The National Film Board documentary Bing Bang Boom (1969) depicts Canadian composer R. Murray Schafer (1933–2021) teaching seventh-grade students in a suburban public school in Scarborough, Ontario. A close study of the film informs the larger trajectory of the composer’s previous and later writings and compositions over the next several decades, while a deeper dive into archival materials and concurrent productions from Canada’s National Film Board (NFB) illuminates the organisation’s strategy of nation-building at a crucial moment in the country’s history. Together, Schafer and the NFB illuminate Canada’s problematic relationship to Indigenous peoples, places and sounds.

This preregistered study replicates and extends studies concerning emotional response to wartime rally speeches and applies it to U.S. President Donald Trump’s first national address regarding the COVID-19 pandemic on March 11, 2020. We experimentally test the effect of a micro-expression (ME) by Trump associated with appraised threat on change in participant self-reported distress, sadness, anger, affinity, and reassurance while controlling for followership. We find that polarization is perpetuated in emotional response to the address which focused on portraying the COVID-19 threat as being of Chinese provenance. We also find a significant, albeit slight, effect by Trump’s ME on self-reported sadness, suggesting that this facial behavior served did not diminish his speech, instead serving as a form of nonverbal punctuation. Further exploration of participant response using the Linguistic Inventory and Word Count software reinforces and extends these findings.

In the past two decades, the synergistic relationship among task-based language teaching (TBLT), instructed second language acquisition, and computer-assisted language learning has gained increasing interest.Technology-mediated TBLT combines these three research domains by integrating the use of technology with task-based approaches for second language (L2) learning purposes. Since the emergence of this framework, empirical studies have increasingly explored the incorporation of tasks with technology-mediated settings for L2 learning and teaching purposes. To understand the methodological characteristics of technology-mediated TBLT research to date, we conducted a systematic search and reviewed 254 technology-mediated TBLT studies published between 2000 and 2022 in peer-reviewed journals and book chapters. These studies were coded for methodological features, research foci, and types of technology. We further examined the role of technologies in task performance to identify their effectiveness in creating authentic tasks. The findings revealed that technology-mediated TBLT research investigated a rather limited scope of contexts, learner groups, and linguistic features, with little attention paid to evaluating the quality of task outcomes. The types of technology used were skewed toward computer-mediated communication. The results also showed that studies examined various interactional features, and the majority reported both quantitative and qualitative data. Furthermore, technologies were integrated into task design to create meaningful language use contexts. Based on these findings, we share suggestions for future technology-mediated TBLT research.

Disasters can cause great physical and financial damage to pet owners in developing countries. These effects lead to severe psychological side effects on individuals and families. With the tendency of families to keep pets in these countries, many challenges have arisen regarding how to manage these pets before, during, and after disasters. Therefore, mitigation, prevention, and preparedness measures for these families should be prioritized in the disaster management cycle to minimize psychological effects such as posttraumatic stress disorder (PTSD) after losing pets.

Methionine (Met) can activate the mechanistic target of rapamycin (mTOR) to promote milk synthesis in mammary epithelial cells. However, it is largely unknown which G protein-coupled receptor can mediate the stimulation of Met on mTOR activation. In this study, we employed transcriptome sequencing to analyse which G protein-coupled receptors were associated with the role of Met and further used gene function study approaches to explore the role of G protein-coupled receptor 183 (GPR183) in Met stimulation on mTOR activation in HC11 cells. We identified nine G protein-coupled receptors including GPR183 whose expression levels were upregulated by Met treatment through RNA sequencing and subsequent quantitative real-time PCR analysis. Using GPR183 knockdown and overexpression technology, we demonstrate that GPR183 is a positive regulator of milk protein and fat synthesis and proliferation of HC11 cells. Met affected GPR183 expression in a dose-dependent manner, and GPR183 mediated the stimulation of Met (0·6 mM) on milk protein and fat synthesis, cell proliferation and mTOR phosphorylation and mRNA expression. The inhibition of phosphoinositide 3-kinase blocked the phosphorylation of mTOR and AKT stimulated by GPR183 activation. In summary, through RNA sequencing and gene function study, we uncover that GPR183 is a key mediator for Met to activate the phosphoinositide 3-kinase-mTOR signalling and milk synthesis in mouse mammary epithelial cells.

