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Bagrada bug, Bagrada hilaris (Burmeister) (Hemiptera: Pentatomidae), is an invasive pest of cole crops in the United States. Because it also feeds on widespread weeds and persists in natural habitats surrounding crop fields, conventional control strategies are often ineffective at providing long-term control. One egg parasitoid, Gryon aetherium Talamas (Hymenoptera: Scelionidae), is a promising biological control candidate because of its ability to parasitise B. hilaris buried eggs. Recently, adventive populations of G. aetherium were recovered from sentinel eggs in California along with a native egg parasitoid, Ooencyrtus californicus Girault (Hymenoptera: Encyrtidae). A better understanding of these parasitoid species’ spatial preference for foraging and their possible competitive interactions will help evaluate their host suppression potential. We compared the foraging abilities of these two parasitoid species for eggs deposited below and above ground. We also investigated the effect of interspecific competition on host suppression and the ability of O. californicus to parasitise eggs previously parasitised by G. aetherium. G. aetherium parasitised naturally and manually buried eggs, whereas O. californicus did not. In another experiment, O. californicus parasitised eggs glued to cards, but not in the presence of sand. Results suggest that G. aetherium may be negatively affected by the presence of O. californicus, and there was a slight but significant reduction in total host mortality when the parasitoids were present together. However, the inability of O. californicus to forage in soil likely limits negative interactions between these two species, and the two parasitoids may ultimately complement each other.
Let H be a real Hilbert space and $\Phi :H\to H$ be a $C^1$ operator with Lipschitzian derivative and closed range. We prove that $\Phi ^{-1}(0)\neq \emptyset $ if and only if, for each $\epsilon>0$, there exist a convex set $X\subset H$ and a convex function $\psi :X\to \mathbf {R}$ such that $\sup _{x\in X}(\|x\|^2+\psi (x))-\inf _{x\in X}(\|x\|^2+\psi (x))<\epsilon $ and $0\in \overline {{\mathrm {conv}}}(\Phi (X))$.
In this paper, we study the embedding problem of an operator into a strongly continous semigroup. We obtain characterizations for some classes of operators, namely composition operators and analytic Toeplitz operators on the Hardy space $H^2$. In particular, we focus on the isometric ones using the necessary and sufficient condition observed by T. Eisner.
For precision-required robot operations, the robot’s positioning accuracy, repeatability, and stiffness characteristics should be considered. If the mechanism has the desired repeatability performance, a kinematic calibration process can enhance the positioning accuracy. However, for robot operations where high accelerations are needed, the compliance characteristics of the mechanism affect the trajectory-tracking accuracy adversely. In this paper, a novel approach is proposed to enhance the trajectory-tracking accuracy of a robot operating at high accelerations by predicting the compliant displacements when there is no physical contact of the robot with its environment. Also, this case study compares the trajectory-tracking characteristics of an over-constrained and a normal-constrained 2-degrees-of-freedom (DoF) planar parallel mechanism during high-acceleration operations up to 5 g accelerations. In addition, the influence of the end-effector’s center of mass (CoM) position along the normal of the plane is investigated in terms of its effects on the proposed trajectory-enhancing algorithm.
Recent theories have implicated inflammatory biology in the development of psychopathology and maladaptive behaviors in adolescence, including suicidal thoughts and behaviors (STB). Examining specific biological markers related to inflammation is thus warranted to better understand risk for STB in adolescents, for whom suicide is a leading cause of death.
Method:
Participants were 211 adolescent females (ages 9–14 years; Mage = 11.8 years, SD = 1.8 years) at increased risk for STB. This study examined the prospective association between basal levels of inflammatory gene expression (average of 15 proinflammatory mRNA transcripts) and subsequent risk for suicidal ideation and suicidal behavior over a 12-month follow-up period.
