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Deviations in P300 activity have been implicated in depression and anxiety; however, much of this research has been conducted in adult samples and has primarily examined the association between P300 amplitude and internalizing symptoms between participants. We sought to simultaneously examine the between- and within-subject associations between depression and anxiety symptoms with P300. Self-report and neural data from a flanker task were collected at three timepoints over the course of two years in a large sample of adolescents (n = 490). Blunted P300 was robustly related to elevated between-subject depression. Conversely, elevations in within-subject anxiety were associated with larger P300. Results implicate the P300 as a reliable correlate of between-subjects level depression-related deficits in cognitive functions that is not susceptible to within-subject changes. Additionally, P300 also serves as a correlate of within-subject elevations in youth anxiety symptoms likely reflecting greater hyperarousal at the time of assessment.
Adolescents’ communication with friends increasingly occurs online and research has primarily focused on the quantity rather than the quality of interactions, such as feeling supported or ignored. Since feeling supported or ignored by friends offline affects adolescents’ well- and ill-being, it is essential to understand how these dynamics unfold in online contexts, particularly for adolescents with elevated depressive symptoms, who may be especially sensitive to these experiences. In this preregistered 100-day diary study, 479 adolescents (Mage = 15.98, 54.9% girls; 96.9% Dutch) reported daily on time spent communicating online with friends, their experiences of feeling supported and ignored by friends, and their well- and ill-being. Results showed that time spent communicating online with friends did not relate to adolescents’ well- and ill-being. Feeling supported by friends online resulted in higher well-being and lower ill-being, while feeling ignored by friends online was related to lower well-being and higher ill-being. Adolescents with elevated depressive symptoms experienced intensified effects, both positive and negative, suggesting more vulnerability to everyday online social experiences but also increased benefit from online support. Altogether, this underscores the importance for parents and clinicians to foster open conversations to help adolescents with elevated depressive symptoms navigate their digital social world.
This study examined adolescent–family relationship predictors of adult-era resilience in the face of the COVID pandemic, considering both mental and physical health outcomes. Adolescents (99 female, 85 male; 107 White, 53 African American, 15 mixed race/ethnicity, 9 from other minority groups) were followed from age 18 to 38 utilizing both observational and self-report assessments. After accounting for levels of functioning pre-COVID, adolescents who demonstrated a capacity to handle disagreements without becoming engaged in relatedness-undermining hostile behavior in mother-adolescent dyads went on as adults to experience relatively fewer depressive symptoms and better physical health quality post-COVID onset (Direct β’s = 0.28 and −0.17, respectively). Follow-up analyses suggested these effects were potentially mediated by maternal reports of adult-era quality of the mother-participant relationship, by level of ongoing maternal contact, and by lower levels of loneliness. Evidence was also found that maintaining contact with fathers in adulthood predicted better health outcomes post-pandemic. Results are taken as supporting a systems approach to understanding resilience, as Luthar has suggested, and identifying the mother–adolescent relationship as a potential long-term protective factor well into mid-adulthood.
What becomes of young people who display strong psychopathy traits? By combining cutting-edge research with interviews from over 500 incarcerated youth assessed for psychopathy and involved in serious, violent offenses, this book investigates whether they are destined to persist in crime throughout their lives. Evan McCuish explores not only long-term offending patterns but also psychopathy's influence on relationships, employment, substance use, and mortality. Through this, the text clarifies the meaning of the clinical construct of psychopathy and debunks myths and misconceptions popularised by the true crime genre. This allows readers to more reliably interpret the accuracy of popular culture descriptions of psychopathy. Synthesising over 100 years of research, this book defines psychopathy and contributes new knowledge to the field. It is ideal for students, scholars, and practitioners in psychology, criminology, social work, and law seeking further insight into this intriguing disorder.
