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How do residents evaluate zoning relief applications for new houses of worship? Do they decide based on the facility’s expected level of nuisance, the religion of the house of worship, or the attitudes of neighbors and local officials? Using a conjoint survey experiment, this paper shows that religion is the most important predictor of resistance. People are more likely to resist new mosques than Christian churches, irrespective of other facility properties. Furthermore, this paper highlights the significant role of partisanship in residents’ evaluation of zoning relief applications. Republican respondents were more likely to reject minority houses of worship and support Christian churches than Democrats, moderating the influence of religion. Such bias has important implications for the zoning relief application process. Local officials should evaluate residents’ opposition differently when the application concerns minority groups.
The aim of this review is to summarize the progress made in the determination of the protonation constants of biologically active ligands: endo- and exogenous L-amino acids and their derivatives in aqueous and mixed solutions using different experimental techniques. The knowledge of the protonation constants of the aforementioned ligands is crucial for the determination of the equilibrium constants of complex formation and thus for the understanding of complex biological reactions such as transamination, racemization, and decarboxylation. Thus, the protonation constants of ligands are a measure of their ability to form complexes with metal ions. This knowledge not only helps to understand fundamental biochemical processes, but also has practical applications in areas such as drug design, where ligands are often targeted for therapeutic purposes. The activity of the ligands tends to increase after complexation and their order is consistent with the values of the stepwise dissociation constants of the complexes formed. Understanding the properties of ligands by determining their protonation constants in different environments and their interactions with surrounding molecules is crucial to unraveling the complexity of biological systems.
Drawing on job-demands resources and self-consistency theories, this study investigates individual and contextual factors influencing managers’ intrapreneurial intention (INI). We focus on the role of personal resources (organization-based self-esteem and proactivity) related to INI. Further, we analyze job resources (top management support and role clarity) shaping INI, and their interaction with proactivity. Our data comprises 193 Kosovan managers employed in companies varying in size and industry. The results show that organization-based self-esteem and proactivity are positively related to INI. Additionally, proactivity serves as the underlying mechanism, mediating organization-based self-esteem-INI relationship. Furthermore, job resources – top management support and role clarity – strengthen the likelihood of INI among proactive employees, suggesting a moderated mediation model.
By jointly examining individual and contextual antecedents of INI, this study contributes to the debate of who the intrapreneur is and what nurtures his/her inclinations. Furthermore, this is among the few studies to examine INI using a managerial sample and in an emerging economy context.
The aim of this study is to assess General Practitioner (GP) trainees’ training experience, and confidence in assessing and managing children and adolescents with common mental health conditions in primary care in Ireland.
Methods:
An online anonymous questionnaire was distributed to third and fourth year GP registrars enrolled in the Irish College of General Practitioners training schemes. The online questionnaire evaluated participants’ training experiences and confidence levels in key areas of child and adolescent mental health in primary care.
Results:
Sixty participants completed the survey out of 406, yielding a response rate of 14.8%. The majority (88%) reported no formal training or experience working in Child and Adolescent Mental Healthcare Services (CAMHS) during their GP training scheme. Responses indicated that many participants rated their competency, skills, and knowledge in essential areas of Child and Adolescent Mental Health as needing improvement. Similarly, their awareness of referral pathways and specialty services was below expectations, with poor perceived access to services. A large proportion (91.7%) expressed a definite need for further training in child and adolescent mental health disorders.
Conclusion:
The results highlight the need for enhanced training and support for GP trainees in the field of Child and Adolescent Mental Health, ensuring their ability to effectively and confidently address these common issues in primary care.
The growing focus on the agency of norm violators has led to new insights on various rhetorical strategies that states accused of norm violation deploy. However, few studies have simultaneously examined both specific rhetorical devices that enable norm evasion and their social psychological underpinnings. Building on International Relations (IR) research on norm evasion and social psychological research on in-group wrongdoings, this paper conceptualises states’ rhetoric of norm evasion as a social psychological coping strategy: aimed at protecting in-group esteem. Empirically, the paper offers a systematic analysis of Japan’s rhetoric of norm evasion regarding its colonial and wartime past, as well as its social psychological underpinnings. Five rhetorical strategies of norm evasion are identified: (1) claiming legality, (2) claiming the inapplicability of relevant treaties, (3) claiming the inapplicability of relevant norms, (4) equivocating, and (5) citing non-disparagement pledges. These strategies, as well as the psychological disengagement they enable, have culminated in the promotion of non-remembrance, or behavioural manifestations of norm regress.
