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The role of initial specimen diversion devices (ISDDs) in preventing contamination of central venous catheter (CVC) blood cultures is undefined. A model to simulate CVC colonization and contamination compared standard cultures with ISDD technique. ISDD detected 100% of colonized CVCs while decreasing false-positive cultures from 36% to 16%.
Organizations are utilizing digital technologies to modernize their innovations in today’s competitive and rapidly changing market environment. This study’s goal is to explore the influence of open innovation on firms’ digital technology integration, aiming to enhance their innovation skills and produce competitive, adaptable digital solutions. The methods used include analysis, synthesis, and generalization. Organizations can enhance open innovation by acquiring knowledge, capabilities, ideas, technologies, and information for new products and services, with the relationship between open innovation and digital innovation accelerating their capabilities. The study emphasizes the challenges organizations face in modern IT, emphasizing open innovation, access to external knowledge, and the need for improved internal production efficiency and competitiveness. The practical value of this study is manifested in the identification of strategies for optimizing open innovation for their transformation into digital solutions.
The lubricated motion of an object near a deformable boundary presents striking subtleties arising from the coupling between the elasticity of the boundary and lubricated flow, including but not limited to the emergence of a lift force acting on the object despite the zero Reynolds number. In this study, we characterize the hydrodynamic forces and torques felt by a sphere translating in close proximity to a fluid interface, separating the viscous medium of the sphere's motion from an infinitely more viscous medium. We employ lubrication theory and perform a perturbation analysis in capillary compliance. The dominant response of the interface owing to surface tension results in a long-ranged interface deformation, which leads to a modification of the forces and torques with respect to the rigid reference case, that we characterize in detail with scaling arguments and numerical integrations.
This paper derives the upper bound on heat transport in supergravitational turbulent thermal convection analytically and numerically. Using a piecewise background profile, the functional inequality analysis delivers a suboptimal bound $Nu\lesssim -({3\sqrt {3}}/{2})({\eta \ln (\eta )}/({1-\eta ^2}))\,Ra^{1/2}$ as $Ra\rightarrow \infty$, where $Nu$ is the Nusselt number, $\eta$ is the radius ratio of the inner cylinder to the outer cylinder ($0<\eta <1$), and $Ra$ is the Rayleigh number. A variational problem yielded from Doering–Constantin–Hopf formalism is solved asymptotically and numerically, which delivers a better upper bound than the piecewise background profile. The asymptotic analysis and numerical data indicate that the current best bound is given by $Nu\leqslant -0.106({\eta \ln (\eta )}/({(1-\eta )(1+\sqrt {\eta })^2}))\,Ra^{1/2}$. Both analytical and numerical results demonstrate that the upper bound can be significantly reduced by the curvature effect. Unlike the traditional Rayleigh–Bénard turbulence, in which the optimal perturbation yielded from the variational problem is always two-dimensional, the present study shows that three-dimensional perturbations, annular perturbations and axisymmetric perturbations can be induced by the curvature effect simultaneously. However, we show that the bound yielded from the three-dimensional variational problem is very close to the axisymmetric situation as $\eta$ increases and $Ra$ increases.
Evidence-based insertion and maintenance bundles are effective in reducing the incidence of central line-associated bloodstream infections (CLABSI) in intensive care unit (ICU) settings. We studied the adoption and compliance of CLABSI prevention bundle programs and CLABSI rates in ICUs in a large network of acute care hospitals across Canada.
Surface roughness significantly modifies the liquid film thickness entrained when dip coating a solid surface, particularly at low coating velocity. Using a homogenization approach, we present a predictive model for determining the liquid film thickness coated on a rough plate. A homogenized boundary condition at an equivalent flat surface is used to model the rough boundary, accounting for both flow through the rough texture layer, through an interface permeability term, and slip at the equivalent surface. While the slip term accounts for tangential velocity induced by viscous shear stress, accurately predicting the film thickness requires the interface permeability term to account for additional tangential flow driven by pressure gradients along the interface. We find that a greater degree of slip and interface permeability signifies less viscous stress that would promote deposition, thus reducing the amount of free film coated above the textures. The model is found to be in good agreement with experimental measurements, and requires no fitting parameters. Furthermore, our model may be applied to arbitrary periodic roughness patterns, opening the door to flexible characterization of surfaces found in natural and industrial coating processes.
