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The reprocessing of personal protective equipment that is only intended for single use has been brought into focus by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, especially regarding respiratory masks.1–4
Turbulent flows in three dimensions are characterized by the transport of energy from large to small scales through the energy cascade. Since the small scales are the result of the nonlinear dynamics across the scales, they are often thought of as universal and independent of the large scales. However, as famously remarked by Landau, sufficiently slow variations of the large scales should nonetheless be expected to impact small-scale statistics. Such variations, often termed large-scale intermittency, are pervasive in experiments and even in simulations, while differing from flow to flow. Here, we evaluate the impact of temporal large-scale fluctuations on velocity, vorticity and acceleration statistics by introducing controlled sinusoidal variations of the energy injection rate into direct numerical simulations of turbulence. We find that slow variations can have a strong impact on flow statistics, raising the flatness of the considered quantities. We discern three contributions to the increased flatness, which we model by superpositions of statistically stationary flows. Overall, our work demonstrates how large-scale intermittency needs to be taken into account in order to ensure comparability of statistical results in turbulence.
Cardiac surgery-associated acute kidney injury (CS-AKI) and fluid overload (FO) are common among neonates who undergo cardiopulmonary bypass, and increase mortality risk. Current diagnostic criteria may delay diagnosis. Thus, there is a need to identify urine biomarkers that permit earlier and more accurate diagnosis.
Methods:
This single-centre ancillary prospective cohort study describes age- and disease-specific ranges of 14 urine biomarkers at perioperative time points and explores associations with CS-AKI and FO. Neonates (≤28 days) undergoing cardiac surgery were included. Preterm neonates or those who had pre-operative acute kidney injury were excluded. Urine biomarkers were measured pre-operatively, at 0 to < 8 hours after surgery, and at 8 to 24 hours after surgery. Exploratory outcomes included CS-AKI, defined by the modified Kidney Disease Improving Global Outcomes criteria, and>10% FO, both measured at 48 hours after surgery.
Results:
Overall, α-glutathione S-transferase, β-2 microglobulin, albumin, cystatin C, neutrophil gelatinase-associated lipocalin, osteopontin, uromodulin, clusterin, and vascular endothelial growth factor concentrations peaked in the early post-operative period; over the sampling period, kidney injury molecule-1 increased and trefoil factor-3 decreased. In the early post-operative period, β-2 microglobulin and α-glutathione S-transferase were higher in neonates who developed CS-AKI; and clusterin, cystatin C, neutrophil gelatinase-associated lipocalin, osteopontin, and α-glutathione S-transferase were higher in neonates who developed FO.
Conclusion:
In a small, single-centre cohort, age- and disease-specific urine biomarker concentrations are described. These data identify typical trends and will inform future studies.
Les élections municipales de 2021 à la Ville de Québec ont été marquées par une forte compétition entre cinq candidats et une saillance des enjeux concernant la construction d'un tramway et d'un troisième lien autoroutier entre Québec et sa Rive-Sud. Ainsi, cette élection représente un contexte idéal pour étudier le comportement électoral au niveau local et plus spécifiquement le vote sur enjeu qui a été très peu étudié dans le contexte municipal. Nous soutenons que ces deux enjeux ont acquis une valeur symbolique et ont été exploités comme enjeu de brèche par le candidat à la mairie Jean-François Gosselin. À l'aide d'une analyse multivariée, nous testons la relation entre l'appui aux deux projets de transport et l'intention de vote. Nos résultats montrent que les attitudes des électeurs envers ces deux enjeux sont fortement corrélées avec leur choix de vote et suggèrent une continuité entre le comportement électoral municipal, provincial et fédéral, du moins lorsqu'il est question de vote sur les enjeux.
Established studies show that after the fall of the capital-based elites during the end of the Tang dynasty, the Northern Song literati became active in serving the central government. However, after the century-long Interregnum (878–978), during which literati from the South remained beyond the rule of the Central Plains dynasties, how did they establish a cooperative relationship with the emerging Song court? Taking Puyang in Fujian as an example, this article analyzes the writings of Puyang literati to illustrate how their narratives shaped political relationships between the center and periphery. It demonstrates how literati responded variously to specific political contexts, sometimes showcasing their own local identity and at other times extolling the rule of the Central Plains. The case of Puyang reveals that the challenging political environment of the Interregnum actually stimulated and accelerated cooperation between the Central Plains and the local literati through civil service examinations.
To evaluate the perception of disaster preparedness and response self-efficacy of nurses living and working in the region affected by the earthquakes in Turkey on February 6, 2023.
Methods
This cross-sectional, relationship-seeking research was conducted between March 10 and May 10, 2024 with 344 nurses in a hospital in the province of Kahramanmaraş, which was the epicentre of the February 2023 earthquake. A Personal Information Form, the Perception of Nurses of Disaster Preparedness Scale (PNDPS), and the Disaster Response Self-Efficacy Scale (DRSES) were used in data collection. Pathway analysis and confirmatory factor analyis were used in the evaluation of the data.