The design of motion control systems for legged robots has always been a challenge. This article first proposes a motion control method for legged robots based on the gradient central pattern generator (GD-CPG). The periodic signals output from the GD-CPG neural network are used as the drive signals of each thigh joint of the legged robots, which are then converted into the driving signal of the knee and ankle joints by the thigh–knee mapping function and the knee–ankle mapping function. The proposed control algorithm is adapted to quadruped and hexapod robots. To improve the ability of legged robots to cope with complex terrains, this article further proposes the responsive gradient-CPG motion control method for legged robots. From the perspective of bionics, a biological vestibular sensory feedback mechanism is established in the control system. The mechanism adjusts the robot’s motion state in real time through the attitude angle of the body measured during the robot’s motion, to keep the robot’s body stable when it moves in rugged terrains. Compared with the traditional feedback model that only balances the body pitch, this article also adds the balancing functions of body roll and yaw to balance the legged robot’s motion from more dimensions and improve the linear motion capability. This article also introduces a differential evolutionary algorithm and designs a fitness function to adaptively optimize vestibular sensory feedback parameters. The validity, robustness, and transferability of the method are verified through simulations and physical experiments.
Totalism states that one population is better than another iff it has higher total welfare. One counterintuitive consequence is the Repugnant Conclusion (RC). Totalism also entails that a very large population of animals with lives barely worth living is better than a smaller population of happier humans. Furthermore, the strategies that have been used to avoid the troubling normative implications of the RC do not work in the animal case, so we may have reason to bring about such a population. I introduce the notion of ‘Efficiency of Welfare Production’ – that animals of different species vary in the efficiency with which they convert resources into welfare. If we want to maximize total welfare, without any speciesist bias, we should identify which species is most efficient and try to maximize the population of that species. This has counterintuitive implications whether we accept hedonism or a more sophisticated theory of welfare.
Work stress and employee wellbeing have gained heightened attention since the COVID-19 pandemic. Until now, organizations have primarily sought to conceptualize these variables as an individual-level phenomenon; thereby neglecting the potential influence of social dynamics within the workplace. Drawing on conservation of resources and emotional contagion theories, this study examines the extent to which team-level emotional contagion moderates the impact of stress on wellbeing, factoring in multilevel effects. Data from 237 professional services employees nested within 41 teams was analyzed. The results show support for emotional contagion as a team-level moderator between individual-level work stress and employee wellbeing. The role of organizational resources in shaping stress and wellbeing outcomes was also significant. This study underscores the significance of team dynamics and organizational resources in shaping employee wellbeing. Well-targeted, stress alleviation, and team-contagion enhancing initiatives will have a more positive impact on wellbeing, than individually targeted stress alleviation initiatives in isolation.
A newborn with unbalanced atrioventricular septal defect and heterotaxy syndrome underwent early surgeries for single-ventricular palliation due to a small left ventricle. Following procedures, including the modified Damus–Kaye–Stansel, there was a notable increase in left ventricular size. This progression allowed successful biventricular repair at 7 months. This case highlights potential ventricular development after palliative procedures in patients with borderline ventricular size.
Former refugee women’s entrepreneurial journeys are embedded in social, cultural, and legal environments in their home, transition, and host countries. Their multiple context embeddedness creates contradictions and identity issues. Thus, women adopt behaviours that make them visible or invisible simultaneously when navigating these contradictions. Using intersectionality and translocational positionality lenses, this study explored this phenomenon. We collected narrative data using semi-structured interviews from refugee women resettled in New Zealand. The findings illustrate that multi-country social processes, that is, ‘translocational’ experiences, create (in)visibility paradoxes for women entrepreneurs. Women dynamically create visibility for themselves through reliance on or defiance of ethnic, cultural or refugee identities in their ventures and by creating a business identity aligning with the host country’s values. In contrast, cultural conformity and playing a role behind the ‘shopfront’ make women invisible. This study synthesises these paradoxical entrepreneurial strategies, develops a conceptual framework and contributes to women’s entrepreneurial identity studies.