Results:
Controlling for past levels of STB, greater proinflammatory gene expression was associated with prospective risk for STB in these youth. Similar effects were observed for CD14 mRNA level, a marker of monocyte abundance within the blood sample. Sensitivity analyses controlling for other relevant covariates, including history of trauma, depressive symptoms, and STB prior to data collection, yielded similar patterns of results.
Conclusions:
Upregulated inflammatory signaling in the immune system is prospectively associated with STB among at-risk adolescent females, even after controlling for history of trauma, depressive symptoms, and STB prior to data collection. Additional research is needed to identify the sources of inflammatory up-regulation in adolescents (e.g., stress psychobiology, physiological development, microbial exposures) and strategies for mitigating such effects to reduce STB.
When one fluid is injected into a confined geometry such as a porous medium filled with another immiscible fluid, even at an extremely low injection speed, rapid filling of several pore spaces accompanied by retraction of multiple fluid–fluid interfaces can be observed. Such processes with fast liquid redistribution within the solid structure, called Haines jumps, are ubiquitous in many multiphase flow systems, which can impact fluid trapping, energy dissipation and hysteretic saturation in various engineering applications. Inspired by this mechanism, here, we propose a dual-channel structure to realise controlled Haines jumps during fluid displacement processes. Via theoretical analysis and numerical simulations, we show that the dynamics of fluid interfaces during Haines jumps can be quantitatively correlated with the driving capillary pressure and dissipating viscous stress, which enables simultaneous determination of the fluid viscosity and interfacial tension in the dual-channel multiphase system.
Pummelo is the largest citrus species in the Rutaceae family and is important for human health and nutrition. This fruit is underutilized and threatened by human activities in its natural habitat. The present research was conducted in the Devanahalli region of Karnataka, which has a vast diversity of pummelo. This study aimed to evaluate 40 pummelo genotypes, selected through a preliminary survey, using morphological, biochemical and sensory assessments. Fruit and pulp weights ranged from 344.03 to 1746.23 g and 194.39 to 1073.07 g, with mean values of 939.67 and 522.81 g, respectively. Traits such as fruit length, diameter, fruit axis diameter, fruit volume, number of segments, rind thickness, fruit, pulp, peel weight, seed weight and seeds per fruit showed highly significant differences. Biochemical analysis revealed that ascorbic acid content varied from 28.53 to 60 mg/100 g, titratable acidity from 0.73 to 2.07% and total soluble solids from 7.63 to 11.07°Brix. High phenol (55.08–166.17 mg GAE/g FW) and flavonoid (39.26–137.78 mg CE/g FW) content were observed in fruit pulp, indicating significant antioxidant potential. Several morphological and biochemical traits exhibited significant positive correlations. A slightly higher phenotypic coefficient of variation was found for all the characters compared to the corresponding genotypic coefficient of variation. The principal component analysis indicated that the first nine components contributed 94.24% of the total variation. Hierarchical cluster analysis divided the populations into two distinct clusters. Sensory analysis indicated that genotypes, DVP-1 and DVP-2 had higher acceptability rates. The significant variations in plant traits among the genotypes offer great chances to select the best ones for genetic improvement programmes.
During the COVID-19 pandemic, free on-demand testing was promoted in the US. This study was undertaken to support or refute the hypothesis that negative SARS-CoV-2 tests led to travel that exposed travelers to the virus in US states.
Methods
Data on daily trips outside households based on cell phone movement were matched by date to negative tests, positive tests, subsequent COVID-19 cases, and deaths lagged at various intervals in 49 US states during the first 16 months of the pandemic. Least-squares regression of weekly trips as a function of prior trips, negative tests, and cases was examined. Cases 10-14 days after negative tests and deaths 20-25 days later as a function of previous trips and positive tests were also assessed by least squares regression.
Results
Increases in negative tests predicted increases in trips but trips declined as cases increased. Changes in trips predicted short-term changes in cases and deaths. The data closely fit the models.
Conclusions
Surges in cases and deaths from COVID-19 were likely a partial result of on-demand testing, without sufficient contact tracing and quarantine, which misled those who tested negative into thinking that it was safe to travel.
