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There’s a tension at the heart of Justice for Animals.1 Some humans, says Nussbaum, can realize important capabilities only through consuming certain animal products—through not adopting a vegan diet. Consequently, the entitlements of some humans conflict with the entitlements that the capabilities approach grants to the animals these humans (would) eat. After all, animal agriculture almost invariably involves killing animals, violating animals’ bodily integrity, controlling animals’ life prospects and affiliations, and limiting animals’ ability to sense, reason, and play. Is this tragic conflict resolvable? Or must we accept that one group—certain humans or certain animals—lose out?
We experimentally identify a rotational motion of a single microalga (Chlamydomonas reinhardtii) within a microcontainer believed to be induced by one defective flagellum. We numerically adapt the classic two-dimensional squirmer model to replicate this unique motion by partially inhibiting the slip velocity on the boundaries of the squirmer. Subsequently, we employ a lattice Boltzmann method to simulate the motion of the single microalga with one defective flagellum. We examine the influence of swimming Reynolds numbers, self-propelling strength ($\beta$) and angle ($\alpha$) on the locomotion of the squirmer with one defective flagellum. The results indicate that a large $\beta$ leads to a large rotational diameter, positively correlating with the speed. Additionally, we observe that a low self-propelling strength ($\beta =0.5$) yields a monotonically increasing speed for the squirmer with $\alpha$. In general, high $\beta$ values result in fast speeds for the squirmer. This differs from the behaviour observed in a classic squirmer ($\alpha =360^{\circ }$), where high $\beta$ leads to a slow speed of puller ($\beta \gt 0$) owing to weak fluid inertia effects. Meanwhile, the energy expenditure increases monotonically with $\alpha$, contrasting with the non-monotonic trends observed for swimming speed and rotational diameter.
In the summer of 2023, approximately 2,000 young, dead penguins washed up on the beaches across Uruguay. The birds were thin, their stomachs empty, and scientists suggest that this mass death was due to starvation. Without fat, the penguins can’t keep warm in the colder waters that they now have to navigate to find food. Food shortages due to overfishing in South America may have contributed to their demise. This die-off was unprecedented for the species, although the magellanic penguin population has been consistently dropping, and the species is now considered near threatened. Impacts of climate change, which contributed to these penguins’ precarity, were also likely the cause of the mass deaths of penguins in New Zealand in 2022, when hundreds of little blue penguins washed up dead. They probably died because warming oceans forced them to venture into deeper and colder waters in search of food, causing them to dive to distances that are not sustainable. These birds were also found to be thinner than they should have been. An even more drastic penguin die-off occurred in Antarctica in 2022—over 10,000 emperor penguin chicks perished when the sea-ice they were growing up on melted before they had the fat and waterproofed feathers needed to survive in the cold waters. Most of the birds drowned or froze to death. These sorts of large-scale group deaths have led scientists to suggest that the emperor penguins will be extinct by the end of the century.
Calyptosuchus wellesi is an aetosaur known from the upper Blue Mesa Member and lowermost Sonsela Member of the Chinle Formation in Arizona, and the Tecovas Formation of the Dockum Group of Texas. The taxon is considered biostratigraphically informative and aids in correlating Upper Triassic strata across the southwestern United States. Our anatomical understanding of Calyptosuchus was primarily based on the holotype specimen from Texas and referred specimens, including several disarticulated elements from the Placerias Quarry in northern Arizona. We provide a re-interpretation of the holotype specimen and describe two new specimens referrable to Calyptosuchus from northern Arizona. Together these specimens provide new information on the cranial anatomy, including dentition, and the positional and intraspecific variation within the carapace and vertebral column of the taxon. This new evidence suggests that the skull anatomy of Calyptosuchus is more similar to that of Neoaetosauroides and Stagonolepis than to other aetosaurs. The dentition of Calyptosuchus supports recent hypotheses suggesting that aetosaurs were more omnivorous/faunivorous. The associated carapace expands our anatomical understanding of characters that vary among trunk paramedian osteoderms. We identify variation in the vertebral column within the trunk region, including the prominence of the centrodiapophyseal lamina and anatomy of the neural spine. Additionally, we report the first documentation of co-ossified sacral vertebrae within Calyptosuchus, which is also the first observation of this state within the Aetosauria outside of the Desmatosuchini. This suggests that co-ossification of the sacral vertebrae may be more prevalent within the Aetosauria than previously recognized.
