Between 2006 and 2021, the Hungarian Twin Registry (HTR) operated a volunteer twin registry of all age groups (50% monozygotic [MZ], 50% dizygotic [DZ], 70% female, average age 34 ± 22 years), including 1044 twin pairs, 24 triplets and one quadruplet set. In 2021, the HTR transformed from a volunteer registry into a population-based one, and it was established in the Medical Imaging Centre of Semmelweis University in Budapest. Semmelweis University’s innovation fund supported the development of information technology, a phone bank and voicemail infrastructure, administrative materials, and a new website was established where twins and their relatives (parent, foster parent or caregiver) can register. The HTR’s biobank was also established: 157,751 individuals with a likely twin-sibling living in Hungary (77,042 twins, 1194 triplets, 20 quadruplets, and one quintuplet) were contacted between February and March of 2021 via sealed letters. Until November 20, 2022, 12,001 twin individuals and their parents or guardians (6724 adult twins, 3009 parents/guardians and 5277 minor twins) registered, mostly online. Based on simple self-reports, 37.6% of the registered adults were MZ twins and 56.8% were DZ; 1.12% were triplets and 4.5% were unidentified. Of the registered children, 22.3% were MZ, 72.7% were DZ, 1.93% were triplets, and 3.05% were unidentified. Of the registered twins, 59.9% were female (including both the adult and minor twins). The registration questionnaire consists of eight parts, including socio-demographic and anthropometric data, smoking habits and medical questions (diseases, operations, therapies). Hungary’s twin registry has become the sole and largest population-based twin registry in Central Eastern Europe. This new resource will facilitate performing world-class modern genetic research.

This article considers the role of experts and their interaction with the legal system to better understand the benefits and potential dangers of expert evidence to fact-finders in trials. Medical experts are indispensable to the administration of justice as litigation ranges beyond what judges or juries comfortably deal with as facts of everyday life. This would render courts, absent expert evidence, vastly under-equipped in making decisions of fact. However, the dangers of surrendering authority to experts or of misunderstanding their role must be considered to ensure that expert evidence is used to benefit the administration of justice.

We consider the homology theory of étale groupoids introduced by Crainic and Moerdijk [A homology theory for étale groupoids. J. Reine Angew. Math. 521 (2000), 25–46], with particular interest to groupoids arising from topological dynamical systems. We prove a Künneth formula for products of groupoids and a Poincaré-duality type result for principal groupoids whose orbits are copies of an Euclidean space. We conclude with a few example computations for systems associated to nilpotent groups such as self-similar actions, and we generalize previous homological calculations by Burke and Putnam for systems which are analogues of solenoids arising from algebraic numbers. For the latter systems, we prove the HK conjecture, even when the resulting groupoid is not ample.

In this paper, we introduce a unique dataset derived from a survey conducted among 450 Syrian refugee workers and the owners/managers of the firms in which they are employed in Istanbul, Turkey. We utilise this data to investigate the connection between the wage-productivity gap and perceived economic and social discrimination. The findings of the study indicate that individuals facing a wider wage-productivity gap tend to report higher levels of economic and social discrimination. These results remain consistent even after incorporating various variables at both the worker and firm levels into the analysis. These findings imply potential policy recommendations that policymakers should take into account.

Americans generally celebrate the abstract principle of diversity, but research suggests that they have a comparatively lower (1) favorability towards policies that promote diversity and (2) sense of personal closeness with others from diverse backgrounds. The current study analyzes nationally representative survey data to assess such “principle-policy gaps” and “principle-personal gaps” in Americans’ diversity attitudes. We find that these attitudinal gaps indeed exist and are substantial in the general population. We also consider how individual-level factors relate to these attitudinal gaps. Following common findings in previous research, we find that participant racial identity and political partisanship have statistically significant relationships with these attitudinal gaps. But our overall findings illustrate that principle-policy gaps and principle-personal gaps in diversity attitudes are fairly substantial and prevalent across Americans who vary by race, politics, and several other individual-level factors. We consider our findings in the current social and political context, and we discuss directions for future inquiry.

This article investigates legislators’ willingness to talk about gender and women during policy making discussions, asking whether it is conditional on their sex or partisanship in environments where party discipline does not constrain their speech. The Canadian Senate offers a case of a legislature with low or absent party discipline. A quantitative content analysis of nearly 1,000 Senate committee meetings confirms that sex is a primary indicator of legislators’ inclination to talk about gender and women. Moreover, women senators who sit on committees with a critical mass of women members (30% or greater) are more likely to talk about gender and women, making the case for the importance of women’s descriptive representation. Partisanship and independence had no significant effect on senators’ propensity to discuss women. The findings suggest that partisanship does not constrain legislators’ representation of women in environments with low party discipline.

The NIST Workshop: Integrating Crystallographic and Computational Approaches to Carbon-Capture Materials for the Mitigation of Climate Change took place from October 31–November 1, 2023 at the National Cybersecurity Center of Excellence (NCCoE) Compound in Rockville, MD, which is an off-campus NIST facility. This workshop provided a forum for experimentalists and theorists working on the structural aspects of CO2 capture and sequestration materials to review the current state of the art in this field and discuss opportunities for collaborative research required to develop tools for rapid determination of the structure and its effect on the direct air capture performance in porous solid sorbents. We had a total of 33 international participants (18 invited speakers) from 17 institutions who were experimentalists and theorists from academia, government, and industry. The workshop was a great success.

Infections cause substantial morbidity and mortality among patients receiving care in outpatient hemodialysis facilities. We describe comprehensive infection prevention assessments by US public health departments using standardized interview and observation tools. Results demonstrated how facility layouts can undermine infection prevention and that clinical practices often fall short of policies.