The development of psychopathology during childhood and adolescence is complex and likely to follow diverse patterns. Mapping trajectories of psychopathological difficulties may improve our understanding of the nature of emerging, resolving and persistent psychopathology. The purpose of this study is to examine trajectories of psychopathology throughout childhood and adolescence by examining multiple data sources, including questionnaire-based reports of emotional and behavioural difficulties, psychiatric diagnoses and prescribed psychotropic medications.
Methods
Group-based multi-trajectory modelling was used to identify the psychopathological trajectories. This study included 49,361 full-term live-born singleton children born between 1996 and 2003, recruited into the Danish National Birth Cohort. Strengths and Difficulties Questionnaire data were collected when the children/adolescents were 7, 11 and 18 years old. Annual information about psychiatric diagnoses and redeemed prescriptions for psychotropic medication was retrieved from nationwide registries between the ages of 1 and 18. We included six predefined dimensions to identify the trajectories: internalizing behavioural problems, externalizing behavioural problems, neurodevelopmental diagnoses, affective diagnoses, mixed psychiatric diagnoses and psychotropic medications.
Results
Six distinct trajectory groups were identified for both boys and girls. Approximately 6% of the boys and 8% of the girls receive the bulk of the psychiatric diagnoses and psychotropic medications. We found no support for ‘pure’ internalizing or externalizing patterns in any identified trajectory, as problems in one dimension often indicated the presence of problems in another dimension.
Conclusions
Our results demonstrate substantial psychiatric comorbidity and add new insights to the understanding of child and adolescent well-being and the complex patterns of developmental psychopathology.
Exposure to major life stressors and aberrant brain functioning have been related to anxiety and depression in adolescence. However, whether these associations differ based on the specific characteristics of the stressors and/or brain functional networks remains unclear.
Methods
In a longitudinal sample of adolescents enriched for anxiety and depressive disorders, we examined cumulative lifetime stressor frequency and severity of five stressor characteristics: physical danger, interpersonal loss, humiliation, entrapment, and role change/disruption. Anxiety and depression symptoms were assessed at three time points: baseline, 6-month, and 12-month follow-ups. Linear mixed-effect models tested if lifetime frequency and severity of these stressor characteristics were associated with anxiety and depression symptoms across the three time points. We also identified whole-brain resting-state functional connectivity (RSFC) features linked to the predictive stressor characteristics and examined their associations with anxiety and depression symptoms across time.
Results
Controlling for all other stressor characteristics and covariates, lifetime frequency and severity of humiliation and entrapment predicted greater anxiety and depression symptoms across the three time points. After additionally accounting for co-occurring depression and anxiety symptoms, only entrapment frequency and severity remained significant. More negative RSFC between the frontoparietal network and the left cerebellum were linked to greater entrapment severity at baseline, and associated with greater anxiety and depression symptoms across time.
Conclusions
Our study highlights lifetime exposures to humiliation and entrapment as central stressor characteristics linked to adolescent internalizing symptoms. Our results also suggest that frontoparietal–left cerebellar connectivity may be a stress-sensitive marker of adolescent internalizing problems over time.
Negative urgency is a transdiagnostic risk factor for a plethora of mental disorders. Internalizing symptoms are embedded in theories of negative urgency, yet we know little regarding how developmental changes in each coincide, and if changes in one predict changes in the other across middle adolescence. This study filled these voids in the literature, with N = 754 (52% female) community-recruited youth from the National Consortium on Alcohol NeuroDevelopment in Adolescence (NCANDA) study reporting internalizing symptoms and negative urgency annually. Negative urgency and internalizing symptoms were highly correlated at the between-person level, and between-person correlations were nearly double in size within male versus female adolescents. At the within-person level, changes in negative urgency and internalizing symptoms co-occurred across ages 14–18 but not age 13. Age 14 within-person changes in negative urgency prospectively predicted age 15 within-person changes in internalizing symptoms, and this effect was nearly double in size within female versus male adolescents. Findings held when accounting for externalizing symptoms, other impulsive personality traits, parenting, and school transitions. Results indicate that relations between negative urgency and internalizing symptoms were demonstrated across and within adolescents, with time-varying changes in negative urgency at age 14 being particularly impactful in terms of future internalizing symptoms.
