To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
An isolated Leidenfrost droplet levitating over its own vapour above a superheated flat substrate is considered theoretically, the superheating for water being up to several hundred degrees above the boiling temperature. The focus is on the limit of small, practically spherical droplets of several tens of micrometres or less. This may occur when the liquid is sprayed over a hot substrate, or just be a late life stage of an initially large Leidenfrost droplet. A rigorous numerically assisted analysis is carried out within verifiable assumptions such as quasi-stationarities and small Reynolds/Péclet numbers. It is considered that the droplet is surrounded by its pure vapour. Simple formulae approximating our numerical data for the forces and evaporation rates are preliminarily obtained, all respecting the asymptotic behaviours (also investigated) in the limits of small and large levitation heights. They are subsequently used within a system of ordinary differential equations to study the droplet dynamics and take-off (drastic height increase as the droplet vapourises). A previously known quasi-stationary inverse-square-root law for the droplet height as a function of its radius (at the root of the take-off) is recovered, although we point out different prefactors in the two limits. Deviations of a dynamic nature therefrom are uncovered as the droplet radius further decreases due to evaporation, improving the agreement with experiment. Furthermore, we reveal that, if initially large enough, the droplets vanish at a universal finite height (just dependent on the superheat and fluid properties). Scalings in various distinguished cases are obtained along the way.
An exact solution is developed for bubble-induced acoustic microstreaming in the case of a gas bubble undergoing asymmetric oscillations. The modelling is based on the decomposition of the solenoidal, first- and second-order, vorticity fields into poloidal and toroidal components. The result is valid for small-amplitude bubble oscillations without restriction on the size of the viscous boundary layer $(2\nu /\omega )^{1/2}$ in comparison to the bubble radius. The non-spherical distortions of the bubble interface are decomposed over the set of orthonormal spherical harmonics $Y_{n}^{m}(\theta , \phi )$ of degree $n$ and order $m$. The present theory describes the steady flow produced by the non-spherical oscillations $(n,\pm m)$ that occur at a frequency different from that of the spherical oscillation, as in the case of a parametrically excited surface oscillation. The three-dimensional aspect of the streaming pattern is revealed as well as the particular flow signatures associated with different asymmetric oscillations.
Oscillatory flows induced by a monochromatic forcing frequency $\omega$ close to a planar surface are present in many applications involving fluid–matter interaction such as ultrasound, vibrational spectra by microscopic pulsating cantilevers, nanoparticle oscillatory magnetometry, quartz crystal microbalance and more. Numerical solution of these flows using standard time-stepping solvers in finite domains present important drawbacks. First, hydrodynamic finite-size effects scale as $1/L_{\parallel }^2$ close to the surface and extend several times the penetration length $\delta \sim \omega ^{-1/2}$ in the normal $z$ direction and second, they demand rather long transient times $O(L_z^2)$ to allow vorticity to diffuse over the computational domain. We present a new frequency-based scheme for doubly periodic (DP) domains in free or confined spaces which uses spectral-accurate solvers based on fast Fourier transform in the periodic $(xy)$ plane and Chebyshev polynomials in the aperiodic $z$ direction. Following the ideas developed for the steady Stokes solver (Hashemi et al. J. Chem. Phys. vol. 158, 2023, p. 154101), the computational system is decomposed into an ‘inner’ domain (where forces are imposed) and an outer domain (where the flow is solved analytically using plane-wave expansions). Matching conditions leads to a solvable boundary value problem. Solving the equations in the frequency domain using complex phasor fields avoids time-stepping and permits a strong reduction in computational time. The spectral scheme is validated against analytical results for mutual and self-mobility tensors, including the in-plane Fourier transform of the Green function. Hydrodynamic couplings are investigated as a function of the periodic lattice length. Applications are finally discussed.
