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Building on the sensitization hypothesis, the present work aimed to examine how parent-adolescent conflict might be associated with heightened emotional reactivity to peer conflicts, which in turn shape the development of adolescent internalizing psychopathology. Participants were 108 Taiwanese adolescents between the ages of 18 and 19 (Mage = 18.53, SDage = 0.39; 64% female) who completed baseline assessments, 14-day daily surveys, and 6-month follow-up assessments. Emotional reactivity was measured by calculating the daily association between peer conflict and positive and negative emotions. Results indicated that greater baseline parent-adolescent conflict was associated with higher negative emotional reactivity to peer conflicts, which then predicted increased depressive symptoms and anxiety symptoms 6 months later. Moreover, greater positive emotional reactivity to peer conflicts (i.e., more declines in positive emotions in response to peer conflicts) predicted increased depressive symptoms. Thus, the findings of the current study support and extend the sensitization hypothesis and suggest that parent-adolescent conflict may contribute to family-of-origin sensitization in non-familial, interpersonal contexts. The results have key implications for understanding adolescent developmental psychopathology associated with family conflicts and emotional reactivity.
This is a foundation for algebraic geometry, developed internal to the Zariski topos, building on the work of Kock and Blechschmidt (Kock (2006) [I.12], Blechschmidt (2017)). The Zariski topos consists of sheaves on the site opposite to the category of finitely presented algebras over a fixed ring, with the Zariski topology, that is, generating covers are given by localization maps for finitely many elements $f_1,\dots, f_n$ that generate the ideal $(1)=A\subseteq A$. We use homotopy-type theory together with three axioms as the internal language of a (higher) Zariski topos. One of our main contributions is the use of higher types – in the homotopical sense – to define and reason about cohomology. Actually computing cohomology groups seems to need a principle along the lines of our “Zariski local choice” axiom, which we justify as well as the other axioms using a cubical model of homotopy-type theory.
This article looks at Topkapı Palace as a showcase reflecting the changing cultural heritage policies of the Allies, as well as of the İstanbul and Ankara governments, during the occupation of İstanbul from 1918 to 1923. It analyzes the military, archaeological, and cultural facets of the occupation, focusing first on the military takeover of the Topkapı gardens, then on the French archaeological mission at the Seraglio, and finally on conflicts over the possession of the imperial treasures and sacred relics. Drawing on primary sources from Ottoman, Turkish, French, and British archives, memoirs, letters, newspapers, and visual material, this article explores the versatility of cultural heritage policies during the occupation and the entangled relations among various power groups, institutions, and actors. The military, strategic, cultural, and historical significance of the royal complex, together with its invaluable imperial collections, made the historic palace a place of rivalry and contestation, as well as deception and cooperation, among various agents and actors, including the Ottoman military and bureaucratic officials, local and foreign archaeologists, the dynastic family, the Interallied government, the occupation forces, and the Turkish resistance forces, ultimately reflecting the military and political empowerment of Ankara.
This editorial highlights increasing prevalence and treatment rates of apparently disparate disorders. We ask whether cross-disorder factors including greater mental health literacy, social media and a shift to psychiatric explanations for distress contribute to these trends. We highlight a consequence: the changing doctor–patient relationship and its impacts.
In this study we investigate the sedimentation of prolate spheroids in a quiescent fluid by means of the particle-resolved direct numerical simulation. With the increase of the particle volume fraction $\phi$ from $0.1\,\%$ to $10\,\%$, we observe a non-monotonic variation of the mean settling velocity of particles, $\langle V_s \rangle$. By virtue of the Voronoi analysis, we find that the degree of particle clustering is highest when $\langle V_s \rangle$ reaches the local maximum at $\phi =1\,\%$. Under the swarm effect, clustered particles are found to preferentially sample downward fluid flows in the wake regions, leading to the enhancement of the settling speed. As for lower or higher volume fractions, the tendency of particle clustering and the preferential sampling of downward flows are attenuated. The hindrance effect becomes predominant when the volume fraction exceeds 5 % and reduces $\langle V_s \rangle$ to less than the isolated settling velocity. Particle orientation plays a minor role in the mean settling velocity, although individual prolate particles still tend to settle faster in suspensions when they deviate more from the broad-side-on alignment. Moreover, we also demonstrate that particles are prone to form column-like microstructures in dilute suspensions under the effect of wake-induced hydrodynamic attractions. The radial distribution function is higher at a lower volume fraction. As a result, the collision rate scaled by the particle number density decreases with the increasing volume fraction. By contrast, as another contribution to the particle collision rate, the relative radial velocity for nearby particles shows a minor degree of variation due to the lubrication effect.