Adolescence is characterized by heightened sensitivity to social belonging, making loneliness prevalent and consequential for youth. Maladaptive personality traits may further exacerbate loneliness. In this preregistered 14-day Ecological Momentary Assessment study, we examined loneliness across social contexts and timescales in relation to maladaptive personality traits among N = 294 adolescents aged 12–21 years (Mage = 17.5, SD = 2.64; 58.5% female; 86.73% born in Germany). Participants answered 27,503 of 32,340 momentary prompts, indicating high compliance (85.1%). Loneliness (βmomentary = 0.51; βdaily = 0.67) was higher when participants were alone, yet only the presence of close others (e.g., friends) – not weaker ties (e.g., classmates) – reduced loneliness (β = –0.39 to –0.62). Youth who were alone more frequently did not report higher overall loneliness. Maladaptive personality traits were associated with higher (βmomentary = 0.32; βend-of-day = 0.40) and more variable (βmomentary = 0.31; βend-of-day = 0.34) loneliness but amplified the effect of being alone on loneliness only on the between-person level (β = –1.13). Exploratory analyses indicated that social satisfaction partially mediated the association (β = 0.50). These findings underscore the importance of both structural and qualitative aspects of social environments, as well as personality-related vulnerabilities, to better understand loneliness dynamics in youth.
Drug use disorder (DUD) clusters in families due partly to shared environment, including sibling influences. Low academic achievement (AA) in adolescence increases DUD risk. This study examined whether low AA in an older sibling causally increases DUD risk in younger siblings.
Methods
We studied all Swedish full sibling pairs (n = 309,666) born 1972–1985 and ≤ 5 years apart. Older sibling AA was assessed at age 16. Using Month-of-Birth (MoB) as an instrument, we conducted instrumental variable (IV) analyses and propensity score (PS) models to evaluate the causal impact of older sibling AA on younger sibling DUD risk, assessed by DUD registration in national medical, criminal, or pharmacy registries.
Results
Older sibling AA significantly predicted younger sibling DUD risk across models. Beta coefficients (±95% CI) were 2.04 (1.97–2.12) in raw analysis, 1.88 (0.74–3.02) in IV, and 1.26 (1.17–1.34) in PS models. Together with the strong first-stage association, the IV estimates remain positive under small departures from the ideal identifying assumptions. Effect sizes declined with increasing sibling age differences (p = 0.036 for IV; p < 0.0001 for PS) and were strongest in male–male pairs (IV: 4.01 [1.42–6.61]; PS: 1.74 [1.55–1.93]). Mediation by older sibling DUD was modest.
Conclusions
Findings from two causal inference approaches support a largely causal link between low AA in an older sibling and increased DUD risk in younger siblings. Stronger effects in close-aged and male–male pairs further support this conclusion. Interventions to improve AA in older siblings may yield indirect preventive benefits for younger siblings.
Understanding the structure of citizens’ trust in state institutions is essential for assessing its role in sustaining healthy, legitimate democracies. While research has revealed a puzzling duality in institutional trust among adults – being subdomain-specific yet unidimensionally ordered – little is known about how these patterns originate and develop. This study integrates evaluative and socialisation perspectives to investigate the development of institutional trust structures during adolescence. Using longitudinal data from the Dutch Adolescent Panel on Democratic Values (2018–2022), tracking adolescents from ages 12 to 16 (N = 1,092 individuals), we employ confirmatory factor analysis and Mokken scaling to assess how the subdomain-specific and hierarchical features of institutional trust evolve across time and cognitive resources (ie school track and political sophistication). Our results support an early macro-level socialisation account of trust development, showing that adolescents as young as 12 already distinguish between order and representative institutions and consistently rank them in ways that mirror adult trust structures. However, among adolescents with higher cognitive resources, these structures become more volatile in mid-to-late adolescence, suggesting the gradual onset of more individualised, evaluative trust judgements. Taken together, the findings show a dual process of institutional trust development, suggesting that early cultural imprinting provides a baseline blueprint of institutional trust, which may later be recalibrated by more sophisticated citizens through individual evaluation.
