Yiyang Dahegu rice (YyDHG) is an important agricultural specialty of Yiyang County, Jiangxi Province, and it is also a significant component of the local cultural and economic development. In this experiment, 89 samples of Dahegu rice (DHG) were collected from Jiangxi Province, including 52 samples of YyDHG and 37 samples of DHG from other regions within Jiangxi Province (oDHG). Comprehensive analysis was conducted using polyacrylamide gel electrophoresis, field phenotypic observation, population structure analysis and quality analysis. The results of variety identification indicated that the 89 samples actually comprised 52 distinct varieties, including 19 varieties of YyDHG. Population analysis has revealed rich genetic diversity among DHG varieties within Jiangxi Province, yet no significant subpopulation differentiation was observed between YyDHG and oDHG. Quality experiments demonstrated that YyDHG exhibits significant differences in appearance quality from oDHG, but no notable differences in milling quality or cooked taste and flavour. This suggests that the competitiveness of YyDHG in the market may not entirely depend on its unique quality characteristics, but rather more on its cultural value and brand effect. This experiment conducted a comprehensive analysis of the variety characteristics, genetic diversity and quality traits of YyDHG. Not only does it provide a scientific basis for the breeding and germplasm resource conservation of YyDHG, but it also holds positive implications for promoting the development of its industry.

Overnutrition during before and pregnancy can cause maternal obesity and raise the risk of maternal metabolic diseases during pregnancy, and in offspring. Lentinus edodes may prevent or reduce obesity. This study aimed to to assess Lentinus edodes fermented products effects on insulin sensitivity, glucose and lipid metabolism in maternal and offspring, and explore its action mechanism. A model of overnutrition during pregnancy and lactation was developed using a 60 % kcal high-fat diet in C57BL6/J female mice. Fermented Lentinus edodes (FLE) was added to the diet at concentrations of 1 %, 3 %, and 5 %. The results demonstrated that FLE to the gestation diet significantly reduced serum insulin levels and homeostatic model assessment for insulin resistance (HOMA-IR) in pregnant mice. FLE can regulate maternal lipid metabolism and reduce fat deposition. Meanwhile, the hepatic phosphoinositide-3-kinase-protein kinase (PI3K/AKT) signaling pathway was significantly activated in the maternal mice. There is a significant negative correlation between maternal FLE supplementation doses and offspring body fat percentage and visceral fat content. Furthermore, FLE supplementation significantly increased offspring weaning litter weight, significantly reduced fasting glucose level, serum insulin level, HOMA-IR and serum glucose level, significantly activated liver PI3K/AKT signaling pathway in offspring, and upregulated the expression of liver lipolytic genes adipose triglyceride lipase, hormone-sensitive lipase and carnitine palmitoyltransferase 1 mRNA. Overall, FLE supplementation can regulate maternal lipid metabolism and reduce fat deposition during pregnancy and lactation, and it may improve insulin sensitivity in pregnant mothers and offspring at weaning through activation of the PI3K/AKT signaling pathway.

The whitefly Bemisia tabaci (Hemiptera: Aleyrodidae) is economically one of the most threatening pests in tomato cultivation, which not only causes direct damage but also transmits many viruses. Breeding whitefly-resistant tomato varieties is a promising and environmentally friendly method to control whitefly populations in the field. Accumulating evidence from tomato and other model systems demonstrates that flavonoids contribute to plant resistance to herbivorous insects. Previously, we found that high flavonoid-producing tomato line deterred whitefly oviposition and settling behaviours, and was more resistant to whiteflies compared to the near-isogenic low flavonoid-producing tomato line. The objective of the current work is to describe in detail different aspects of the interaction between the whitefly and two tomato lines, including biochemical processes involved. Electrical penetration graph recordings showed that high flavonoid-producing tomato reduced whitefly probing and phloem-feeding efficiency. We also studied constitutive and induced plant defence responses and found that whitefly induced stronger reactive oxygen species accumulation through NADPH oxidase in high flavonoid-producing tomato than in low flavonoid-producing tomato. Moreover, whitefly feeding induced the expression of callose synthase genes and resulted in callose deposition in the sieve elements in high flavonoid-producing tomato but not in low flavonoid-producing tomato. As a consequence, whitefly feeding on high flavonoid-producing tomato significantly decreased uptake of phloem and reduced its performance when compared to low flavonoid-producing tomato. These results indicate that high flavonoid-producing tomato provides phloem-based resistance against whitefly infestation and that the breeding of such resistance in new varieties could enhance whitefly management.

