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Developmental psychopathology started as an intersection of fields and is now a field itself. As we contemplate the future of this field, we consider the ways in which a newer, interdisciplinary field – human developmental neuroscience – can inform, and be informed by, developmental psychopathology. To do so, we outline principles of developmental psychopathology and how they are and/or can be implemented in developmental neuroscience. In turn, we highlight how the collaboration between these fields can lead to richer models and more impactful translation. In doing so, we describe the ways in which models from developmental psychopathology can enrich developmental neuroscience and future directions for developmental psychopathology.
A generalisation of the well-known Pell sequence $\{P_n\}_{n\ge 0}$ given by $P_0=0$, $P_1=1$ and $P_{n+2}=2P_{n+1}+P_n$ for all $n\ge 0$ is the k-generalised Pell sequence $\{P^{(k)}_n\}_{n\ge -(k-2)}$ whose first k terms are $0,\ldots ,0,1$ and each term afterwards is given by the linear recurrence $P^{(k)}_n=2P^{(k)}_{n-1}+P^{(k)}_{n-2}+\cdots +P^{(k)}_{n-k}$. For the Pell sequence, the formula $P^2_n+P^2_{n+1}=P_{2n+1}$ holds for all $n\ge 0$. In this paper, we prove that the Diophantine equation
Biofertilizers, such as arbuscular mycorrhiza fungi and phosphate-solubilizing bacteria (PSB), have been reported to enhance plant growth under water stress conditions. This study aimed to investigate the effect of different biofertilizers on potato photosynthesis and growth under water deficit stress. The experiment was conducted over two crop years (2019 and 2020) using a randomized complete block design with three replications. Four irrigation intervals (70, 90, 110 and 130 mm of cumulative evaporation) and six biofertilizer treatments (PSB, Funneliformis mosseae [FM], Rhizoglomus fasciculatum [RF], PSB + FM, PSB + RF and no use) were applied. Severe moisture stress (130 mm evaporation) compared to no stress (70 mm evaporation) increased substomatal carbon dioxide concentration. The application of biofertilizers improved tuber yield under severe moisture stress, with FM showing the highest increase (62.9%), followed by RF (59.8%) and PSB (48.4%). The use of PSB along with mycorrhizae led to a significant decrease in mycorrhizal colonization percentage at all irrigation levels. The highest percentage of colonization and net photosynthesis was obtained from the application of both mycorrhizal species under irrigation conditions after 70 mm of evaporation. The application of PSB alone resulted in a 14.6% increase in the transpiration rate, additionally, the use of mycorrhiza led to an 18.7% increase in stomatal conductivity compared to no-biofertilizer. The results suggest that the simultaneous use of PSB and mycorrhizae can be effective in mild moisture stress, but in severe moisture stress, the use of mycorrhizal species alone is more effective.
Many philosophical accounts of manipulation are blind to the extent to which actual people fall short of the rational ideal, while prominent accounts in political science are under-inclusive. We offer necessary and sufficient conditions – Suitable Reason and Testimonial Honesty – distinguishing manipulative from non-manipulative influence; develop a ‘hypothetical disclosure test’ to measure the degree of manipulation; and provide further criteria to assess and compare the morality of manipulation across cases. We discuss multiple examples drawn from politics and from public policy with particular attention to recent debates about the ethics and politics of nudge.
Certain entomopathogenic nematodes (EPNs) in the families Steinernematidae and Heterorhabditidae are among the most studied biocontrol tools, some of which are commercially available against pest insects. Their use against foliar and subterranean insect pests is largely unexplored in the Canadian Prairies. We conducted a laboratory-based study to produce baseline information on the biocontrol potential of a few commercial EPN species. Percent mortality of flea beetles, diamondback moths (DBMs), lygus, cabbage root maggots, and black cutworms (BCWs) was assessed after 72 hours exposure to Steinernema carpocapsae, S. kraussei, S. feltiae, and Heterorhabditis bacteriophora at varying concentrations (25, 50, 100, and 200 infective juveniles (IJs) per larvae, pupae, or cm2 of soil surface). Irrespective of concentration level, S. carpocapsae and S. kraussei caused significant mortality in DBM and BCW larvae compared with H. bacteriophora.S. kraussei, and S. feltiae were more efficient than S. carpocapsae in controlling root maggot larvae. H. bacteriophora caused zero mortality to root maggots at any concentration. Root maggot pupae were resistant to entry to EPN species tested, likely due to hard outer covering. Compared with root maggot pupae, a moderate level of mortality was observed in DBM pupae, suggesting differential ability of the tested EPNs in killing different life stages of certain pests. All nematode species tested caused low mortality (≤10%) in flea beetle adults. The findings of this investigation form fundamental data essential for carrying out field-based studies on canola and other related crops aimed at control and management of these pest species.