In studying the transport of inclusions in multiphase systems we are often interested in integrated quantities such as the net force and the net velocity of the inclusions. In the reciprocal theorem the known solution to the first and typically easier boundary value problem is used to compute the integrated quantities, such as the net force, in the second problem without the need to solve that problem. Here, we derive a reciprocal theorem for poro-viscoelastic (or biphasic) materials that are composed of a linear compressible solid phase, permeated by a viscous fluid. As an example, we analytically calculate the time-dependent net force on a rigid sphere in response to point forces applied to the elastic network and the Newtonian fluid phases of the biphasic material. We show that when the point force is applied to the fluid phase, the net force on the sphere evolves over time scales that are independent of the distance between the point force and the sphere; in comparison, when the point force is applied to the elastic phase, the time scale for force development increases quadratically with the distance, in line with the scaling of poroelastic relaxation time. Finally, we formulate and discuss how the reciprocal theorem can be applied to other areas, including (i) calculating the network slip on the sphere's surface, (ii) computing the leading-order effects of nonlinearities in the fluid and network forces and stresses, and (iii) calculating self-propulsion in biphasic systems.
The peculiar migration and rotational dynamics of non-spherical particles in non-Newtonian flows stem from the interplay between fluid rheology and fluid inertial effects. In this paper, the cross-flow migration of a neutrally buoyant oblate spheroid (aspect ratio $AR = 0.5$) immersed in the elasto-inertial duct flow is investigated by particle-resolved simulations with the immersed boundary method. Different from spherical particles, due to the orientation-dependent lift force, the oblate spheroid migrates in an oscillating manner in the duct. The travelling period for particles reaching the duct centreline undergoes a non-monotonic change with elastic number, revealing the existence of a critical elastic number governing the migrating efficiency of oblate particles within the present flow system. For the particle rotation and orientation, the present results indicate that the particle rotation rate and orbit drifting rate are both hindered by the fluid elasticity. With increasing the fluid elasticity, three different orientation modes – log-rolling mode, kayaking-like mode and longside-flow alignment mode – are observed successively during the elasto-inertial migration of the oblate spheroid. Potentially, the present results could be used to design the rheology-based controlling strategy for guiding particles to achieve optimal focusing and orientation in microfluidic applications without the need for external forcing fields.
High-resolution simulations of gravity currents in the lock-exchange configuration are conducted to study the flow within the head. The simulations exhibit the geometric features of the head as reported in the laboratory experiments and numerical simulations, and provide more detailed information on the flow within the head of a gravity current. The flow in the lower part of the head, where the lobes and clefts are forming at the leading edge, is qualitatively different from but interconnected to the flow in the upper part of the head, where steepening bulges are protruding from the upright surface above the clefts. Interestingly, regions of positive and negative streamwise vorticity are observed not only in the lower part of the head but also in the upper part of the head at staggered spanwise locations. We have shown that both the streamwise vorticity at the leading edge of the lobes in the lower part of the head and the streamwise vorticity at the steepening bulges in the upper part of the head are contributed from the twisting of spanwise vorticity into the streamwise direction, due to the geometric features of the lobes and the steepening bulges, and contributed from the baroclinic production of vorticity. Our results from visualization using tracers indicate that the ambient fluid ingested in and rising from the clefts is being swept towards the leading edge of a gravity current before being carried upwards from the leading edge to the upright surface above the left and right neighbouring lobes. Furthermore, the heavy fluid inside a lobe may descend towards the bottom boundary, move forward towards the leading edge and outwards towards the neighbouring clefts, and ultimately be carried upwards to the upright surface above the left and right neighbouring lobes. With the knowledge that the erosive power of a gravity current is concentrated in the head region, it is plausible that the bed material, once resuspended by a gravity current, may be lifted up away from the bottom boundary and be dispersed in both the streamwise and spanwise directions. The present study complements existing findings in the literature and provides new insights into the three-dimensional flow field within the head of a gravity current.
On November 8, 2022, the Court of Justice of the European Union (CJEU) rendered a preliminary ruling in response to a request from the Administrative Court of Schleswig-Holstein, Germany. The request pertained to the interpretation of Article 9(3) of the Convention on Access to Information, Public Participation in Decision-Making and Access to Justice in Environmental Matters (Aarhus Convention). The CJEU held that Article 9(3) of the Aarhus Convention must be interpreted as precluding a situation where an environmental association is unable to challenge an administrative decision before a national court.
