To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
The present study examined the association of body mass index (BMI), screen and sleep time, physical fitness and eating behaviour with Mediterranean diet (MD) adherence in a sample of pre-schoolers from Granada, Spain.
Design:
A cross-sectional, non-randomised design was employed. A multilinear regression model with backward elimination was used for analysis.
Setting:
Variables included age, BMI, screen time, hours of nightly sleep, physical fitness, food approach and food avoidance. The developed model met assumptions of multiple regression in terms of linearity, homoscedasticity, normality, independence and non-multicollinearity.
Participants:
Data were collected from 653 of the 2250 three-to-six-year-old children attending the 18 schools invited to take part in the present study.
Results:
Better sleep time and lower screen time and food avoidance were found to be predictive of MD adherence. These variables explained 15% of the variance in pre-schoolers MD adherence.
Conclusions:
The present study suggests that sleep and screen time and food avoidance are important components to consider when targeting improvements in MD adherence in pre-schoolers. Future research should explore the way in which parental health behaviours influence their children’s health habits in order to better understand outcomes.
The role of healthcare provider ownership in shaping health system performance remains contested. An umbrella review was conducted to synthesise evidence on the relationship between healthcare provider ownership and performance in high-income countries. Systematic reviews were included that examined performance of healthcare providers based on ownership status. Searches yielded 1,862 results, with 31 systematic reviews meeting the inclusion criteria, and one further systematic review identified through grey literature searches. Following the exclusion of 10 reviews classified as low-quality and two previous umbrella reviews both published in 2014, 20 reviews were eligible for data extraction and synthesis. Inconsistent evidence was found across reviews between healthcare provider ownership and several performance indicators including health outcomes, technical efficiency, and patient satisfaction. Private hospitals tend to serve wealthier patients, select less complex or costly patients, and charge higher payments for care than public comparators. Private for-profit (FP) providers of hospital and long-term care generally had poorer workforce outcomes than private not-for-profit or public providers, including reduced staffing levels, higher workloads, and lower job satisfaction. Private PF hospitals and nursing homes had improved financial performance based on revenues or profit margins. Our findings underscore the need for nuanced regulatory responses to the expansion of private FP provision within publicly funded systems.
This study aims to examine the awareness, attitudes, and acceptability of medical aid in dying (MAiD) among healthcare professionals in Pakistan, a predominantly Muslim country where cultural and religious values heavily influence medical ethics and end-of-life decisions.
Methods
A cross-sectional survey was conducted online among 70 healthcare professionals, including physicians, nurses, and allied health workers in Pakistan. Data were collected via a structured, self-administered online questionnaire assessing knowledge, attitudes, and willingness to participate in MAiD-related actions. Descriptive and correlational analyses were conducted to identify patterns and associations.
Results
Participants demonstrated moderate knowledge about MAiD (M = 17.13, SD = 3.42) and moderate support for its legalization (M = 18.89, SD = 4.99). However, levels of negative attitudes (M = 32.21, SD = 6.11) and legal and ethical concerns (M = 24.73, SD = 3.66) were high. Behavioral willingness to engage in MAiD-related actions remained low (M = 2.42, SD = 3.38), with limited intent to assist (M = 0.39), refer (M = 0.64), or approve physician-assisted MAID (M = 0.81). A significant negative correlation emerged between knowledge and support for legalization (r = − .25, p = .037), while no significant associations were observed between knowledge and willingness to participate in MAiD. Gender and profession did not significantly influence attitudes or willingness.
Significance of results
While Pakistani healthcare professionals display a conceptual understanding of MAiD, their readiness to participate remains low, primarily due to ethical, legal, and religious concerns. These findings highlight the need for creating awareness regarding MAiD and for providing culturally sensitive education, structured training in palliative care, and the development of clear legal frameworks to guide end-of-life decision-making in Muslim-majority contexts.
To explore the experiences of military medical first responders managing mass casualty incidents (MCIs) during the ongoing conflict in Ukraine to identify key challenges and insights.
Methods
This qualitative study employed in-depth, semi-structured interviews with medical first responders who managed MCIs in Ukraine. Thematic analysis was leveraged by our research team to identify recurring themes and patterns within the interview data.
Results
Our results revealed crucial takeaways related to the (1) need for preparedness and training, (2) variability of triage, (3) importance of communication and teamwork, and (4) the resulting psychological strain.
Conclusions
These firsthand accounts offer valuable lessons for identifying challenges of first responders, developing areas of future research for MCI response strategies, and enhancing the readiness and well-being of medical first responders in current and future conflicts.
This study assessed iron-rich food consumption and its factors among children aged 6–23 months in South and Southeast Asia.