Cinq générations doivent actuellement cohabiter sur le marché du travail, ce qui peut entraîner plusieurs bénéfices, mais également un risque de tensions et de conflits susceptibles de nuire à la collaboration des équipes de travail et à la santé des personnes vieillissantes. La coopération intergénérationnelle au travail (CIT) a été relevée dans la littérature comme une avenue intéressante pour diminuer le risque de conflits intergénérationnels, mais elle demeure peu concrètement définie. Cette étude vise à proposer une définition opérationnelle du concept de coopération intergénérationnelle au travail à l’aide de la méthode d’analyse de Walker and Avant (2019). Quarante-huit manuscrits ont été répertoriés, permettant d’identifier huit attributs caractérisant la CIT, sept antécédents et six conséquents du concept. Cette étude fait ressortir le rôle des différents acteurs dans la CIT, met en lumière les bénéfices de la CIT et permet de considérer son rôle en prévention des lésions professionnelles.
Women legislators face a variety of gendered barriers both outside and inside the legislature. Yet, little previous scholarship has quantitatively examined whether legislative insiders are biased against women and their accomplishments. We explore a new potential explanation for gender inequity in legislatures: that women in office may get less credit than men for similar achievements. If legislative insiders systematically undervalue women’s work, women will have a harder time gaining influence within the chamber; alternatively, those working in and with the legislature may be uniquely aware of the effort that goes into representational activities and can observe the work that women perform firsthand. To examine this question, we combine elite evaluations of legislators from the North Carolina General Assembly with data on committee assignments, legislative effectiveness, electoral performance, and more. We find little systematic evidence that women legislators’ accomplishments are valued less than those of the men with whom they serve.
This paper focuses on the discursive connection between the notion of autonomy and the ageing-in-place policy approach, in a context of population aging and budgetary restraint. We argue that these central elements of the policy discourse on ageing represent a governance strategy that defines ageing in place as the prevailing standard for ageing well. Through an analysis of ageing policy documents released by the Québécois government between 2012 and 2023, this paper shows a disconnect between national policy frameworks and the reality of ageing in place. The issue of ageing in place is strongly bound up with the idea of autonomy, which is mainly expressed in terms of responsibility and freedom of choice, while its implementation overlooks the social structural determinants of individual autonomy and their impact on older people’s opportunities and processes of ageing in place.
A stochastic wavevector approach is formulated to accurately represent compressible turbulence subject to rapid deformations. This approach is inspired by the incompressible particle representation model of Kassinos & Reynolds (1994), and preserves the exact nature of compressible rapid distortion theory (RDT). The adoption of a stochastic – rather than Fourier – perspective simplifies the transformation of statistics to physical space and serves as a starting point for the development of practical turbulence models. We assume small density fluctuations and isentropic flow to obtain a transport equation for the pressure fluctuation. This results in four fewer transport equations compared with the compressible RDT model of Yu & Girimaji (Phys. Fluids, vol. 19, 2007, 041702). The final formulation is closed in spectral space and only requires numerical approximation for the transformation integrals. The use of Monte Carlo for unit wavevector integration motivates the representation of the moments as stochastic variables. Consistency between the Fourier and stochastic representation is demonstrated by showing equivalency between the evolution equations for the velocity spectrum tensor in both representations. Sample clustering with respect to orientation allows for different techniques to be used for the wavevector magnitude integration. The performance of the stochastic model is evaluated for axially compressed turbulence, serving as a simplified model for shock–turbulence interaction, and is compared with linear interaction approximations and direct numerical simulation (DNS). Pure and compressed sheared turbulence at different distortion Mach numbers are also computed and compared with RDT/DNS data. Finally, two additional deformations are applied and compared with solenoidal and pressure-released limits to demonstrate the modelling capability for generic rapid deformations.
Notre société segmentée par l’âge offre peu de possibilités d’interactions intergénérationnelles authentiques. Cela contribue aux stéréotypes et préjugés envers les personnes de tous âges, particulièrement les adultes aînés. Pour favoriser une société plus inclusive et lutter contre l’âgisme, un changement de paradigme sociétal devient nécessaire. À partir d’une recherche basée sur la conception et l’apprentissage intergénérationnel, nous avons cherché à mieux caractériser ces apprentissages afin de développer des formations spécifiques pour les appuyer. Basé sur un questionnaire préliminaire (n=79), nous avons conçu un atelier pilote (français/anglais) avec huit adultes aînées et huit jeunes adultes au cours duquel les participants ont dû réaliser en binôme une vidéo sur TikTok. Nos résultats indiquent que l’apprentissage intergénérationnel doit se fonder sur une pédagogie active, les activités et les objectifs pédagogiques doivent être multiples pour être réalisées en binômes intergénérationnels, le format doit permettre de développer une relation de confiance et l’évaluation doit être personnelle.