The clinical high risk for psychosis (CHR-p) syndrome enables early identification of individuals at risk of schizophrenia and related disorders. We differentiate between the stigma associated with the at-risk identification itself (‘labelling-related’ stigma) versus stigma attributed to experiencing mental health symptoms (‘symptom-related’ stigma) and examine their relationships with key psychosocial variables.
Aims
We compare labelling- and symptom-related stigma in rates of endorsement and associations with self-esteem, social support loss and quality of life.
Method
We assessed stigma domains of shame-related emotions, secrecy and experienced discrimination for both types of stigma. Individuals at CHR-p were recruited across three sites (N = 150); primary analyses included those who endorsed awareness of psychosis risk (n = 113). Paired-sample t-tests examined differences in labelling- versus symptom-related stigma; regressions examined associations with psychosocial variables, controlling for covariates, including CHR-p symptoms.
Results
Respondents reported greater symptom-related shame, but more labelling-related secrecy. Of the nine significant associations between stigma and psychosocial variables, eight were attributable to symptom-related stigma, even after adjusting for CHR-p symptoms.
Conclusions
Stigma attributed to symptoms had a stronger negative association with psychosocial variables than did labelling-related stigma among individuals recently identified as CHR-p. That secrecy related to the CHR-p designation was greater than its symptom-related counterpart suggests that labelling-related stigma may still be problematic for some CHR-p participants. To optimise this pivotal early intervention effort, interventions should address the holistic ‘stigmatising experience’ of having symptoms, namely any harmful reactions received as well as participants’ socially influenced concerns about what their experiences mean, in addition to the symptoms themselves.
The introduction of algorithms in courts is currently the object of much scrutiny, attempting to find balance between increasing efficiency to the legal system and avoiding associated risks. This paper aims to explore how the judiciary organisations responsible for implementing algorithms describe the temporal demands of continuity and change, through a case-study of the Brazilian National Council of Justice (CNJ). Through its centralised, collaborative and open-access based platform, the CNJ views algorithms as a necessary step to deal with excessive case-load, and as a rationality-instituting mechanism for a currently dysfunctional situation. It attempts to deal with risks of disruption by placing itself in a supervisory role regarding all algorithms developed by courts across the country, ensuring the quality of the data and excluding the moment of judicial decision-making from automation, but this does not exclude the representation of the new technology as an instrument to implement specific doctrinal positions.
The social and political contexts in many countries are affected by dangerous trends and forces of populism. Populist hostility is most observable in connection with issues of immigration, where it functions as a pretext for scrapping legal protections in increasingly hostile immigration laws. What is particularly insidious about these developments is the claim, articulated by some theorists, that the popular resentment and backlash against immigrants and refugees are justified. That populists are hostile towards immigrants and human rights laws, the claim seems to go, is the fault of the legal norms and institutions that allow in the immigrants and protect them. This article challenges those approaches and argues that legal constraints on popular biases towards immigrants are necessary and need to be defended against popular moralism. It is also argued that although community values are important, they should not be considered as trumps against the rights of immigrants and refugees.