Design:
A cross-sectional study from the Standard Demographic and Health Survey (2015-2022).
Setting:
South and Southeast Asian countries.
Subjects:
Data collected from 95,515 children aged 6 to 23 months, including information from their parents or caregivers.
Results:
The overall proportion of children, aged 6 to 23 months, consuming iron-rich foods in the region was 29.87% (95% CI: 29.58, 30.16). Higher odds of iron-rich food consumption were observed among children aged 12–23 months (AOR = 3.59; 95% CI: 3.45–3.76), had history of exclusive breastfeeding (AOR = 1.17; 95% CI: 1.12–1.23), born to teenage motherhood (AOR = 1.09; 95% CI: 1.02–1.17), born in health institution (AOR = 1.10; 95% CI: 1.02–1.19), and had pregnant mother at the time of the survey (AOR = 1.60; 95% CI: 1.50–1.72). Children of birth order 2–4 (AOR = 1.26; 95% CI: 1.20–1.32) and 5+ (AOR = 1.29; 95% CI: 1.18–1.43), from female-headed households (AOR = 1.06; 95% CI: 1.01–1.12), and those with household mass media exposure (AOR = 1.27; 95% CI: 1.19–1.36) also had significantly higher odds of iron-rich food consumption. Additionally, higher odds ratios (AOR > 1) of iron-rich food consumption were observed in Cambodia, Bangladesh, Indonesia, Myanmar, Maldives, Philippines, Pakistan, and Timor-Leste.
Conclusion:
Across countries, only about 30% of children consumed iron-rich foods, with significant variation. Targeted public health efforts are essential to address maternal, child, and household factors that influence intake.
Patients with chronic liver disease (CLD) often experience hypozincemia. The clinical factors associated with hypozincemia have not been established. We investigated clinical factors that may be useful to predict hypozincemia in patients with CLD. The serum zinc levels CLD patients were measured; Study 1 investigated the predictive factors of hypozincemia, and Study 2 was performed to validate the factors identified in Study 1. Study 1 included 197 participants, of whom 28 and 106 had serum zinc levels <60 µg/dL and <80 µg/dL, respectively. A multivariate analysis revealed that serum zinc levels <60 µg/dL or <80 µg/dL were associated with the albumin–bilirubin (ALBI) score and serum albumin level. A receiver operating characteristic curve analysis revealed that the ALBI score ≥ −1.83 and the serum albumin level ≤3.3 g/dL were the cut-off values for a serum zinc level <60 µg/dL, whereas the ALBI score ≥ −2.44 and the serum albumin level ≤3.6 g/dL were the cut-off values for a serum zinc level <80 µg/dL. In Study 2 (n = 177), the diagnostic accuracy rates for serum zinc <60 µg/dL were 81.9% for the ALBI score and 75.1% for the serum albumin level, and those for serum zinc <80 µg/dL were 70.1% for both parameters. Together these findings indicate that the ALBI score may serve as a predictive factor of hypozincemia in CLD patients.
This study aimed to evaluate adult women’s cooking and food preparation skills and their nutrition literacy levels, and to examine the relationship between these two concepts.
Design:
Data were collected via face-to-face interviews using a personal information form, the Cooking and Food Skills Scale, and the Evaluation Instrument of Nutrition Literacy on Adults. Data were analyzed with SPSS, with p<0.05 considered significant.
Setting:
Female adults aged 20–64 who participated in family support courses in Tepebaşı, Eskişehir, Turkey.
Participants:
The study sample consisted of 330 female individuals between the ages of 20-64 who agreed to participate in the survey.
Results:
Nutrition literacy was generally adequate (91.8%), though gaps were identified in portion knowledge (54.2%) and food label reading (44.2%, borderline). Higher literacy levels were associated with being younger, more educated, and employed (p<0.05). Cooking and food preparation skills were higher among married women and those with children. Cooking frequency and enjoyment significantly influenced these skills (p<0.05). Those who cooked more often had higher scores in food label reading and basic math (p<0.001), and higher total scores (p=0.049). Participants who enjoyed cooking had better reading comprehension (p=0.030). A weak but significant correlation was found between food preparation skills and general nutrition knowledge, but no strong relationship was observed between overall cooking skills and total nutrition literacy.
Conclusion:
Although no strong link was found between nutrition literacy and cooking skills, these skills appear to support healthier eating behaviors. Promoting cooking and food preparation through nutrition education may help improve public health.