Video-recordings are considered crucial for effective supervision, but empirical evidence is limited. We thus conducted a naturalistic study to assess supervisees’ evaluations of a structured video-supervision technique (‘Give Me 3’ [GM3]) compared with video-supervision as usual (VSAU) and supervision based on self-report (SAU). Twenty-four participants in postgraduate training in cognitive behavioural therapy conducted each supervision method and provided quantitative ratings of supervision satisfaction. A subsample of nine trainees participated in semi-structured qualitative interviews. Repeated-measure ANOVAs revealed no difference in post-session ratings of supervisees’ satisfaction with supervision. Retrospective comparisons of the three supervision methods resulted in significant differences in perceived effort and comfort but not in usefulness. The qualitative interviews suggested that the supervisees generally appreciated the benefits of video-supported supervision, while evaluations of GM3 and VSAU were mixed. VSAU and GM3 both appeared to have distinct advantages which might enrich supervision if aligned with the therapeutic context and supervisees’ goals.
Key learning aims
(1) How does trainees’ supervision satisfaction differ between supervision with or without the review of video-recorded therapy sessions?
(2) Is structured video-supervision perceived by trainee supervisees as being more satisfactory than unstructured video-supervision?
(3) How do supervisees perceive the differences between structured versus unstructured (video)supervision? When is each method deemed most useful?
We solve a Bayesian inverse Navier–Stokes (N–S) problem that assimilates velocimetry data by jointly reconstructing a flow field and learning its unknown N–S parameters. We devise an algorithm that learns the most likely parameters of a Carreau shear-thinning viscosity model, and estimates their uncertainties, from velocimetry data of a shear-thinning fluid. We conduct a magnetic resonance velocimetry experiment to obtain velocimetry data of an axisymmetric laminar jet in an idealised medical device (US Food and Drug Administration’s benchmark nozzle) for a blood analogue fluid. The algorithm successfully reconstructs the flow field and learns the most likely Carreau parameters. Predictions from the learned model agree well with rheometry measurements. The algorithm accepts any differentiable algebraic viscosity model, and can be extended to more complicated non-Newtonian fluids (e.g. Oldroyd-B fluid if a viscoelastic model is incorporated).
This article links two borderlands: the Italo-Slovene and the Slovene-Hungarian in the aftermath of the First World War. It focuses on the wartime refugees from the hinterlands of Trieste who, in accordance with agrarian reform, which the Yugoslav state began in 1919, were settled as colonists on the new Hungarian-South Slav border in the early 1920s. By using memoir literature and “ego documents,” the article tackles several aspects, including the refugee experience and social assistance during the First World War, the political motivation of the land reform, and the lived experiences of the colonists. In Yugoslavia, the agrarian problem was considered to be one of the most important issues facing the new state. The land reform aimed to solve social and national problems more than to improve the agricultural production of the state. In the example of the Prekmurje region, this article aims to show that interwar colonization succeeded in impacting the Hungarian–Slovene language border but failed miserably to ensure social transformation and security for the impoverished population.
We find that common ownership among acquirers enhances rather than hinders competition in the firm sale process. One common owner raises the likelihood that target firms are sold through auction (vs. negotiation with one buyer) by 21.5%. The effect is causal according to identifications based on mergers between financial institutions. Exploring economic channels, we observe selling firms respond to common ownership among acquirers by avoiding cross-owned acquirers, bargaining hard, and inviting more buyers when cross-owned acquirers initiate the deal but not by terminating the deal. Consistent with enhanced competition, common ownership among acquirers is positively associated with deal quality.
