To save content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about saving content to .
To save content items to your Kindle, first ensure no-reply@cambridge.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about saving to your Kindle.
Note you can select to save to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
This paper examines some institutions of French public law and their transformations induced by European integration. It shows how institutions rooted in a specific political culture that long aimed at ensuring political liberty through the active role of la loi have been challenged by other institutions designed in the first place to protect civil liberties. It argues that the loi-based republican institutions of public law, that were inherited from the French Revolution and 18th century political thinkers, such as Montesquieu and above all Rousseau, have been significantly reshaped. That did not happen through politics, nor through another ‘French-style’ revolution. Ironically enough, it happened more modestly through law, within the meaning of le droit (and courts) as opposed to la loi (and the legislator), that is through those very means of political change that Republican France had consistently rejected ever since the Revolution. The French example showcases how paradigmatic political changes, from messianic republicanism to global constitutionalism, may thus occur, without a revolution, through the smooth medium of (European) law.
To evaluate the effectiveness and acceptability of ventilation interventions in naturally ventilated hospitals in Liberia.
Design:
Difference-in-differences analysis of pre- and post-air changes per hour of intervention and control spaces.
Setting:
Hospitals in Bong and Montserrado Counties, Liberia.
Participants:
Seventy patient care spaces were evaluated at baseline. Six spaces underwent physical intervention modifications, while 2 spaces were assessed for indirect effects and 2 others used as controls. Healthcare workers were interviewed to assess ventilation knowledge and acceptability.
Interventions:
Ventilation interventions included the installation of window screens, louvered doors and windows, and wind turbines.
Methods:
We measured carbon dioxide levels with portable meters and documented persons per room to estimate per-person ventilation rates in both L/s/person for the initial assessment and air changes per hour (ACH) in the intervention. Measurements were taken in patient care spaces in 7 hospitals in Liberia. Healthcare worker acceptability was evaluated via structured interviews.
Results:
Two-thirds (46/70) of patient care spaces were below the WHO-recommended ventilation threshold of 60 L/s/person. Six spaces underwent ventilation interventions, including placement of window screens (3), wind turbines (2), and louvered doors and windows (1), with 2 additional spaces being indirectly affected by these interventions and 2 more spaces serving as controls. Ventilation improved by an average of 2 ACH in the spaces with wind turbines and louvered doors and windows. Overall acceptability of the interventions was high.
Conclusions:
Implementing interventions to improve ventilation in naturally ventilated healthcare facilities is efficacious, feasible, and acceptable, though longer-term evaluations should assess sustainability.
Ammonoid cephalopods are excellent model systems for evolutionary biomechanics due to their volatile evolutionary dynamics and remarkable fossil record. During the Mesozoic marine revolution, natural selection increasingly favored ammonoid shells with specific ranges of ornamentation patterns (projections that influence surface roughness). While this evolutionary pattern has been attributed to enemy-driven evolution (i.e., escalation), many morphologies lack clear defensive roles. Using a combination of 3D modeling, physical experiments, and computer simulations, we investigate these patterns from a hydromechanical perspective. We model theoretical morphologies along a continuum of increasing ornamentation coarseness. Neutrally buoyant, 3D-printed models, weighted to match the mass distribution of their virtual counterparts, demonstrate that coarser patterns progressively attenuate rocking motions. Flow visualization experiments reveal these coarser patterns produce higher energy dissipation rates in the disturbed fluid. Computational fluid dynamics simulations were performed to characterize the hydrodynamic costs of ornamentation patterns over the majority of biologically relevant swimming speeds and shell sizes for planispiral ammonoids. Only the coarsest categories incur substantial increases in hydrodynamic drag. However, ornamentation patterns with intermediate coarseness effectively avoid this physical trade-off, experiencing dynamic stabilization without considerably reducing swimming efficiency. These trade-off-defying morphologies were progressively favored during the Mesozoic, becoming more abundant than others by the end of this era. Ultimately, these experiments highlight important hydromechanical selective pressures involved in ammonoid evolutionary trends and some fundamental constraints on aquatic locomotion more broadly.
