Batteries containing cobalt will play a central role in the global transition to cleaner energy. Most of the world’s cobalt comes from the Democratic Republic of the Congo (DRC). However, the negative human rights image of the minerals sector in the DRC, and the emergence of an inaccurate and exploitative “blood cobalt” narrative risks harming small-scale, ‘artisanal’ producers who rely on this industry for their livelihood. The DRC government, civil society and small-scale producers already have a roadmap for ending child labour and improving working conditions. Countries and companies whose economies and business interests rely on these precious natural resources should engage with this roadmap rather than disengaging from the country’s mining sector altogether.

This paper proposes a nonparametric test to assess whether there exist heterogeneous quantile treatment effects (QTEs) of an intervention on the outcome of interest across different sub-populations defined by covariates of interest. Specifically, a consistent test statistic based on the Cramér–von Mises type criterion is developed to test if the treatment has a constant quantile effect for all sub-populations defined by covariates of interest. Under some regularity conditions, the asymptotic behaviors of the proposed test statistic are investigated under both the null and alternative hypotheses. Furthermore, a nonparametric Bootstrap procedure is suggested to approximate the finite-sample null distribution of the proposed test; then, the asymptotic validity of the proposed Bootstrap test is theoretically justified. Through Monte Carlo simulations, we demonstrate the power properties of the test in finite samples. Finally, the proposed testing approach is applied to investigate whether there exists heterogeneity for the QTE of maternal smoking during pregnancy on infant birth weight across different age groups of mothers.

This article examines a new dataset of radiocarbon dates that provides insights into the progressive installation of Inca infrastructure in the Copiapo Valley, situated at the southern edge of the Atacama Desert in northern Chile. It shows that the Inca imperial expansion in this region was not a linear process and was likely shaped by local negotiations and conflicts. The findings describe three main stages of Inca expansion. The first is the construction of the North–South Inca Road and the establishment of high-altitude mountain shrines. The next stage consisted of a physical intervention in a local village located in the upper valley, including the construction of administrative buildings and public spaces. The last stage involved indirect intervention in local villages, characterized by the presence of isolated administrative buildings that were potentially used for diplomacy and negotiation. I argue that the Inca imperial expansion, characterized by evolving strategies across regions and time periods, not only demonstrates the state's capacity for learning but also suggests the pivotal role of local actors in positions of power who wielded agency to shape these developments.

We revise the conventional wisdom that Africa’s international borders were drawn arbitrarily. Europeans knew very little about most of Africa in the mid-1880s, but their self-interested goals of amassing territory prompted intensive examination of on-the-ground conditions as they formed borders. Europeans negotiated with African rulers to secure treaties and to learn about historical state frontiers, which enabled Africans to influence the border-formation process. Major water bodies, which shaped precolonial civilizations and trade, also served as focal points. We find support for these new theoretical implications using two original datasets. Quantitatively, we analyze border-location correlates using grid cells and an original spatial dataset on precolonial states. Qualitatively, we compiled information from treaties and diplomatic histories to code causal process observations for every bilateral border. Historical political frontiers directly affected 62% of all bilateral borders. Water bodies, often major ones, comprised the primary border feature much more frequently than straight lines.

La organización social de las colonias españolas en América se caracterizó por la desigualdad, configurando estilos de vida disímiles dependiendo de la casta y estamento de pertenencia. Las investigaciones desarrolladas desde una perspectiva paleopatológica en la ciudad colonial de Mendoza (siglos dieciséis al diecinueve), ubicada en el centro-oeste del actual territorio argentino, permitió identificar estados de salud diferenciados en individuos inhumados en cementerios según su procedencia espacial (interior/exterior de los templos). El objetivo de este trabajo es evaluar la distribución de la enfermedad degenerativa articular (EDA) entre grupos de distinta procedencia socioeconómica, inhumados en cinco cementerios católicos coloniales del sitio Área Fundacional de Mendoza. Se relevaron superficies articulares apendiculares de 66 adultos de ambos sexos. No se registraron diferencias estadísticamente significativas entre individuos de diferentes sectores de inhumación, pero sí niveles de estrés mecánico-funcional diferenciados entre sexos según su procedencia social. Se discute la influencia del sexo, la edad y el tamaño corporal en las tendencias identificadas, siendo este último la variable que mayor influencia presentó. Los patrones de uso del cuerpo son interpretados en función del contexto histórico, el sexo y el estatus social del difunto y su familia.

In pornography, standard modeling contracts often require a performer to surrender rights over their public image and sexual media in perpetuity and across media. Under these contracts, performers are unable to determine who accesses, for what duration, and under what conditions, their sexual media. As a result, pornography has been described by some performers as a “life sentence”—a phrase which, if true, violates some strong intuitions we share about the importance of autonomy in sexual activity. Using the framework of “affirmative consent,” I argue that these contracts violate performers’ rights to sexual autonomy, and ought therefore to be considered objectionable. Overall, I argue that the legal regimes we create have a strong impact on people's lives, and more important than legislating individual outcomes, the type of infrastructure we build around people's decisions has the potential to radically empower—or disempower—those engaged in sex work.