We study the generation, nonlinear development and secondary instability of unsteady Görtler vortices and streaks in compressible boundary layers exposed to free-stream vortical disturbances and evolving over concave, flat and convex walls. The formation and evolution of the disturbances are governed by the compressible nonlinear boundary-region equations, supplemented by initial and boundary conditions that characterise the impact of the free-stream disturbances on the boundary layer. Computations are performed for parameters typical of flows over high-pressure turbine blades, where the Görtler number, a measure of the curvature effects, and the disturbance Reynolds number, a measure of the nonlinear effects, are order-one quantities. At moderate intensities of the free-stream disturbances, increasing the Görtler number renders the boundary layer more unstable, while increasing the Mach number or the frequency stabilises the flow. As the free-stream disturbances become more intense, vortices over concave surfaces no longer develop into the characteristic mushroom-shaped structures, while the flow over convex surfaces is destabilised. An occurrence map identifies Görtler vortices or streaks for different levels of free-stream disturbances and Görtler numbers. Our calculations capture well the experimental measurements of the enhanced skin friction and wall-heat transfer over turbine-blade pressure surfaces. The time-averaged wall-heat transfer modulations, termed hot fingers, are elongated in the streamwise direction and their spanwise wavelength is half of the characteristic wavelength of the free-stream disturbances. Nonlinearly saturated disturbances are unstable to secondary high-frequency modes, whose growth rate increases with the Görtler number. A new varicose even mode is reported, which may promote transition to turbulence at the stem of nonlinear streaks.
In this study, a novel kinematic modeling method of parallel mechanism is proposed. It can obtain position and posture space simultaneously in a single model. Compared with the traditional method only based on inverse kinematics, the novel method can significantly improve computational performance. The original evaluation metric $\mathfrak{R}$ is proposed to evaluate the performance of the two modeling methods. Three groups of experiments with different calculation times are carried out for the classical PPU-3RUS parallel mechanism, and the new RS-3UPRU parallel mechanism after the effectiveness and wide applicability of the novel modeling method is proved. The calculation time and output rate are recorded, respectively, and then the respective $\mathfrak{R}$ values are obtained by weighting. The results show that the novel modeling method has better performance.
Abrupt cessation of heavy cannabis use can cause a withdrawal syndrome characterised by irritability, anxiety, insomnia, reduced appetite and restlessness. Recent reports have also described people in whom cannabis withdrawal immediately preceded the acute onset of psychosis.
Aims
To identify cases of psychosis associated with cannabis withdrawal.
Method
We completed a systematic review of the literature, which comprised case reports, case series and other studies. We also searched a large electronic database of psychiatric healthcare records.
Results
The systematic review identified 44 individuals from 21 studies in whom cannabis withdrawal preceded the development of acute psychosis. In the health record study, we identified another 68 people, of whom 47 involved a first episode of psychosis and 21 represented further episodes of an existing psychotic disorder. Almost all people were daily cannabis users who had stopped using cannabis abruptly. Individuals who continued to use cannabis after the acute psychotic episode had a much higher risk of subsequent relapse than those who abstained (odds ratio 13.9 [95% CI: 4.1 to 56.9]; χ2 = 20.1, P < 0.00001).
Conclusions
Abrupt cannabis withdrawal may act as a trigger for the first episode of psychosis and a relapse of an existing psychosis. Acute psychotic symptoms can emerge after the cessation, as well as following the use, of cannabis.
Carbapenem-resistant Enterobacterales (CRE) are an urgent threat to healthcare, but the epidemiology of these antimicrobial-resistant organisms may be evolving in some settings since the COVID-19 pandemic. An updated analysis of hospital-acquired CRE (HA-CRE) incidence in community hospitals is needed.
Methods:
We retrospectively analyzed data on HA-CRE cases and antimicrobial utilization (AU) from two community hospital networks, the Duke Infection Control Outreach Network (DICON) and the Duke Antimicrobial Stewardship Outreach Network (DASON) from January 2013 to June 2023. The zero-inflated negative binomial regression model was used owing to excess zeros.