We investigate nonlinear energy transfer for channel flows at friction Reynolds numbers $Re_{\tau }=180$ and $590$. The key feature of the analysis is that we quantify the energy transferred from a source mode to a recipient mode, with each mode characterised by a streamwise wavenumber and a spanwise wavenumber. This is achieved through an explicit examination of the triadic interactions of the nonlinear energy transfer term in the spectral turbulent kinetic energy equation. First, we quantify the nonlinear energy transfer gain and loss for individual Fourier modes. The gain and loss cannot be obtained without expanding the nonlinear triadic interactions. Second, we quantify the nonlinear energy transfer budgets for three types of modes. Each type of mode is characterised by a specific region in streamwise–spanwise wavenumber space. We find that a transverse cascade from streamwise-elongated modes to spanwise-elongated modes exists for all three types of modes. Third, we quantify the forward and inverse cascades between resolved scales and subgrid scales in the spirit of large-eddy simulations. For the cutoff wavelength range that we consider, the forward and inverse cascades between the resolved scales and subgrid scales result in a net forward cascade from the resolved scales to the subgrid scales. The shape of the net forward cascade curve with respect to the cutoff wavelength resembles the net forward cascade predicted by the Smagorinsky eddy viscosity.
This paper proposes a mobile robot recovery mechanism for low-cost robotic systems due to vision sensor failure in vSLAM systems. The approach takes advantage of ROS architecture and adopts the Shannon Nyquist sampling theory to selectively sample path parameters that will be used for back travel in case of vision sensor failure. As opposed to point clouds normally used to store vSLAM data, this paper proposes to store and use lightweight variables namely distance between sampled points, velocity combinations, i.e., linear and angular velocity, sampled period, and yaw angle values to describe the robot path and reduce the memory space required to store these variables. In this study, low-cost robotic systems typically using cameras aided by proprioceptive sensors such as IMU during vSLAM activities are investigated. A demonstration is made on how the ROS architecture can be used in a scenario where vision sensing is adversely affected, resulting in mapping failure. Additionally, a recommendation is made for adoption of the approach for vSLAM platforms implemented on both ROS1 and ROS2. Furthermore, a proposal is made to add an additional layer to vSLAM systems that will be exclusively used for back travel in case of vision loss during vSLAM activities resulting in mapping failure.
Significant differences in life-history traits between the southern population (S) and northern (N) population of the cabbage beetle Colaphellus bowringi make it an excellent model for studying inheritance in this insect. In the present study, we observed the life-history traits of pure strains, F1, reciprocal backcross and reciprocal F2 progeny under a photoperiod of L:D 15:9 h at 22 °C. The S population had shorter larval development time, longer pupal time, higher body weight, growth rate and weight loss compared with the N population. In the F1 testing, the larval development time and body weight in hybrid populations were intermediate between the parents, and the paternal parents played a greater role in determining the larval development time, while the maternal parents exhibited a greater role in determining the body weight. The pupal time of hybrid populations was significantly shorter than that of the parents. In the reciprocal backcross testing, both father and grandfather affected the larval development time, while both mother and grandmother affected the body weight. Consistently, in the reciprocal F2 cross testing, the grandfather was more influential in determining the larval development time, and grandmother was more important in determining the body weight. In all tested populations, females had greater body weight, higher growth rate and weight loss than males. Hybridization pattern did not affect sex dimorphism and sex ratio. Overall, these findings suggest that different pathways (maternal or paternal effects) were involved in the inheritance of various life-history traits in C. bowringi.
Urgent care centers (UCCs) have reported high rates of antibiotic prescribing for acute respiratory tract infections. Prior UCC studies have generally been limited to single networks. Broadly generalizable stewardship efforts targeting common diagnoses are needed. This study examines the effectiveness of an antibiotic stewardship intervention in reducing inappropriate prescribing for bronchitis and viral upper respiratory tract infections (URTIs) in UCCs.
