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In the first decades of the twentieth century, the concept of “direct action” emerged as a major presence in radical politics. In the years following World War I, opponents of war and militarism reshaped that concept. They insisted upon its nonviolent character, they specified how direct action might be used to oppose war, they distinguished direct action from Bolshevism and social democracy, they imagined direct action as a key contributor to a future nonviolent revolution, and they drew upon contemporary struggles from the Ruhr, to Samoa, to India to justify their political claims. The radicals who shared these debates were linked by an energetic transnational network, spanning the War Resisters’ International and the International Antimilitarist Bureau. This article recovers this network, traces the key intellectual contributions, and argues for their significance. It aims to contribute to the intellectual histories of direct action and of nonviolence and to draw attention to previously submerged debates of the radical interwar left.
To evaluate clinical outcomes in patients with uncomplicated β-hemolytic Streptococcus spp. bloodstream infections (BSI) transitioned to oral antimicrobial therapy (OAT) compared with those that remain on intravenous antimicrobial therapy.
Design:
Retrospective cohort study.
Setting:
Tertiary academic hospital.
Methods:
This retrospective cohort study included adult patients hospitalized between 1/1/2013 and 12/31/2019 diagnosed with uBSI due to β-hemolytic streptococci. Patients were excluded if BSI was due to endovascular, central nervous system, or bone/joint infection or patient was immunosuppressed or died within 72 hours of identification of BSI. We compared outcomes including: 30-day mortality, antimicrobial therapy, BSI relapse, 30-day rehospitalization, adverse drug events, and reversion to IV therapy. Fisher’s exact test was used for categorical variables; Mann – Whitney test and Independent T-test for continuous variables.
Results:
232 BSIs were included. OAT was used in 152 (65%). Cohort demographics were similar. Mortality was also similar between cohorts (2% vs 6% P = .13). Hospital length of stay was shorter in the OAT cohort with a median of 5 days (interquartile range 4.00, 8.00) versus 8 (5.00, 16.00) in the IV group (P < .0001). Patients transitioned to OAT were more likely to finish antibiotics outpatient (93% vs 62% P < .001).
Conclusion:
For β-hemolytic Streptococcus uBSI, OAT was associated with decreased length of stay without adverse clinical outcomes. Opportunities exist to modify clinical management of uBSI.
Number systems are shared social technologies. They are heterogeneous, differing along dimensions of modality, base, and marking. These characteristics impart differential advantages depending on purpose and context, which explains why most cultures employ multiple number systems simultaneously. Number systems are embedded in patterns of complementarity involving both human and physical capital. Viewing number systems this way allows us to apply economic insights about production, cost, and technology to things often regarded as purely abstract cognitive conventions. Combining these insights with the literature on 4E cognition shows how concrete economic factors can shape key aspects of how humans think.
We strengthen known results on Diophantine approximation with restricted denominators by presenting a new quantitative Schmidt-type theorem that applies to denominators growing much more slowly than in previous works. In particular, we can handle sequences of denominators with polynomial growth and Rajchmann measures exhibiting arbitrary slow decay, allowing several applications. For instance, our results yield non-trivial lower bounds on the Hausdorff dimensions of intersections of two sets of inhomogeneously well-approximable numbers (each with restricted denominators) and enable the construction of Salem subsets of well-approximable numbers of arbitrary Hausdorff dimension.
Implantable haemodynamic monitors allow remote monitoring of Fontan circulation. We report unique opportunities and challenges related to device use in rural, high-altitude regions.
Objectives:
Assess the performance of implantable haemodynamic monitor in Fontan circulation and identify potential sources of measurement discrepancy defined as non-physiological, negative, or significantly lower reading than baseline.
Methods:
We performed a retrospective review of patients who underwent implantable haemodynamic monitor implantation from September 2021 to April 2024 (n = 17) at our centre (∼1,000 feet above sea level; ASL) and identified those with sensor discrepancies.
