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Having hope is important for motivation and human agency, especially when it is certain. People with unwavering hope are more likely to succeed in their endeavours than those without. However, in modern debates, hope is usually seen as characterised by vain optimism. Thomas Aquinas, in contrast, argues that the virtue of hope is characterised by certainty – a view that could contribute significantly to these debates. Nevertheless, there seem to be problems with Aquinas’ view. He says that, while certainty essentially concerns the cognitive faculties, it can also concern other faculties byparticipation, insofar as the cognitive faculties influence them. He adds that hope can only be said to be certain by participating in the certainty proper to faith. But this reference to the certainty of faith and the cognitive faculties seems to imply that faith is endowed with conclusive evidence, since it is this evidence that enables the cognitive faculties to attain certainty. And throughout his writings, Aquinas denies that faith enjoys conclusive evidence. In this article, I will show that one can resolve this difficulty by understanding that for Thomas faith is indeed an intellectual act, but its certainty is different from the certainty of reason. This will enable us to gain an understanding of Aquinas’ view of the certainty of hope, as well as other aspects of his reflections on hope and faith.
The late Silurian to Early Devonian floras in the South China Block provide important evidence for the radiation of early land plants, including the well-known Posongchong Formation and Xujiachong Formation of Yunnan Province and the Pingyipu Group of Sichuan Province. However, some taxa in these stratigraphic units are described on the basis of limited specimens, or even a single and/or poorly preserved specimen, and need further investigation. The re-investigation of specimen PB6458 from the Xujiachong Formation at the Xujiachong section near Xujiachong Village, Qujing City, Yunnan Province, which is the holotype of Zosterophyllum spathulatum Li and Cai, 1977, reveals some new characters of its strobilus, sporophylls, and sporangia and denies its assignment to Zosterophyllum Penhallow, 1892. Instead, this specimen should be assigned to Adoketophyton subverticillatum (Li and Cai) Li and Edwards, 1992. This taxonomic revision extends the paleogeographic distribution of Adoketophyton Li and Edwards, 1992 and further enhances this genus as one of the index fossils of Lower Devonian non-marine strata in the South China Block.
This paper reports a study that investigated how first language (L1) reading comprehension, L1 low-level skills, working memory capacity, and reading anxiety are related to the accuracy of responses and completion time in a second language (L2) reading test. The data obtained from Hungarian secondary school learners of English showed that anxiety related to processing the L2 reading text, time pressure, and the response tasks as well as L1 reading comprehension scores and backward digit span were significant predictors of L2 reading scores. L1 low-level skills did not contribute significantly to L2 reading accuracy. Higher levels of reading-related anxiety were associated with slower reading, and L2 learners with concurrently lower levels of L1 and L2 reading ability needed more time to complete the reading test. These findings highlight that L2 reading tests should be flexibly timed so that everyone, including test takers with literacy-related difficulties such as dyslexia, can demonstrate their abilities.
We investigate the energy transfer from the mean profile to velocity fluctuations in channel flow by calculating nonlinear optimal disturbances, i.e. the initial condition of a given finite energy that achieves the highest possible energy growth during a given fixed time horizon. It is found that for a large range of time horizons and initial disturbance energies, the nonlinear optimal exhibits streak spacing and amplitude consistent with direct numerical simulation (DNS) at least at ${Re}_\tau = 180$, which suggests that they isolate the relevant physical mechanisms that sustain turbulence. Moreover, the time horizon necessary for a nonlinear disturbance to outperform a linear optimal is consistent with previous DNS-based estimates using eddy turnover time, which offers a new perspective on how some turbulent time scales are determined.
This note examines five passages of Cicero, De haruspicum responsis in light of the commented edition of A. Corbeill. New conjectures are offered on §§29 and 50; the transmitted text of §46 is defended; and a different interpretation of the text is offered at §§37 and 61.