This study aimed to investigate 1) the longitudinal associations between food patterns and body weight in young adulthood, and 2) how food patterns of young adults relate to food consumption in early, middle and late childhood. The study sample includes 700 participants of the Québec Longitudinal Study of Child Development. During childhood, frequency of consumption of various foods was reported on ten occasions between 1.5 and 13 years. At age 22 years, food frequency questions (with quantities) were used to derive four food patterns (labeled healthy, beverage-rich, protein-rich, and high-energy-density) through exploratory factor analysis. Self-reported height and weight were collected at 22 and 23 years. Regression analyses were performed to assess associations between 1) food patterns and weight outcomes a year later (BMI, BMI change, and overweight status); 2) frequency of consumption of eight food groups in childhood and food patterns in adulthood. Dietary habits characterised by the consumption of vegetables, fruit, plant-based sources of protein and whole-grain cereal products were related to a lower risk of obesity a year later. Conversely, dietary habits characterised by a high consumption of energy-dense foods, of animal sources of proteins and, among women, of high quantities of liquids were associated with higher risk of excess weight a year later. Healthier food choices in childhood were associated with healthier food patterns in young adulthood. These findings reinforce the value of preventive dietary interventions in the early years to foster eating environments that favour healthy eating and healthy weights in adulthood.
Radiotherapy (RT) is a highly effective breast cancer treatment. However, RT can deliver radiation dose to the healthy tissues of the shoulder, increasing the potential for long-term shoulder morbidity. This study compared the dose delivered to key shoulder muscles between common RT techniques and patient positioning.
Methods:
The treatment plans of 54 patients were analysed, including those treated in the prone and supine positions. Eight shoulder muscles were contoured on each patient’s computer tomography scan. The following breast treatment techniques were analysed: hybrid-intensity-modulated RT (hybrid IMRT), wedged field, two partial arcs volumetric-modulated arc therapy (VMAT), hybrid VMAT, and 3-field supraclavicular technique. Moreover, the effect of patient positioning was also evaluated (supine versus prone). Muscle radiation exposure was compared for the mean dose and the percent muscle volume exposed to V15 Gy and V30 Gy.
Results:
The mean dose and exposed volume for the pectoralis major and pectoralis minor were similar between hybrid IMRT, wedged field, VMAT, and hybrid VMAT. VMAT and hybrid VMAT delivered a greater mean dose to most posterior shoulder muscles compared to hybrid IMRT, though overall exposure remained generally low for these muscles. The 3-field supraclavicular technique increased radiation exposure to all shoulder muscles, particularly to the pectoralis major, the pectoralis minor and the supraspinatus. Prone positioning significantly reduced V15 Gy and V30 Gy exposure for both anterior and posterior shoulder muscles.
Conclusion:
Shoulder muscle exposure was similar between hybrid IMRT, wedged field, VMAT and hybrid VMAT. The anterior shoulder muscles were consistently exposed to radiation with all RT techniques investigated in this study. In comparison, the 3-field supraclavicular technique substantially increased the radiation exposure to the posterior shoulder muscles. Lastly, delivering radiation in the prone position spared the anterior and posterior shoulder muscles. These findings inform treatment planning decisions aimed at mitigating the risk of long-term shoulder dysfunction.
The current study examined perceptions of and experiences with Flint Families Cook, a virtual cooking and nutrition program for youth and families.
Design:
Families were invited to participate in virtual focus groups after completing the five-week Flint Families Cook program. The research study was guided by Social Cognitive Theory. Researchers used thematic analysis to examine the transcribed focus groups, identify patterns across transcripts, and develop emerging themes.
Setting:
Families living in Flint and surrounding Genesee County, Michigan, USA engaged in virtual focus groups via Zoom.
Participants:
Youth (n=32; 59% female, 53% African American) and adult caregivers (n=31; 90% female, 39% African American) participated in focus groups between October 2020 and February 2022.
Results:
Five themes were generated from the focus group discussions: (i) general cooking challenges; (ii) class format; (iii) family support; (iv) provision of food; and (v) instruction and learning.
Conclusions:
In addition to perceived positive impacts on cooking skills and nutrition education, many participants shared that Flint Families Cook encouraged family cohesion and support. Most caregivers felt the program, which included instruction by a chef and dietitian as well as ingredient box delivery, had important impacts on emotional health of youth and family resilience. Flint Families Cook, and similar virtual scalable programs, could broadly reach children and families to support physical and psychosocial health, especially in low-resource communities where such interventions may be most beneficial.
End-of-life dreams and visions (ELDVs) and delirium frequently occur near death but differ in core features. Clinical differentiation becomes challenging when they co-occur. This case report illustrates the interplay between ELDVs and delirium, examines the limits of current diagnostic criteria in mixed cases, and outlines a nuanced approach to distinction.
Methods
We report the case of an elderly Brazilian woman with metastatic cancer who exhibited both ELDVs and delirium. Mental status was serially assessed using the Confusion Assessment Method (CAM). ELDV accounts were prospectively triangulated across patient, family, and clinician reports to enhance reliability and contextual understanding.