Results:
During a mean follow-up duration of 26 months (range 13–44 months), there were no procedure-related complications, thromboembolism, or device displacement. Ten patients lived in rural, higher-altitude regions (average altitude 5100 feet above sea level, average distance from centre ∼160 miles, range = 100–400 miles). Challenges in remote monitoring included unreliable home-internet connection, non-compliance, and difficulty performing device recalibration at patient’s home altitude. Sensor discrepancies were noted in 7 patients (41%), of whom 6 (86%) lived remotely. Manual review of the waveforms identified sources of discrepancy, including misinterpretation of the non-pulsatile pressure waveform (n = 3), offset due to change in hospital-interrogation unit (n = 4), and sensor drift (n = 1). Altitude change did not directly affect sensor performance. We were able to apply corrective interventions in 4/7 sensors, including Fontan-specific settings (overriding pulsatility), and back-end recalibration, which were effective in improving device accuracy.
Conclusions:
Implantable haemodynamic monitors are a promising tool for monitoring Fontan circulation but may require modified settings and careful attention to potential interpretation errors. Home monitoring remains challenging for rural, high-altitude residents with limited resources.
Biologically inspired aero/hydrodynamics attracts considerable interest because of promising efficiency and manoeuvring capabilities. Yet, the influence that external perturbations, typical of realistic environments, can have over the flow physics and aerodynamic performance remains a scarcely investigated issue. In this work, we focus on the impact of free stream turbulence (FST) on the aerodynamics of a flapping wing with a prescribed (heaving and pitching) motion at a chord-based Reynolds number of 1000. The problem is tackled by means of direct numerical simulations using an immersed boundary method and a synthetic turbulence generator. The effect of two key parameters, i.e. the turbulence intensity and integral length scale of FST, is described by characterising the phase- and spanwise-averaged flows and aerodynamic coefficients. In particular, we show how FST effectively enhances the dissipation of the vortices generated by the flapping wing once they are sufficiently downstream of the leading edge. The net (i.e. time-averaged) thrust is found to be marginally sensitive to the presence of FST, whereas the characteristic aerodynamic fluctuations appear to scale linearly with the turbulence intensity and sublinearly with the integral length scale. Moreover, we reveal a simple mechanism where FST triggers the leading-edge vortex breakup, which in turns provides the main source of aerodynamic disturbances experienced by the wing. Finally, we show how the frequency spectra of the aerodynamic fluctuations are governed by the characteristic time scales involved in the problem.
A set of 710 accessions of global durum wheat panel was obtained from the International Centre for Agricultural Research in Dryland Areas (ICARDA) and evaluated for variability in 32 agro-morphological traits at the ICAR-Indian Institute of Wheat and Barley Research, Karnal, India, during 2021–22 and 2022–23. The accessions were grouped based on the type of breeding material and geographical origin, and the Shannon–Wiener diversity index (H′) was calculated for each trait as well as each group. The H′ values ranged from 0.02 (grain crease) to 1.27 (wax of ear) with an overall mean of 0.63, when considering the entire set as a single group. Landraces exhibited higher variability (H′ = 0.64) as compared to released cultivars and evolutionary pre-breeding population lines (H′ = 0.55). Furthermore, accessions originating from West Asia exhibited the highest variability (H′ = 0.63). Traits such as coleoptile colour, plant growth habit, auricle colour and pubescence, flag leaf attitude, ear shape, presence or absence of awns, awns colour and attitude, glumes shape and pubescence, beak length, peduncle attitude, grain phenol colour, grain germ width and brush hair length were found suitable for distinguishing the present durum accessions due to their higher frequency distribution and Shannon–Wiener diversity index values. A core set of 13 accessions was developed using the programme Power Core. These accessions represent the overall variability of the entire set and can therefore serve as a potential source of new genes/alleles for the genetic enhancement of durum wheat. This durum panel may also serve as a valuable reference collection for global researchers in the characterization of durum wheat accessions.
