In this exploratory study, designers’ preferred learning media in learning to design for Additive Manufacturing was explored. Furthermore, by deploying an online survey questionnaire, factors such as years of experience, and the categories of products designed were explored to understand how they influence designers’ learning media with a response from 201 respondents. The results show that designers have learned how to design for AM through experimentation and present the first step towards developing an appropriate Design for Additive Manufacturing knowledge dissemination approach.

TwinsMX registry is a national research initiative in Mexico that aims to understand the complex interplay between genetics and environment in shaping physical and mental health traits among the country’s population. With a multidisciplinary approach, TwinsMX aims to advance our knowledge of the genetic and environmental mechanisms underlying ethnic variations in complex traits and diseases, including behavioral, psychometric, anthropometric, metabolic, cardiovascular and mental disorders. With information gathered from over 2800 twins, this article updates the prevalence of several complex traits; and describes the advances and novel ideas we have implemented such as magnetic resonance imaging. The future expansion of the TwinsMX registry will enhance our comprehension of the intricate interplay between genetics and environment in shaping health and disease in the Mexican population. Overall, this report describes the progress in the building of a solid database that will allow the study of complex traits in the Mexican population, valuable not only for our consortium, but also for the worldwide scientific community, by providing new insights of understudied genetically admixed populations.

When is speech on social media toxic enough to warrant content moderation? Platforms impose limits on what can be posted online, but also rely on users’ reports of potentially harmful content. Yet we know little about what users consider inadmissible to public discourse and what measures they wish to see implemented. Building on past work, we conceptualize three variants of toxic speech: incivility, intolerance, and violent threats. We present results from two studies with pre-registered randomized experiments (Study 1, $ N=\mathrm{5,130} $; Study 2, $ N=\mathrm{3,734} $) to examine how these variants causally affect users’ content moderation preferences. We find that while both the severity of toxicity and the target of the attack matter, the demand for content moderation of toxic speech is limited. We discuss implications for the study of toxicity and content moderation as an emerging area of research in political science with critical implications for platforms, policymakers, and democracy more broadly.

Astigmatism and myopia are two common ocular refractive errors that can impact daily life, including learning and productivity. Current knowledge suggests that the etiology of these conditions is the result of a complex interplay between genetic and environmental factors. Studies in populations of European ancestry have demonstrated a higher concordance of refractive errors in monozygotic (MZ) twins compared to dizygotic (DZ) twins. However, there is a lack of studies on genetically informative samples of multi-ethnic ancestry. This study aimed to estimate the genetic contribution to astigmatism and myopia in the Mexican population. A sample of 1399 families, including 243 twin pairs and 1156 single twins, completed a medical questionnaire about their own and their co-twin’s diagnosis of astigmatism and myopia. Concordance rates for astigmatism and myopia were estimated, and heritability and genetic correlations were determined using a bivariate ACE Cholesky decomposition method, decomposed into A (additive genetic), C (shared environmental) and E (unique environmental) components. The results showed a higher concordance rate for astigmatism and myopia for MZ twins (.74 and .74, respectively) than for DZ twins (.50 and .55). The AE model, instead of the ACE model, best fitted the data. Based on this, heritability estimates were .81 for astigmatism and .81 for myopia, with a cross-trait genetic correlation of rA = .80, nonshared environmental correlation rE = .89, and a phenotypic correlation of rP = .80. These results are consistent with previous findings in other populations, providing evidence for a similar genetic architecture of these conditions in the multi-ethnic Mexican population.

It has long been assumed that lead glazing technology preceded glassmaking in the Western world and that the technological transfer was from glazes to glass. Here, we present new evidence for the reverse, the indigenous innovation of glassmaking and its transfer to glazes in early Islamic al-Andalus (Spain). Compositional analyses show that Islamic lead glazes from Córdoba are intimately related to a distinct type of high-lead glass, suggesting a connection between the two technologies. The archaeological remains from a pottery workshop indicate that the glazing process initially involved the production of a lead glass and is not linked to earlier Roman or other contemporary glazing technologies. The data also demonstrate that the potters not only used the same materials and techniques but borrowed stylistic and decorative models from glassmaking.

