A quirky truth is that the oldest biomarker findings are largely metabolic. These had minimal impact on contemporary thought and research and were largely ignored. They have been rediscovered and validated almost 100 years later, informing our understanding of neurobiology and medical comorbidity and spurring contemporary treatment discovery efforts.

We investigate the existence of 4-torsion in the integral cohomology of oriented Grassmannians. We establish bounds on the characteristic rank of oriented Grassmannians and prove some cases of our previous conjecture on the characteristic rank. We also discuss the relation between the characteristic rank and a result of Stong on the height of w1 in the cohomology of Grassmannians. The existence of 4-torsion classes follows from the results on the characteristic rank via Steenrod square considerations. We thus exhibit infinitely many examples of 4-torsion classes for oriented Grassmannians. We also prove bounds on torsion exponents of oriented flag manifolds. The article also discusses consequences of our results for a more general perspective on the relation between the torsion exponent and deficiency for homogeneous spaces.

This paper investigates Korean nominal coordination, a distant conjunct of which is semantically incompatible with the subcategorizing verb in a sentence. This type of nominal coordination is supported by both corpus-based and experimental data. Such coordinations pose a challenge to previous approaches to coordination in the literature. Specifically, any theory directly linking the subcategorizing verb to such a distant conjunct encounters the issue of semantic incompatibility. To address this issue, based on Lee (2020), I propose associating the distant conjunct with a direct hypernym of the verb. While the primary focus is on conjunctive nominal coordinations, the hypothesis also extends to disjunctive nominal coordinations. This semantic taxonomy-based account is then formally implemented in Head-driven Phrase Structure Grammar (Pollard & Sag 1994; Sag et al. 2003), adapting the generalized conjunction from Partee & Rooth (1983). Furthermore, I argue that this analysis can serve as a basis for explaining other related constructions in Korean.

We explore the surprising lexical be construction in English (e.g. Why don’t you be quiet?). After an overview of previous discussions, an investigation of the use of lexical be in the COCA and SOAP corpora is provided. It is shown that its distribution is highly skewed and that it is completely felicitous only under a very limited set of conditions. An account of lexical be is then provided showing that the conditions that license it are inherited from more general constructions, most importantly the negative imperative construction and the ‘Why don’t you’ construction. In this light, it is suggested that the lexical be construction, with its special properties, provides strong evidence for a constructional approach to linguistic competence along the lines of Goldberg (1995), Culicover and Jackendoff (2005), Sag (2012).

A rare silver mineral, dervillite (ideally Ag2AsS2), has been found in specimens from the famous Jáchymov mining district, Czech Republic. It occurs as very rare long-prismatic crystals up to 0.4 mm across in association with proustite, bismuth and native silver in the thin arsenic veinlets within the Trojická vein (Svornost mine). Dervillite is monoclinic, space group Pc, with a = 9.6375(3), b = 12.9462(4), c = 6.8497(2) Å, β = 99.510(2)° and V = 842.88(2) Å3 (Z = 8). The new structure refinement, R1 = 2.94% for 18767 reflections with [I > 3σ(I)] and wR2 = 7.93% for all 20050 reflections, provided a better fit to the data compared to earlier studies, revealing that silver (8 symmetrically independent atomic sites), which adopts various coordinations (from quasi-linear to tetrahedral) in the structure of dervillite vibrates non-harmonically at room temperature. The Gram-Charlier development, describing the atomic displacement parameters of silver atoms, was used to model their non-harmonic behaviour. A discussion on the use of the approach to the data with limited quality is also provided.

This article studies the rise and fall of commercial aviation in Iran, then known as Persia, between 1923 and 1932. Two airlines, the German Junkers Luftverkehr AG and Britain’s Imperial Airways, invested significant time and effort in developing air routes but eventually failed due to financial hardship and political intransigence. Exploring this erratic development, the article has two aims: first, to investigate the entangled history of two of the world’s oldest airlines and the challenges they navigated; and second, to assess the fraught relationship between state and business interests. The German and British airlines were rivals in Iran, but they became partly dependent on each other. Both airlines suffered from the global political dynamics of the interwar period while Junkers, in particular, also struggled financially. Meanwhile, the Iranian state had yet to decide whether to view the new technology with enthusiasm or concern. Its ambivalent and reluctant reaction had profound effects on the trajectories of Junkers and Imperial Airways. Assessing the capability of a nascent airline industry to develop viable business models outside of Europe, the article also serves as a case study revealing the headwinds airlines encountered in the earliest phase of commercial aviation.

The so-called credibility revolution dominates empirical economics, with its promise of causal identification to improve scientific knowledge and ultimately policy. By examining the case of rural electrification in the Global South, this opinion paper exposes the limits of this evidence-based policy paradigm. The electrification literature boasts many studies using the credibility revolution toolkit, but at the same time, several systematic reviews demonstrate that the evidence is divided between very positive and muted effects. This bifurcation presents a challenge to the science-policy interface, where policymakers, lacking the resources to sift through the evidence, may be drawn to the results that serve their (agency's) interests. The interpretation is furthermore complicated by unresolved methodological debates circling around external validity as well as selective reporting and publication decisions. These features, we argue, are not particular to the electrification literature but inherent to the credibility revolution toolkit.