Interactions between shock waves and gas bubbles in a liquid can lead to bubble collapse and high-speed liquid jet formation, relevant to biomedical applications such as shock wave lithotripsy and targeted drug delivery. This study reveals a complex interplay between acceleration-induced instabilities that drive jet formation and radial accelerations causing overall bubble collapse under shock wave pressure. Using high-speed synchrotron X-ray phase contrast imaging, the dynamics of micrometre-sized air bubbles interacting with laser-induced underwater shock waves are visualised. These images offer full optical access to phase discontinuities along the X-ray path, including jet formation, its propagation inside the bubble, and penetration through the distal side. Jet formation from laser-induced shock waves is suggested to be an acceleration-driven process. A model predicting jet speed based on the perturbation growth rate of a single-mode Richtmyer–Meshkov instability shows good agreement with experimental data, despite uncertainties in the jet-driving mechanisms. The jet initially follows a linear growth phase, transitioning into a nonlinear regime as it evolves. To capture this transition, a heuristic model bridging the linear and nonlinear growth phases is introduced, also approximating jet shape as a single-mode instability, again matching experimental observations. Upon piercing the distal bubble surface, jets can entrain gas and form a toroidal secondary bubble. Linear scaling laws are identified for the pinch-off time and volume of the ejected bubble relative to the jet’s Weber number, characterising the balance of inertia and surface tension. At low speeds, jets destabilise due to capillary effects, resulting in ligament pinch-off.
Genebanks worldwide play a crucial role in the long-term conservation and accessibility of wide diversity of plant genetic resources (PGR). These resources are essential for addressing current and future challenges related to climate change and biodiversity loss, thereby contributing to agricultural production and sustainability. Enhancing the efficiency of genebanks requires implementing a quality management system that ensures data transparency, as well as the documentation and standardization of processes. This study proposes a set of 10 mandatory and 38 optional genebank metrics specifically designed for collections of orthodox seeds. These metrics define a set of basic parameters that are easy to calculate and collectively serve as a valuable tool for improving genebank management, enhancing performance, fostering transparency and promoting collaborations among institutions. Fourteen institutions engaged in the long-term conservation of PGR were consulted in the development of the proposed metrics. This work lays the foundation for the establishment of a widely accepted set of genebank metrics within the global genebank community. Further research and iterative development are necessary to formulate comprehensive metrics applicable to other ex situ conservation methods (such as cryopreservation, in vitro and field conservation) as well as in situ conservation strategies (including genetic reserves and on-farm conservation).
While conducting archaeological survey to document the large prehistoric canal systems in the central portion of the Tehuacán Valley, investigators recorded a mound and plaza complex that includes what appears to be an effigy mound in the shape of a scorpion. Large quantities of ceramics, including surface-decorated and polychromes, indicate a Late Classic and Postclassic occupation. The site is interpreted as being part of an intensive agricultural system as it appears centrally located in the context of highly developed agricultural and irrigation infrastructure. For the reasons described, we interpret this ca. 60 meter scorpion effigy mound as an intentional feature with possible astronomical alignments. It is hypothesized as being part of a local civic/ceremonial complex with the possible use/function of observing the summer and winter solstices. If so, it provides an insight into the integration of calendrical ritual with the surrounding complex system of fields and irrigation canals. Admittedly, these observations and explanations are relatively subjective. However, we consider them to be persuasive when the evidence is considered in its entirety.
This study aimed to review the incidence, outcomes and treatment of delayed facial nerve palsy (DFP) following otological surgery.
Methods
MEDLINE, Pubmed, Embase and The Cochrane Central Register of Controlled Trials were searched up to 10 May 2024. A systematic review was conducted per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines of studies reporting on DFP following otological surgery. The risk of bias was assessed using the JBI critical appraisal tools.
