The concept of agro-sustainability is presented and discussed. The paper shows that sustainable farming practices, sustainable development and the preservation of biological diversity require adequate valorization of local biodiversity. Special emphasis is given to neglected and underutilized crop species. The role and importance of these plants, including primitive wheat, wild anise, food legumes, several vegetables and forage legumes in southern Italy is presented. Each case is presented as an example of cultivation linked to different aspects of utilization, conservation, genetic erosion, and of their potential for sustainable agriculture.

Tree architecture is an important factor in increasing performance and better garden management of pistachios. In a pistachio breeding programme, the genotypes obtained from five open pollinated populations were evaluated in terms of growth characteristics. Among the evaluated genotypes, ‘Apatiye’ was identified. This genotype has shoots with crouch angle more than 90° and a height of 110 cm. In previous year's shoots, the terminal buds abort and fall in early spring, stimulating more lateral buds to grow (6–7) than other genotypes (3–4). The growth characteristics of ‘Apatiye’ create a valuable potential resource for breeding pistachio cultivars with low alternate bearing, suitable for manual harvesting and pruning management. In addition, ‘Apatiye’ can be used as a suitable genetic marker in the study of heritability of growth habit in pistachio trees for future studies.

Rheumatoid arthritis (RA) is a prevalent autoimmune disease, and there is growing evidence suggesting a potential correlation between dietary factors and the pathogenesis of this condition. In order to investigate the causal relationship between diet and RA, we conducted a two-sample Mendelian randomisation (MR) analysis to examine the causal associations between twenty-two dietary factors and RA. Summary data from genome-wide association studies (GWAS) of RA were obtained from large GWAS meta-analyses. GWAS summary data for twenty-two dietary factors were obtained from UK Biobank. Random-effects inverse variance weighted was used as the primary method for assessing causality, and analyses of heterogeneity and horizontal pleiotropy were performed to ensure the accuracy of the results. Research indicates a negative genetic causal relationship between cereal intake (OR = 0·64, 95 % CI: 0·41, 0·99, P = 0·048) and oily fish intake (OR = 0·70, 95 % CI: 0·52, 0·95, P = 0·020) with the risk of RA. Other dietary factors were not causally related to RA. Sensitivity analysis shows that our results are reliable. This study provides genetic evidence suggesting that cereal intake and oily fish intake are protective factors for RA, indicating that RA patients and individuals at high risk should make appropriate dietary adjustments.

We prove the existence of a power structure over the Grothendieck ring of geometric dg categories. We show that a conjecture by Galkin and Shinder (proved recently by Bergh, Gorchinskiy, Larsen and Lunts) relating the motivic and categorical zeta functions of varieties can be reformulated as a compatibility between the motivic and categorical power structures. Using our power structure, we show that the categorical zeta function of a geometric dg category can be expressed as a power with exponent the category itself. We give applications of our results for the generating series associated with Hilbert schemes of points, categorical Adams operations and series with exponent a linear algebraic group.

Brain–computer interfaces (BCIs) exemplify a dual-use neurotechnology with significant potential in both civilian and military contexts. While BCIs hold promise for treating neurological conditions such as spinal cord injuries and amyotrophic lateral sclerosis in the future, military decisionmakers in countries such as the United States and China also see their potential to enhance combat capabilities. Some predict that U.S. Special Operations Forces (SOF) will be early adopters of BCI enhancements. This article argues for a shift in focus: the U.S. Special Operations Command (SOCOM) should pursue translational research of medical BCIs for treating severely injured or ill SOF personnel. After two decades of continuous military engagement and on-going high-risk operations, SOF personnel face unique injury patterns, both physical and psychological, which BCI technology could help address. The article identifies six key medical applications of BCIs that could benefit wounded SOF members and discusses the ethical implications of involving SOF personnel in translational research related to these applications. Ultimately, the article challenges the traditional civilian-military divide in neurotechnology, arguing that by collaborating more closely with military stakeholders, scientists can not only help individuals with medical needs, including servicemembers, but also play a role in shaping the future military applications of BCI technology.

In November 2023, the Department of Health and Social Care published guidance, entitled ‘Baroness Hollins’ Final Report: My Heart Breaks – Solitary Confinement in Hospital Has no Therapeutic Benefit for People with a Learning Disability and Autistic People’. The report's commendable analysis of the problems and identification of the areas where practice should be improved is unfortunately not matched by many of its recommendations, which appear to be contrary to evidence-based approaches. The concerns are wide-ranging, from the use of the term ‘solitary confinement’ for current long-term segregation (LTS) and seclusion, to presumption that all LTS and seclusion is bad, to holding clinicians (mainly psychiatrists) responsible for events beyond their locus of control. Importantly, there is a no guidance on how to practically deliver the recommendations in an evidence-based manner. This Feature critically appraises the report, to provide a comprehensive summary outlining potential positive impacts, identifying specific concerns and reflecting on best practice going forward.

We present the case of 53-year-old woman with a late diagnosis of an right pulmonary artery-left atrium fistula who underwent transcatheter device closure using multi-modality imaging for pre-procedural planning and procedural guidance.

A 17-year-old woman was admitted due to a complete atrioventricular block. Comprehensive analytic and imaging studies were conducted to determine the aetiology. Cardiac magnetic ressonance imaging revealed concentric hypertrophy of the left ventricle and diffuse intramural late enhancement gadolinium. Genetic testing identified a heterozygous pathogenic variant in the desmin gene. To manage atrioventricular block, a dual-chamber pacemaker was implanted. During follow-up, no spontaneous ventricular activity was detected.