Discussions about economic equality have, in recent years, extended beyond considerations of income distribution to encompass the distribution of wealth and its intergenerational transfer. Driven by new and more frequent data, a better understanding is emerging of the concentration of wealth within society and the dynamics of its transfer between generations.
This article contributes to that discussion by assessing the economic and social rationales for the taxation of intergenerational wealth transfers. It outlines the social policy case for inheritances taxes grounded in vertical equity principles. Then it presents comparative data on household wealth across high-income European countries before focusing on one of these, Ireland, to consider whether current inheritance taxation policies counter or perpetuate these inequalities. Focusing on that system, the article explores a range of inheritance taxation reforms intended to address wealth inequality while providing recurring funds for public services and redistribution.
Kawasaki disease is a leading cause of acquired heart disease in children in the developed world, characterised by acute systemic vasculitis, with a complex aetiology that remains poorly understood. Recent studies have highlighted the potential anti-inflammatory effects of Interleukin-35 in various proinflammatory and cardiovascular conditions. However, the relationship between Interleukin-35 gene polymorphisms and Kawasaki disease susceptibility, particularly in Chinese children, has not been well-explored.
In this study, we investigated the association between five Interleukin-35 single-nucleotide polymorphisms—rs2243115, rs2243123, rs583911, rs353698, and rs2302164—and Kawasaki disease in a cohort of Chinese children. A total of ninety-four Kawasaki disease patients and one hundred healthy controls were enrolled, with the Kawasaki disease patients further divided into subgroups based on the presence or absence of coronary artery lesions and incomplete or complete Kawasaki disease. Genotyping of Interleukin-35 polymorphisms was performed using the MassARRAY system.
The results showed the GT + GG genotypes and G allele of rs2243115 (T > G) were significantly more prevalent in Kawasaki disease patients with coronary artery lesions than in those without coronary artery lesions, suggesting a possible association with the development of coronary artery lesions. Additionally, the G allele of rs353698 (A > G) was more frequently observed in the incomplete Kawasaki disease group compared to the complete Kawasaki disease group, suggesting a possible association with the risk of incomplete Kawasaki disease.
Travelling wave charges lying on the insulating walls of an electrolyte-filled capillary give rise to oscillatory modes which vanish when averaged over the period of oscillation. They also give rise to a zero mode (a unidirectional, time-independent velocity component) which does not vanish. The latter is a nonlinear effect caused by continuous symmetry breaking due to the quadratic nonlinearity associated with the electric body force in the time-dependent Stokes equations. In this paper, we provide a unified view of the effects arising in boundary-driven electrokinetic flows (travelling wave electroosmosis) and establish the universal behaviour exhibited by the observables. We show that the incipient velocity profiles are self-similar implying that those obtained with a single experimental configuration can be employed again to attain further insights without the need of repeating the experiment. Certain results from the literature are recovered as special cases of our formulation and we resolve certain paradoxes having appeared in the past. We present simple theoretical expressions, depending on a single-fit parameter, that reproduce these profiles, which could thus provide a rapid test of consistency between our theory and future experiment. The effect becomes more pronounced when reducing the transverse dimension of the system, relative to the velocity direction, and increasing the excitation wavelength, and can therefore be employed for unidirectional transport of electrolytes in thin and long capillaries. General relations, expressing the zero mode velocity in terms of the electric potential and the geometry of the system only, can thus be easily adapted to alternative experimental settings.
The duration of undiagnosed or untreated bipolar disorder (DUBD) has become a focus of research interest. However, its relationship with clinical characteristics and outcomes remains poorly understood.
Aims
The objective of this systematic review and meta-analysis was to examine DUBD and explore its relationships with clinical characteristics and outcomes in bipolar disorder.
