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A $(k+r)$-uniform hypergraph $H$ on $(k+m)$ vertices is an $(r,m,k)$-daisy if there exists a partition of the vertices $V(H)=K\cup M$ with $|K|=k$, $|M|=m$ such that the set of edges of $H$ is all the $(k+r)$-tuples $K\cup P$, where $P$ is an $r$-tuple of $M$. We obtain an $(r-2)$-iterated exponential lower bound to the Ramsey number of an $(r,m,k)$-daisy for $2$-colours. This matches the order of magnitude of the best lower bounds for the Ramsey number of a complete $r$-graph.
The calcium-sensing receptor (CaSR) is a critical mediator of calcium homeostasis in various tissues. Its role in human reproduction, especially in sperm function and male fertility, remains not fully elucidated. This study investigates the expression patterns of CaSR in normal and abnormal sperm and spermatogenic cells and evaluates its potential effect on sperm motility and morphology. Using immunohistochemistry (IHC), quantitative PCR (qPCR), we assessed the expression levels of CaSR in normal sperm, spermatogonia, and cases of asthenozoospermia, oligozoospermia, and teratozoospermia. In vitro functional assays were performed to analyze the effects of CaSR modulation on sperm motility under varying conditions, including the presence of specific CaSR agonists and antagonists. Our study revealed distinct patterns of CaSR expression in normal sperm and spermatogonia compared with those in abnormal sperm samples, particularly in cases of asthenozoospermia, oligozoospermia, and teratozoospermia. A marked decrease in CaSR expression was evident in these abnormal samples, highlighting its significance in normal sperm functionality. Functional assays further elucidated the role of CaSR in sperm motility. Activation of CaSR through specific agonists enhanced sperm motility, while inhibition by antagonists led to reduced motility. Our findings suggest that CaSR plays a significant role in maintaining sperm functionality and that changes in its expression may be associated with male infertility. These insights into the molecular underpinnings of sperm physiology highlight CaSR as a potential therapeutic target for treating certain forms of male infertility.
We are interested in the two-dimensional four-constant Riemann problem to the isentropic compressible Euler equations. In terms of the self-similar variables, the governing system is of nonlinear mixed-type and the solution configuration typically contains transonic and small-scale structures. We construct a supersonic-sonic patch along a pseudo-streamline from the supersonic part to a sonic point. This kind of patch appears frequently in the two-dimensional Riemann problem and is a building block for constructing a global solution. To overcome the difficulty caused by the sonic degeneracy, we apply the characteristic decomposition technique to handle the problem in a partial hodograph plane. We establish a regular supersonic solution for the original problem by showing the global one-to-one property of the partial hodograph transformation. The uniform regularity of the solution and the regularity of an associated sonic curve are also discussed.
The appropriate response to mass causality biological events requires well-established preparedness and providing a surge capacity. In such a situation, a practical solution is to convert large public venues into shelter hospitals. Due to the lack of a guideline for the transformation of a large public center into a hospital, the present study collected the design criteria for the transformation of public buildings into shelter hospitals in response to biological events such as epidemics or mass causality biological accidents.
Methods
The keywords were searched in Scopus, Web of Science, and PubMed databases until November 2021. This systematic review was conducted using terms related to mass causality biological accidents, shelter hospitals, and design criteria.
Results
Of 1802 extracted articles, duplicates (n = 280) and unrelated publications (n = 1342) were left out in the initial evaluation. Among 180 remained papers, 29 records satisfied our criteria after reviewing abstracts and full texts. Most of the included studies were related to the transformation of public venues into hospitals in response to the coronavirus disease 2019 (COVID-19) pandemic. The investigated themes included site selection, layout and structure, waste and wastewater management, ventilation, communication, food and medicine delivery, humanitarians and social supports, post-treatment care, and Management measures.
Conclusions
In summary, large public venues are highly recommended alternatives for surge capacity in response to mass causality biological accidents. However, the main challenges for using these centers are the provision of basic requirements such as water and electricity, ventilation, and available space.
A major tenet of healthcare environmental cleaning focuses on high-touch surfaces (HTSs). HTSs have high rates of contamination, yet cleaning compliance remains low, particularly in patient-occupied rooms. This quality improvement study aimed to use human-centric and participatory design to modify an HTS cleaning checklist and conduct initial trial and evaluation.
The dynamics of a single highly elastic fibre settling under gravity in a very viscous fluid is studied numerically. We employ the bead model and multipole expansion of the Stokes equations, corrected for lubrication that is implemented in the precise Hydromultipole numerical codes. Four attracting regular dynamical modes of highly elastic fibres are found: two stationary shapes (one translating and the other rotating and translating), and two periodic oscillations around such shapes. The phase diagram of these modes is presented. It illustrates that the existence of each mode depends not only on the elasto-gravitation number but also on the fibre aspect ratio. Characteristic time scales, fibre deformation patterns and motion in the different modes are determined.
Performing tasks in agriculture, such as fruit monitoring or harvesting, requires perceiving the objects’ spatial position. RGB-D cameras are limited under open-field environments due to lightning interferences. So, in this study, we state to answer the research question: “How can we use and control monocular sensors to perceive objects’ position in the 3D task space?” Towards this aim, we approached histogram filters (Bayesian discrete filters) to estimate the position of tomatoes in the tomato plant through the algorithm MonoVisual3DFilter. Two kernel filters were studied: the square kernel and the Gaussian kernel. The implemented algorithm was essayed in simulation, with and without Gaussian noise and random noise, and in a testbed at laboratory conditions. The algorithm reported a mean absolute error lower than 10 mm in simulation and 20 mm in the testbed at laboratory conditions with an assessing distance of about 0.5 m. So, the results are viable for real environments and should be improved at closer distances.
