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This paper is concerned with stochastic Schrödinger delay lattice systems with both locally Lipschitz drift and diffusion terms. Based on the uniform estimates and the equicontinuity of the segment of the solution in probability, we show the tightness of a family of probability distributions of the solution and its segment process, and hence the existence of invariant measures on $l^2\times L^2((-\rho,\,0);l^2)$ with $\rho >0$. We also establish a large deviation principle for the solutions with small noise by the weak convergence method.
There is significant evidence that an unhealthy diet greatly increases the risk of complications during pregnancy and predisposes offspring to metabolic dysfunction and obesity. While fat intake is typically associated with the onset of obesity and its comorbidities, there is increasing evidence linking sugar, particularly high fructose corn syrup, to the global rise in obesity rates. Furthermore, the detrimental effects of added sugar intake during pregnancy on mother and child have been clearly outlined. Guidelines advising pregnant women to avoid food and beverages with high fat and sugar have led to an increase in consumption of ‘diet’ or ‘light’ options. Examination of some human birth cohort studies shows that heavy consumption (at least one beverage a day) of non-nutritive sweetener (NNS) containing beverages has been associated with increased risk of preterm birth and increased weight/BMI in male offspring independent of maternal weight, which appears to be offset by breastfeeding for 6 months. Rodent models have shown that NNS exposure during pregnancy can impact maternal metabolic health, adipose tissue function, gut microbiome profiles and taste preference. However, the mechanisms underlying these effects are multifaceted and further research, particularly in a translational setting is required to fully understand the effects of NNS on maternal and infant health during pregnancy. Therefore, this review examines maternal sweetener intakes and their influence on fertility, maternal health outcomes and offspring outcomes in human cohort studies and rodent models.
Hypertrophic cardiomyopathy is the leading cause of sudden cardiac death among the paediatric population. The aim of this study is to investigate the prevalence and clinical significance of late gadolinium enhancement, as assessed by cardiac MRI, in paediatric hypertrophic cardiomyopathy.
Methods:
A systematic literature search was conducted in PubMed, SCOPUS, and Ovid SP to identify relevant studies. Pooled estimates with a 95% confidence interval were calculated using the random-effects generic inverse variance model. Statistical analysis was performed using Review Manager v5.4 and R programming.
Results:
Seventeen studies were included in this meta-analysis, encompassing a total of 778 patients. Late gadolinium enhancement was highly prevalent in paediatric hypertrophic cardiomyopathy, with a pooled prevalence of 51% (95% confidence interval, 40–62%). The estimated extent of focal fibrosis expressed as a percentage of left ventricular mass was 4.70% (95% confidence interval, 2.11–7.30%). The presence of late gadolinium enhancement was associated with an increased risk of adverse cardiac events (pooled odds ratio 3.49, 95% confidence interval 1.10–11.09). The left ventricular mass index of late gadolinium enhancement-positive group was higher than the negative group, with a standardised mean difference of 0.91 (95% confidence interval, 0.42–1.41).
Conclusion:
This meta-analysis demonstrates that prevalence of late gadolinium enhancement in paediatric hypertrophic cardiomyopathy is similar to that in the adult population. The presence and extent of late gadolinium enhancement are independent predictors of adverse cardiac events, underscoring their prognostic significance among the paediatric population.
Martha Nussbaum in her The New Religious Intolerance (2012) commits several old forms of epistemic vice including exclusion, orientalism, and colonial discourse. Unsurprisingly, as a result, her text contributes to the production of ignorance about Muslims and Muslim women despite her intention of combating Islamophobia. In this article, I specifically critique Nussbaum's anti-burqa-ban arguments and her pro-airport-profiling stance. To do so, I draw on the work of Audre Lorde and other feminist scholars and scholars of color to express the harms of excluding Muslim voices and misusing Western/white voices in their place. Recalling Edward Said, Marilyn Frye, and María Lugones, I argue that Nussbaum's text is a classic example of orientalism and various forms of colonial discourse.
In this paper, we analyse Turing instability and bifurcations in a host–parasitoid model with nonlocal effect. For a ordinary differential equation model, we provide some preliminary analysis on Hopf bifurcation. For a reaction–diffusion model with local intraspecific prey competition, we first explore the Turing instability of spatially homogeneous steady states. Next, we show that the model can undergo Hopf bifurcation and Turing–Hopf bifurcation, and find that a pair of spatially nonhomogeneous periodic solutions is stable for a (8,0)-mode Turing–Hopf bifurcation and unstable for a (3,0)-mode Turing–Hopf bifurcation. For a reaction–diffusion model with nonlocal intraspecific prey competition, we study the existence of the Hopf bifurcation, double-Hopf bifurcation, Turing bifurcation, and Turing–Hopf bifurcation successively, and find that a spatially nonhomogeneous quasi-periodic solution is unstable for a (0,1)-mode double-Hopf bifurcation. Our results indicate that the model exhibits complex pattern formations, including transient states, monostability, bistability, and tristability. Finally, numerical simulations are provided to illustrate complex dynamics and verify our theoretical results.