Design:
A quality improvement study comparing inappropriate antibiotic prescribing rates in UCCs after the introduction of an antibiotic stewardship intervention.
Setting:
Forty-nine UCCs in 27 different networks from 18 states, including 1 telemedicine site.
Participants:
Urgent care clinicians from a national collaborative of UCCs, all members of the Urgent Care Association.
Methods:
The intervention included signing a commitment statement and selecting from 5 different intervention options during 3 plan-do-study-act cycles. The primary outcome was the percentage of urgent care encounters for viral URTIs or bronchitis with inappropriate prescribing, stratified by clinician engagement and diagnosis. A 3-month baseline and 9-month intervention period were compared using a regression model using a generalized estimating equation.
Results:
Among 15,385 encounters, the intervention was associated with decreases in inappropriate antibiotic prescribing for bronchitis (48% relative decrease, aOR = 0.52; 95% CI, 0.33–0.83) and viral URTIs (33%, aOR = 0.67; 95% CI, 0.55–0.82) among actively engaged clinicians compared to baseline. The intervention did not result in significant changes for clinicians not actively engaged.
Conclusions:
This intervention was associated with reductions in inappropriate prescribing among actively engaged clinicians. Implementing stewardship interventions in UCCs may reduce inappropriate antibiotic prescriptions for common diagnoses; however, active clinician engagement may be necessary.
The Wolff–Parkinson–White pattern is a delta wave frequently detected in school-based cardiovascular screening programs in Japan. Although most children with Wolff–Parkinson–White pattern are asymptomatic, initial symptoms may include syncope or sudden death, necessitating accurate diagnosis and management. Delta waves can also indicate a fasciculoventricular pathway, which poses no risk and does not require management.
Methods:
We reviewed the medical records of patients referred to our hospital between April 2008 and March 2022 to evaluate the electrocardiographic signs of the Wolff–Parkinson–White pattern. The existence of Wolff–Parkinson–White syndrome and fasciculoventricular pathway were determined based on atrioventricular block and QRS waveform changes after adenosine administration during sinus rhythm.
Results:
The study cohort included 127 children (65 males; median age: 12.8 years, resting heart rate: 75 beats/min, PR interval: 109 ms, and QRS duration: 101 ms). The adenosine administration test revealed a fasciculoventricular pathway, Wolff–Parkinson–White syndrome, and indeterminate findings in 64, 54, and 9 children, respectively. More than 60% of children with a QRS duration ≤ 120 ms had a fasciculoventricular pathway. Age ≤ 12 years, QRS duration >120 ms, and type A category (children with R/S ratios >1 in lead V1) were identified as independent risk factors for Wolff–Parkinson–White syndrome. No adverse events were observed in any child.
Conclusions:
The adenosine administration test is safe and feasible for differentiating Wolff–Parkinson–White syndrome from fasciculoventricular pathways and can reduce the unnecessary management of children with fasciculoventricular pathways.
The genus Enenterum Linton, 1910 comprises species which parasitize herbivorous kyphosid fish. In the present study, a new species is described based on fresh specimens collected from Kyphosus incisor from Rio de Janeiro. The new species is characterized by having the oral sucker infundibuliform with 10 lobes, prepharynx two times longer than pharynx, presence of oesophagus, testes slightly lobed, round ovary and rectum with muscular sphincter connected to the anus. New genetic sequences include partial 18S and 28S rDNA and ITS1-5.8S-ITS2. The phylogenetic analyses place Enenterum gomesae n. sp. as sister of Enenterum aureum, corroborating the morphological analyses. Enenterum aureum (=E. pimelopteri) previously described from Kyphosus spp. from Rio de Janeiro is now considered E. gomesae n. sp. The new species represents the only South American species so far described for this genus.
Anxiety disorders and treatment-resistant major depressive disorder (TRD) are often comorbid. Studies suggest ketamine has anxiolytic and antidepressant properties.