The concept of Design for Additive Manufacturing (DfAM) is gaining popularity along with AM, despite its scopes are not well established. In particular, in the last few years, DfAM methods have been intuitively subdivided into opportunistic and restrictive. This distinction is gaining traction despite a lack of formalization. In this context, the paper investigates experts' understanding of DfAM. In particular, the authors have targeted educators, as the perception of DfAM scopes in the future will likely depend on teachers' view. A bespoke survey has been launched, which has been answer by 100 worldwide-distributed respondents. The gathered data has undergone several analyses, markedly answers to open questions asking for individual definitions of DfAM, and evaluations of the pertinence of meanings and acceptations from the literature. The results show that the main DfAM aspects focused on by first standardization attempts have been targeted, especially products, processes, opportunities and constraints. Beyond opportunistic and restrictive nuances, DfAM different understandings are characterized by different extents of cognitive endeavor, convergence vs. divergence in the design process, theoretical vs. hands on approaches.

This research develops a much-needed approach to the study of glazed ware production in al-Andalus (Muslim Spain and Portugal) during the early Middle Ages. The introduction of glaze to the Iberian Peninsula was a long and complex process involving three waves of technology transfer arriving from the eastern Islamic regions between the ninth and eleventh centuries. In this paper, the main glaze workshops of each technological wave have been characterised in order to understand how the medieval technological transmission took place and how political and economic factors influenced this gradual dissemination.

One of the foundations of product design is the division between production and design. This division manifests as designers aspiring to create fixed iconic archetypes and production replicates endlessly in thousands or millions. Today innovation and technological change are challenging this idea of product design and manufacturing. The evolution of Rapid Prototyping into Additive Manufacturing (AM), is challenging the notion of mass manufacture and consumer value. As AM advances in capability and capacity, the ability to economically manufacture products in low numbers with high degrees of personalisation poses questions of the accepted product development process. Removing the need for dedicated expensive tooling also eliminates the cyclical timescales and commitment to fixed designs that investment in tooling demands. The ability to alter designs arbitrarily, frequently and responsively means that the traditional design process need not be applied and because of this, design processes and practice might be radically different in the future. In this paper, we explore this possible evolution by drawing parallels with principles and development models found in software development.

Rigidity theory is an extraordinary tool to understand glasses. This article demonstrates how this model can help in understanding the link between structure, dynamics, and subtler properties such as drift and aging, in particular, in phase-change materials (PCMs). First, a map of flexible/rigid regions in the Ge-(Sb)-Te system is drawn on the basis of atomistic structures modeled either by ab initio or reverse Monte Carlo techniques. A clear link between the flexible/rigid nature of the glass and its aging behavior is shown through resistivity drift as a function of composition measurements in amorphous GexTe100–x. In the particular case of amorphous GeTe, application of rigidity theory indicates that the average number of mechanical constraints decreases during aging, making the glass less stressed-rigid. Finally, the stability of PCMs also depends on the topology of the materials. The increasing number of constraints in GeTe when doped with C or N results in increased stability of the PCM.

In this paper, a uniplanar RF-MEMS second-order bandpass filter with reconfigurable center frequency is presented. It is based on quarter-wavelength slotline resonators and coplanar waveguide (CPW)-to-slotline multimodal immitance inverters (MIIs), which are reconfigured using RF-MEMS switchable CPW air-bridges (SABs). The filter can be adequately explained and designed using multimodal theory and circuit models. A surface micromachining process on high-resistivity silicon substrate was used to fabricate the filter. Experimental results show frequency reconfiguration from 12 to 13 GHz, maintaining the same relative bandwidth, and insertion losses of 4.6 and 4.7 dB, respectively.

In this paper, micromachined devices for millimeter-wave applications at U- and V-bands are presented. These structures are designed using a rectangular coaxial line built of gold-coated SU-8 photoresist layers, where the coaxial center conductor is suspended in air by stubs. The designs include a stepped coplanar waveguide (CPW)-to-coaxial transition at 63 GHz, with an insertion loss of 0.39 dB at 67.75 GHz and a return loss better than −10 dB across the band of operation between 54.7 and 70.3 GHz. Two filters have been designed; one centered at 42 GHz with a 10% bandwidth, and another at 63 GHz with a 5% bandwidth. Measured insertion losses of 0.77 and 2.59 dB were obtained for these filters, respectively. Measured return loss lower than 13.8 dB over the passband was achieved for both designs. The structures presented in this paper involve a low-cost manufacturing process suitable to produce integrated subsystems at millimeter waves.

