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Low level of resistance to major diseases such as ascochyta blight (AB), botrytis grey mould (BGM) and dry root rot (DRR) in the cultivated chickpea genepool necessitates harnessing wild Cicer species. Sixty-eight accessions belonging to eight annual wild Cicer species and seven chickpea cultivars were screened for AB, BGM and DRR under controlled environmental conditions over the years. Intra-accession variability was observed among wild Cicer accessions for each disease. Hence, progenies of single resistant plants were selected for further evaluations and the trait-specific genetic stocks (TGS) were developed for each disease after re-screening following the single seed descent method. For AB, a high level of resistance was identified in four accessions belonging to tertiary genepool species, ICC 17334 (Cicer judaicum), ICC 17302, ICC 17308 and ICC 20177 (C. bijugum). Nine accessions, ICC 17160, ICC 17264, ICC 17270, ICC 20170, ICC 20186, ICC 20225, ICC 20247, ICC 20251 and IG 72941 of primary (C. reticulatum) and one accession, ICC 20190 of secondary (C. echinospermum) genepool species were resistant to BGM whereas, four accessions, ICC 20187 (C. reticulatum) and ICC 20218, ICC 20244 and ICC 20257 (C. echinospermum) were resistant to DRR. Development and utilization of these TGS in chickpea pre-breeding will assist in developing disease-resistant chickpea cultivars with broad genetic base.
We conducted a population-based study using Ontario health administrative data to describe trends in healthcare utilization and mortality in adults with epilepsy during the first pandemic year (March 2020–March 2021) compared to historical data (2016–2019). We also investigated if changes in outpatient visits and diagnostic testing during the first pandemic year were associated with increased risk for hospitalizations, emergency department (ED) visits, or death.
Methods:
Projected monthly visit rates (per 100,000 people) for outpatient visits, electroencephalography, magnetic resonance, computed tomography, all-cause ED visits, hospitalizations, and mortality were calculated based on historical data by fitting monthly time series autoregressive integrated moving-average models. Two-way interactions were calculated using Quasi-Poisson models.
Results:
In adults with epilepsy during the first quarter of the pandemic, we demonstrated a reduction in all-cause outpatient visits, diagnostic testing, ED visits and hospitalizations, and a temporary increase in mortality (observed rates of 355.8 vs projected 308.8, 95% CI: 276.3–345.1). By the end of the year, outpatient visits increased (85,535.4 vs 76,620.6, 95% CI: 71,546.9–82,059.4), and most of the diagnostic test rates returned to the projected. The increase in the rate of all-cause mortality during the pandemic, compared to pre-pandemic, was greater during months with the lower frequency of diagnostic tests than months with higher frequency (interaction p-values <.0001).
Conclusion:
We described the impact of the pandemic on healthcare utilization and mortality in adults with epilepsy during the first year. We demonstrated that access to relevant diagnostic testing is likely important for this population while planning restrictions on non-urgent health services.
The Arcanum mission is a proposed L-class mother-daughter spacecraft configuration for the Neptunian system, the mass and volume of which have been maximised to highlight the wide-ranging science the next generation of launch vehicles will enable. The spacecraft is designed to address a long-neglected but high-value region of the outer Solar System, showing that current advances make such a mission more feasible than ever before. This paper adds to a series on Arcanum and specifically provides progress on the study of areas identified as critical weaknesses by the 2013–2022 decadal survey and areas relevant to the recently published Voyage 2050 recommendations to the European Space Agency (ESA).
Common lilac (Syringa vulgaris L.) is a popular landscaping plant. Our aim was to obtain a large set of single nucleotide polymorphism (SNP) markers, to reveal the precise identities of the investigated S. vulgaris accessions, and to discover genetic relationships among them. The studied plant material included local Finnish, previously unidentified accessions, known reference cultivars, and so-called historical accessions i.e., old shrubs growing in historic cultural landscapes. We intended to verify cultivar names for some valuable local common lilac accessions and to provide insights into the history of common lilac cultivation in Finland. In the analyses, we used a set of 15,007 SNP markers. First, polymorphic information contents were calculated (mean 0.190, range 0.012–0.500 per marker). Then, to investigate genetic relationships among genotypes, a phylogenetic tree was constructed, and a principal coordinate analysis was conducted. A Bayesian analysis of population structure was performed to determine the number and distribution of genetic clusters among samples. Genetic marker data combined with existing historical and phenotypic knowledge revealed novel information on the unidentified cultivars and on the genetic relationships among studied accessions and solved the arrival and early history of common lilac in Finland. Overall, such comprehensive genomic characterization and deep understanding of genetic relationships of S. vulgaris can be used when utilizing present cultivars and developing new ones in future breeding programs.