Elizabeth Bowen’s fiction is full of girls; in nearly all her work, she focuses on the act of maturing through adolescence to early adulthood. The experience of girlhood among Bowen’s characters maps onto the generic characteristics of her truncated, ambiguous Bildungsromane, all of which subvert expectations and resist satisfying maturation. Her novels focus on figures experiencing historical and emotional arrest, and her adolescent girls often remain in moments of developmental or social suspension. This essay traces girlhood and adolescence in abeyance in Bowen’s short fiction, and in novels ranging from The Hotel to The Death of the Heart to The Little Girls.
The current chapter focuses on the development of adolescents’ relationships with parents, friends, and romantic partners, and their role in youth’s psychosocial adjustment. The chapter describes how relationships with parents in adolescence go through a period of transition toward a more egalitarian and reciprocal relationship, with temporary decreases in connectedness and increases in conflict in the process. Adolescents’ relationships with friends become more supportive and acquire a more optimal balance between intimacy and respect for each other’s individual needs over the course of adolescence. Positive experiences of adolescents in relationships with parents and friends predict healthy romantic functioning and satisfaction later in adolescence and emerging adulthood. Romantic involvement and relationship quality typically progresses towards increased attachment and intimacy functions in late adolescence and young adulthood. Satisfactory romantic relationships and a healthy sexual development tend to go hand-in-hand. High-quality relationships with parents, friends, and romantic partners are typically associated with positive socioemotional outcomes.
Adolescence is a sensitive period for social and neural development. Empathic growth during adolescence has been linked to improved prosocial behavior in adulthood. This study examined how adolescent empathy relates to adulthood neural responses to rejection.
Method:
Participants (N = 77; 42 females, 52% White) were drawn from a demographically diverse community sample and assessed annually from ages 13 to 21. Each year, participants’ empathic support provision toward a close friend was evaluated during an observationally coded support task. At approximately age 24, participants completed the Cyberball social exclusion paradigm while undergoing functional magnetic resonance imaging (fMRI).
Results:
Whole-brain exploratory analyses revealed that greater empathic support provision during adolescence was associated with reduced activation in the subgenual anterior cingulate cortex (sACC) during social exclusion in early adulthood (Cohen’s d = 0.12), suggesting a contribution of empathy provision to rejection-related neural responses later in life. The effect was not driven by felt distress during social exclusion, indicating that adolescent empathic support provision is potentially associated with neural responses to social exclusion independent of subjective distress.
Conclusion:
These findings underscore the long-term links of empathy to adult social processes and may inform interventions aimed at enhancing interpersonal functioning and resilience.
Parental alcohol supply in early childhood may increase the risk of alcohol use in late adolescence. This study examined its longitudinal impact and the distinct roles of mothers’ and fathers’ drinking.
Methods
We studied 1,891 mother–child pairs from the Czech European Longitudinal Study of Pregnancy and Childhood. Mothers reported parental alcohol supply at ages 3, 5, 7, and 11 years, while adolescent alcohol use was reported by mothers, pediatricians, and youth at ages 18 and 19 years. Structural equation modeling assessed the longitudinal link between early alcohol supply (three classes: none, occasional, and frequent) and adolescent alcohol use, accounting for parental drinking and covariates, including the child’s sex, mother’s education, and family structure.