A linear stability analysis of a soluble surfactant-laden liquid film flowing down a compliant substrate is performed. Our purpose is to expand the prior studies (Carpenter and Garrad 1985 J. Fluid Mech.155, 465–510; Alexander et al., 2020 J. Fluid Mech.900, A40) by incorporating a soluble surfactant into the flow configuration. As a result, we formulate the Orr–Sommerfeld-type boundary value problem and solve it analytically by using the long-wave series expansion as well as numerically by using the Chebyshev spectral collocation method in an arbitrary wavenumber regime for infinitesimal disturbances. The long-wave result reveals that surface instability is stabilized in the presence of a surfactant, whereas it is destabilized in the presence of a compliant substrate. These opposing impacts suggest an analytical relationship between parameters associated with the soluble surfactant and compliant wall, ensuring the same critical Reynolds number for the emergence of surface instability corresponding to both surfactant-laden film flow over a compliant wall and surfactant-free film flow over a non-compliant wall. In the arbitrary wavenumber regime, along with the surface mode, we identify two additional modes based on their distinct phase speeds. Specifically, the wall mode emerges in the finite wavenumber regime, while the shear mode emerges only when the Reynolds number is large. As the surfactant Marangoni number increases, the wall mode destabilizes, resulting in a different outcome from the surface mode. Moreover, increasing the value of the ratio of adsorption and desorption rate constants stabilizes surface instability but destabilizes wall mode instability. As a result, we perceive that the soluble surfactant-laden film flow is linearly more unstable than the insoluble one due to surface instability but linearly more stable than the insoluble one due to wall mode instability. Additionally, we see a peculiar behaviour of base surface surfactant concentration on the primary instability. In fact, it has a specific value depending on adsorption and desorption rate constants below which surface instability stabilizes but wall mode instability destabilizes, whereas above which an opposite phenomenon occurs. Finally, in the high-Reynolds-number regime, we can suppress shear mode instability by raising the surfactant Marangoni number and the ratio of adsorption and desorption rate constants when the angle of inclination is sufficiently small. Unlike surface instability, the base surface surfactant concentration exhibits both stabilizing and destabilizing influences on shear mode instability.
To assess short- and medium-term outcomes of VenusP-valve implantation in the pulmonary position in the paediatric population.
Background:
Percutaneous pulmonary valve implantation is now an established alternative to surgical pulmonary valve replacement, especially in those with conduits in the right ventricular outflow tract. The VenusP-valve™ (Venus Medtech, Shanghai, China) has demonstrated early efficacy in the adult population with larger conduit-free right ventricular outflow tracts. However, its use in children has not been well described.
Methods:
Retrospective review of patients under 18 years of age undergoing VenusP-valve implantation at a single institution between June 2015 and February 2023.
Results:
Fifteen patients under the age of 18 years underwent VenusP-valve™ implantation. All had severe pulmonary regurgitation and fulfilled accepted criteria for pulmonary valve implantation. Mean age at valve implantation was 14.1 (range 9.8–17.9) years, and mean weight was 54.9 (34.0–98.5) kg. The valve was deployed successfully in all the patients. The valve diameter and length ranged between 28–36 mm and 25–35 mm, respectively. Mean follow-up was 3.4 (0.5–8.1) years. At follow-up, twelve patients have undergone magnetic resonance imaging MRI as part of the regular surveillance. Indexed right ventricular end-diastolic volume improved from 157.8 (140.0–197.0) ml/m2 to 117.6 (91.0–152.0) ml/m2 (p = 0.004). Pulmonary regurgitation fraction had reduced from a mean of 44.3 (31.0–60.0) % to 3.6 (0.0–15.0) % (p = 0.003).
Conclusion:
This study demonstrates the safety and feasibility of the VenusP-valve implantation in children. Medium-term follow-up suggests that valve implantation is associated with a reduction in the degree of pulmonary regurgitation and right ventricular end-diastolic volume.