Results
Forty-nine articles were included with 201 instances of DFP following 24,917 operations from 1967 to 2021. The mean day of onset post-operatively was 8.4. 93 per cent of episodes fully recovered, with most cases taking between eight days and one month to recover.
Conclusion
Many theories of the pathogenesis of DFP exist. It is rare and has an excellent prognosis following treatment with corticosteroids with or without anti-viral therapy.
Catches of yellowjackets (Hymenoptera: Vespidae) in traps baited with proteinaceous baits or a heptyl butyrate–based synthetic chemical lure in British Columbia, Canada, and Rio Negro, Argentina, differed among species. In British Columbia, western yellowjackets, Vespula pensylvanica (Saussure), responded preferentially to traps baited with rotisserie chicken (Galliformes: Phasianidae) over canned chicken or canned sardines (Clupeiformes, Clupeoidei), but the synthetic chemical lure was more attractive than rotisserie chicken. Counterintuitively, when rotisserie chicken and the synthetic chemical lure were combined, catches were reduced. In British Columbia, more German yellowjackets, V. germanica Fabricius, were caught in traps baited with rotisserie chicken than with canned chicken, and in Argentina, both German and common, V. vulgaris Linnaeus, yellowjackets preferred sardine-flavoured cat (Carnivora: Felidae) food over the synthetic chemical lure. In British Columbia, northern yellowjackets, V. alascensis (Packard), showed no preference among three types of chicken or between rotisserie chicken and canned sardines. When rotisserie chicken and the synthetic chemical lure were combined, catches of both northern and German yellowjackets were no higher than when traps were baited with rotisserie chicken alone. Resolution of the differential roles of red meat-, poultry-, and fish-based baits, as well as improvement of synthetic chemical lures, would be facilitated by identification of bioactive semiochemicals.
We prove that P-points (even strong P-points) and Gruff ultrafilters exist in any forcing extension obtained by adding fewer than $\aleph _{\omega } $-many random reals to a model of CH.These results improve and correct previous theorems that can be found in the literature.
Environmental outcomes can be shaped by underlying politics. This study investigates whether pre-determined election timings affect these outcomes by combining electoral data with remote sensing data on crop burning, forest fires, slash-and-burn activity, and tree cover for 28 major states (covering approximately 3800 assembly constituencies) in India from 2008 to 2019. Analysing 71 elections during this period reveals evidence of the presence of electoral cycles in environmental outcomes, with non-election years experiencing higher levels of environmentally harmful activities compared to election years. These cycles are more pronounced when the incumbent’s party wins without a supermajority in state elections. The study further shows that specific factors, such as high-yield crop varieties, poverty levels, and Scheduled Tribe population proportions, also shape these environmental outcomes across the electoral cycle.
The Indo-Gangetic plains of India have been experiencing erratic weather and unpredictable rainfall patterns for the past 5 years, the average annual rainfall being 1200–1500 mm in the cropping season. Millets are generally grown in this region during the rainy season but environmental fluctuations result in heavy yield penalties in proso millet. Proso millet is one of the preferred crops of this region; however, it is very prone to yield loss due to flooding. Stability studies were conducted to investigate growing proso millet as a catch crop during summer (February–May) as it is a short-duration crop and can fit well in the existing cropping system. This study aims to determine the effect of genotype, environment and their interaction on grain yield and to identify more stable proso millet genotypes suitable for cultivation in the summer season. In total, 63 genotypes were evaluated for various agro-morphological traits for two summer and one kharif seasons. Stability analysis using a GGE biplot revealed that the proso millet performed better in the summer season than in the kharif season. This study has identified summer season as the most ideal environment for multilocation testing of wining genotypes RAU PM- 17, RAU PM-22, RAU PM-35, RAU PM-54, BR-7, TNAU-202 and TNAU-164 which has high stability for the summer season and can be used in breeding programmes as donor parents for traits like grain yield, 1000 grain weight, panicle length and number of productive tillers.