A variety of larvae and parthenitae of trematodes have been detected in gastropods in the intertidal zone in Japan. However, because of the difficulty associated with the morphological identification of these stages, they have rarely been identified to the species or higher taxonomic levels. In this study, trematodes of these stages were sampled from intertidal gastropods in the Japanese coastal regions and were identified to the species, genus, or family levels morphologically and molecularly to elucidate or predict their life cycles. Investigation of 17 gastropod species (682 individuals in total) from 14 localities led to the detection of trematodes in 47 individuals belonging to six snail species. The infected gastropods were morphologically identified as Nipponacmea fuscoviridis, Monodonta confusa, Trochus sacellum, Batillaria attramentaria, Littorina brevicula, and Purpuradusta gracilis. Our molecular analyses revealed that sporocysts, rediae, and metacercariae from the gastropods were divided into 14 species belonging to nine families: Philophthalmidae, Fellodistomidae, Gymnophallidae, Lepocreadiidae, Heterophyidae, Opisthorchiidae, Notocotylidae, Microphallidae, and Opecoelidae. These trematodes were thought to use fishes, octopuses, seabirds, and marine mammals as their definitive hosts. Marine organisms such as jellyfishes, crustaceans, and fishes are also thought to act as the second intermediate and paratenic hosts of few present trematode species. As for the other trematode species, DNA barcodes of trematodes from various marine organisms will also illuminate the life cycles in future.
The secrecy of intelligence institutions might give the impression that intelligence is an ethics-free zone, but this is not the case. In The Ethics of National Security Intelligence Institutions, Adam Henschke, Seumas Miller, Andrew Alexandra, Patrick Walsh, and Roger Bradbury examine the ways that liberal democracies have come to rely on intelligence institutions for effective decision-making and look at the best ways to limit these institutions’ power and constrain the abuses they have the potential to cause. In contrast, the value of Amy Zegart’s and Miah Hammond-Errey’s research, in their respective books, Spies, Lies, and Algorithms: The History and Future of American Intelligence and Big Data, Emerging Technologies and Intelligence: National Security Disrupted, is the access each of them provides to the thoughts and opinions of the intelligence practitioners working in these secretive institutions. What emerges is a consensus that the fundamental moral purpose of intelligence institutions should be truth telling. In other words, intelligence should be a rigorous epistemic activity that seeks to improve decision-makers’ understanding of a rapidly changing world. Moreover, a key ethical challenge for intelligence practitioners in liberal democracies is how to do their jobs effectively in a way that does not undermine public trust. Measures recommended include better oversight and accountability mechanisms, adoption of a ‘risk of transparency’ principle, and greater understanding of and respect for privacy rights.
The brachyurans Tehuacana tehuacana Stenzel, 1944 and Dromilites americana Rathbun, 1935 have historically been difficult to place in families. A reevaluation of type and referred material from several institutions suggests that the two species are referrable to separate genera in Palaeoxanthopsidae. Hyphalocarcinus new genus is erected to accommodate H. americanus new combination, and Tehuacana remains a distinct genus. Palaeoxanthopsidae evolved and radiated in the Atlantic Ocean, ranging from Late Cretaceous (Maastrichtian) to early Eocene (Ypresian) in age. This work adds to the known diversity of Palaeoxanthopsidae and demonstrates that the family survived and thrived in the Atlantic Ocean in the wake of the end-Cretaceous extinction. Differential preservation of specimens must be evaluated carefully when placing superficially similar taxa at the family, genus, and species level.
Many aspects of migration policy involve hard moral dilemmas. Whether the dilemmas are concerned with refugee accommodation and integration, temporary labor migration, or the prospects of rejected asylum seekers, policymakers must sometimes make tough choices between competing and equally compelling moral values. Through in-depth discussion of various concrete examples, contributions to this roundtable argue that recognition and systematic analysis of the “ethics of migration policy dilemmas” can both increase philosophical and social-scientific understanding of public debates and policymaking on migration and provide ethical guidance for migration policy. Before introducing the roundtable’s individual contributions, this essay argues for the distinct epistemic value of the Dilemmas perspective by contrasting it with an approach that emphasizes the “busting” of myths; that is, the empirical uncovering of influential falsehoods in public and policy debates, often in the hope of improving policymaking through stronger evidence. We argue that while such myth busting can be valuable, it is insufficient and sometimes unhelpful for understanding how migration policy comes about and can be improved. Policymaking is not just shaped by empirical facts and understandings but also by interests and goals, including moral ones, that give empirical considerations deeper meaning and action-guiding potential. Often, these moral goals are numerous, similarly or equally compelling, and in profound tension with one another. Where this is the case, we should not simply introduce more and more accurate factual descriptions; we must also analyze dilemmas.