This study aims to investigate whether some of the Eurocentric and colonialist contents of Hegel's thought are open to criticism with elements of his own philosophy. First, I intend to show that some of these contents can be organized around the connection between ‘spirit’ and ‘progress’. I then construct an interpretation of Hegel's notion of spirit, based upon which I discuss its possibly pro-colonialist tendencies, arguing that disconnected from the philosophy of history it establishes a connection of autonomy and critique crucial even for anti-colonialist thought. Furthermore, following Adorno's criticism of Hegel, I investigate the possibility of finding in the ‘progress in the consciousness of freedom’ an experiential dimension capable of capturing its regressive moments. This analysis then leads to a discussion of colonization in the reconstruction of capitalist society presented in the Philosophy of Right, which reveals an important discrepancy, so I argue, concerning the Eurocentrism of the Philosophy of History. Finally, I propose a comparison of Hegel's discussion of colonization with Marx's theory of ‘primitive accumulation’, and evaluate thereby the pertinence of Hegel's connection between imperialism and the critique of capitalism.
We experienced the first case of a difficult-to-extract central venous catheter removed with a pacemaker lead removal system: a 14-year-old boy with Hirschsprung’s disease who had repeated catheter infections that could not be removed by traction. Because the catheter lumen was occluded, a suture was tied around the end of the catheter and the catheter was removed with a rotating dilator.
The Thue–Morse sequence $\{t(n)\}_{n\geqslant 0}$ is the indicator function of the parity of the number of ones in the binary expansion of nonnegative integers n, where $t(n)=1$ (resp. $=0$) if the binary expansion of n has an odd (resp. even) number of ones. In this paper, we generalize a recent result of E. Miyanohara by showing that, for a fixed Pisot or Salem number $\beta>\sqrt {\varphi }=1.272019\ldots $, the set of the numbers
is linearly independent over the field $\mathbb {Q}(\beta )$, where $\varphi :=(1+\sqrt {5})/2$ is the golden ratio. Our result yields that for any integer $k\geqslant 1$ and for any $a_1,a_2,\ldots ,a_k\in \mathbb {Q}(\beta )$, not all zero, the sequence {$a_1t(n)+a_2t(n^2)+\cdots +a_kt(n^k)\}_{n\geqslant 1}$ cannot be eventually periodic.
This paper investigates the question of how subjective probability should relate to binary belief. We propose new distance minimization methods, and develop epistemic decision-theoretic accounts. Both approaches can be shown to get “close” to the truth: the first one by getting “close” to a given probability, and the second by getting expectedly “close” to the truth. More specifically, we study distance minimization with a refined notion of Bregman divergence and expected utility maximization with strict proper scores. Our main results reveal that the two ways to get “close” to the truth can coincide.
Ductal stenting has transformed the care of neonates with ductal-dependent critical CHD, especially in low-income countries. In small infants, a 3.5- or 4-mm stent may lead to too much pulmonary blood flow resulting in pulmonary oedema. We herein presented a novel technique to restrict ductal stent flow in a premature neonate with pulmonary atresia and intact ventricular septum following radiofrequency perforation of the pulmonary valve.