Results
Age, gender, educational level, disaster training, and having lost someone close in a disaster were determined to have a significant effect on the perception of disaster preparedness, and response self-efficacy (P < 0.05). The perception of the stage of preparation was determined to be 0.136-fold greater in those with a disaster preparation plan (P < 0.05). Perception of the post-disaster stage was determined to be 0.130-fold greaater in those with a disaster preparation plan (P < 0.05).
Conclusions
This study demonstrated that nurses working in the earthquake region had high levels of disaster preparedness perception and response self-efficacy.
This article focuses on the early history of Northwestern European opinion polling (1940s–1950s), specifically the cases of the Netherlands and Sweden. The evolution of opinion polling and its influence on post-war politics and society should be understood in light of processes of international transfer and entanglement. The Dutch-Swedish comparison brings into focus the ways in which the national experiences of the Second World War influenced how opinion pollsters discursively linked the practice to ideas about democracy. Furthermore, the article highlights entanglements across the boundaries of science, as commercial survey methods were picked up by social scientists, and across national borders, as opinion pollsters across Western Europe were in frequent contact with each other.
The interaction between planar incident shocks and cylindrical boundary layers is prevalent in missiles equipped with inverted inlets, which typically leads to substantial three-dimensional flow separation and the formation of vortical flow. This study utilizes wind-tunnel experiments and theoretical analysis to elucidate the shock structure, surface topology and pressure distributions induced by a planar shock with finite width impinging on a cylinder wall at Mach 2.0. In the central region, a refraction phenomenon occurs as the transmitted shock bends within the boundary layer, generating a series of compression waves that coalesce into a shock, forming a ‘shock triangle’ structure. As the incident shock propagates backward along both sides, it gradually evolves into a Mach stem, where the transmitted shock refracts the expansion wave. The incident shock interacts with the boundary layer, resulting in the formation of a highly swept separation region that yields a pair of counter-rotating horseshoe-like vortices above the separation lines. These vortices facilitate the accumulation of low-energy fluid on both sides. Although the interaction of the symmetry plane aligns with free-interaction-theory, the separation shock angle away from the centre significantly deviates from the predicted value owing to the accumulation of low-energy fluids. The primary separation line and pressure distribution jointly exhibit an elliptical similarity on the cylindrical surface. Furthermore, the potential unsteady behaviour is assessed, and the Strouhal number of the low-frequency oscillation is found to be 0.0094, which is insufficient to trigger significant alterations in the flow field structure.
At the entrance to this impressive exhibition stands Umberto Boccioni's dramatic bronze sculpture, Forms of Continuity in Space (1913), a Futurist piece filled with power, movement and innovation. It is a fitting introduction to what follows.
The Commission for Relief in Belgium (CRB), established in October 1914 and overseen throughout the war by Herbert Hoover, played a pivotal role in saving millions of Belgians and hundreds of thousands of French from starvation. The proposed article aims to address this gap by examining the phenomenon of an ambivalent, even asymmetrical, diplomacy of gratitude. Herbert Hoover and his Belgian counterpart (and humanitarian rival), the financier Emile Francqui, had initially devised a strategy of remembrance of their wartime collective action, which centred on children, youth and higher education. Nevertheless, while their endeavour to establish a unified Belgian-American foundation ultimately failed due to their diverging postwar agendas, the dominant narrative of US aid encountered mounting opposition within Belgian political and academic circles. In the context of competing national memories and shifting feelings of gratitude, American philanthropy played a seminal role in the co-construction of modern higher education infrastructures in Belgium.
Primary hyperparathyroidism (PHPT) is the presence of hypercalcaemia with an elevated or inappropriately normal parathyroid hormone level. In clinical psychiatry this is often detected on routine blood investigations. This article aims to help mental health professionals understand the relevance of PHPT to psychiatry and offers some guidance about further management of patients presenting with this endocrine abnormality in mental health settings. PHPT can be associated with both mental and physical health problems in some individuals, making it a crucial diagnosis that should not be overlooked.
The genetic diversity of Cyclanthera pedata was assessed through agro-morphological, mineral composition and biochemical traits. Field surveys across India documented its wide ecological distribution (18.66°–31.02°N, 78.05°–83.27°E, 131–3665 m AMSL) in Andhra Pradesh and northwest Himalayan region. Field evaluations were conducted during Kharif 2021 and 2022 at ICAR-Vivekananda Parvatiya Krishi Anusandhan Sansthan, Almora (1250 m AMSL). Significant genotypic variation was observed in fruit yield (195–1505 g/plant), fruit numbers (36–364 per plant), chlorophyll content (0.49–2.61 μg/g) and antioxidant activities (16.02–39.04 mM Trolox equivalent/g DW). Notable genotypes included RK-40 (highest yield of 1505 g/plant), RK-01 (early flowering) and RK-33 (early fruiting). High coefficients of variation (>23%) were noted in total chlorophyll, carotenoids and FRAP values. Genotype RK-42 excelled in antioxidant activities and carotenoids. Hierarchical cluster analysis grouped the germplasm into four clusters based on critical traits independent of geographic origin. In contrast, principal component analysis identified traits like polyphenols, antioxidants, seed weight and fruit yield as significant contributors to phenotypic variation. The biplot revealed relationships between traits, such as positive correlations between fruit yield, fruit and pulp weight, and biochemical traits like DPPH and ABTS. Genotypes such as IC 430006, IC 356007, IC 393261, IC 393308, UKAl 1 and IC 361297 display distinct profiles. These findings highlight critical traits for breeding and conservation efforts, particularly for enhancing fruit yield and biochemical attributes in C. pedata germplasm.
