In the years 1947–57, following a turbulent retirement, Ugo Cerletti, the father of electroconvulsive therapy (ECT) (1938), invested his energies in a new audacious project conceived as an extension of his ECT research. Forced to leave the direction of the Sapienza University Clinic, he got funds from the National Research Council of Italy to carry out his experimental activities, and founded a ‘Center for the study of the physiopathology of Electro-shock’ in Rome. The Center was aimed at studying liquid substances extracted from electro-shocked animals’ brains that Cerletti named acroagonine and injected into human patients. Inspired by coeval literature, Cerletti believed that electroshock efficacy was due to stimulating some homeostatic processes in the brain, specifically in the meso-diencephalic area (i.e. involving neuroendocrine response in the hypothalamic–pituitary–adrenal axis). Cerletti’s team wished not only to find these effects, but also to reproduce them. With this hypothesis, that proved ineffective, Cerletti anticipated intuitions on the neuroendocrine effects of ECT and the necessity for the development of psychopharmacology. In this article, I cross-combined previously unexplored archival materials stored at Sapienza University of Rome (‘ES Section’) with established bibliographic and archival sources.

On 24 June 2022, the Contracting Parties of the Energy Charter Treaty (ECT) finalized discussions on the modernization of the treaty. After fifteen rounds of negotiations, an agreement in principle was reached to be adopted by the Energy Charter Conference on 22 November 2022 in Ulaanbaatar, Mongolia.1 The ECT, adopted in 1994, establishes a legal framework that aims to promote international cooperation in the energy sector.2 It has a membership of 53 countries primarily from Europe and Central Asia, as well as the European Union (EU) and the European Atomic Energy Community. In recent years, the ECT attracted widespread public attention due to its impact on states’ environmental and climate policies. Particularly, the treaty’s provisions on investment protection, with investor-to-state dispute settlement (ISDS) at the centre, allow foreign investors in the energy sector to challenge adverse state action before international arbitration and claim compensation for measures affecting their business activities. Fossil fuel investors have increasingly used the ECT to challenge environmental and climate measures, such as phasing out coal-fired power generation, banning offshore oil drilling in coastal areas, and prohibiting gas fracking projects. Such cases have fuelled concerns regarding the abilities of governments to roll-out large-scale climate action. The Intergovernmental Panel on Climate Change (IPCC) has warned that international investment agreements (IIAs) like the ECT could ‘be used by fossil-fuel companies to block national legislation aimed at phasing out the use of their assets’.3 With some of these damage claims running into billions of euros, the ECT enables fossil fuel investors to offload the costs and risks associated with their affected assets onto society at large in the face of necessary climate action. This would go, in the words of the editorial board of the Financial Times, against the ‘heart of the capitalist social contract’ and the ‘ability of markets to deal adequately with the challenge of climate change’.4

In this paper, I will examine the Supreme Court of the United States’ (SCOTUS) arguments in the majority decision in Dobbs v. Jackson Women’s Health Organization, and I will show how some of those arguments are flawed. Primarily, I will show that the right to bodily autonomy is a well-established right, both in the courts and in societal practices, and that the right to an abortion should be understood as an example of the right to bodily autonomy or bodily integrity. Second, I will examine the justices’ arguments that viability is not a reasonable place to restrict abortion access, in contrast to both Roe v. Wade and Planned Parenthood v. Casey, and will offer arguments that defend viability as a valid point to limit abortion access. Third, I will highlight some politicians’ goals to enact a federal ban on abortion, and show how the attempt to pass Personhood Amendments is a pathway for doing so. The upshot of this essay to is show how the SCOTUS decision is flawed, and how granting personhood to “potential life” has consequences that extend beyond abortion access.

This article provides a corpus-driven overview of the ‘epistemic space’ surrounding the use of two lockwords of Early and Late Modern English writings on midwifery and childbirth, child and uterus. Rather than searching for epistemic stance markers themselves, this study employs the ‘bottom-up’ approach by examining the propositions containing these lockwords, and then seeing what particular epistemic meanings are signalled by the surrounding discourse context. Both treatises and periodicals representative of medical writing from the sixteenth through the eighteenth centuries are examined, thus allowing any diachronic trends characteristic of a period that witnessed much change in midwifery practices, and medicine more broadly, to be uncovered. Data are drawn from the Early Modern English Medical Texts (EMEMT) and Late Modern English Medical Texts (LMEMT) corpora.