An actively controllable cascaded proton acceleration driven by a separate 0.8 picosecond (ps) laser is demonstrated in proof-of-principle experiments. MeV protons, initially driven by a femtosecond laser, are further accelerated and focused into a dot structure by an electromagnetic pulse (EMP) on the solenoid, which can be tuned into a ring structure by increasing the ps laser energy. An electrodynamics model is carried out to explain the experimental results and show that the dot-structured proton beam is formed when the outer part of the incident proton beam is optimally focused by the EMP force on the solenoid; otherwise, it is overfocused into a ring structure by a larger EMP. Such a separately controlled mechanism allows precise tuning of the proton beam structures for various applications, such as edge-enhanced proton radiography, proton therapy and pre-injection in traditional accelerators.

Noise source identification has been a long-standing challenge for decades. Although it is known that sound sources are closely related to flow structures, the underlying physical mechanisms remain controversial. This study develops a sound source identification method based on longitudinal and transverse process decomposition (LTD). Large-eddy simulations were performed on the flow around a cylinder at a Reynolds number of 3900. Using the new LTD method, sound sources in the cylinder flow were identified, and the mechanisms linking flow structures with noise generation were discussed in detail. Identifying the physical sound sources from two levels, low-order theory and high-order theory, the physical mechanism of wall sound sources was also analysed. Results indicate that the sound sources in the flow field mainly come from the leading edge, shear layer and wake region of the cylinder. The high-order theory reveals that sound sources are correlated with the spatio-temporal evolution of enstrophy, vortex stretching and surface deformation processes, this reflecting the coupling between transversal and longitudinal flow fields. The boundary thermodynamic flux and boundary dilatation flux distribution of the cylinder were analysed. Results indicate that the wall sound sources mainly come from the separation point and have a disorderly distribution on the leeward side of the cylinder, which is the main region where longitudinal variables enter the fluid from the wall surface, and the wall sound source is related to the boundary enstrophy flux.

In response to the auxiliary requirements for the treatment and prevention of lumbar diseases, based on the biomechanical characteristics of the human waist, a novel unpowered rigid-flexible coupling waist exoskeleton with multiple degrees of freedom and its human-exoskeleton parallel wearable equivalent research prototype are proposed, further focusing on the encompassing kinematic compatibility and dynamic load-bearing effectiveness of the biomimetic coordination, an in-depth analysis is performed on the multi-body dynamic dimensional synthesis and its methodological research. Initially, based on the rigid-flexible coupling characteristics and experimental biomechanical data of the lumbar region in the sagittal plane, an accurate multi-body system dynamics model of the research prototype, which incorporates the rigid-flexible coupling characteristics, is systematically constructed. Subsequently, to effectively quantify the biomimetic coordination of the exoskeleton, a novel comprehensive optimization index, termed biomimetic load-bearing comfort, is proposed. Finally, by utilizing this index, the exoskeleton is optimized in dimension by employing a thorough combination of multi-dimensional spatial search algorithm and compression factor particle swarm algorithm. The simulation results validate the correctness and effectiveness of both the dynamic dimensional synthesis and its methodology. Furthermore, the study also reveals that the optimized exoskeleton’s passive working mode showcases favorable biomimetic coordination. These results are crucial for progressing the research on the biomimetic load-bearing capacities of other exoskeletons.

Developing a consistent near-wall turbulence model remains an unsolved problem. The machine learning method has the potential to become the workhorse for turbulence modelling. However, the learned model suffers from limited generalisability, especially for flows without similarity laws (e.g. separated flows). In this work, we propose a knowledge-integrated additive (KIA) learning approach for learning wall models in large-eddy simulations. The proposed approach integrates the knowledge in the simplified thin-boundary-layer equation with a data-driven forcing term for the non-equilibrium effects induced by pressure gradients and flow separations. The capability learned from each flow dataset is encapsulated using basis functions with the corresponding weights approximated using neural networks. The fusion of capabilities learned from various datasets is enabled using a distance function, in a way that the learned capability is preserved and the generalisability to other cases is allowed. The additive learning capability is demonstrated via training the model sequentially using the data of the flow with pressure gradient but no separation, and the separated flow data. The capability of the learned model to preserve previously learned capabilities is tested using turbulent channel flow cases. The periodic hill and the 2-D Gaussian bump cases showcase the generalisability of the model to flows with different surface curvatures and different Reynolds numbers. Good agreements with the references are obtained for all the test cases.