In 1520, during the midst of the conquest of Mexico, Spanish conquistadors and their Native allies embarked on a massive naval project—the construction of 13 brigantines and a canal—needed to help conquer the aquatic city of Tenochtitlan. In the dominant historical literature on the war, the Spanish tend to receive most, if not all, of the credit for the success of the nautical program. The contributions of their Native allies by contrast are little-known and oft-overlooked in the historiography. Drawing on Spanish and Indigenous sources, this article highlights the vital roles that Native peoples played in the naval episode, whether it be felling timbers, carving wood, transporting logs, or excavating the canal. In addition to labor services, it also considers the importance of Indigenous ecological and hydrological expertise, and demonstrates how such knowledge played a pivotal role in the overall success of the enterprise. I argue, ultimately, that these contributions made the Native peoples, and not the Spanish, the true masters of the amphibious operation. Along the way, this essay seeks to contribute to several important strands of scholarship, chiefly the New Conquest History, environmental histories of New Spain, and the burgeoning literature on Indigenous knowledge production in Spanish America.
Crop residue incorporation to the soil is an essential strategy to improve soil quality and crop productivity in order to attain sustainable development goals. Experiments were conducted to evaluate the differential effect of crop residues on CH4 production and consumption in a tropical vertisol. Soils were incubated with residues of cereals (maize and wheat) and legumes (chickpea and soybean) at 1% w/w, under non-flooded and flooded conditions to estimate CH4 consumption and CH4 production rates, respectively. Rates of CH4 production (ng CH4 produced g/soil/day) varied from 0.068 to 0.107 with lowest in chickpea residue and highest in wheat straw amended soil. CH4 consumption rates (ng CH4 consumed g/soil/day) was highest (0.79) in wheat straw amended soil and lowest (0.53) in chickpea residue amended soil. Organic carbon (%) and available NO3− (mM) contents increased significantly (P > 0.05) in residue amended soils over control under both flooded (methanogenic) and non-flooded (methane consuming) conditions. Abundance of methanogens and methanotrophs was estimated as mcr and pmoA gene copies g−1 soil, indicated that both the microbial groups were stimulated significantly due to the amendment of crop residues. Linear models exhibited significant correlation among CH4 production and consumption with organic carbon, available nitrate and microbial abundance. The study highlights that crop residues incorporation influences both CH4 consumption and production potential of soil and this effect is more pronounced with biomass of cereals than legumes.
In 2006, the authorities of the de facto state of Transnistria unilaterally held a sovereignty referendum. Almost all voters supported Transnistria gaining internationally recognized independence and subsequently integrating/associating with Russia. Despite such clear results, the poll was not recognized internationally and, consequently, not implemented. However, this was not a problem for the Transnistrian leadership, since the primary objective of the referendum was not to reallocate sovereignty, but to domestically empower Transnistria’s President Igor Smirnov. Based on the discourse of Transnistria’s next president, Yevgeniy Shevchuk, this article argues that the referendum was not placed in the dustbin of history. Analysis of the official Transnistrian news published during his presidency from 2011–2016 shows that Shevchuk re-exploited the 2006 sovereignty referendum. His aim was not to reallocate sovereignty either, but to reach the following goals: 1. procure legitimacy of the Transnistrian sovereignty cause internationally; 2. empower Transnistria vis-à-vis its parent state, Moldova; 3. boost relations with Transnistria’s patron, Russia; and 4. empower himself domestically. Arguably, the argument about the strategic use of past unilateral sovereignty referendums also works in cases of other de facto states, which can be analyzed using the analytical framework presented in this article.