Given a full right-Hilbert $\mathrm {C}^{*}$-module $\mathbf {X}$ over a $\mathrm {C}^{*}$-algebra A, the set $\mathbb {K}_{A}(\mathbf {X})$ of A-compact operators on $\mathbf {X}$ is the (up to isomorphism) unique $\mathrm {C}^{*}$-algebra that is strongly Morita equivalent to the coefficient algebra A via $\mathbf {X}$. As a bimodule, $\mathbb {K}_{A}(\mathbf {X})$ can also be thought of as the balanced tensor product $\mathbf {X}\otimes _{A} \mathbf {X}^{\mathrm {op}}$, and so the latter naturally becomes a $\mathrm {C}^{*}$-algebra. We generalize both of these facts to the world of Fell bundles over groupoids: Suppose $\mathscr {B}$ is a Fell bundle over a groupoid $\mathcal {H}$ and $\mathscr {M}$ is an upper semi-continuous Banach bundle over a principal $\mathcal {H}$-space X. If $\mathscr {M}$ carries a right-action of $\mathscr {B}$ and a sufficiently nice $\mathscr {B}$-valued inner product, then its imprimitivity Fell bundle$\mathbb {K}_{\mathscr {B}}(\mathscr {M})=\mathscr {M}\otimes _{\mathscr {B}} \mathscr {M}^{\mathrm {op}}$ is a Fell bundle over the imprimitivity groupoid of X, and it is the unique Fell bundle that is equivalent to $\mathscr {B}$ via $\mathscr {M}$. We show that $\mathbb {K}_{\mathscr {B}}(\mathscr {M})$ generalizes the “higher order” compact operators of Abadie–Ferraro in the case of saturated bundles over groups, and that the theorem recovers results such as Kumjian’s Stabilization trick.
Bob Morris was elected as president of the European Association for Urban History (EAUH) ahead of its 2002 conference in Edinburgh. Bob’s presidency, and the Edinburgh conference specifically, took place at an important point in the development of urban history within Europe and further afield. First, the programme reveals several emerging themes and topics of interest that have since shaped the sub-field in new and innovative ways. Second, Bob’s informal and collegial approach towards networking is reflected in the decision to place the EAUH on a quasi-formal constitutional basis. Both of these developments reflect, in part, Bob’s own research interests, as well as the sub-field’s welcoming approach to younger researchers, including taught and research postgraduate students, interested in networking with more established scholars.
While malnutrition (including both undernutrition and overweight/obesity and related non-communicable diseases) remains a persistent challenge in countries around the world, it is far from alone as a threat to human development and wellbeing – and is increasingly viewed as intersecting with climate change and environmental degradation. At the crossroads of these issues, animal-source foods (ASFs, including meat, fish, seafood, dairy and eggs) have attracted considerable attention in recent years, both for their role in diets and for their environmental impacts. Heated debate has focused on the potential benefits of reducing consumption of ASFs as well as the potential nutritional risks associated with this. ASF production also plays an important role in livelihoods, particularly in low- and middle-income countries. ASFs are also central to many food cultures and traditions, highly valued by many consumers. As the issues associated with ASFs are intertwined, they must be considered jointly and with nuance. Given wide global ranges in ASF consumption, environmental footprints and malnutrition rates and types, considering equity (in terms of ASF consumption and production) is also critical. This review examines these complex issues, discussing ASFs from the perspectives of nutrition and health, environmental impacts, livelihoods and society, and equity. It also examines potential future options for reducing environmental impacts of ASFs.
Hegel is a complicated figure for considering the philosophical significance of sexual difference. On the one hand, he grants an essential place for sexual difference in his analyses of nature and spirit. On the other hand, he treats the telos of sexual difference as a kind of sexual indifferentiation. For Hegel, both life and spirit depend on sexual difference but as something to be sublated, that is, preserved but only in so far as it is negated for a higher truth or purpose devoid of it. This essay examines this sublation of sexual difference in what Hegel characterizes as the ‘universality’ of the living genus and the ‘universality’ of the rational activity of civil society. I argue that Hegel’s conception of this sublation of difference into universality relies in both instances on a teleological reduction of the ontological significance of sexual difference to reproduction and a contestable interpretation of the roles of male and female sexes in it. However, I claim that Hegel’s account of the relational identity of the sexes, each as not-all of the genus given the other, is a fundamental insight for an ontological analysis of sexual difference. As such, I open a critical reappropriation of Hegel's account of sexual difference for a more difference-affirming, non-hierarchal sexual ontology. I argue that overcoming the hierarchal implications of this Hegelian account of sexual difference requires rethinking the natural and rational universal, which amounts to rethinking what Hegelianism might mean today.