Nonlinear optical gain modulation (NOGM) is an effective approach for generating highly coherent femtosecond Raman pulses. In a typical NOGM system, the pump pulse energy boosting unit and nonlinear frequency conversion unit are separated, which poses a difficulty in generating Raman solitons with pulse energy over the μJ level. Here, we demonstrate an integrated ultrafast ytterbium-Raman fiber amplifier, which accomplishes pump pulse amplification and Raman pulse conversion simultaneously in ytterbium-doped fiber (YDF). The integrated ytterbium-Raman fiber amplifier could generate approximately 1 μJ 1121 nm Raman pulses with a pulse duration of 589 fs under a conversion efficiency of 69.9%. The result represents the highest pulse energy experimentally recorded in NOGM systems. Simulation further reveals that YDF gain could promote Raman conversion efficiency and reduce nonlinear chirp accumulation, which leads to improved performance of generated Raman pulses. Meanwhile, the feasibility of generating 10 μJ level Raman pulses using such a hybrid gain setup was also confirmed numerically.

We introduce the exponentially preferential recursive tree and study some properties related to the degree profile of nodes in the tree. The definition of the tree involves a radix $a\gt 0$. In a tree of size $n$ (nodes), the nodes are labeled with the numbers $1,2, \ldots ,n$. The node labeled $i$ attracts the future entrant $n+1$ with probability proportional to $a^i$.

We dedicate an early section for algorithms to generate and visualize the trees in different regimes. We study the asymptotic distribution of the outdegree of node $i$, as $n\to \infty$, and find three regimes according to whether $0 \lt a \lt 1$ (subcritical regime), $a=1$ (critical regime), or $a\gt 1$ (supercritical regime). Within any regime, there are also phases depending on a delicate interplay between $i$ and $n$, ramifying the asymptotic distribution within the regime into “early,” “intermediate” and “late” phases. In certain phases of certain regimes, we find asymptotic Gaussian laws. In certain phases of some other regimes, small oscillations in the asymototic laws are detected by the Poisson approximation techniques.

Raman fiber lasers, known for their capacity to provide both high-power and precise wavelength emissions, are gaining attraction across a spectrum of applications, including fiber optic communications, sensing, spectroscopy and imaging. However, the scalability of Raman laser power is impeded by the constraints of pump brightness and the deleterious effects of second-order Raman scattering. In this research, we have undertaken a comprehensive experimental and simulation-based investigation into the impact of pump brightness on the output characteristics within an amplifier framework. Our innovative approach integrates high-brightness pumping with multi-mode graded-index fibers. Notably, we have pioneered the introduction of multi-wavelength seed light to facilitate four-wave mixing, thereby effectively mitigating higher-order Raman scattering. This novel strategy has culminated in the achievement of a 4 kW Raman laser output in an all-fiber configuration, representing the highest output power reported so far.

This study examined global trends in influenza-associated lower respiratory infections (LRIs) deaths from 1990 to 2019 using data from the GBD 2019. The annual percentage change (APC) and average annual percentage change (AAPC) were used to analyze age-standardized death rates (ASDR). Globally, the ASDR of influenza-associated LRIs was 3.29/100,000 in 2019, which was higher in the African region (6.57/100,000) and among adults aged 70 years and older (29.88/100,000). The ASDR of influenza-associated LRIs decreased significantly from 1990 to 2019 (AAPC = −1.88%, P < 0.05). However, it was significantly increased among adults aged 70 years and older during 2017–2019 (APC = 2.31%, P < 0.05), especially in Western Pacific Region and South-East Asia Regions. The ratio of death rates between adults aged 70 years and older and children aged under 5 years increased globally from 1.63 in 1990 to 5.34 in 2019, and the Western Pacific Region experienced the most substantial increase, with the ratio soaring from 1.83 in 1990 to 12.98 in 2019. Despite a decline in the global ASDR of influenza-associated LRIs, it continues to impose a significant burden, particularly in the African, Western Pacific regions and among the elderly population.

This study investigates the effects of fat emulsion-based early parenteral nutrition in patients following hemihepatectomy, addressing a critical gap in clinical knowledge regarding parenteral nutrition after hemihepatectomy. We retrospectively analysed clinical data from 274 patients who received non-fat emulsion-based parenteral nutrition (non-fatty nutrition group) and 297 patients who received fat emulsion-based parenteral nutrition (fatty nutrition group) after hemihepatectomy. Fat emulsion-based early parenteral nutrition significantly reduced levels of post-operative aspartate aminotransferase, total bilirubin and direct bilirubin, while minor decreases in red blood cell and platelet counts were observed in the fatty nutrition group. Importantly, fat emulsion-based early parenteral nutrition shortened lengths of post-operative hospital stay and fasting duration, but did not affect the incidence of short-term post-operative complications. Subgroup analyses revealed that the supplement of n-3 fish oil emulsions was significantly associated with a reduced inflammatory response and risk of post-operative infections. These findings indicate that fat emulsion-based early parenteral nutrition enhances short-term post-operative recovery in patients undergoing hemihepatectomy.