Results
The patient’s experiences showed ELDV hallmarks – vivid, realistic encounters with deceased relatives, biographical relevance, and preparatory themes – yet many were affectively distressing and occurred alongside fluctuating attention and consciousness consistent with delirium. CAM effectively identified delirium but could not, on its own, distinguish ELDVs within delirious states. When co-occurring, ELDVs often emerged during “windows of lucidity” marked by preserved autobiographical context, intact recall with subsequent coherent narration, and insight, despite intense emotional valence. Distress alone was not discriminatory, probably being shaped by psychosocial and cultural factors. These observations indicate the need to supplement CAM with qualitative and phenomenological criteria, including content, vividness, biographical meaning, insight, cultural fit, and acuity/recall.
Significance
To our knowledge, this is the first case to map evolving end-of-life mental status using serial CAM while prospectively documenting ELDVs via triangulated reports. The findings highlight the complexity of differentiating co-occurring ELDVs and delirium and challenge the sufficiency of CAM alone. An integrated approach – combining CAM screening with structured ELDV assessment – may prevent misclassification and support holistic, dignified palliative care. As a single case in an underexplored domain, these insights require confirmation in larger, prospective studies to assess generalizability.
This study aimed to evaluate the characteristics, difficulties, and outcomes of patients who underwent transcatheter ablation treatment due to arrhythmia with a diagnosis of CHD.
Methods:
A total of 166 patients (189 substrates) with CHD who underwent catheter ablation between November 2013 and 2023 were evaluated retrospectively. EnSite™ (St Jude Medical Inc., St Paul, MN, USA) was used in all patients.
Results:
The mean age was 14.8 ± 7.9 years (2.9–43 years). The most common CHD’s were Ebstein anomaly (n: 40), tetralogy of Fallot (n: 31), atrial septal defect (n: 25), ventricular septal defect (n: 22), great artery transposition (D/L TGA, n: 12), and complex CHD in single ventricle physiology (n: 9). The most common arrhythmia mechanisms were Wolf-Parkinson-White syndrome (WPW, n: 50), intraatrial reentrant tachycardia (IART, n: 39), typical atrioventricular nodal reentrant tachycardia (AVNRT, n: 37), and ventricular tachycardia-ventricular extrasystoles (VT/VES, n: 23). There was more than one arrhythmia in 23 patients and multiple manifest accessory pathways in 10 patients. The average procedure time was 174 ± 69.3 minutes, and the average fluoro time was 8.3 minutes. While successful ablation was performed in 176/189 (acute success 93.1%) substrates, the procedure was unsuccessful in five patients and suboptimal in eight patients. Recurrence was observed in 11 patients (6.4%) during a mean follow-up period of 49.2 ± 30.1 months. A second ablation was performed on 13 patients. Acute success was achieved in all except one patient. A total of 11 patients are being followed up with medical treatment.
Conclusion:
Despite the complex anatomy, age, operations, and limited vascular access possibilities in patients diagnosed with CHD, transcatheter ablation treatment with advances in electrophysiology, the introduction of different energy types, special ablation catheters, multipolar mapping catheters, and 3D nonfluoroscopic mapping systems seems to be a safe and effective option.
This study has investigated the relationship between the gut microbiota compotision and the growth performance in pigs from birth to the finishing stage, focusing on nutrient metabolism. Of 59 crossbred pigs [(Landrace × Large Yorkshire) × Duroc] from seven sows, individuals with high and low daily gain (DG) were assigned to high DG (HDG, n = 11) and low DG (LDG, n = 8) groups. Fecal samples collected at weaning (21 days), growing (95–106 days) and finishing (136–152 days) stages were analyzed for amino acids, short-chain fatty acids, and microbial composition using 16S rRNA sequencing. Although birth and weaning weights were similar in both groups, the HDG group had significantly higher weights in the growing and finishing stages (P < 0.01). The microbial composition of the LDG group revealed a higher abundance of f_Lachnospiraceae;__ at weaning (P < 0.05), whereas the HDG group contained higher abundance of g_Streptococcus and g_Prevotella 7 at the finishing stage (P < 0.05). Functional analysis revealed increased amino acid metabolism in the HDG group at the finishing stage (P < 0.05). During the growing stage, total free fecal amino acid content was low in the HDG group (P < 0.05); at weaning, levels of isobutyric and isovaleric acids, key amino acid fermentation products (P < 0.05, P < 0.01), were higher. These findings indicate growth stage-specific differences in the gut microbiota and metabolic profiles between groups with different growth performance, suggesting microbial and metabolic characteristics may influence growth performance.