To characterize the dietary patterns of Marshallese mothers of young children in Northwest Arkansas, informing the cultural adaptation of nutrition education curricula.
Design:
An exploratory cross-sectional study was conducted, in which Marshallese women with children under 12 months completed 3 telephone-administered 24-hour dietary recalls with a trained bilingual Marshallese interviewer. Diet quality was characterized using the Healthy Eating Index (HEI)-2020. A food-level analysis identified top food groupings contributing to total energy and HEI-2020 components.
Setting:
Northwest Arkansas.
Participants:
Marshallese mothers with children < 12 months.
Results:
29 women were recruited, 20 completed 2 or 3 dietary recalls. Median age was 25·5 years. Diet quality by HEI-2020 was 46·4 (max score 100). White rice was the top contributor to total energy; high seafood/plant protein and fatty acid diet quality component scores were influenced by high fish intakes.
Conclusions:
Diet quality was low. Key adaptations include reducing rice portion sizes, while emphasizing lean proteins and fruits/vegetables. Cultural adaptation of nutrition education is essential to improve diet quality among communities with varying dietary practices.
Following the trajectories of vaccines against foot-and-mouth disease (FMD) in France and Britain up to the 1960s, this paper will show how vaccine efficacy has two meanings: 1) technical – or experimental – which refers to test protocols and regimes of evidence, and 2) practical – or experiential – which refers to the experience various actors have of diseases and their direct or indirect impacts on society and the economy, as well as on representations and imaginaries they share about diseases, vaccines, and vaccination. The assessment protocols in the two countries are analysed to show how these two meanings are deeply intertwined and influence the different public policies chosen by each country. Although statistically assessed, the efficacy of the same vaccines appears situated, depending not only on regimes of evidence but also on the reality of agricultural practices, on national stock exchanges, and on various imaginaries about animal health and the absence of disease that differ between and within countries. As a consequence, this analysis reveals how public policies regarding vaccination do not always come from governmental incentives but can also emerge from private and local initiatives.
To assess the association between coffee consumption and life expectancy among the US adults.
Design:
Prospective cohort.
Setting:
National representative survey in the United States, 2001–2018.
Participants:
A total of 43 114 participants aged 20 years or older with complete coffee consumption data were included from National Health and Nutrition Examination Survey 2001–2018.
Results:
Over a median follow-up of 8·7 years, 6234 total deaths occurred, encompassing 1929 deaths from CVD and 1411 deaths from cancer. Based on the nationally representative survey, we found that coffee consumption is associated with longer life expectancy. The estimated life expectancy at age 50 was 30·06 years (95 % CI, 29·68, 30·44), 30·82 years (30·12, 31·57), 32·08 years (31·52, 32·70), 31·24 years (30·29, 32·19), and 31·45 years (30·39, 32·60) in participants consuming 0, ≤ 1, 1 to ≤ 2, 2 to ≤ 3, and > 3 cups of coffee per day, respectively. Consequently, compared with non-coffee drinkers, participants who consumed 1 to ≤ 2 cups/day had a gain of 2·02 years (1·17, 2·85) in life expectancy on average, attributable to a 0·61-year (29·72 %) reduction in CVD deaths. Similar benefits were found in both males and females.
Conclusion:
Our findings suggest that moderate coffee consumption (approximately 2 cups per day) could be recommended as a valuable component of a healthy diet and may be an adjustable effective intervention measure to increase life expectancy.
This article explores the intersection of Cold War geopolitics, cultural psychiatry, and migration in Taiwan from the mid-1940s to the 1970s. Building on recent scholarship in cultural psychiatry and Cold War science, it examines how geopolitical tensions shaped psychiatric knowledge production in East Asia. Focusing on the psychological and social impact of the 1949 mass migration, when over a million Chinese immigrants arrived in Taiwan, alongside the clinical and academic work of Taiwanese psychiatrists, the study highlights how migration and societal upheaval became central research concerns. Operating under the authoritarian Kuomintang regime and within the constraints and opportunities of international politics, Taiwanese psychiatrists – most of whom were native-born with colonial backgrounds – drew on intellectual traditions from imperial Japan, fascist Germany, and the Cold War Western bloc. Navigating both global psychiatric discourses and local concerns, they positioned themselves as key contributors to the international development of psychiatric research. While their portrayals of Chinese character structure and family dynamics sometimes reflected essentialist views, their work also demonstrated a nuanced awareness of historical change and contemporary realities during a period of intense political repression and uncertainty. By analysing archival sources and medical texts, this article illuminates the complex interplay between geopolitics and psychiatric knowledge production in Cold War Taiwan.