This paper proposes the design of tunable dual-band resonators for multi-band multi-standard systems. The main objective is to provide frequency tunability in the second resonance while maintaining the first resonance fixed. To this end, two tunable resonators are proposed: the capacitive-loaded stepped-impedance resonator and the capacitive-loaded hole resonator. The work is divided into two main parts. In the first part, an in-depth analysis of the capacitive-loaded stepped-impedance resonator (SIR) structure is done; it provides analytical closed-form design equations that ease the resonator design in contrast to the several approaches available in the literature to date. The analysis is also particularized to the case of the capacitive-loaded constant-section resonator and extended to the capacitive-loaded hole resonator. In addition, a study of the quality factor in capacitively tuned SIRs is also provided. In the second part, resonators are integrated in three dual-band tunable filters, one based on the capacitive-loaded constant-section resonator, another one on the capacitive-loaded SIR, and finally on the capacitive-loaded hole resonator. Two of these filters demonstrate operation in wireless local-area network frequency bands, with a fixed first band at 2.45 GHz and a second band which can be tuned between 5.75 and 5.25 GHz.

We demonstrate, both experimentally and by computer simulation, that while the metastable face-centered cubic (fcc) phase of Ge-Sb-Te becomes amorphous under hydrostatic compression at about 15 GPa, the stable trigonal phase remains crystalline. We present evidences that the pressure-induced amorphisation phenomenon strongly depends on the concentration of vacancies included in the Ge/Sb sublattice, but is thermally insensitive. Upon higher compression, a body-centered cubic phase is obtained in both cases at around 30 GPa. Upon decompression, the amorphous phase is retained when starting with the fcc phase while the initial structure is recovered when starting with the trigonal phase. We argue that the presence of vacancies and the associated subsequent large atomic displacements lead to nanoscale phase separation and the loss of the initial structure memory in the fcc staring phase of Ge-Sb-Te. We futher compare the amorphous phase obtained via the pressure route with the melt quenched amorphous phase.

The aim of this study was to evaluate the effects on dairy performance and milk fatty acid (FA) composition of (i) supplementation with extruded linseed (EL), (ii) supplementation with synthetic or natural antioxidants, namely vitamin E and plant extracts rich in polyphenols (PERP), (iii) cow breed (Holstein v. Montbéliarde) and (iv) time of milking (morning v. evening). After a 3-week pre-experimental period 24 lactating cows (12 Holstein and 12 Montbéliarde) were divided up into four groups of six cows: the first group received a daily control diet (diet C) based on maize silage. The second group received the same diet supplemented with EL (diet EL, fat level approximately 5% of dietary dry matter (DM)). The third group received the EL diet plus 375 IU/kg diet DM of vitamin E (diet ELE). The fourth group received the ELE diet plus 10 g/kg diet DM of a PERP mixture (diet ELEP). Compared with the diet C, feeding EL-rich diets led to lower concentrations of total saturated FA (SFA) and higher concentrations of stearic and oleic acids, each trans and cis isomer of 18:1 (except c12-18:1), non-conjugated isomers of 18:2, some isomers (c9t11-, c9c11- and t11t13-) of conjugated linoleic acid (CLA), and 18:3n-3. The vitamin E supplementation had no effect on milk yield, milk fat or protein percentage and only moderate effects on milk concentrations of FA (increase in 16:0, decreases in 18:0 and t6/7/8-18:1). The addition of PERP to vitamin E did not modify milk yield or composition and slightly altered milk FA composition (decrease in total saturated FA (SFA) and increase in monounsaturated FA (MUFA)). The minor effects of vitamin E may be partly linked to the fact that no milk fat depression occurred with the EL diet. During both periods the Holstein cows had higher milk production, milk fat and protein yields, and milk percentages of 4:0 and 18:3n-3, and lower percentages of odd-branched chain FA (OBCFA) than the Montbéliarde cows. During the experimental period the Holstein cows had lower percentages of total cis 18:1, and c9,c11-CLA, and higher percentages of 6:0, 8:0, t12-, t16/c14- and t13/14-18:1, and 18:2n-6 than Montbéliarde cows because of several significant interactions between breed and diet. Also, the total SFA percentage was higher for morning than for evening milkings, whereas those of MUFA, total cis 18:1, OBCFA and 18:2n-6 were lower. Extruded linseed supplementation had higher effect on milk FA composition than antioxidants, breed or time of milking.