Let $H\le F$ be two finitely generated free groups. Given $g\in F$, we study the ideal $\mathfrak I_g$ of equations for g with coefficients in H, i.e. the elements $w(x)\in H*\langle x\rangle$ such that $w(g)=1$ in F. The ideal $\mathfrak I_g$ is a normal subgroup of $H*\langle x\rangle$, and it’s possible to algorithmically compute a finite normal generating set for $\mathfrak I_g$; we give a description of one such algorithm, based on Stallings folding operations. We provide an algorithm to find an equation in w(x)\in$\mathfrak I_g$ with minimum degree, i.e. such that its cyclic reduction contains the minimum possible number of occurrences of x and x−1; this answers a question of A. Rosenmann and E. Ventura. More generally, we show how to algorithmically compute the set Dg of all integers d such that $\mathfrak I_g$ contains equations of degree d; we show that Dg coincides, up to a finite set, with either $\mathbb N$ or $2\mathbb N$. Finally, we provide examples to illustrate the techniques introduced in this paper. We discuss the case where ${\text{rank}}(H)=1$. We prove that both kinds of sets Dg can actually occur. We show that the equations of minimum possible degree aren’t in general enough to generate the whole ideal $\mathfrak I_g$ as a normal subgroup.
This paper proposes an online robust self-learning terminal sliding mode control (RS-TSMC) with stability guarantee for balancing control of reaction wheel bicycle robots (RWBR) under model uncertainties and disturbances, which improves the balancing control performance of RWBR by optimising the constrained output of TSMC. The TSMC is designed for a second-order mathematical model of RWBR. Then robust adaptive dynamic programming based on an actor-critic algorithm is used to optimise the TSMC only by data sampled online. The system closed-loop stability and convergence of the neural network weights are guaranteed based on the Lyapunov analysis. The effectiveness of the proposed algorithm is demonstrated through simulations and experiments.
Hydrodynamic interactions between swimming or flying organisms can lead to complex flows on the scale of the group. These emergent fluid dynamics are often more complex than a linear superposition of individual organism flows, especially at intermediate Reynolds numbers. This paper presents an approach to estimate the flow induced by multiple swimmer wakes in proximity using a semianalytical model that conserves mass and momentum in the aggregation. The key equations are derived analytically, while the implementation and solution of these equations are carried out numerically. This model was informed by and compared with empirical measurements of induced vertical migrations of brine shrimp, Artemia salina. The response of individual swimmers to ambient background flow and light intensity was evaluated. In addition, the time-resolved three-dimensional spatial configuration of the swimmers was measured using a recently developed laser scanning system. Numerical results using the model found that the induced flow at the front of the aggregation was insensitive to the presence of downstream swimmers, with the induced flow tending towards asymptotic beyond a threshold aggregation length. Closer swimmer spacing led to higher induced flow speeds, in some cases leading to model predictions of induced flow exceeding swimmer speeds required to maintain a stable spatial configuration. This result was reconciled by comparing two different models for the near-wake of each swimmer. The results demonstrate that aggregation-scale flows result from a complex, yet predictable interplay between individual organism wake structure and aggregation configuration and size.