This paper provides an overview of the current status of ultrafast and ultra-intense lasers with peak powers exceeding 100 TW and examines the research activities in high-energy-density physics within China. Currently, 10 high-intensity lasers with powers over 100 TW are operational, and about 10 additional lasers are being constructed at various institutes and universities. These facilities operate either independently or are combined with one another, thereby offering substantial support for both Chinese and international research and development efforts in high-energy-density physics.

The betatron radiation source features a micrometer-scale source size, a femtosecond-scale pulse duration, milliradian-level divergence angles and a broad spectrum exceeding tens of keV. It is conducive to the high-contrast imaging of minute structures and for investigating interdisciplinary ultrafast processes. In this study, we present a betatron X-ray source derived from a high-charge, high-energy electron beam through a laser wakefield accelerator driven by the 1 PW/0.1 Hz laser system at the Shanghai Superintense Ultrafast Laser Facility (SULF). The critical energy of the betatron X-ray source is 22 ± 5 keV. The maximum X-ray flux reaches up to 4 × 109 photons for each shot in the spectral range of 5–30 keV. Correspondingly, the experiment demonstrates a peak brightness of 1.0 × 1023 photons·s−1·mm−2·mrad−2·0.1%BW−1, comparable to those demonstrated by third-generation synchrotron light sources. In addition, the imaging capability of the betatron X-ray source is validated. This study lays the foundation for future imaging applications.

This paper investigates the long-run nexus between wealth inequality and aggregate output using a DSGE model in which wealth inequality endogenously affects individual entrepreneurship incentives, thereby influencing aggregate output. Our model passes the indirect inference test against the UK data from 1870 to 2015. We find that shocks to aggregate TFP, entrepreneurial barriers, government grant support and general government spending played significant roles in shaping historical inequality dynamics in the UK. Directly removing entrepreneurial barriers or indirectly providing government grant support to the private sector such as through inclusive loan subsidies are effective means of reducing inequality and stimulating output growth.

The ubiquitous marine radiocarbon reservoir effect (MRE) constrains the construction of reliable chronologies for marine sediments and the further comparison of paleoclimate records. Different reference values were suggested from various archives. However, it remains unclear how climate and MREs interact. Here we studied two pre-bomb corals from the Hainan Island and Xisha Island in the northern South China Sea (SCS), to examine the relationship between MRE and regional climate change. We find that the MRE from east of Hainan Island is mainly modulated by the Southern Asian Summer Monsoon-induced precipitation (with 11.4% contributed to seawater), rather than wind induced upwelling. In contrast, in the relatively open seawater of Xisha Island, the MRE is dominated by the East Asian Winter Monsoon, with relatively more negative (lower) ΔR values associated with high wind speeds, implying horizontal transport of seawater. The average SCS ΔR value relative to the Marine20 curve is –161±39 14C years. Our finding highlights the essential role of monsoon in regulating the MRE in the northern SCS, in particularly the tight bond between east Asian winter monsoon and regional MRE.

Multiple osteoarticular tuberculosis (MOT) represents an uncommon yet severe form of tuberculosis, characterized by a lack of systematic analysis and comprehension. Our objective was to delineate MOT’s epidemiological characteristics and establish a scientific foundation for prevention and treatment. We conducted searches across eight databases to identify relevant articles. Pearson’s chi-square test (Fisher’s exact test) and Bonferroni method were employed to assess osteoarticular involvement among patients of varying age and gender (α = 0.05). The study comprised 98 articles, encompassing 151 cases from 22 countries, with China and India collectively contributing 67.55% of cases. MOT predominantly affected individuals aged 0–30 years (58.94%). Pulmonary tuberculosis was evident in 16.55% of cases, with spinal involvement prevalent (57.62%). Significant differences were noted in trunk, spine, thoracic, and lumbar vertebrae involvement, as well as type I lesions across age groups, increasing with age. Moreover, significant differences were observed in upper limb bone involvement and type II lesions across age groups, decreasing with age. Gender differences were not significant. MOT primarily manifests in China and India, predominantly among younger individuals, indicating age-related variations in osteoarticular involvement. Enhanced clinical awareness is crucial for accurate MOT diagnosis, mitigating missed diagnoses and misdiagnoses.