Trans vaccenic acid (TVA, trans11–18 : 1) and cis9, trans11-CLA (also known as rumenic acid; RA) have received widespread attention as potentially beneficial trans-FA due to their putative health benefits, including anti-diabetic properties. The objective of this study was to determine the effects of beef fat naturally enriched with TVA and RA on parameters related to glucose homoeostasis and associated metabolic markers in diet-induced obese (DIO) mice. Thirty-six male C57BL/6J mice (8 weeks old) were fed for 19 weeks with either a control low-fat diet (CLF), a control high-fat diet (CHF), or a TVA+RA-enriched high-fat diet (EHF). Compared with CLF, feeding either CHF or EHF resulted in adverse metabolic outcomes associated with high-fat diets, including adiposity, impaired glucose control and hepatic steatosis. However, the EHF diet induced a significantly higher liver weight TAG content and elevated plasma alanine transaminase levels compared with the CHF diet. Collectively, the findings from this study suggest that EHF does not improve glucose tolerance and worsens liver steatosis in DIO mice. However, the adverse effects of EHF on the liver could be in part related to the presence of other trans-FA in the enriched beef fat.
A result of Gyárfás [12] exactly determines the size of a largest monochromatic component in an arbitrary $r$-colouring of the complete $k$-uniform hypergraph $K_n^k$ when $k\geq 2$ and $k\in \{r-1,r\}$. We prove a result which says that if one replaces $K_n^k$ in Gyárfás’ theorem by any ‘expansive’ $k$-uniform hypergraph on $n$ vertices (that is, a $k$-uniform hypergraph $G$ on $n$ vertices in which $e(V_1, \ldots, V_k)\gt 0$ for all disjoint sets $V_1, \ldots, V_k\subseteq V(G)$ with $|V_i|\gt \alpha$ for all $i\in [k]$), then one gets a largest monochromatic component of essentially the same size (within a small error term depending on $r$ and $\alpha$). As corollaries we recover a number of known results about large monochromatic components in random hypergraphs and random Steiner triple systems, often with drastically improved bounds on the error terms.
Gyárfás’ result is equivalent to the dual problem of determining the smallest possible maximum degree of an arbitrary $r$-partite $r$-uniform hypergraph $H$ with $n$ edges in which every set of $k$ edges has a common intersection. In this language, our result says that if one replaces the condition that every set of $k$ edges has a common intersection with the condition that for every collection of $k$ disjoint sets $E_1, \ldots, E_k\subseteq E(H)$ with $|E_i|\gt \alpha$, there exists $(e_1, \ldots, e_k)\in E_1\times \cdots \times E_k$ such that $e_1\cap \cdots \cap e_k\neq \emptyset$, then the smallest possible maximum degree of $H$ is essentially the same (within a small error term depending on $r$ and $\alpha$). We prove our results in this dual setting.
We simulate the head-on collision between vortex rings with circulation Reynolds numbers of 4000 using an adaptive, multiresolution solver based on the lattice Green's function. The simulation fidelity is established with integral metrics representing symmetries and discretization errors. Using the velocity gradient tensor and structural features of local streamlines, we characterize the evolution of the flow with a particular focus on its transition and turbulent decay. Transition is excited by the development of the elliptic instability, which grows during the mutual interaction of the rings as they expand radially at the collision plane. The development of antiparallel secondary vortex filaments along the circumference mediates the proliferation of small-scale turbulence. During turbulent decay, the partitioning of the velocity gradients approaches an equilibrium that is dominated by shearing and agrees well with previous results for forced isotropic turbulence. We also introduce new phase spaces for the velocity gradients that reflect the interplay between shearing and rigid rotation and highlight geometric features of local streamlines. In conjunction with our other analyses, these phase spaces suggest that, while the elliptic instability is the predominant mechanism driving the initial transition, its interplay with other mechanisms, e.g. the Crow instability, becomes more important during turbulent decay. Our analysis also suggests that the geometry-based phase space may be promising for identifying the effects of the elliptic instability and other mechanisms using the structure of local streamlines. Moving forward, characterizing the organization of these mechanisms within vortices and universal features of velocity gradients may aid in modelling turbulent flows.
We describe two kinds of regular invariant measures on the boundary path space $\partial E$ of a second countable topological graph E, which allows us to describe all extremal tracial weights on $C^{*}(E)$ which are not gauge-invariant. Using this description, we prove that all tracial weights on the C$^{*}$-algebra $C^{*}(E)$ of a second countable topological graph E are gauge-invariant when E is free. This in particular implies that all tracial weights on $C^{*}(E)$ are gauge-invariant when $C^{*}(E)$ is simple and separable.