We prove that centralisers of elements in [finitely generated free]-by-cyclic groups are computable. As a corollary, given two conjugate elements in a [finitely generated free]-by-cyclic group, the set of conjugators can be computed and the conjugacy problem with context-free constraints is decidable. We pose several problems arising naturally from this work.

There are instances when an aircraft encounters a bird’s flock or faces a heavy hailstorm, causing the windshield to sustain consecutive impacts. Therefore, the investigation of windshield resistance against repeated impacts is crucial. In this research, various tests such as tensile, split Hopkinson pressure bar (SHPB), and three-point bending are conducted to extract the mechanical properties of the materials used in a five-layers windshield under high strain rates. Using this information, the bird impact on the windshield is simulated using the smooth particle hydrodynamics (SPH) method, and the results are compared with real bird impact test outcomes, and the validation of this simulation is confirmed. The simulation of two consecutive bird strikes indicates the current windshield lacks sufficient resistance against successive dual impacts; in such scenarios, the second bird penetrates the windshield after breaking it and tearing the interlayer. Considering new materials and thicknesses for each windshield layer, a Taguchi experimental design method is employed to examine various layer arrangements with different materials and thicknesses. The configurations in which the windshield can withstand a maximum of three bird impacts in succession are identified. Subsequently, using the “the smaller, the better” criterion in the Taguchi optimisation approach, the configuration that not only prevents bird penetration but also minimises the maximum strain in the inner layer is selected as the desired outcome. Thus, a new five-layer windshield with new materials and thicknesses is presented, which is resistant to the repeated collision of up to three birds, tearing in the interlayer and bird penetration does not happen.

X-ray diffraction (XRD) characterization of Si powder was carried out using synchrotron and laboratory sources. Microstructural (size-strain) analyses of XRD patterns were carried out using the Rietveld refinement method. Experimentally observed super-Lorentzian shapes of the XRD peaks of Si powder were examined using multimodal profile fitting and bimodal model was found to be adequate. The two components obtained using a bimodal approach are referred as narrow and broad profiles based on their estimated relative peak widths. Peak shapes of crystallite size-dependent parts of narrow and broad profiles were found to be almost Gaussian and Lorentzian in nature, respectively. The simultaneous presence of such peak shapes corresponding to a bimodal microstructure is uncommon in literature. Therefore, in order to explore the role of different natures of XRD peak shapes (size dependent) of the bimodal profiles of Si, detailed microstructural analysis was carried out using the complementary method of whole powder pattern modeling (WPPM) and found to be related to the variance of crystallites' size distribution. Additionally, the effect of instrument resolution (laboratory and synchrotron sources) on the microstructural parameters was also studied. Scanning and transmission electron microscopy were used to characterize the morphology of Si powder and correlate with the microstructural findings of XRD methods.

This study analyzes Jane Addams’ contribution to an enduring topic: how marginalized people join the public from beyond political, socioeconomic, cultural, and gendered barriers. I study Addams’ book, The Long Road of Woman's Memory (1916), which discusses the seemingly irrational devil baby case in Chicago. Using the concept of public and hidden transcripts and the method of cultural discourse analysis, I contextualize the book within the theorizing around the concept of the public by Addams’ contemporaries, Gabriel Tarde and Robert E. Park. The analysis shows that Addams’ discussion aligns with three conceptual aspects of the formation of the public. First, Addams describes the awakening of consciousness about a collectively relevant concern, and second, the emergence of interaction about the topic. Third, Addams constructs a conceptual distinction between two functions of memory, highlighting independent critical judgment as the divider between the two, which is the decisive factor that Park argues distinguishes the public from the crowd. Addams’ writing contains an unusual perspective in that she discusses development toward the formation of something like the public in a marginalized communicative culture. Instead of focusing on performative and dramatic public debate, Addams addresses discreet genres of communication and illustrates their public relevance.