We investigate the list packing number of a graph, the least $k$ such that there are always $k$ disjoint proper list-colourings whenever we have lists all of size $k$ associated to the vertices. We are curious how the behaviour of the list packing number contrasts with that of the list chromatic number, particularly in the context of bounded degree graphs. The main question we pursue is whether every graph with maximum degree $\Delta$ has list packing number at most $\Delta +1$. Our results highlight the subtleties of list packing and the barriers to, for example, pursuing a Brooks’-type theorem for the list packing number.
Alpine tundra areas are threatened by anthropogenic climate change. They are also often represented as hotspots of endemism. Studying the insect communities associated with these habitats is therefore highly relevant. Melanoplus gaspesiensis Vickery is a grasshopper species known for its extremely limited distribution; it is considered endemic to Mont Albert, on the Gaspé Peninsula, Québec, Canada. Given its extremely limited distribution and with its habitat being particularly sensitive to climate change, the species is likely to soon be considered “at risk” at both the provincial and national levels. In order to confirm the current distribution of M. gaspesiensis, we sampled Acrididae on four alpine summits of the Gaspé Peninsula. Four species of Acrididae were captured. Almost 85% of the captured specimens were M. gaspesiensis, all of which were captured on Mont Albert. Our data are thus coherent with the species being endemic to that summit. The unique geology of Mont Albert (serpentine) may explain why M. gaspesiensis appears to be restricted to this one summit.
During the Nigerian Civil War, France became the main supplier of military assistance to the secessionist Biafra. In a neo-imperial pursuit to weaken the potential regional hegemon Nigeria, it secretly provided arms and ammunition to the Biafrans in collusion with Côte d'Ivoire and Gabon. Yet the driving force behind this Franco-African arms triangle was not the Elysée, but the Ivorian president Félix Houphouët-Boigny. Newly unearthed documentary evidence from French archives enables this article to break new historiographical ground: firstly, to show the Elysée's sheer reluctance to militarily assist Biafra and lack of a coherent policy in doing so; secondly, to confirm Houphouët-Boigny as the “mastermind” behind the arming of Biafra, as well as to identify his Cold War motivations; thirdly, to uncover Gabonese president Omar Bongo's increasing agency and influence in the scheme; fourthly, to demonstrate that it was the Ivorian and Gabonese presidents who transformed the arms triangle into a square by bringing the Rhodesians and, especially, the South Africans in; and, finally, to retrace the emergence and functioning of the “African-French” military assistance to Biafra at the policy level not only from Paris's, but also Abidjan's and Libreville's perspectives.
This response to the comments on The Digital Factory discusses why and how the concepts of the digital factory and digital Taylorism have been applied in the book, as well as the question of the relationship between digital control and workers' resistance to algorithmic management technologies. While agreeing with the comments that point to the limitations of the concepts used, this response argues that these can be productive precisely by drawing our attention to aspects that are otherwise difficult to bring to light. In terms of the potential for workers' resistance, many collective and individual forms of such resistance remain possible in labour regimes under algorithmic management, as well as in other coexisting labour regimes.
Theories about the impact of digital technology on society and the development of capitalism and debates about the influence of digital information technologies on the future of work have been abundant since the end of the twentieth century. Most of the academic debate has taken place outside labour history, leaving the actual effects of digital technologies on human work and labour relations often overlooked. Moritz Altenried's The Digital Factory: The Human Labor of Automation focuses precisely on these effects, and as such provides a good opportunity to engage with these debates from a labour history perspective. This Review Dossier includes four comments on Altenried's book, by Bridget Kenny, Nico Pizzolato, Görkem Akgöz, and Greg Downey, to which the author responds. The contributors focus on different aspects of The Digital Factory depending on their own perspective on recent developments in the digital economy in the larger context of global capitalism.
This article describes John Wesley's evolving visions of Christian singleness (celibacy) and three commitments related to his changing views: a commitment to celibacy in an Oxford college; a commitment to marriage with Mary Vazeille; a de facto commitment to single life after Mary's separation from him. Protestant Churches lacked structures to support celibate commitment, structures that might have discouraged his unguarded and intimate correspondence with married women that lay behind his separation from Mary. The article asks why Protestants, although formally allowing single life, have not found ways to honour commitments to it.
Coronavirus disease 2019 (COVID-19) has caused psychological distress among health-care professionals (HCP) worldwide, suggesting that morale could also be affected. This warrants further investigation as HCPs’ morale directly impacts delivery of quality care and work productivity. This study aims to explore the experiences of HCPs who served migrant workers in a local COVID-19 hotspot in Singapore and the impact on their morale.
Methods
Eleven volunteer HCPs from a regional hospital in Singapore who served migrant workers in a local COVID-19 hotspot were recruited. Semi-structured face-to-face interviews were conducted, and recordings were transcribed verbatim. Transcripts were analyzed using thematic analysis. Morale of HCPs was evaluated based on responses.
Results
Four main themes emerged: motivators, challenges, support, and leadership. Motivators or factors that drove HCPs to serve include varying personal reasons and a sense of duty to do good. Challenges faced by HCPs include a language barrier, keeping up with rapidly changing workflows, fear of contagion, and coping with emotions. Support and leadership were revealed to have boosted HCPs’ morale.
Conclusions
Peer and social support and effective leadership have potential protective effects on HCPs’ morale against negative experiences faced during the COVID-19 pandemic.