While health inequalities among older people have long been a research focus and are now high on policy agendas in developed societies, they have often been neglected in less developed ones, despite them experiencing rapid population ageing since the turn of the century. Using data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) cohort study (N = 63,578), this paper measures the health status of older people using the Quality of Well-Being scale, and estimates time trends in health inequality with concentration indices, followed by an investigation of their social determinants. Its specific focus is health care accessibility (HA) in the period 2005–2018, when China experienced an unprecedented advance in health-related social policy reform. The analysis reveals pro-rich inequalities in health among older people, but also shows that these have narrowed gradually over the past two decades, which is largely attributable to greater equity in access to health care. Within this general trend of inequality reduction, however, the role of HA has declined and social determinants such as education now have an increasing influence on health inequalities. These findings suggest that social policies targeting not only health improvements among older people but also health inequalities earlier in the life course are required if policy makers want to promote health equity in later life.

This paper proposes a nonparametric approach to identify and estimate the generalized additive model with a flexible additive structure and with possibly discrete variables when the link function is unknown. Our approach allows for a flexible additive structure which provides applied researchers the flexibility to specify their model according to economic theory or practical experience. Motivated by the concerns from empirical research, our method also allows for multiple discrete variables in the covariates. By transforming our model into a generalized additive model with univariate component functions, our identification and estimation thereby follows a procedure adapted from the case with univariate components. The estimators converge to normal distributions in large sample with a one-dimensional convergence rate for the link function and a $d_k$-dimensional convergence rate for the component function $f_k(\cdot )$ defined on ${\mathbb R}^{d_k}$ for all k.

This study investigates the linkages between changes in agricultural land use and population growth in India. We have employed long-term time series and a panel dataset of 1869 samples (267 districts × 7 time points from 1961 to 2021) to determine this. We theorize that there is an inverted “U-shape” relationship between changes in population growth and agricultural land. Our findings suggest a positive impact of population growth on the change in cultivated land. However, this relationship was not static during 1961–2021. We found a two-stage split relationship with a breakpoint in 1981. Prior to the 1980s, there was a 12% expansion in cultivated land in response to a unit increase in population growth. During the post-1980s, with a unit decline in population growth, there was a 5% reduction in cultivated land. The findings were reaffirmed through several robustness checks: analyses using alternative outcome variables, alternative break points in a segmented regression model, and spatial modeling. From a policy perspective, this study advances the need for the reduction of population growth rate in high-fertility states and the adoption of superior and green technology for agricultural intensification and diversification to stop cropland expansion at the cost of environmental sustainability.

Music entrepreneurs are by nature intrinsically involved in the music industry due to lifestyle and business reasons. This study investigates the use of lifestyle entrepreneurship behaviours by taking a gender perspective about how music entrepreneurs develop commercial activities. This includes focusing on how international relationships relate to meaningful music entrepreneurial experience based on the use of social capital. Drawing on interview data from 12 female music entrepreneurs the findings highlight lifestyle identification responses to entrepreneurship as central constituents. Moreover, the study shows how female music entrepreneurs tap into their lifestyle connections based on their gender and social interests. The article contributes to the development of the music, gender, lifestyle, and digital entrepreneurship work by identifying a more interdisciplinary perspective. The practical implications for the music industry evolve around helping more female entrepreneurs break into the sector by harnessing their creative potential.

There is scientific consensus that an earthquake of a magnitude of at least 7 will soon occur on the North Anatolian Fault, which runs south of İstanbul. This earthquake would render one-fifth of İstanbul’s buildings uninhabitable, which means that approximately 200,000 buildings would be expected to suffer moderate or severe damage. As a part of preparedness for the anticipated earthquake, people in İstanbul are invited to have their buildings risk tested. This article, pivoting on cultural anthropology and science and technology studies, investigates how earthquake-proneness of buildings in İstanbul is technically and legally examined and determined. It ethnographically analyzes the risk assessments and demonstrates that the risk is enacted differently through distinctive engineering practices and legal regulations in different networks. When the two different risk assessment processes are examined in İstanbul, a building that is categorized as risky due to its earthquake vulnerability could be regarded as sturdy in the other assessment.

Depression is transmitted within families, but the mechanisms involved in such transmission are not clearly defined. A potential marker of familial risk is the neural response to errors, which may play a role in depression symptoms and is known to be partially heritable. Here, 97 mother-daughter dyads completed a Flanker task while electroencephalography markers of error monitoring were recorded: the error-related negativity (ERN) and response-locked delta and theta power. We assessed whether these measures of neural response to errors 1) were associated with history of recurrent major depressive disorder (MDD) and current depression symptoms among mothers, 2) were correlated among mother-daughter dyads, and 3) were associated with maternal history of recurrent MDD and maternal symptoms of depression among daughters. A history of recurrent MDD was associated with blunted delta and increased theta among mothers. Across mothers, delta and theta were negatively and positively associated, respectively, with current depression symptoms. Mothers’ and daughters’ ERN were positively correlated. Finally, current maternal depression symptoms were negatively associated with delta power in daughters. These results suggest that neural responses to errors may be implicated in the intergenerational transmission of depression. These results also support the relevance of delta oscillations to understanding pathways to depression.