsche's academic distinction was such that, on the recommendation of his supervisor Friedrich Wilhelm Ritschl, he was appointed Professor of Classical Philology at the University of Basel at the precocious age of 24 without even having completed his doctorate. He took up the post in the autumn of 1869. Upon his appointment, he renounced his Prussian citizenship, but he was nevertheless patriotic enough to volunteer for the Prussian army the following year, so as to fight in the Franco-Prussian War. His extremely poor eyesight confined him to service as a medical orderly. After a few weeks, he contracted diphtheria and dysentery at the front and was discharged. Poor health of one kind or another, especially migraine attacks, would dog him for the rest of his life.
Heidegger polarizes opinion. To some, he is the most important philosopher of the twentieth century; to others, he is little more than a mystifying word-spinner. The perplexingly difficult nature of his work derives to a significant extent from his exploitation of the resources of the German language, so — even more than with most other philosophers — there is a clear advantage in reading him in the original rather than in translation. In the immediate postwar period, the vogue for Existentialism favored Jean-Paul Sartre (whose early philosophy was largely based, as Hubert L. Dreyfus once put it, on “a brilliant misunderstanding” of Heidegger's Sein und Zeit), but the German thinker has since eclipsed him. However, while Heidegger's seriousness of philosophical purpose is beyond doubt, and while his critique of metaphysical abstractions often reads as yet another metaphysical abstraction — in the words of Malcolm Bowie, “a motor-cycle does appear in Being and Time, but such intrusions are rare” — his reputation is tarnished by some very concrete real-world decisions he took during a key period in his life.
Martin Heidegger was born in the Swabian town of Meßkirch, in southwestern Germany, on 26 September 1889. Initially destined for the priesthood, he studied theology and philosophy in Konstanz and Freiburg, flirting with the idea of a Jesuit novitiate. In the summer of 1911, he abandoned his plans to become a priest, dropped theology, and continued with philosophy alone, combining a study of the leading phenomenological and hermeneutic thinkers — Edmund Husserl (1859–1938) and Wilhelm Dilthey (1833–1911) — with a focus on Scholasticism (medieval Roman Catholic thought).