The Kaan (“Snake”) kings, a powerful political entity in the Classic Maya Lowlands, were housed in the Early Classic period at Dzibanche, and they moved their capital to Calakmul by the year a.d. 642 (Helmke and Awe 2016; Martin 2020:138–139). Their network of alliance and intermarriage radiated southward, and Waka's early eighth-century queen, Lady K'abel, was from the Kaan bloodline and married in to the Wak lineage, exemplifying the close connection between the two political entities. The discovery of Stela 44 in tunneling efforts in M13-1, the city's important ritual center, allows us to trace political ties between the Kaan and Wak kings to significantly earlier than previously known, which seem to begin around the mid-sixth century. This monument provides insight into three converging lines of evidence supporting the profound alliance these elites had built: first, the accession of a Wak king, Wa'oom Uch'ab Ahk, under the supervision of the Kaan king K'ahk’ Ti’ Ch'ich’; second, the father of the new king, Chak Tok Ich'aak, seems to be connected to La Corona, another early Kaan ally; and third, the mother of Wa'oom Uch'ab Ahk, Ix Ikoom, is also connected to La Corona and the broader Kaan hegemony through her title ix sak wahyis.
The family stress model has, for decades, guided empirical work linking poverty with increased risk of child social-emotional dysfunction. The present study extends this line of work by examining whether child negative emotionality moderates associations between family income, family stress (maternal distress, parental locus of control, and relationship dissatisfaction), and later externalizing and internalizing behavior problems. In a longitudinal population-based sample (n ~ 80,000) of Norwegian children followed from birth through age five (The Norwegian Mother, Father, and Child Cohort Study; MoBa), we examined whether high (vs. moderate or low) negative emotionality families would display: (a) compounding stress (i.e., particularly strong associations between low family income and family stress), (b) diathesis-stress (i.e., particularly strong associations between family stress and behavior problems), or (c) double jeopardy (i.e., both compounding stress and diathesis-stress moderating effects). Negative emotionality significantly moderated the association between family income and behavior problems in a manner most consistent with double jeopardy. As a result, compared with children with moderate/low negative emotionality, the family income-behavior problems association was two to three times larger for those with higher negative emotionality. These findings underscore the active role children may play in family processes that link low family income with behavior problems.
We get money at the cost of life here. Do you think death is not better than this life?Being a Kolbar is darkness. It is unfortunate. You either get shot, or you fall down a mountain, then stay alive but disabled.1 (Arasteh, a Kurdish woman kolbar)
By the end of the Tang Dynasty (618–907 CE), olfactory culture in China had evolved significantly as coveted aromatics continued to be imported and in increasing quantities from Southeast Asia. Although there is no surviving treatise dedicated to aromatics from this period, anecdotes in prose literature describing the uses and curation of scents reveal a process in which imported aromatics were being actively incorporated into existing olfactory culture and accrued new social, aesthetic, and ritual significance. This process is discernible in two major respects. First, a discourse of connoisseurship for aromatics arose in contrast to the conspicuous consumption of imported aromatics that flaunted wealth and status. Secondly, aromatics that were once the privilege of the very few began to be circulated among a wider (admittedly still elite) population, as seen in the case of the dragon brain aromatic in late-Tang and Five Dynasties accounts. By delving into these and related prose narratives and by cross-examining these accounts against other types of records, this article examines how imported aromatic goods shaped the Tang elite's perception of how scent was—and could be—used as part of a socially rooted sensory experience.
Carvajal syndrome is a very rare autosomal recessive cardiocutaneous disorder caused by a desmosomal mutation in exon 24 of the desmoplakin gene. It manifests with woolly hair, epidermolytic palmoplantar keratoderma, and arrhythmogenic right ventricular cardiomyopathy. We herein present a patient with heart failure and dilated cardiomyopathy who was diagnosed with Carvajal syndrome because of dermatologic manifestations.
Case Presentation:
A seven-year-old girl was referred to our clinic due to decompensated heart failure and clinical deterioration. The patient had severe weakness, tachycardia, and tachypnea. She had a complaint of getting tired quickly for three weeks, and she had shortness of breath and abdominal pain for the last two days. She had hepatomegaly and woolly hair. Mild keratoderma was present on the soles of her feet. Echocardiography demonstrated biventricular dilatation, significantly impaired left ventricular systolic function (ejection fraction 22%), and moderate to severe mitral and tricuspid regurgitation. Molecular genetic evaluation was performed because of cutaneous and cardiac findings, which demonstrated a desmoplakin gene mutation. Homozygous mutation c.4297C > T (p.Gln1433*) was identified in desmoplakin gene, and the diagnosis of Carvajal syndrome was confirmed.