Methods
We conducted a systematic search of the literature to identify studies reporting on DUBD and its relationships with clinical characteristics and outcomes including frequency of relapse into mood episodes, severity and persistence of mood symptoms, functional and cognitive measures, suicidality, hospital admission rate, and comorbidities such as substance use disorders.
Results
Thirty articles met inclusion criteria for the systematic review, and 23 studies were included in the three different sets of meta-analyses. The pooled mean DUBD across all studies was 9.10 years. Early onset, depression as the polarity of the first mood episode, lifetime suicide attempts, comorbid anxiety and alcohol use disorders, and family history of bipolar disorder were associated with significantly longer DUBD, whereas diagnosis of bipolar I disorder and lifetime psychotic symptoms were associated with shorter DUBD. Studies that investigated outcomes subsequent to the diagnosis of bipolar disorder yielded conflicting results.
Conclusion
DUBD may be associated with certain adverse outcomes. This association indicates the importance of adopting a more comprehensive approach to assessing mood disorders, with an emphasis on prioritising early screening for bipolar disorder. The significant heterogeneity among included studies suggests a need for improved methodological rigour in future research.
Syllable integrity, the idea that the content of syllables may not be metrified separately, is often taken to be an inviolable constraint of grammar. This has been challenged in recent work, though the data are often subject to competing analyses. This article claims that syllable integrity is readily violable in Naasioi. Evidence from stress, the minimal word and metrically sensitive allomorphy supports an analysis of the metrical system operating on bimoraic feet, and in which long vowels can be metrified separately. Despite this, there is also evidence, in the form of vowel shortening and truncation, to indicate that long vowels constitute a single syllable. The net result is a stress system which systematically ignores syllables, a state of affairs which allows for syllable integrity violations to arise.
A public health emergency was declared for the opioid crisis in 2017 and remains in place. Between 2017-2024, there were 164 billion dollar disasters. People who use drugs (PWUDs) are highly susceptible to disasters; however adaptive capacity of opioid treatment programs (OTP) is not well understood. Identifying and addressing gaps to increase resilience and reduce morbidity and mortality among PWUDs is critical.
Methods
A semi-structured interview guide with 8 questions was developed to assess how disasters impact service provision and other aspects of OTPs. OTP leaders, government officials, community health navigators, and advocates received an email invitation to complete an interview via Zoom. Transcripts were independently hand coded to inductively identify themes.
Results
Eleven interviews were completed. Four themes were identified including client challenges securing housing and reliable transportation, disaster-related communication barriers, stigma around help seeking, and issues related to policies and practices such as regulations and insurance coverage that are inflexible during a disaster.
Conclusions
Disruptions to OTPs during disasters require preparedness planning adaptations like more flexible guest dosing. The ongoing public health emergency of the opioid epidemic and the increasing frequency and severity of climate and weather emergencies requires adaptations to a highly regulated system to address vulnerabilities.
Parvovirus B19 (PVB19) myocarditis is a life-threatening condition with high morbidity and mortality in children. While electrocardiograms are commonly used in the early assessment of myocarditis, no specific electrocardiogram pattern has been consistently linked to PVB19. The objective of this study is to identify a distinctive electrocardiogram pattern associated with PVB19 myocarditis and evaluate its diagnostic accuracy.
Methods:
This retrospective case–control study included 77 paediatric patients diagnosed with acute myocarditis at a single centre in Barcelona over 16 years (August 2008–September 2024). Twenty patients had PVB19 myocarditis, confirmed by polymerase chain reaction in blood or endomyocardial biopsy, while 57 patients had myocarditis caused by other viruses. Electrocardiogram were assessed by three cardiologists blinded to the aetiological diagnosis.
Results:
A specific electrocardiogram pattern in the limb leads, characterised by peaked P waves, low QRS complex voltages, and altered repolarisation (manifesting as negative or flat T waves, with or without QTc prolongation), was observed in 14 of 20 patients (70%) with PVB19 myocarditis. Two additional patients exhibited low voltages and altered repolarisation without peaked P waves, and all demonstrated repolarisation abnormalities. In contrast, only 1 of 57 patients with myocarditis from other viruses exhibited the full electrocardiogram pattern. The pattern demonstrated a specificity of 98% and a sensitivity of 70% for PVB19 myocarditis.