Approximately one in three people who use anabolic-androgenic steroids (AASs) develop dependence, characterised by both psychiatric and somatic symptoms. Despite this, AAS use disorder (AASUD) is not distinctly recognised in the latest versions of either the ICD or DSM, impeding both clinical care and research progress. It is clear that AASUD shares many features and correlates with substance use disorders (SUDs) that have specific diagnostic criteria in these classification systems, such as stimulants or opioids. We aim to outline the overlap between AASUD and more ‘typical’ SUDs as well as highlight the specific concerns related to AASUD that warrant recognition and distinct diagnostic criteria.
Spontaneous flow reversals in buoyancy-driven flows are ubiquitous in many fields of science and engineering, often characterized by violent, intermittent occurrences. In this study, we present a complex-network-based reduced-order model to analyse intermittent events in turbulent flows, using temporal and spatial snapshot data. This framework combines elements of dynamical system theory with network science. We demonstrate its utility by applying it to data sequences from intermittent flow reversal events in two-dimensional thermal convection. This approach has proven robust in detecting and quantifying structures and predicting reversals. Additionally, it provides a perspective on the physical mechanisms underlying flow reversals through cluster evolution. This purely data-driven methodology shows the potential to enhance our understanding, prediction and control of turbulent flows and complex systems.
Globally, numerous infertile couples have been assisted by extensive research on mammalian fertilization and the rapid development of Assisted Reproductive Technology (ART). However, 5%–15% of the couples that are selected for in vitro fertilization (IVF) experience a total fertilization failure (TFF), where no zygotes develop despite oocytes and semen parameters appear to be normal. Notably, an essential early event in fertilization is the binding of spermatozoa to the oocyte’s external envelope, which followed by the spermatozoa-oocyte fusion. Meanwhile, oocyte activation is a crucial cellular process necessary to block polyspermy and start the development of the zygote. Improper membrane fusion of gametes has been demonstrated to be one of the mechanisms of TFF. Moreover, considering the large amount of research on sperm proteins in recent years, thus in this review, we characterize the role and molecular mechanisms of sperm proteins in the three key processes of gamete adhesion and fusion and oocyte activation, which would provide a comprehensive understanding of the role of sperm proteins in fertilization in mammals and a favourable reference for future studies in assisted reproduction due to FF.
This article seeks to challenge existing understandings of good work. It does so through a critical exploration of recognitive and craft conceptions of work, which are among the richest and most philosophically nuanced of extant accounts. The recognitive view emphasises work’s recognitive value through the social esteem derived from making a valuable social contribution. But by making recognition foundational, it is unable to appreciate the irreducible ethical significance of the objective quality of one’s work activity. The ‘craft ideal,’ by contrast, promises to provide a powerful basis for understanding the importance of rich, rewarding, and morally educative activities, but is undermined by a laudable but misdirected egalitarian impulse which prevents it from being able to properly distinguish good from bad work. One underlying aim of our discussion is to provoke deeper reflection from business ethicists regarding what we might want from an account of good work.
The focus of this paper is a first-century pseudepigraphic treatise titled On Human Nature, preserved by Stobaeus and attributed to the Pythagorean Aesara. Whether the treatise is to be ascribed to a woman philosopher named Aesara or the Pythagorean man Aresas is a point of controversy. In what follows, we gloss over the question of the identity and gender of the author and turn to the philosophical content of the treatise. In the surviving fragment, Aesara analyses the structure of the human soul and the relationships among its parts. The human soul becomes a model of law and justice for both the city and the household. Thus, On Human Nature revisits well-known Platonic doctrines, such as the city-soul analogy, the tripartition of the soul and the definition of justice as harmony, providing novel insights into their political implications. In what follows, we argue that Aesara constructs an original psychological theory by supplementing Plato’s tripartite conception of the soul in the Republic with aspects from later dialogues. Specifically, Aesara employs the Laws to stress the political implications of the tripartition and the leading role of νοῦς, and the Timaeus to explain our psychological reactions through physiological phenomena.