Spanwise wall oscillation (SWO) of turbulent boundary layers (TBLs) is investigated via direct numerical simulations (DNS) over an extended actuation region (momentum Reynolds number
$344\lt Re_\theta \lt 2340$) with oscillation periods up to
$T_{\textit{sc}}^+=600$, scaled by the uncontrolled friction velocity
$u_{\tau 0}$ at the onset of SWO (i.e.
$ \textit{Re}_\theta =344$). For low periods (
$T_{\textit{sc}}^+\lt 200$), drag reduction (
$ \textit{DR} $) decreases with increasing
$ \textit{Re}_\theta$, consistent with conventional inner-scaled control strategies targeting near-wall turbulence. In sharp contrast, for large periods (
$T_{\textit{sc}}^+\gt 200$),
$ \textit{DR} $ increases with
$ \textit{Re}_\theta$. For example, at
$T_{\textit{sc}}^+=600$,
$ \textit{DR} $ rises from 1.3 % at
$ \textit{Re}_\theta =713$ to 7.0 % at
$ \textit{Re}_\theta =2340$. This unexpected growth is partly explained by the streamwise evolution of the effective oscillation parameter: as a TBL develops,
$u_{\tau 0}$ decreases downstream, reducing the local-scaled period
$T^+$ and thereby enhancing suppression of near-wall turbulence. Interestingly, if the results are compared at approximately fixed
$T^+$, then
$ \textit{DR} $ for
$T^+\gt 350$ still exhibits a weak positive dependence on
$ \textit{Re}_\theta$, consistent with recent experiments by Marusic et al. (2021, Nat. Commun., vol. 12, 5805). We further develop a new analytical relationship that links
$ \textit{DR} $ to the upward shift of mean velocity in the wake region. Unlike previous formulations, the relationship avoids logarithmic-region fitting and does not rely on an invariant Kármán constant under SWO, while maintaining good agreement with DNS data. Flow diagnostics – including Reynolds stresses, skin-friction decomposition, and energy spectra – demonstrate that the observed variation of
$ \textit{DR} $ with Reynolds number (
$ \textit{Re}$) arises from period-dependent modulation of near-wall turbulence. Overall, these findings challenge the conventional view that
$ \textit{DR} $ inevitably deteriorates with
$ \textit{Re}$, and demonstrate that out-scaled actuation can instead enhance
$ \textit{DR} $ performance – offering new physical insights for high-
$ \textit{Re}$ control strategies.