Mounting evidence suggests that the Mediterranean diet has a beneficial effect on mental health. It has been hypothesised that this effect is mediated by a variety of foods, nutrients and constituents; however, there is a need for research elucidating which of these components contribute to the therapeutic effect. This scoping review sought to systematically search for and synthesise the research on olive oil and its constituents and their impact on mental health, including the presence or absence of a mental illness or the severity or progression of symptoms. PubMed and OVID MEDLINE databases were searched. The following article types were eligible for inclusion: human experimental and observational studies, animal and preclinical studies. Abstracts were screened in duplicate, and data were extracted using a piloted template. Data were analysed qualitatively to assess trends and gaps for further study. The PubMed and OVID MEDLINE search yielded 544 and 152 results, respectively. After full-text screening, forty-nine studies were eligible for inclusion, including seventeen human experimental, eighteen observational and fourteen animal studies. Of these, thirteen human and four animal studies used olive oil as a comparator. Observational studies reported inconsistent results, specifically five reporting higher rates of mental illness, eight reporting lower and five reporting no association with higher olive oil intake. All human experimental studies and nine of ten animal studies that assess olive oil as an intervention reported an improvement of anxiety or depression symptoms. Olive oil may benefit mental health outcomes. However, more experimental research is needed.
We show that when a finitely presented Bestvina–Brady group splits as an amalgamated product over a subgroup $H$, its defining graph contains an induced separating subgraph whose associated Bestvina–Brady group is contained in a conjugate of $H$.
When they occur, azimuthal thermoacoustic oscillations can detrimentally affect the safe operation of gas turbines and aeroengines. We develop a real-time digital twin of azimuthal thermoacoustics of a hydrogen-based annular combustor. The digital twin seamlessly combines two sources of information about the system: (i) a physics-based low-order model; and (ii) raw and sparse experimental data from microphones, which contain both aleatoric noise and turbulent fluctuations. First, we derive a low-order thermoacoustic model for azimuthal instabilities, which is deterministic. Second, we propose a real-time data assimilation framework to infer the acoustic pressure, the physical parameters, and the model bias and measurement shift simultaneously. This is the bias-regularized ensemble Kalman filter, for which we find an analytical solution that solves the optimization problem. Third, we propose a reservoir computer, which infers both the model bias and measurement shift to close the assimilation equations. Fourth, we propose a real-time digital twin of the azimuthal thermoacoustic dynamics of a laboratory hydrogen-based annular combustor for a variety of equivalence ratios. We find that the real-time digital twin (i) autonomously predicts azimuthal dynamics, in contrast to bias-unregularized methods; (ii) uncovers the physical acoustic pressure from the raw data, i.e. it acts as a physics-based filter; (iii) is a time-varying parameter system, which generalizes existing models that have constant parameters, and capture only slow-varying variables. The digital twin generalizes to all equivalence ratios, which bridges the gap of existing models. This work opens new opportunities for real-time digital twinning of multi-physics problems.
Constrictive pericarditis is a rare complication after cardiac surgery. It is mostly seen in adults. We report a case of constrictive pericarditis in a 3-year-old child with right ventricular dysfunction after permanent pacemaker implantation during infancy for congenital complete heart block. Suspicion of constrictive pericarditis must be kept in mind during evaluation.
Canada is regarded as an early adopter of democratic innovations, including the high-profile BC Citizens’ Assembly on Electoral Reform. To what extent has Canada maintained this trajectory? We examine this in the context of breadth and depth by examining trends in adoption over time across Canada and case-level adoption according to the dimensions of influence and temporality. While case studies of Canadian democratic innovations exist, these do not provide analytical capacity to understand trends in the breadth of adoption; we thus contribute a novel dataset of democratic innovations in Canada from 2000 to 2020. To analyze the depth of adoption, we present a two-by-three framework, which we apply to interpret our dataset of Canadian democratic innovations. We find that while there is an increase in the total number of democratic innovations, a low quantity is observed that exhibits high influence and permanence.
This paper studies the heterogeneity of households’ present bias in a heterogeneous-agent model. Our model jointly matches the average marginal propensities to consume and the wealth distribution in the USA, even when all wealth is liquid. A fiscal stimulus targeting households in the bottom half of the wealth distribution improves the consumption response. A financial literacy campaign removing present bias gets naive households out of the debt trap but harms sophisticated households’ wealth accumulation due to a lower equilibrium interest rate. Finally, we show that a borrowing cost penalty and illiquidity both discipline excessive borrowing and are therefore potential remedies for present bias and naivete.