This paper explores the (de-)routinisation of employment structure in developing countries, through the case of Morocco. We investigate employment (de-)routinisation from an often-overlooked perspective, aiming to elucidate the interplay between the dynamics of occupational employment composition by the level of routine tasks intensity and two structural aspects: premature deindustrialisation and the prevalence of informal labour.
Our findings, based on tertile analysis and regressions, do not fully support the hypothesis of employment structure de-routinisation. At the same time, we could not identify a clear process of routinisation similar to that observed in developing countries undergoing the first stage of the traditional structural transformation process. Rather, we identified an inverted U-shaped pattern in the dynamics of occupational employment, indicative of a rise in intermediate routine-intensive occupations.
We emphasise two key factors, with opposite effects that have contributed to this atypical pattern: The first aspect is premature deindustrialisation, which according to our shift-share decomposition, has adversely affected highly routine-intensive jobs, contrasting with the routinisation trend observed in countries that have experienced a more traditional process of structural transformation. The influence of premature deindustrialisation in terms of de-routinisation is somewhat mitigated by the increasing prevalence of occupations demanding intermediate routine tasks, particularly within the services and construction sector. Regarding the second structural aspect – the prevalence of informal labour – our three-way interaction model indicates a lower susceptibility of informal jobs to de-routinisation compared to their formal counterparts within the same industry. Consequently, the prevalence of informal employment has slowed down the process of de-routinisation of employment structure.
Issues of ‘disability’ and ‘ageing’ are usually approached separately in theorising, activism and policy making. Yet people with disabilities age and many people will experience disability if they live long enough. Human rights approaches to disability enshrined in the UN Convention on the Rights of Persons with Disabilities (CRPD) are not often applied to older people experiencing disability. This article presents findings of a systematic qualitative analysis of reports made by 28 European states to the UN Committee on the Rights of Persons with Disabilities, the independent body that monitors CRPD implementation, focusing particularly on Article 19 CRPD (‘Living independently and being included in the community’). While states’ reports refer to older people or ageing in different contexts, their approach can be characterised as ambivalent. Reports tend to constitute older people experiencing disability as ‘older’ rather than ‘disabled’; they do not demonstrate a thorough engagement with disability experienced in older age, and display a limited focus on people ageing with lifelong disability. Several reports detail exclusions of ‘older people’ from disability supports to live in the community and some exclude impairments associated with ageing from definitions of what ‘disability’ is. The reports provide almost no evidence of consultation with organisations working on ageing. The article concludes that while the CRPD’s potential to contribute to realising rights for older people with disabilities is under-recognised among scholars and non-governmental organisations, the fact that states refer to older people in their reporting under the CRPD provides a starting point for more engagement.
Enhanced dietary Ca intake linearly increases intestinal Ca absorption in pigs, but not in broilers, suggesting potential differences in whole body Ca homeostasis. To determine the role of kidney in Ca homeostasis in these species, we varied in growing pigs in experiment (Exp) 1, the dietary Ca content 2·0 v. 9·6 g/kg and phytase 0 v. 500 FTU/kg, in broilers, in Exp 2 the dietary Ca/retainable P from 1·3 to 2·8 and phytase 0 v. 1000 FTU/kg, and in Exp 3 dietary Ca/P from 0·50 to 1·75. Increasing dietary Ca reduced renal mRNA expression of Ca-related transporters (TRPV5, TRPV6, CaBP-D28k and NCX1) and tight junctions (CLDN-12 and −16) in pigs, indicating Ca reabsorption was reduced to maintain Ca homeostasis. In broilers (Exp 2), high dietary Ca increased renal TRPV6, CaBP-D28k and CLDN-2 mRNA, indicating an increased capacity for Ca reabsorption. Moreover, the effect of dietary Ca was enhanced by inclusion of dietary phytase in pigs but reduced in broilers. Furthermore, increasing dietary Ca upregulated inorganic phosphate transporter 1 (PiT-1), while phytase downregulated xenotropic and polytropic retrovirus receptor 1 (XPR1) mRNA expression in pigs; in broilers, dietary Ca downregulated renal mRNA expression of Na-dependent phosphate transporter IIa (NaPi-IIa), PiT-1, PiT-2 and XPR1, while phytase downregulated NaPi-IIa but upregulated PiT-2 and XPR1 mRNA expression. In Exp 3, Ca/P effect on transporter mRNA expression was largely consistent with Exp 2. In conclusion of this study, together with previously measured data about Ca and P homeostasis, in pigs the kidneys play a more regulatory role in Ca homeostasis than in broilers where the intestine is more important for regulation.