The operating room scheduling (ORS) problem deals with the optimization of daily operating room surgery schedules. It is a challenging problem subject to many constraints, like to determine the starting time of different surgeries and allocating the required resources, including the availability of beds in different department units. Recently, solutions to this problem based on answer set programming (ASP) have been delivered. Such solutions are overall satisfying but, when applied to real data, they can currently only verify whether the encoding aligns with the actual data and, at most, suggest alternative schedules that could have been computed. As a consequence, it is not currently possible to generate provisional schedules. Furthermore, the resulting schedules are not always robust. In this paper, we integrate inductive and deductive techniques for solving these issues. We first employ machine learning algorithms to predict the surgery duration, from historical data, to compute provisional schedules. Then, we consider the confidence of such predictions as an additional input to our problem and update the encoding correspondingly in order to compute more robust schedules. Results on historical data from the ASL1 Liguria in Italy confirm the viability of our integration.
The presence of children in eighteenth-century English voluntary hospitals is an area of increasing interest and attention. The Northampton Infirmary admission records detail inpatient and outpatient ages from 1744 to 1804, allowing for longitudinal investigations of children in the institution. The most common distempers affecting children were surgical infections, infectious diseases, and skin diseases; fifty-six per cent of the child patients were male and 43.3 per cent were female. Nearly seventy-five per cent of children left the hospital ‘cured’. This article outlines the Northampton Infirmary Eighteenth Century Child Admission Database, and demonstrates how the patterning of distempers within and among children provides insight into the health journeys of eighteenth-century children through the lens of their bodies, their parents, and their institutional recommenders.
This article contributes to research on pragmatic borrowings through its exploration of their prosodic features in interactional turns. The pragmatic borrowings focused on are actual or enacted responses that demonstrate a stance towards the interlocutor’s previous turn. The data are drawn from podcast conversations in Finland Swedish. The qualitative exploration of the data, which draws on principles from Interactional Linguistics and uses sequential and acoustic analyses, focuses on an in-depth analysis of four examples of response tokens. Our analysis illustrates that borrowed response tokens are not used frequently, but when they are used, they are marked by speakers prosodically, rendering them stylistically salient within the context of the interaction. The borrowed response tokens demonstrate specific interactional meanings, such as affect, humor, farce and upgrading. These findings demonstrate that, like other pragmatic borrowings, responses are integrated into the overall repertoire of the receiving speech community, serving as stylistic variants alongside heritage forms.
According to the orthodox comparativist approach in rational choice theory, the ultimate conative basis for an agent’s preference ordering – and thus for their rational choice – is their comparative evaluation among competing options. However, it has been shown extensively in experimental psychology that an agent’s judgments about an option can be distorted by the contrast effects from their contextual reference point, which can sometimes be provided by the very competing option that they compare with. Such contrast effects from competing option, I argue, raise a new problem for comparativism: Sometimes an agent’s comparative evaluation might favor an option A over another option B only because their judgments about A’s appealing intrinsic features are distorted by B’s contrast effects. Such a comparative evaluation from contrast effects, however, is not only epistemically defective but also likely to lead to post-choice disenchantment with option A once the contrast effects from the competing option B are removed. While comparativists can either rationalize the choices made on the basis of comparative evaluations from contrast effects or idealize the type of comparative evaluations they appeal to, I argue that both strategies still face significant problems.