We show cash windfalls affect the real economy by spurring entrepreneurship. We identify these effects using the Spanish Christmas Lottery, which provides a unique setting as prizes are geographically concentrated and distributed among thousands of households. We find higher start-up entry, job creation, and self-employment in winning regions. Consistent with a financial constraints channel, results are strongest in sectors relying on external finance and regions with limited credit access. Newly created firms are larger, more profitable, and survive longer. For existing firms, however, growth and profitability do not respond to lottery awards, but wages increase due to tighter labor markets.

Children hospitalised with severe malnutrition have high mortality and readmission rates post-discharge. Current milk-based formulations target restoring ponderal growth but not the modification of gut barrier integrity or microbiome which increases the risk of gram-negative sepsis and poor outcomes. We propose that legume-based feeds rich in fermentable carbohydrates will promote better gut health and improve overall outcomes. We conducted an open-label phase II trial at Mbale and Soroti Regional Referral Hospitals, Uganda, involving 160 children aged 6 months to 5 years with severe malnutrition (mid-upper arm circumference (MUAC) < 11·5 cm and/or nutritional oedema). Children were randomised to a lactose-free, chickpea-enriched legume paste feed (LF) (n 80) v. WHO standard F75/F100 feeds (n 80). Co-primary outcomes were change in MUAC and mortality to day 90. Secondary outcomes included weight gain (> 5 g/kg/d), de novo development of diarrhoea, time to diarrhoea and oedema resolution. Day 90 MUAC increase was marginally lower in LF v. WHO arm (1·1 cm (interquartile range (IQR) 1·1) v. 1·4 cm (IQR 1·40), P = 0·09); day 90 mortality was similar (11/80 (13·8 %) v. 12/80 (15 %), respectively, OR 0·91 (95 % CI 0·40, 2·07), P = 0·83). There were no differences in any of the other secondary outcomes. Owing to initial poor palatability of the LF, ten children switched to WHO feeds. Per-protocol analysis indicated a trend to lower day 90 mortality and readmission rates in the LF (6/60 (10 %) and 2/60(3 %)) v. WHO feeds (12/71(17·5 %) and 4/71(6 %)). Further refinement of LF and clinical trials are warranted, given the poor outcomes in children with severe malnutrition.

We study pencils of curves on a germ of complex reduced surface $(S,0)$. These are families of curves parametrized by $ \mathbb{P}^1 $ having 0 as the unique common point. We prove that for $w\in \mathbb{P}^1$, the corresponding curve of the pencil does not have the generic topology if and only if either the corresponding curve of the pulled-back pencil to the normalized surface has a non generic topology or w is a limit value for the function $ f/g $ along the singular locus of $(S,0)$, where f and g are generators of the pencil.

Eye movement desensitisation and reprocessing (EMDR), a therapy initially developed by Dr Francine Shapiro for treating post-traumatic stress disorder, has broadened its scope to include other forms of stress and trauma, even showing promise for physical health conditions. This commentary on a series of three articles on EMDR in this journal outlines the therapy's underlying theoretical model, adaptive information processing (AIP), which involves trauma-focused case conceptualisation. It also introduces the work of the EMDR Council of Scholars, which identified three categories of treatment: EMDR psychotherapy, EMDR treatment protocols and EMDR-derived techniques. Finally, it considers EMDR training and credentialing and the aim of current leaders in the EMDR community to solidify EMDR's standing as a scientifically validated, front-line trauma therapy, while honouring Shapiro's legacy of striving to end the cycle of violence, especially in low- and middle-income countries.