Conclusion:
The identified electrocardiogram pattern shows strong diagnostic specificity for PVB19 myocarditis in paediatric patients and may serve as a useful early diagnostic tool. Further multicentre studies are needed to confirm these findings and explore their clinical implications.
Today, two touchstones of the conservative legal movement are support for the unitary executive theory and skepticism of affirmative action policies. This article reveals a connection between these two positions, demonstrating how policy disputes over civil rights contributed to conservative efforts to increase and legitimize presidential control over the bureaucracy through the controversial claim that the president possesses the whole executive power under Article II. Specifically, I examine two intertwined controversies from 1983, which pit the Reagan White House and Department of Justice (DOJ) against the Equal Employment Opportunity Commission (EEOC) and U.S. Commission on Civil Rights (USCCR), two agencies that Reagan officials viewed as obstacles to pursuing its preferred civil rights agenda. Conflicts between the DOJ and EEOC led the administration to deploy the unitary executive theory to help centralize control over its civil rights litigation strategy, while clashes with the USCCR spurred the administration to assert the theory's tenets amid battles over that agency's reauthorization. While these episodes yielded mixed political and legal outcomes, the early articulations of the unitary executive theory that emerged helped to elaborate and advance a controversial constitutional doctrine about presidential power that has become increasingly consequential over time.
Large-eddy simulation (LES) is performed to study the tip vortex flow in a ducted propulsor geometry replicating the experiments of Chesnakas & Jessup (2003, pp. 257–267), Oweis et al. (2006a J. Fluids Engng128, 751–764) and Oweis et al. (2006b J. Fluids Engng128, 751–764). Inception of cavitation in these marine propulsion systems is closely tied to the unsteady interactions between multiple vortices in the tip region. Here LES is used to shed insight into the structure of the tip vortex flow. Simulation results are able to predict experimental propeller loads and show agreement with laser Doppler velocimetry measurements in the blade wake at design advance ratio, $J=0.98$. Results show the pressure differential across the blade produces a leakage vortex which separates off the suction side blade tip upstream of the trailing edge. The separation sheet aft of the primary vortex separation point is shown to take the form of a skewed shear layer which produces a complex arrangement of unsteady vortices corotating and counter-rotating with the primary vortex. Blade tip boundary layer vortices are reoriented to align with the leakage flow and produce instantaneous low-pressure regions wrapping helically around the primary vortex core. Such low-pressure regions are seen both upstream and downstream of the propeller blade trailing edge. The trailing edge wake is found to only rarely have a low-pressure vortex core. Statistics of instantaneous low pressures below the minimum mean pressure are found to be concentrated downstream of the blade’s trailing edge wake crossing over the primary vortex core and continue in excess of 40 % chord length behind the trailing edge. The rollup of the leakage flow duct boundary layer behind the trailing edge is also seen to produce counter-rotating vortices which interact with the primary leakage vortex and contribute to strong stretching events.
We prove that the class of separably algebraically closed valued fields equipped with a distinguished Frobenius endomorphism $x \mapsto x^q$ is decidable, uniformly in q. The result is a simultaneous generalization of the work of Chatzidakis and Hrushovski (in the case of the trivial valuation) and the work of the first author and Hrushovski (in the case where the fields are algebraically closed).
The logical setting for the proof is a model completeness result for valued fields equipped with an endomorphism $\sigma $ which is locally infinitely contracting and fails to be onto. Namely, we prove the existence of a model complete theory $\widetilde {\mathrm {VFE}}$ amalgamating the theories $\mathrm {SCFE}$ and $\widetilde {\mathrm {VFA}}$ introduced in [5] and [11], respectively. In characteristic zero, we also prove that $\widetilde {\mathrm {VFE}}$ is NTP$_2$ and classify the stationary types: they are precisely those orthogonal to the fixed field and the value group.