Let ${\mathcal G}$ be a linear algebraic group over k, where k is an algebraically closed field, a pseudo-finite field or the valuation ring of a non-archimedean local field. Let $G= {\mathcal G}(k)$. We prove that if $\gamma\in G$ such that γ is a commutator and $\delta\in G$ such that $\langle \delta\rangle= \langle \gamma\rangle$ then δ is a commutator. This generalises a result of Honda for finite groups. Our proof uses the Lefschetz principle from first-order model theory.

Infection mechanism plays a significant role in epidemic models. To investigate the influence of saturation effect, a nonlocal (convolution) dispersal susceptible-infected-susceptible epidemic model with saturated incidence is considered. We first study the impact of dispersal rates and total population size on the basic reproduction number. Yang, Li and Ruan (J. Differ. Equ. 267 (2019) 2011–2051) obtained the limit of basic reproduction number as the dispersal rate tends to zero or infinity under the condition that a corresponding weighted eigenvalue problem has a unique positive principal eigenvalue. We remove this additional condition by a different method, which enables us to reduce the problem on the limiting profile of the basic reproduction number into that of the spectral bound of the corresponding operator. Then we establish the existence and uniqueness of endemic steady states by a equivalent equation and finally investigate the asymptotic profiles of the endemic steady states for small and large diffusion rates to provide reference for disease prevention and control, in which the lack of regularity of the endemic steady state and Harnack inequality makes the limit function of the sequence of the endemic steady state hard to get. Finally, we find whether lowing the movements of susceptible individuals can eradicate the disease or not depends on not only the sign of the difference between the transmission rate and the recovery rate but also the total population size, which is different from that of the model with standard or bilinear incidence.

The concept of degrowth aligns with the principles of Climate and Environmental Justice (CEJ) in significant aspects. Both frameworks underline the need for new global structures and social movements that promote ecological conservation, local economic regeneration, and social well-being that goes beyond material accumulation. Therefore, degrowth can reinforce the pursuit of transformative global climate justice. However, I contend that significant contradictions remain between degrowth and North–South climate justice. I argue that on both conceptual and policy grounds, a ‘strong version’ of the green economy provides a better foundation for seeking international climate justice for Africa than degrowth. I also contend that green growth is a more pragmatic and realistic approach to global climate justice because it is more sensitive to the norms, structures, and dynamics of global politics.

Oral health is a critical component of overall health and well-being, not just the absence of disease. The objective of this review paper is to describe relationships among diet, nutrition and oral and systemic diseases that contribute to multimorbidity. Diet- and nutrient-related risk factors for oral diseases include high intakes of free sugars, low intakes of fruits and vegetables and nutrient-poor diets which are similar to diet- and nutrient-related risk factors for systemic diseases. Oral diseases are chronic diseases. Once the disease process is initiated, it persists throughout the lifespan. Pain and tissue loss from oral disease leads to oral dysfunction which contributes to impaired biting, chewing, oral motility and swallowing. Oral dysfunction makes it difficult to eat nutrient-dense whole grains, fruits and vegetables associated with a healthy diet. Early childhood caries (ECC) associated with frequent intake of free sugars is one of the first manifestations of oral disease. The presence of ECC is our ‘canary in the coal mine’ for diet-related chronic diseases. The dietary sugars causing ECC are not complementary to an Eatwell Guide compliant diet, but rather consistent with a diet high in energy-dense, nutrient-poor foods – typically ultra-processed in nature. This diet generally deteriorates throughout childhood, adolescence and adulthood increasing the risk of diet-related chronic diseases. Recognition of ECC is an opportunity to intervene and disrupt the pathway to multimorbidities. Disruption of this pathway will reduce the risk of multimorbidities and enable individuals to fully engage in society throughout the lifespan.

We combine unsupervised machine learning and econometric methods to study England’s print culture in the pivotal sixteenth and seventeenth centuries. Machine learning synthesizes the content of 57,863 texts comprising 83 million words into 110 topics. Topics include the expected, such as Natural Philosophy, and the unexpected, such as Baconian Theology. Timelines suggest that religious and political discourse gradually became less antagonistic and economic topics more prominent. The epistemology associated with Bacon was present in theological debates already before Bacon’s epistemological contributions. Vector autoregression estimates provide insight into the coevolution of ideas on religion, science, and institutions. Innovations in religious ideas stimulated focus on science, especially at times when Puritanism was prominent in religious discourse. Neither science nor institutional thought evidence secularization. The Glorious Revolution and the Civil War did not spur debates on institutions nor did the founding of the Royal Society markedly elevate attention to science.

In this paper, we show how to represent a non-Archimedean preference over a set of random quantities by a nonstandard utility function. Non-Archimedean preferences arise when some random quantities have no fair price. Two common situations give rise to non-Archimedean preferences: random quantities whose values must be greater than every real number, and strict preferences between random quantities that are deemed closer in value than every positive real number. We also show how to extend a non-Archimedean preference to a larger set of random quantities. The random quantities that we consider include real-valued random variables, horse lotteries, and acts in the theory of Savage. In addition, we weaken the state-independent utility assumptions made by the existing theories and give conditions under which the utility that represents preference is the expected value of a state-dependent utility with respect to a probability over states.

Post-cessation nationhood in South Sudan presented a paradoxical situation: a country united during struggle is fragmented after independence. Among the triggers for this scenario was the death of Dr John Garang de Mabior—the country’s founding father. This article is a multidisciplinary semiotic critique of Akuol de Mabior’s film, No Simple Way Home (2023), against the history of South Sudanese nationhood. Without claiming a political scientific analysis, the author proposes that South Sudan’s crisis of nationhood is symptomatic of a quest for a unifying icon. He theorizes the protagonist’s quintessence of motherhood as a semiotic gesture of her de jure iconicity of unified nationhood.