Visible satellite imagery (VIS) is essential for monitoring weather patterns and tracking ground surface changes associated with climate change. However, its availability is limited during nighttime. To address this limitation, we present a discrete variational autoencoder (VQVAE) method for translating infrared satellite imagery to VIS. This method departs from previous efforts that utilize a U-Net architecture. By removing the connections between corresponding layers of the encoder and decoder, the model learns a discrete and rich codebook of latent priors for the translation task. We train and test our model on mesoscale data from the Geostationary Operational Environmental Satellite (GOES) West Advanced Baseline Imager (ABI) sensor, spanning 4 years (2019 to 2022) using the Conditional Generative Adversarial Nets (CGAN) framework. This work demonstrates the practical use of a VQVAE for meteorological satellite image translation. Our approach provides a modular framework for data compression and reconstruction, with a latent representation space specifically designed for handling meteorological satellite imagery.
Clinicians across medical disciplines are intimately familiar with an unusual feature of descriptive diagnoses. The diagnostic terms, despite their non-aetiological nature, seem to offer an explanatory lens to many patients, at times with profound effects. These experiences highlight a striking, neglected and unchristened medical phenomenon: the therapeutic effect of a clinical diagnosis, independent of any other intervention, where clinical diagnosis refers to situating the person’s experiences into a clinical category by either a clinician or the patient. We call this the Rumpelstiltskin effect. This article describes this phenomenon and highlights its importance as a topic of empirical investigation.
Humans often participate in physically harmful and demanding rituals with no apparent material benefits. Although such behaviours have traditionally been explained using the lens of costly signalling theory, we question whether the canonical theory can be applied to the case of human cooperative signals and introduce a modification of this theory based on differential benefit estimation. We propose that along with cooperative benefits, committed members also believe in supernaturally induced benefits, which motivate participation in extreme rituals and stabilize their effects on cooperative assortment. Using Thaipusam Kavadi as a prototypical costly ritual, Tamil (ingroup) and Christian (outgroup) participants in Mauritius (N = 369) assessed the cost and benefits of Kavadi participation or hiking. We found that ingroup participants estimated material costs as larger than outgroups, physical costs as lower, and benefits as larger. These findings suggest that estimated costs may vary by modality and cultural expectations (e.g. Kavadi participants are not supposed to display pain), while supernaturally induced benefits were consistently reported as larger by ingroups compared to outgroups. We conclude that differential estimation of ritual benefits, not costs, are key to the persistence of extreme rituals and their function in the assortment of committed members, underscoring the role of differential estimation in the cognitive computation of signal utility.
Endothelial progenitor cells (EPCs) are key regulators of vascular homeostasis in both health and disease, playing a crucial role in regenerating the human vascular lining throughout life. These circulating cells can differentiate into mature endothelial cells and are increasingly recognized as important biological markers of vascular function and cumulative risk for various diseases, including cardiovascular conditions. In recent decades, the role of EPCs, particularly the endothelial colony-forming cells (ECFCs) subtype, in pregnancy-related disorders and maternal and neonatal endothelial health has garnered significant attention. Evidence suggests that ECFCs may serve as predictor of future endothelial health in women and their offspring following pregnancy complications, making them particular relevant for research and therapeutic applications in adulthood, as well as potential indicators of vascular health. This review summarizes the evidence on EPCs, specifically ECFCs, as biomarkers of endothelial health in pregnancy, pregnancy-related diseases and ageing, with a focus on maternal and foetal endothelial abnormalities that may serve as prognostic factors for the development of future diseases.
A realization is a triple, $(A,b,c)$, consisting of a $d-$tuple, $A= (A_1, \cdots , A_d )$, $d\in \mathbb {N}$, of bounded linear operators on a separable, complex Hilbert space, $\mathcal {H}$, and vectors $b,c \in \mathcal {H}$. Any such realization defines an analytic non-commutative (NC) function in an open neighbourhood of the origin, $0:= (0, \cdots , 0)$, of the NC universe of $d-$tuples of square matrices of any fixed size. For example, a univariate realization, i.e., where A is a single bounded linear operator, defines a holomorphic function of a single complex variable, z, in an open neighbourhood of the origin via the realization formula $b^{*} (I-zA)^{-1} c$.