Based on a contingent valuation method survey on air quality improvement in northern China, we construct several subjective perception determinants of respondents' valuation uncertainty from both the demand and perceived supply sides. Using the individual-level uncertainty measurements initially proposed by Wang and He (2011) and their alternative transformations, we analyze how these factors of demand and perceived supply sides affect people's valuation uncertainty. Our results demonstrate the significant contribution of these determinants in explaining respondents' uncertainty. On the demand side, people who ‘don't know much’ about benefits-related factors have the highest level of uncertainty, and those claiming to ‘know nothing’ most often report the lowest level of uncertainty. On the supply side, people who either do not trust or are not satisfied with the control policies tend to be more certain of their valuation. The subsequent analyses also suggest that these results be interpreted as negative certainty, which is attributed to a lack of interest.

Migratory birds are experiencing widespread population declines, underscoring the urgency of effective conservation actions. Long-term monitoring of migratory birds, especially during migration, is crucial for such actions yet remains technically challenging. Bioacoustic monitoring of nocturnal flight calls (NFCs) constitutes a promising technique to monitor migratory birds during migration. Such monitoring has increased in North America and Europe, but its application on the East Asian–Australasian Flyway (EAAF) remains limited. Here, we present findings from an NFC monitoring project conducted at a recording station in central Beijing, China over four migration seasons. From around 3,350 hours of recording effort, we manually extracted and identified 84,135 NFCs, involving at least 111 species or species groups that are associated with a wide range of habitat types. We also found that NFCs provided additional information on species’ migration phenology in comparison with citizen science observation data. To our knowledge, this study is the first formal investigation of bird migration using NFC monitoring on the EAAF, serving as a proof-of-concept case for wider, long-term monitoring efforts in this traditionally understudied region. Our findings also highlight the significance of incorporating migratory bird conservation into urban planning and land management practices.

Achieving optimal nutritional status in patients with penetrating Crohn’s disease is crucial in preparing for surgical resection. However, there is a dearth of literature comparing the efficacy of total parenteral nutrition (TPN) v. exclusive enteral nutrition (EEN) in optimising postoperative outcomes. Hence, we conducted a case-matched study to assess the impact of preoperative EEN v. TPN on the incidence of postoperative adverse outcomes, encompassing overall postoperative morbidity and stoma formation, among penetrating Crohn’s disease patients undergoing bowel surgery. From 1 December 2012 to 1 December 2021, a retrospective study was conducted at a tertiary centre to enrol consecutive patients with penetrating Crohn’s disease who underwent surgical resection. Propensity score matching was utilised to compare the incidence of postoperative adverse outcomes. Furthermore, univariate and multivariate logistic regression analyses were conducted to identify the risk factors associated with adverse outcomes. The study included 510 patients meeting the criteria. Among them, 101 patients in the TPN group showed significant improvements in laboratory indicators at the time of surgery compared with pre-optimisation levels. After matching, TPN increased the occurrence of postoperative adverse outcomes (92·2 % v. 64·1 %, P = 0·001) when compared with the EEN group. In the multivariate analysis, TPN showed a significantly higher OR for adverse outcomes than EEN (OR = 4·241; 95 % CI 1·567–11·478; P = 0·004). The study revealed that penetrating Crohn’s disease patients who were able to fulfil their nutritional requirements through EEN exhibited superior nutritional and surgical outcomes in comparison with those who received TPN.

The association of post-adoption experiences of discrimination with depressive symptoms was examined in 93 previously institutionalized (PI) youth (84% transracially adopted). Additionally, we explored whether sleep quality statistically moderated this association. Notably, we examined these associations after covarying a measure of autonomic balance (high/low frequency ratio in heart rate variability) affected by early institutional deprivation and a known risk factor for depression. PI youth exhibited more depressive symptoms and experiences of discrimination than 95 comparison youth (non-adopted, NA) raised in their biological families in the United States. In the final regression model, there was a significant interaction between sleep quality and discrimination, such that at higher levels of sleep quality, the association between discrimination and depression symptoms was non-significant. Despite being cross-sectional, the results suggest that the risk of depression in PI youth involves post-adoption experiences that appear unrelated to the impacts of early deprivation on neurobiological processes associated with depression risk. It may be crucial to examine methods of improving sleep quality and socializing PI youth to cope with discrimination as protection against discrimination and microaggressions.