Results
Alcohol supply began in early childhood, with 14% of children exposed by age 3 and around 20% by age 11. By age 19, one-third of individuals reported frequent alcohol use. Adolescents’ alcohol use was associated with concurrent mothers’, but not fathers’ alcohol use (β = .24, p < .001). Early alcohol supply predicted higher adolescent use for both occasional (β = .14, p = .041) and frequent (β = .22, p = .005) classes. Mothers’ and fathers’ alcohol use at 6 months was associated with frequent alcohol supply, and fathers’ alcohol use was also associated with occasional alcohol supply. Significant indirect effects were found from early parental drinking to adolescent use via these classes.
Conclusions
Public health messaging should emphasize the risks of early alcohol consumption, including its potential harm to the developing brain.
Adolescence represents a pivotal neurodevelopmental period marked by escalating anxiety symptoms and heightened approach motivations. Although anxiety is typically linked to avoidance, concurrent shifts in motivational systems and neurocircuitry may alter its behavioral and neural expression, shaping developmental trajectories and treatment response. This study investigated how approach motivations (Behavioral Activation System; BAS) interact with anxiety to influence behavior and brain function in N = 121 adolescents (ages 9–13; 44% girls; 33.1% White, 22.3% Latino, 19.8% Asian, 14.9% Black, 9.9% Mixed Race). Participants completed a decision-making task and resting-state fMRI. Dimensional analyses examined joint effects of anxiety and BAS on risk-taking behaviors, task-evoked neural activity and connectivity, and intrinsic connectivity at rest. Higher anxiety was associated with risk aversion and inhibition when BAS was low, but with risk-taking and impulsivity when BAS was high (risk-taking: β = 0.25, p = .012; inhibitory control: β = 0.13, p < .001). During risk-taking, anxiety and BAS showed interactive effects on striatal (β = −0.10, p = .006) and amygdala (β = 0.10, p = .005) activity alongside distinct effects on prefrontal–subcortical connectivity (β = −0.30, p = .014; β = 0.17, p = .01). Higher BAS was associated with stronger intrinsic prefrontal–striatal connectivity (β = 0.23, p = .012), while anxiety showed no significant resting-state effects. Findings underscore the role of reward-related systems in adolescent anxiety and support developmentally informed, personalized intervention strategies.
What is the mechanism by which a linguistic change advances across successive generations of speakers? We explore this question by using the model of incrementation provided in Labov 2001 and analyzing six current changes in English. Extending Labov's focus on recent and vigorous phonological changes, we target ongoing morphosyntactic(-semantic) and discourse-pragmatic changes. Our results provide a striking validation of the incrementation model, confirming its value as a key to understanding the evolution of linguistic systems. However, although our findings reveal the predicted peak in the apparent-time progress of a change and corroborate the female tendency to lead innovation, there is no absolute contrast between men and women with respect to incrementation. Instead, quantitative differences in the social embedding of linguistic change correlate with the rate of the change in the speech community.
Low socioeconomic status (SES) is linked to pubertal development, mental health issues, and academic performance. However, the role of early pubertal development in the link between low SES and mental health and academic outcomes is unclear. Using longitudinal data from the ABCD Study (9–10 years at baseline, N = 9,848, 52.2% males) across four time points, we examined associations between household and neighborhood disadvantage, pubertal development, and mental health and academic achievement. Greater household and neighborhood disadvantage were associated with more advanced pubertal status at baseline in both males and females. Among females, higher pubertal status at baseline mediated the association between lower household income and neighborhood disadvantage with greater mental health problems and poorer school performance. Additionally, slower pubertal tempo attenuated the relationship between neighborhood disadvantage and these outcomes in females. These findings underscore the importance of considering both household and neighborhood contexts in shaping adolescent development and highlight pubertal development as a potential pathway underlying socioeconomic disparities in mental health and academic achievement.