It is well known that an NC function has a finite-dimensional realization if and only if it is a non-commutative rational function that is defined at $0$. Such finite realizations contain valuable information about the NC rational functions they generate. By extending to infinite-dimensional realizations, we construct, study and characterize more general classes of analytic NC functions. In particular, we show that an NC function is (uniformly) entire if and only if it has a jointly compact and quasinilpotent realization. Restricting our results to one variable shows that a formal Taylor series extends globally to an entire or meromorphic function in the complex plane, $\mathbb {C}$, if and only if it has a realization whose component operator is compact and quasinilpotent, or compact, respectively. This motivates our definition of the field of global (uniformly) meromorphic NC functions as the field of fractions generated by NC rational expressions in the ring of NC functions with jointly compact realizations. This definition recovers the field of meromorphic functions in $\mathbb {C}$ when restricted to one variable.
This article documents adverse selection in Ginnie Mae issuers’ early buyout decisions. Conditional on default, we find a 1 percentage point increase in interest rate spread increases the probability of an early buyout by 7–9 percentage points. Issuers buy out higher interest rate spread loans because they generate greater economic gains when they reperform. We illustrate how issuers acquire private soft information that provides direct insight into the likelihood of reperformance. Although the soft information is ostensibly collected on behalf of investors during the delinquent loan servicing process, issuers can exploit the information in their early buyout decisions.
Tritrichomonas foetus causes bovine trichomonosis, a venereal disease that reduces productivity in naturally mated cattle. Its high prevalence in Northern Australian herds underscores the need for a locally made strain-specific vaccine. This study developed and tested a whole-cell killed T. foetus vaccine using the Queensland isolate TfOz5 (vaccine strain) and TfOz-N36 (Northern Territory isolate) as the challenge strain. The heat-inactivated vaccine, adjuvanted with Montanide ISA 61 VG, was administered subcutaneously in 2 doses (5 × 10⁷ cells/dose) at a 1-month interval to mature bulls (n = 6) (4–7 years old), while controls (n = 6) (4–8 years old) received adjuvant with PBS. Bulls were experimentally challenged intrapreputially with live cultures of T. foetus at 2- and 6-months post first vaccination. A therapeutic trial with T. foetus-positive, persistently infected mature bulls (n = 10) (4–7 years old) used the same vaccine regime without the subsequent T. foetus challenges. The vaccine was found to be safe, causing only mild local reactions. The vaccine challenge experiment demonstrated similar duration of T. foetus positivity, confirmed by quantitative polymerase chain reaction (qPCR), compared to controls (94 vs. 106 days, P = 0.73). In the therapeutic experiment, 2/10 treated bulls tested negative for T. foetus at the end of the trial, while the remaining eight remained positive. Vaccinated bulls in both experiments showed significantly elevated serum anti-T. foetus IgG antibody levels, confirming the vaccine’s immunogenicity. These findings demonstrate that the experimental vaccine is safe and capable of eliciting a specific immune response in mature bulls.
These excerpts from Inbetweenness, an upcoming hopepunk novel, intertwine eco-social justice narratives and Indigenous education through climate fiction. Inbetweenness challenges Western-centric paradigms by highlighting diverse voices and posthumanist perspectives, focusing on the tension between contemporary environmental crises and Indigenous knowledge systems. It features characters like Joanne Penderwith, a graduate student navigating social justice, ecological connection, and decolonial praxis, inviting readers to reflect on allyship and positionality within activism. The novel also juxtaposes human-centric actions with the voices of other-than-human entities, using multi-species ethnography to embody ecological storytelling. A pivotal segment details Joanne’s transformative experience at a salmon ceremony led by the W̱SÁNEĆ First Nations, showcasing the resilience of Indigenous practices and their potential to guide sustainable futures. Inbetweenness uses fiction-based research methods grounded in 20 years of transdisciplinary research. It critiques performative allyship and advocates for authentic relationships with Indigenous communities, proposing a hopeful approach to environmental education and climate action.