Moyamoya disease (MMD) is characterized by progressive carotid fork steno-occlusion and the development of “puff-of-smoke” collaterals on angiography. However, a subset of patients present with similar vascular changes but lack these hallmark collaterals, complicating both diagnosis and management. This “smokeless” phenotype, associated with ring finger protein 213 (RNF213) gene variants, challenges the traditional description of MMD. We describe a series of such patients who responded favorably to revascularization.
Methods:
In this ambispective observational study, we evaluated 12 patients with carotid fork steno-occlusive disease but without “puff-of-smoke” collaterals. Clinical, radiological and genetic assessments were assessed. Structural modeling of RNF213 protein variants was conducted through 3D homology modeling, validated via Ramachandran plots and further refined with COOT and PyMOL. Functional insights were derived through ConSurf analysis.
Results:
Of the 12 patients, 9 carried the RNF213 p.R4810K variant, 1 harboured a novel variant, 1 had both p.R4810K and a novel variant and 1 had p.R4859K. Initial misclassification as intracranial atherosclerosis or vasculitis led to inappropriate treatment. Following genetic confirmation, 9 patients underwent revascularization, with no stroke recurrence and a favorable clinical outcome. Structural modeling revealed minimal functional impact for the Val1529Met variant, whereas other variants significantly disrupted RNF213 stability and functionality.
Conclusions:
“Smokeless moyamoya,” characterized by carotid fork steno-occlusion without typical angiographic collaterals, represents a distinct clinical phenotype responsive to revascularization. RNF213 genetic screening enhances diagnostic precision, reshaping traditional paradigms and supporting tailored therapeutic approaches.
Behavioural activation (BA) is recommended for the treatment of depression but most research focuses on working age adults and there is a dearth of literature concerning the delivery of BA with people with co-occurring depression and mild cognitive impairment (MCI). This case study outlines a BA intervention with a male in his late 60s with depression and MCI and describes appropriate adaptations that were useful. Treatment consisted of psychoeducation of depression and BA, formulation, activity monitoring and scheduling, tackling self-critical thoughts and rumination, and relapse planning. The 12-session BA treatment resulted in a decrease in both depressive symptoms and psychological distress as well as an increase in the individual’s engagement with meaningful activities. This case study adds to the literature and strengthens the argument for the use of BA in the treatment of depression in older adults with MCI. Adaptations, conclusions and limitations are discussed.
Key learning aims
(1) To gain an understanding of the use of behavioural activation (BA) in the treatment of depression in older adults with mild cognitive impairment (MCI).
(2) To illustrate treatment of depression using BA with an older adult utilising the current evidence base.
(3) To outline adaptations that can be made to BA to help deliver this treatment with an older adult who has MCI.
On what policy areas and with what strategies should businesses and their leaders be involved in political activity? Advocates of “stakeholder capitalism” endorse companies and their leaders taking stances on social, environmental, and economic issues that advance the interests of their communities, not just of their shareholders. We juxtapose this view with two alternatives: companies and their leaders should a) stay out of politics or b) advocate only for their narrow business interests. We survey the mass public and business leaders. The public has little appetite for corporate leader engagement. However, business leaders, especially Democratic ones, endorse more active engagement from their firms on most issues, though they favor their firm leaders engaging in behind-the-scenes strategies rather than those that mobilize employees or customers. We find there is an elite appetite for business leaders to move beyond particularistic lobbying and to influence broader economic and social policy.
We prove the existence of a model companion of the two-sorted theory of c-nilpotent Lie algebras over a field satisfying a given theory of fields. We describe a language in which it admits relative quantifier elimination up to the field sort. Using a new criterion which does not rely on a stationary independence relation, we prove that if the field is NSOP$_1$, then the model companion is NSOP$_4$. We also prove that if the field is algebraically closed, then the model companion is c-NIP.