Friends and popular peers are important sources of influence across the transition into adolescence. The present study examines the assertion that the magnitude of influence from friends and popularity-based norms varies across behavioral domains. Participants were 543 (268 girls, 275 boys) students from 29 5th–8th grade (ages 10 to 14) classrooms in three Lithuanian public middle schools. Most were ethnic Lithuanians. Self-reports of socioemotional adjustment, including emotional problems, lack of emotional clarity, problem behaviors, social media use, and weight concerns, were collected in the fall and winter of a single academic year, approximately three months apart. Popularity and academic achievement were assessed through peer nominations. Top-ranked best friends were identified from outgoing nominations. Status-based norms, calculated separately for each socioemotional adjustment variable in the fall (Time 1), represented popularity-weighted classroom averages. Results from longitudinal Group Actor-Partner Interdependence Model analyses indicated that best friends and status-based norms exerted differing amounts of influence over different behaviors. When both were included in the same model (with shared effects removed), best friends influenced emotional problems, lack of emotional clarity, and problem behaviors. Among older adolescents, best friends also influenced academic achievement. Status-based norms influenced social media use and, among older adolescents, weight concerns.
Neurodevelopmental models regard impulsivity as a central risk factor for adolescent substance use. However, the practical utility of impulsivity in predicting substance use is complicated by variability among measures that encompass multiple methods and theoretical domains. Prior research has been constrained by cross-sectional designs, small sample sizes, and/or the use of a narrow subset of impulsivity measures.
Method
Leveraging the ABCD dataset (n = 11,868), we identified and replicated correlations among impulsivity measures and assessed their prospective longitudinal and concurrent predictive utility regarding adolescent substance use outcomes before 15 years old. We then used simulation to inform how associations between impulsivity and substance use vary across sampling strategies (population vs. high-risk cohorts) and sample sizes.
Findings
Correlations between questionnaire and behavioral measures of impulsivity were small, and questionnaires significantly outperformed behavioral measures in predicting substance use initiation, largely due to the contribution of the CBCL externalizing scale. Predictions of substance use based on impulsivity were statistically detectable but small according to clinical standards (AUCs 0.6–0.76), exhibiting sensitivity to sample size and base rate of substance use, and thus, poor absolute predictive performance. Large samples (n > 1,000) were needed to achieve adequate power for impulsivity measures to predict substance use initiation.
Conclusion
These results support a significant but small contribution of impulsivity in predicting the onset of early adolescent substance use, indicating that these factors alone are insufficient for clinically deployable prediction. In community samples, large sample sizes are needed for reproducible impulsivity prediction of adolescent substance use.
Depression is often comorbid with alcohol use problems, and sex differences may further complicate this interplay.
Methods
We conducted a longitudinal study using a large European adolescent cohort assessed at ages 14 (baseline, BL), 16 (follow-up 1, FU1), 19 (follow-up 2, FU2), and 23 (follow-up 3, FU3). Depression and alcohol use were measured using standardized behavioral scales. Cross-lagged analysis, improved Mendelian randomization (MR) analysis, and mediation analysis were conducted to infer the causal interplay.
Results
2110 adolescents were included at baseline (49% male). Depression and alcohol consumption demonstrated a significant positive correlation (rBL = 0.094, pBL = 1.58E-05, 95% CI = [0.052, 0.137]), which gradually diminished over time and eventually became significantly negative. Depression and alcohol use problems remained strongly correlated across three timepoints (r > 0.074, p < 6.76E-03). Cross-lagged analysis suggested that depression predicted future alcohol use problems: βBL-FU1 = 0.058, p = 0.021, 95% CI = [0.009, 0.108]; βFU2-FU3 = 0.142, p = 8.34E-07, 95% CI = [0.113, 0.263]. MR analyses confirmed this causal interplay (rmean = 0.043, longitudinal ppermuation < 0.001). Interestingly, MR analyses also indicated that alcohol consumption might alleviate depression (rmean = −0.022, longitudinal ppermutation = 0.043), particularly in females at FU3, of which the anxiety status and the personality trait neuroticism largely mediated the effect. These findings were validated in an independent matched sample (N = 562) from Human Connectome Project.
Conclusions
Depression may predict future alcohol use problems, whereas moderate alcohol consumption might alleviate depressive symptoms, especially in females.