Results:
126 HA-CRE cases from 36 hospitals were included in the longitudinal analysis. The pooled incidence of HA CRE was 0.69 per 100,000 patient days (95% confidence interval [95% CI], 0.57–0.82 HA-CRE rate significantly decreased over time before COVID-19 (rate ratio [RR], 0.94 [95% CI, 0.89–0.99]; p = 0.02), but there was a significant slope change indicating a trend increase in HA-CRE after COVID-19 (RR, 1.32 [95% CI, 1.06–1.66]; p = 0.01). In 21 hospitals participating in both DICON and DASON from January 2018 to June 2023, there was a correlation between HA-CRE rates and AU for CRE treatment (Spearman’s coefficient = 0.176; p < 0.01). Anti-CRE AU did not change over time, and there was no level or slope change after COVID.
Conclusions:
The incidence of HA-CRE decreased before COVID-19 in a network of community hospitals in the southeastern United States, but this trend was disrupted by the COVID-19 pandemic.
We consider Markov processes that alternate continuous motions and jumps in a general locally compact Polish space. Starting from a mechanistic construction, a first contribution of this article is to provide conditions on the dynamics so that the associated transition kernel forms a Feller semigroup, and to deduce the corresponding infinitesimal generator. As a second contribution, we investigate the ergodic properties in the special case where the jumps consist of births and deaths, a situation observed in several applications including epidemiology, ecology, and microbiology. Based on a coupling argument, we obtain conditions for convergence to a stationary measure with a geometric rate of convergence. Throughout the article, we illustrate our results using general examples of systems of interacting particles in $\mathbb{R}^d$ with births and deaths. We show that in some cases the stationary measure can be made explicit and corresponds to a Gibbs measure on a compact subset of $\mathbb{R}^d$. Our examples include in particular Gibbs measures associated to repulsive Lennard-Jones potentials and to Riesz potentials.
The coherent vortical structures in turbulent flow through a strong 16 : 1 three-dimensional contraction are studied using time-resolved volumetric measurements. Visualization using the vorticity magnitude criterion shows the emergence of long, stretched cylindrical vortices aligned with the mean flow. This alignment is quantified by probability density functions (p.d.f.s) of the direction cosines. We propose two measures to quantify the alignment, the peak height in the probability and a coefficient from the moment of the p.d.f., both of which reaffirm the strong streamwise alignment. The root mean square streamwise vorticity grows within the contraction to become 4.5 times larger than the transverse component, at the downstream location where the contraction ratio is $C=11$. The characteristic vortices become as long as the measurement volume, or more than 4 times the integral scale at the entrance to the contraction. We also characterize the vorticity enhancement along individual vortices, measuring 65 % strengthening over the distance where $C$ goes from 4 to 11. The prevalence of these coherent structures is estimated from 700 000 measured volumes, showing that near the outlet, it is more likely to have one or two of these structures present than none.
Persistent Betti numbers are a major tool in persistent homology, a subfield of topological data analysis. Many tools in persistent homology rely on the properties of persistent Betti numbers considered as a two-dimensional stochastic process $ (r,s) \mapsto n^{-1/2} (\beta^{r,s}_q ( \mathcal{K}(n^{1/d} \mathcal{X}_n))-\mathbb{E}[\beta^{r,s}_q ( \mathcal{K}( n^{1/d} \mathcal{X}_n))])$. So far, pointwise limit theorems have been established in various settings. In particular, the pointwise asymptotic normality of (persistent) Betti numbers has been established for stationary Poisson processes and binomial processes with constant intensity function in the so-called critical (or thermodynamic) regime; see Yogeshwaran et al. (Prob. Theory Relat. Fields167, 2017) and Hiraoka et al. (Ann. Appl. Prob.28, 2018).
In this contribution, we derive a strong stabilization property (in the spirit of Penrose and Yukich, Ann. Appl. Prob.11, 2001) of persistent Betti numbers, and we generalize the existing results on their asymptotic normality to the multivariate case and to a broader class of underlying Poisson and binomial processes. Most importantly, we show that multivariate asymptotic normality holds for all pairs (r, s), $0\le r\le s<\infty$, and that it is not affected by percolation effects in the underlying random geometric graph.