Paul-Louis Simond’s 1898 experiment demonstrating fleas as the vector of plague is today recognised as one of the breakthrough moments in modern epidemiology, as it established the insect-borne transmission of plague. Providing the first exhaustive examination of primary sources from the Institut Pasteur’s 1897–98 ‘India Mission’, including Simond’s notebooks, experiment carnets and correspondence, and cross-examining this material with colonial medical sources from the first years of the third plague pandemic in British India, the article demonstrates that Simond’s engagement with the question of the propagation of plague was much more complex and ambiguous than the teleological story reproduced in established historical works suggests. On the one hand, the article reveals that the famous 1898 experiment was botched, and that Simond’s misreported its ambiguous findings for the Annales de l’Institut Pasteur. On the other hand, the article shows that, in the course of his ‘India Mission’, Simond framed rats as involved in the propagation of plague irreducibly in their relation to other potential sources of infection and not simply in terms of a parasitological mechanism. The article illuminates Simond’s complex epidemiological reasoning about plague transmission, situating it within its proper colonial and epistemological context, and argues for a new historical gaze on the rat as an ‘epidemiological dividual’, which highlights the relational and contingent nature of epidemiological framings of the animal during the third plague pandemic.

This paper investigates two New Kingdom Egyptian texts pertaining to labour regulation: the Karnak Decree of Horemheb and the Nauri Decree of Seti I. They focus on combating the unauthorized diverting of manpower and represent the oldest Egyptian texts (fourteenth–thirteenth century BCE) explicitly concerned with the legal dimension of managing the workforce. After a brief historical overview, the paper outlines each text's key content and stylistic features. It shows that while some of these are likely native to Egypt, others may have been imported from Mesopotamia. More specifically, it appears that the sentence structure is native Egyptian, but the sanctions deployed are likely of foreign origin, aligning more closely to the contemporary punitive tradition of Mesopotamia. This is probably no coincidence, given the close contact between Egypt and the broader Near East at that time. This uptake of foreign ideas may have achieved more efficient labour regulation by enforcing stricter rules for non-compliance while simultaneously maintaining a veneer of Egyptian authenticity in line with official state ideology.

John Witte, Jr.’s book The Blessings of Liberty contains an important message about the origins and continuing relevance of religious liberty. Based on careful historical analysis of the development of religious liberty in England and the US, Witte demonstrates the importance of Protestant thinking both to the right and to human rights more generally. In the process he refutes both Christian and post-Enlightenment sceptics. His discussion of contemporary US and European law shows how much the right is still needed today, despite the claims of contemporary scholars that freedom of religion and belief is a redundant right.

As the climate and biodiversity crises gain unprecedented attention, many governments across the global north are taking legislative steps to address deforestation in supply chains linked to their domestic consumption or commercial activities, among them, the United Kingdom (UK) and the European Union (EU).1

This article examines the emergence of modern psychiatric discourse under the culturally Islamic yet radically secular context of the early Turkish republic (1923-1950). To do so, it focuses on the psychiatric publications of Mazhar Osman [Uzman] (1884-1951), the widely acknowledged “father” of modern Turkish psychiatry; and aims to genealogically trace his scientific project of reconceptualizing ruh, an Arabo-Turkish concept that predominantly refers to transcendental soul, rendering it physiologically within the framework of biological-descriptive psychiatry. The article consequently addresses the elusive and multilayered psychiatric language emerged in Turkey as a result of modern psychiatry’s interventions into a field that was previously defined by religion and indigenous traditions. Attempting to contextualize republican psychiatric discourse within the cultural and socio-political circumstances that has produced it, the article sheds light on how the new psychiatric knowledge propagated by Mazhar Osman was formulated in constitutive contradistinction to religious or traditional discourses, explicitly associating them with the Ottoman past and its alleged backwardness, hence reverberating with the Kemalist project of modern Turkish state building. Furthermore, by focusing on the complexities of the Turkish psychiatric language and the contestations it has generated, the article aims to reflect on the ways in which the Turkish psychiatric language was (and presumably still is) haunted by earlier forms of Islamic knowledge and traditions, despite modern psychiatry’s as well as modern secular state’s systematic and authoritative attempts to erase them for good.