Conclusions:
Syndromic types of arrhythmogenic right ventricular cardiomyopathy such as Carvajal syndrome are rare diseases. Awareness about cutaneous manifestations and genetic evaluation would help diagnosis and prevention of sudden death. Genetic counselling is needed in familial cases.
Stylistic shifts in ceramics are often linked with sociopolitical changes, yet adopting new ceramic designs may indicate anything from shared aesthetic appeal to emulation. Focusing on multiple ceramic technologies is critical for understanding ceramic changes as they relate to wider social fluctuations. The relationships between clay and ceramic recipes, and communities of practice, have not been studied at the urban landscape of Angamuco, Michoacán in western Mexico. Petrographic and geochemical analyses of tempers and fabrics indicate that ceramics, including imperial Purépecha (a.d. 1350–1530) vessels, were created from local and regional materials, and that these materials remained relatively stable for over 1,000 years. Ceramic archaeometry in western Mexico has been relatively limited compared to other parts of Mesoamerica, and this study may be compared to future studies in the region.
The widespread significance of tobacco in Mesoamerica is documented in historical and ethnographic sources, yet recovery of the organic remains of this plant from archaeological contexts is rare. Here, the authors present evidence for the ritual use of tobacco at Cotzumalhuapa, Guatemala, during the Late Classic period (AD 650–950). Detection of nicotine in residue analysis of three cylindrical ceramic vases recovered from cache deposits near the El Baúl acropolis suggests that these vessels contained tobacco infusions or other liquid preparations. These results suggest an ancient ritual practice involving tobacco for which there was previously no physical evidence in Mesoamerica.
We prove that the opposite of the category of coalgebras for the Vietoris endofunctor on the category of compact Hausdorff spaces is monadic over $\mathsf {Set}$. We deliver an analogous result for the upper, lower, and convex Vietoris endofunctors acting on the category of stably compact spaces. We provide axiomatizations of the associated (infinitary) varieties. This can be seen as a version of Jónsson–Tarski duality for modal algebras beyond the zero-dimensional setting.
Many court observers have argued that judges are capable of avoiding the use of extraneous factors in decision-making. This study examines the influence of seemingly irrelevant heuristics on real-world courtroom proceedings. Drawing on theories from neighboring disciplines, I hypothesize that physically attractive attorneys have greater success in US federal court. Using a generalizable causal inference strategy and a dataset of over 1,000 cases and 3,000 votes, I find support for my expectations using multiple measures of attractiveness. These findings raise serious normative concerns about equality and underscore the need to adjust traditional models of judicial behavior to account for inherent biases.
The true characterization of elite germplasm is of utmost importance for accelerating the crop breeding programme. The Indian dolichos bean [Lablab purpureus (L.) var. typicus Prain] has the potential to improve nutritional and food security. In the present investigation, a total of 21 genotypes of dolichos bean, comprising local collections mainly, along with one standard check (Kashi Sheetal) were evaluated in a complete randomized block design with three replications for two consecutive years, 2021–22 to 2022–23 for the perusal of the genetic variability. Analysis of variance revealed significant differences among all the genotypes for all the characters. PCV and GCV estimates revealed very little influence of environment on the expression of traits under study. High heritability (>90%) estimates coupled with high genetic advance as a percent of the mean were observed for flower attributes, pod length, average weight of 10 pods, pod yield and protein content. The principal component analysis revealed that the first two components cumulatively accounted for more than 50% of total variability. The present investigation revealed that the genotypes, RLBDL-S-8, RLBDL-S-14 and RLBDL-S-4-5 were stable across the years and genotype RLBDL-S-8 exhibited the highest yield potential, which can be used effectively in the development of high yielding varieties of dolichos bean in the Bundelkhand region. The study also revealed the presence of wide genetic variability in the studied local accessions which is a prerequisite for the genetic improvement of crop plants. High heritability and genetic advancement indicated the scope of selection in the crop improvement.
Standardisation is a product of the second wave of the Industrial Revolution in Europe and North America. This article examines how Western standardisation practices were introduced, transmitted, and promoted in China during the first half of the twentieth century. In particular, it looks at the critical role played by British, American, and local Chinese engineers in the transmission process. The topics covered in the present article have seldom been considered, and this article tries to fill the gap in scholarship. It analyses the shifting patterns of various standardisation efforts that are closely related to the governance of both cities and the wider nation. Work examined includes that of the Engineering Society of China, led by British engineers, which initiated standardisation in the Shanghai International Settlement in the early twentieth century; that of the Association of Chinese and American Engineers, founded by engineers of China and the USA, which, after World War I, began to implement the standardisation of railway infrastructure, with the cooperation of the Ministry of Transportation of the Beijing government; and efforts in the 1930s under the Nanjing government to establish an ‘engineering’ or ‘technocratic’ state, which included the execution of national schemes for the development of industrial standardisation. From the period of World War I until the 1930s, the orientation and practices of American standardisation strategies dominated China; then, due to the worsening situation of the Chinese–Japanese War, ideological tendencies and national strategies for standardisation began to diverge.