The primary goal of the investigation was to analyse the anti-inflammatory and antioxidant properties of Gamma-linolenic acid (GLA) on rats with indomethacin (IND)-induced gastric ulcers. Thirty rats were divided into five groups: Control, IND (50 mg/kg, p.o.), IND pretreated with GLA 100 mg/kg (p.o. for 14 d), IND pretreated with GLA 150 mg/kg (p.o. for 14 d) and IND pretreated with omeprazole (20 mg/kg, p.o. for 14 d). The stomach tissues were examined to calculate the ulcer index and pH and analyse biochemical markers (prostaglandin E2 (PGE2), cyclooxygenase 1 (COX1), TNF-1, IL-6 and intercellular adhesion molecule-1 (ICAM1)) and oxidative stress parameters (malondialdehyde: (MDA), superoxide dismutase (SOD), glutathione (GSH) and CAT (catalase)) as well as undergo histopathological assessment. GLA 100 and 150 mg/kg showed a protective effect against IND-induced gastric damage. It reduced levels of COX1, TNF-1, IL-6 and ICAM and increased PGE2 levels. GLA also normalised antioxidant function by modulating MDA, SOD, GSH and CAT. GLA intervention protects against IND-induced gastric ulcers by restoring oxidant/antioxidant balance and reducing inflammation.

Michel Foucault once wrote, “Do not think that one has to be sad in order to be militant, even though the thing one is fighting is abominable. It is the connection of desire to reality (and not its retreat into the forms of representation) that possesses revolutionary force.”1 This affect of revolutionary force stems from the joyful militancy of bringing into existence the already possibly present worlds that are assumed to be impossible.2

Scholars have paid limited attention to the crucial relationship between Hegel's racism, his support for colonialism and his views on religion. This essay offers a critical reconstruction of how race and coloniality shape the question of religion (and vice versa) throughout Hegel's attempts to critique and ultimately vindicate European modernity. Paying special attention to the seminal role of ‘fetishism’ in his works, I argue that Hegel's intellectual concerns are racialized from the inception of his project. I conclude by suggesting an alternative philosophical approach to the concept of the ‘fetish’ and ‘fetishism’ to resist Hegel's racist and pro-colonial tendencies.

The problem of non-integrability of the circular restricted three-body problem is very classical and important in the theory of dynamical systems. It was partially solved by Poincaré in the nineteenth century: he showed that there exists no real-analytic first integral which depends analytically on the mass ratio of the second body to the total and is functionally independent of the Hamiltonian. When the mass of the second body becomes zero, the restricted three-body problem reduces to the two-body Kepler problem. We prove the non-integrability of the restricted three-body problem both in the planar and spatial cases for any non-zero mass of the second body. Our basic tool of the proofs is a technique developed here for determining whether perturbations of integrable systems which may be non-Hamiltonian are not meromorphically integrable near resonant periodic orbits such that the first integrals and commutative vector fields also depend meromorphically on the perturbation parameter. The technique is based on generalized versions due to Ayoul and Zung of the Morales–Ramis and Morales–Ramis–Simó theories. We emphasize that our results are not just applications of the theories.

With the progress of artificial intelligence, the digitalization of the lifeworld, and the reduction of the mind to neuronal processes, the human being appears more and more as a product of data and algorithms. Thus, we conceive ourselves “in the image of our machines,” and conversely, we elevate our machines and our brains to new subjects. At the same time, demands for an enhancement of human nature culminate in transhumanist visions of taking human evolution to a new stage. Against this self-reification of the human being, the present book defends a humanism of embodiment: our corporeality, vitality, and embodied freedom are the foundations of a self-determined existence, which uses the new technologies only as means instead of submitting to them. The book offers an array of interventions directed against a reductionist naturalism in various areas of science and society. As an alternative, it offers an embodied and enactive account of the human person: we are neither pure minds nor brains, but primarily embodied, living beings in relation with others. This general concept is applied to issues such as artificial intelligence (AI), transhumanism and enhancement, virtual reality, neuroscience, embodied freedom, psychiatry, and finally to the accelerating dynamics of current society which lead to an increasing disembodiment of our everyday life. The book thus applies cutting-edge concepts of embodiment and enactivism to current scientific, technological, and cultural tendencies that will crucially influence our society’s development in the twenty-first century.

This study examines the temporal and geographical evolution of polygenic scores (PGSs) across cognitive measures (Educational Attainment [EA], Intelligence Quotient [IQ]), Socioeconomic Status (SES), and psychiatric conditions (Autism Spectrum Disorder [ASD], schizophrenia [SCZ]) in various populations. Our findings indicate positive directional selection for EA, IQ, and SES traits over the past 12,000 years. Schizophrenia and autism, while similar, showed different temporal patterns, aligning with theories suggesting they are psychological opposites. We observed a decline in PGS for neuroticism and depression, likely due to their genetic correlations and pleiotropic effects on intelligence. Significant PGS shifts from the Upper Paleolithic to the Neolithic periods suggest lifestyle and cognitive demand changes, particularly during the Neolithic Revolution. The study supports a mild hypothesis of Gregory Clark’s model, showing a noticeable rise in genetic propensities for intelligence, academic achievement and professional status across Europe from the Middle Ages to the present. While latitude strongly influenced height, its impact on schizophrenia and autism was smaller and varied. Contrary to the cold winters theory, the study found no significant correlation between latitude and intelligence.