This study aimed to create a risk prediction model with artificial intelligence (AI) to identify patients at higher risk of postpartum hemorrhage using perinatal characteristics that may be associated with later postpartum hemorrhage (PPH) in twin pregnancies that underwent cesarean section. The study was planned as a retrospective cohort study at University Hospital. All twin cesarean deliveries were categorized into two groups: those with and without PPH. Using the perinatal characteristics of the cases, four different machine learning classifiers were created: Logistic regression (LR), support vector machine (SVM), random forest (RF), and multilayer perceptron (MLP). LR, RF, and SVM models were created a second time by including class weights to manage the underlying imbalances in the data. A total of 615 twin pregnancies were included in the study. There were 150 twin pregnancies with PPH and 465 without PPH. Dichorionity, PAS, and placenta previa were significantly higher in the PPH-positive group (p = .045, p = .004, p = .001 respectively). In our model, LR with class weight was the best model with the highest negative predictive value. The AUC in our LR with class weight model was %75.12 with an accuracy of 70.73%, a PPV of 47.92%, and an NPV of 85.33% in our data. Although the application of machine learning to create predictive models using clinical risk factors and our model’s 70% accuracy rate are encouraging, it is not sufficient. Machine learning modeling needs further study and validation before being incorporated into clinical use.

We examine the role of fragmentation of information in explaining the dynamics of sectoral inflation. Using the quarterly survey of firms’ prices and costs in Japan, we first document two empirical facts: the sensitivity of sectoral inflation to changes in sectoral costs monotonically decreases with the dispersion of changes in (i) current costs and (ii) those in the past. A direct application of the dispersed information model can reconcile the fact (i) but fails to reconcile the fact (ii). We then extend the standard imperfect information model to construct a dynamic general equilibrium model that features fragmentation of information, wherein a finite number of groups of firms exist and firms in the same group share common idiosyncratic noises in their signals. Using this model, we find that the degree of fragmentation of information plays a crucial role in explaining these empirical facts.

Diamonds are found occasionally in the United States of America. Diamonds from the Prairie Creek lamproite in Arkansas, USA occur within a north to south corridor of Neoproterozoic-to-mid-Cretaceous magmatism that extends across North America. These diamond-bearing lamproites are unusual because they intrude adjacent to sutured and strongly thinned lithosphere rather than stable within-plate settings and the diamonds themselves provide physical evidence of processes related to diamond formation at the cratonic margin. Indeed, A review of previously published geophysical data, isotopic compositions, inclusion suites and inclusion geochemistry suggest most diamonds were formed in subducted and eclogitic rocks within a highly localised diamondiferous lithosphere beneath the cratonic margin.

The morphology and spectroscopic character of 155 diamonds from the Prairie Creek lamproite suggest typical diamond formation conditions in an otherwise thinned continental lithosphere. Most diamonds examined during this investigation have spectroscopic features indicating strong nitrogen aggregation, a history of thermal perturbation and plastic deformation. Nitrogen contents range up to 1882 ppm and the diamonds preserve ∼70% aggregated nitrogen in the B aggregation state. Furthermore, inclusion elastic barometry and time-averaged mantle residence temperatures suggest most Arkansas diamonds formed at 5.2±0.2 GPa and 1205±63°C (1σ). However, a subpopulation of ∼4% of relatively large and inclusion free, colourless, flattened-to-irregular habit Arkansas diamonds are Type IIa with <5 at.ppm nitrogen. Those stones size, morphology, colour and N content might warrant their inclusion in the class of Cullinan-like, Large, Inclusion-Poor, Pure, Irregular and Resorbed or ‘CLIPPIR’ diamonds. Other diamonds examined commonly exhibit physical evidence of plastic deformation, including brown body colour and deformation lamellae.

We define oriented Temperley–Lieb algebras for Hermitian symmetric spaces. This allows us to explain the existence of closed combinatorial formulae for the Kazhdan–Lusztig polynomials for these spaces.

W. V. Quine suggests that meaning derives from the stimulus, the effects of the outside world on the subject’s nerve endings. However, the idiosyncrasy of the stimulus poses challenges to the intersubjectivity of meaning. Gary Kemp proposes the stimulus field approach as a solution. The stimulus field approach focuses on the forces affecting the subject, rather than the effects on the subject. In this article, I critique Kemp’s solution. Furthermore, I argue that the Quinean approach can be refined in a way that two agents may converge on the same meaning even without sharing the same stimuli or forces affecting them.

Philosophers have struggled to explain the mismatch of emotions and their objects across time, as when we stop grieving or feeling angry despite the persistence of the underlying cause. I argue for a sceptical approach that says that these emotional changes often lack rational fit. The key observation is that our emotions must periodically reset for purely functional reasons that have nothing to do with fit. I compare this account to David Hume’s sceptical approach in matters of belief, and conclude that resistance to it rests on a confusion similar to one that he identifies.