Thromboembolism is a complication in paediatric patients with CHD requiring cardiac surgery. Previous research has focused on post-operative thromboembolism. This study aimed to describe thromboembolism frequency before or after cardiac surgery in children with CHD.
Methods:
We performed a single-centre retrospective study from October 2020 to June 2023 (inclusive). Patients were eligible for inclusion if they were <21 years of age and underwent cardiac surgery. Outcomes of interest included the occurrence and characteristics of thromboembolism in the 12 months before and after surgery, antithrombotic therapies, recurrent thromboembolism, and clinically significant bleeding.
Results:
Among 260 patients included, 35 (13.5%) developed an index thromboembolism. Twelve (34.3%) patients had an index thromboembolism <12 months before surgery and 23 (65.7%) had an index thromboembolism <12 months after surgery, including 8 (22.9%) patients who had thromboembolism during both exposure periods. The median interquartile range (IQR) time of thromboembolism relative to cardiac surgery was –26 (–4 to –140) days and 15 (4 to 41) days, respectively. Seven (20%) patients had arterial, 18 (51.4%) venous, and 3 (8.6%) had both arterial and venous thromboembolism. Median (IQR) antithrombotic therapy duration was 49 (24–84) days. Nine (25.7%) patients developed recurrent thromboembolism and five (14.3%) patients experienced clinically significant bleeding.
Conclusions:
The risk of thromboembolism and recurrence is high both before and after cardiac surgery among paediatric patients with CHD. Prospective multi-centre studies should seek to identify risk factors for preoperative and postoperative thromboembolism to inform the design of future risk-stratified thromboembolism prevention trials in children with CHD.
Ductal stenting in late presenters with transposition of great arteries with intact ventricular septum retrains the left ventricle before arterial switch operation. However, the experience is limited for its efficacy and safety. This study aims to highlight the efficacy and safety of ductal stenting for retraining the left ventricle.
Methods:
Eight children with transposition of great arteries-intact ventricular septum and regressed left ventricle underwent ductal stenting. Serial echocardiographic measurements of left ventricle shape, mass, volume, free wall thickness, and function were done, and arterial switch operation was performed once the left ventricle was adequately prepared. Post-operative outcome in terms of duration of mechanical ventilation, ICU stay, and improvement in left ventricle function were monitored.
Results:
The procedure was successful in all patients. Babies were divided into two groups on basis of age at ductal stenting (group 1 age less than 90 days and group 2 age more than 90 days) and were evaluated for the degree of left ventricle retraining as evidenced by echocardiographic parameters and post-operative variables. The left ventricle posterior wall thickness and mass index after ductal stenting increased significantly in both the groups. Postoperatively, one baby of group two expired after seven days due to severe left ventricle dysfunction. Rest babies had an uneventful post-operative ICU stay with no statistical difference in the duration of invasive mechanical ventilation or ICU stay. On six-month follow-up, all surviving babies were doing well with normal left ventricle function.
Conclusion:
Ductal stenting is a good alternative measure as compared to surgical procedures for left ventricle retraining in transposition of great arteries with regressed left ventricle.
Using a national audit of mayors in the United States, this paper examines responsiveness to Latine lesbian and gay constituents who request that their city issue an LGBTQ pride proclamation. Drawing on theories of intersectionality, descriptive representation, and political institutions, we articulate the conditions under which mayors are responsive to public-facing constituency service requests to issue LGBTQ pride proclamations. We find that mayors are more responsive to requests from lesbian couples than gay couples. In addition, baseline responsiveness to our inquiry was influenced by mayors’ identity characteristics. LGBTQ mayors were more likely to respond than non-LGBTQ mayors, but Latine mayors were less likely to respond than non-Latine mayors. In addition, mayors who represent cities where nondiscrimination ordinances protect LGBT people from discrimination were more responsive than mayors who represent cities where LGBT people are not protected from discrimination. These findings demonstrate how intersectional frameworks can advance audit experiments and that shared descriptive characteristics do not inevitably translate into responsiveness, a common assumption in single-axis studies of representation.