Aims
To investigate if subcutaneous racemic ketamine, delivered twice weekly for 4 weeks, reduces anxiety in people with TRD.
Method
The Ketamine for Adult Depression Study was a multisite 4-week randomised, double-blind, active (midazolam)-controlled trial. The study initially used fixed low dose ketamine (0.5 mg/kg, cohort 1), before protocol revision to flexible, response-guided dosing (0.5–0.9 mg/kg, cohort 2). This secondary analysis assessed anxiety using the Hamilton Anxiety (HAM-A) scale (primary measure) and ‘inner tension’ item 3 of the Montgomery–Åsberg Depression Rating Scale (MADRS), at baseline, 4 weeks (end treatment) and 4 weeks after treatment end. Analyses of change in anxiety between ketamine and midazolam groups included all participants who received at least one treatment (n = 174), with a mixed effects repeated measures model used to assess the primary anxiety measure. The trial was registered at www.anzctr.org.au (ACTRN12616001096448).
Results
In cohort 1 (n = 68) the reduction in HAM-A score was not statistically significant: −1.4 (95% CI [−8.6, 3.2], P = 0.37), whereas a significant reduction was seen for cohort 2 (n = 106) of −4.0 (95% CI [−10.6, −1.9], P = 0.0058), favouring ketamine over midazolam. These effects were mediated by total MADRS and were not maintained at 4 weeks after treatment end. MADRS item 3 was also significantly reduced in cohort 2 (P = 0.026) but not cohort 1 (P = 0.96).
Conclusion
Ketamine reduces anxiety in people with TRD when administered subcutaneously in adequate doses.
We argue that libertarianism (roughly, the thesis that we have indeterministic, libertarian free will) is compatible with God’s infallible foreknowledge. We use eternalism (roughly, the thesis that reality is a 4-dimensional block and that past, present, and future objects exist) as an explanatory stepping stone between libertarianism and God’s foreknowledge: eternalism entails that (and comes close to explaining how) an omniscient God would know what we decide in the future even if we have libertarian free will. This account also explains what is wrong with standard fatalist arguments for the incompatibility of free will and God’s foreknowledge.
Dark patterns have become a pervasive issue around the world. However, Indonesia has not taken any action to deal with the situation. This article aims to analyse the issue of dark patterns in digital platforms from Indonesia’s consumer protection law perspective. It contends that Indonesia’s consumer protection law is not adequate in overcoming the issue of dark patterns in digital platforms. Several laws regulate basic principles and provisions that indirectly prohibit dark patterns, but these regulations can only be applied to certain forms of dark patterns and are difficult to implement. The article suggests that Indonesia must specifically regulate the prohibition of the practices of dark patterns in its current law. The regulations do not have to define the term “dark patterns” directly; however, they should expressly regulate prohibitions against the practice of using design interfaces in a way that subverts or impairs consumers’ autonomy and/or exploits consumers’ behavioural biases.
This study is designed to understand embarrassment in the second/foreign language (L2) context. Following a mixed-method design, in Phase 1, a sample of 141 tertiary-level Austrian English language learners were asked to write a narrative about their experiences of embarrassment in their language learning histories. Analyzing the narratives showed that L2 embarrassment is a multidimensional construct that is frequently experienced by a range of language learners. In Phase 2, we developed and validated an L2 classroom speaking embarrassment (L2CSE) scale among a sample of 402 international English language learners drawing on the literature and analysis of the narratives. Data showed that L2 embarrassment is best represented by a bifactor exploratory structural equation model, capturing both general and specific aspects of L2 embarrassment. We found that a supportive classroom environment and fostering a growth mindset can decrease the risk of L2 embarrassment. As expected, L2 embarrassment was a negative predictor of willingness to communicate and self-perceived language proficiency. These initial findings suggest that L2 embarrassment could be an important and influential emotion in the language learning classroom context which requires further research.