In the late Soviet period, a great deal of research was conducted on older people’s health, with the Institute of Gerontology Academy of Medical Sciences (AMN) USSR in Kyiv spearheading a great deal of this. Of particular interest was older people’s ability to work beyond retirement age, the issue of premature ageing, as well as physical activity, diet and living conditions. Many of these interests came under the concept of ‘gerohygiene’, which also reflected the Soviet Union’s prophylactic approach to eldercare (and healthcare more generally). Discussions about older people and Soviet research on gerohygiene are important for furthering our understanding of ideas around healthy ageing and the Soviet project more generally. The Soviet, and indeed socialist, research on gerohygiene sheds light on ideas around active ageing, premature ageing and work practices for older people. It also shows that the role of old people belonged to the wider Soviet effort of contributing to the communist project and shaping society. In this article, I define and examine the broad concept of ‘gerohygiene’ and then assess how gerohygiene applied to older people’s health in relation to both physical activity and labour.

This project investigates the intonation of canonical (information-seeking) and non-canonical wh-in-situ echo questions conveying repetition and surprise in Northern Peninsular Spanish. Data from 14 female participants were collected via a contextualised elicitation task. The following correlates were examined: (i) the melodic curve of the wh-in-situ question, (ii) the nuclear peak (in Hz), (iii) the wh-tonal range (i.e. the difference between the lowest nuclear Low and the highest boundary High), and (iv) the nuclear contour. Results show that all wh-in-situ questions investigated display similar melodic curves and nuclear contours, but canonical questions have significantly lower nuclear peaks and wh-tonal ranges than non-canonical questions. Echo-repetition and echo-surprise questions also differ in nuclear peak and wh-tonal range. We propose a tentative analysis, whereby canonical in-situ questions have a final H% boundary tone, in contrast to non-canonical questions, which have an extra-High (upstepped) final boundary tone (¡H%).

As opposed to overdemanding principles which ask individuals to sacrifice too much, there are overpermissive principles which ask individuals to sacrifice too little. Determining the extent to which one should sacrifice often comes with the need of understanding what is of moral significance. By analysing different readings of moral significance, and singling out one specific interpretation of moral significance which links moral significance to gaining or losing a considerable amount of welfare, I demonstrate that one of the well-known principles of Peter Singer, the Weaker Principle of Sacrifice, is overpermissive as it exempts deliberately cultivated morally significant lavish pursuits from the domain of sacrifice. Overpermissiveness not only renders moral principles unreasonably broad but also causes burdens to be distributed unjustifiably in a comparative sense, where some parties are assigned a moral obligation whereas others are not.

Contemporary population ethics is dominated by views that aggregate by summing, whether of well-being or of some construct based on well-being. In contrast, average well-being is generally considered axiologically irrelevant. To many of us, however, the number of future people does not seem important, as long as it is sufficient to enable rich and varied life experiences, and as long as the population continues throughout time. It therefore seems relatively plausible to aggregate future well-being by averaging. In particular, it seems plausible to value high average well-being at any particular time, and to do so for all future times. I present a time-sensitive version of the Average View that underpins such axiological intuitions. I also address a series of issues and objections that confront such a view.

On 25 June 2021, a historic fisheries Agreement entered into force: The Agreement to Prevent Unregulated High Seas Fisheries in the Central Arctic Ocean (CAO). Nine countries and the European Union agreed to refrain from any commercial fishing in the CAO and to jointly undertake a scientific effort to understand ecosystem dynamics, including fish populations. This was the first multilateral Agreement to take a legally binding, precautionary approach to protect an area from commercial fishing before fishing had begun. The Agreement is a textbook example of the precautionary principle as it works to take “preventive action in the face of uncertainty.” However, despite the precautionary principle’s popularity with natural resource academics, it is rare for countries to forego economic benefits and to adopt this approach in managing resources. So, what made this Agreement possible? And what can we learn from this Agreement that could provide guidance on other resource management challenges? This paper explores the unique conditions that made this Agreement possible and examines how success was achieved by the interrelationships of science, policy, legal structures, politics, stakeholder collaboration, and diplomacy. In summary, this paper concludes that a series of factors helped make this Agreement possible, including but not limited to: scientific breakthroughs coupled with science-based legal frameworks; proactive partnerships between industry, environmental non-profits, and government; willingness of international stakeholders to learn from prior mistakes; and a nation willing to be the first-mover in foregoing future economic profits within their own Exclusive Economic Zone to order to benefit ecosystems beyond their waters.