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Background. Despite the growing recognition of adolescent suicide as a pressing concern, traditional methods for identifying suicide risk often fail to capture the complex interplay of socio-ecological and psychological factors. The advent of machine learning (ML) offers a transformative opportunity to improve suicide risk prediction and intervention strategies. Objective. This study aims to utilize ML techniques to analyze socio-ecological and psychological risk factors to predict suicide ideation, plans and attempts among a nationally representative sample of Ghanaian adolescents. Methods. A cross-sectional survey was conducted with 1,703 adolescents aged 12–18 years across Ghana measuring psychological factors (depression symptoms, anxiety symptoms etc) and socio-ecological factors (bullying, parental support etc) using validated measures. Descriptive statistics were conducted and random forest and logistic regression models were employed for suicide risk prediction, i.e., ‘ideation, plans and attempts’. Model performance was evaluated using accuracy, sensitivity, specificity and feature importance analysis. Results. Psychological factors such as depression symptoms (r = .42, p < .01), anxiety (r = .38, p < .01) and perceived stress (r = .35, p < .01) were the strongest predictors of suicide ideation, plans and attempts, while parental support emerged as a significant protective factor (r = −.34, p < .01). The random forest model demonstrated good predictive performance (accuracy = 78.3%, AUC = 0.81). Gender differences were observed. Conclusions. This study is the first to apply ML techniques to a nationally representative dataset of Ghanaian adolescents for suicide risk prediction, i.e., ‘ideation, plans and attempts’. The findings highlight the potential of ML to provide precise tools for early identification of at-risk individuals.
An extensive survey of North American catostomid fishes yielded insights into the diversity, host specificity and phylogenetic relationships of monopisthocotylans belonging to Pseudomurraytrematidae. Parasites were recorded from 14 of 16 host species surveyed. In total, 22 species of Anonchohaptor, Icelanonchohaptor and Pseudomurraytrema were collected, including 7 new species. Most species were recovered from gills, whereas two Icelanonchohaptor species were found on fins. Phylogenetic analyses based on 28S rDNA support the monophyly of Pseudomurraytrematidae and its sister relationship to Diplectanidae. Within the family, Pseudomurraytrema asiaticum – a parasite of the East Asian fish Myxocyprinus asiaticus – was recovered as sister to the clade of Nearctic pseudomurraytrematids, a placement that may reflect geographic and host-associated separation. The remaining Pseudomurraytrema species parasitize North American Catostominae and form a well-supported clade sister to the clade comprising species of Anonchohaptor and Icelanonchohaptor, primarily associated with Ictiobinae. Under this topology, Pseudomurraytrema, as currently circumscribed, may be paraphyletic. Relationships between morphologically similar species of Anonchohaptor and Icelanonchohaptor remain unresolved: in the 28S tree, Anonchohaptor is paraphyletic (with Icelanonchohaptor nested within it), whereas the concatenated 18S–ITS1–28S analyses recover a single clade with Icelanonchohaptor (2 spp.) sister to the remaining species of Anonchohaptor. The parasite phylogeny broadly reflects host relationships, though several incongruences point to historical host switching. Morphological data also support the monophyly of Pseudomurraytrematidae via a synapomorphic male copulatory organ (U-shaped copulatory tube with a submedial spine, 3-ramus accessory piece), indicating structural conservatism within this family.
In 1911, Italy invaded the region now known as Libya, then part of the Ottoman Empire, as part of a larger Italian colonizing foray into northern Africa. Many scholars have pointed out in recent years how intense the sonic environments of war can be, and the Italo-Turkish War of 1911–12 was no exception. Not only was the war itself full of sound and sonic media such as gramophones and telephones, the narration of the war, including most (in)famously that of Futurist author F.T. Marinetti, focused from the outset on the sonic intensities of the conflict. In addition, the war became a site for the cultivation of sonic media: Guglielmo Marconi not only deployed his radio technology for the Italian cause, he personally travelled to Libya to test and refine radio in the unique geographies there. In this article, I consider these Italian-centric narratives of war alongside accounts of the sonic experiences of the Arab and Ottoman Turkish forces in their resistance to the Italian occupation, considering the sonic techniques deployed both for and against Italian colonialism. I focus on three particular sonic techniques of that resistance: first, ‘counterlistening’, or ways of listening that subvert empire’s auralities; second, ululation (mostly by women) on the battlefield and beyond; and third, jihad, especially its sonic articulations as a set of declarations, battle cries, religious chanting, and even poetry. For both sides, sound played a much greater role in the war than just being a by-product of activity; these sonic techniques both shaped the war and were shaped by it, producing new forms of sonic experience that played important roles in constituting the colonial and anticolonial in Libya.
Both skill-biased and routine-biased technological changes risk disrupting employment in Australia, particularly through persistent effects after an economic downturn. Soft skills are considered valuable for employees to reduce unemployment risk from these technological biases, as these skills contribute to employment in skilled and non-routine jobs that are difficult to automate. We investigate how soft skills affected the risk of unemployment from the Global Financial Crisis (GFC) using the Household, Income and Labour Dynamics in Australia (HILDA) longitudinal dataset to understand whether these skills could reduce unemployment risk and similar negative employment outcomes for workers during economic disruptions, including the following years during the recovery. We find that the soft skill measures of social capital and low task repetitiveness are associated with lower unemployment, overskilling, and underutilisation risk. The association between social capital and underemployment also strengthened after the downturn. This did not begin immediately after the GFC but instead from 2013 onwards, after the end of the mining boom that had supported Australia during the GFC.
Plants are under constant genetic siege. From viruses and bacteria to transposable elements within their genomes, cells must contend with foreign genetic material. Besides these natural threats, modern biotechnology adds complexity by introducing transgenes to plants. While the integration of such DNA can enhance genetic diversity and confer desirable traits, its foreign origin is typically recognised by the plant cell as a signal of invasion and therefore targeted by the repressive mechanisms. Epigenetic silencing is a central strategy and involves the methylation of DNA and histones. A critical trigger of this silencing is the generation of small interfering RNAs (siRNAs). Although the role of siRNAs in maintaining epigenetic silencing is well established, the initial steps that lead to their production remain incompletely understood. This review discusses the key discoveries on how plant cells recognise foreign nucleic acids and initiate epigenetic silencing, contributing to our broader understanding of genome integrity and defence.
This study examines the ramifications engendered by the personalisation welfare initiative, denominated as ‘Individualised Budgeting’, upon the welfare service framework in Israel. Adopting a supply-side perspective, the study employed qualitative, in-depth interviews with service providers to scrutinise potential successes and failures in service systems. The study’s methodology employed a multi-criteria policy analysis based upon the analytical theoretical framework of Gilbert and Terrell’s welfare service delivery system analysis. Results revealed that while service integration and systematic function distribution align well with the programme, accessibility and accountability only partially fit, suggesting a need for improved regulatory frameworks. New criteria, including economic viability for private suppliers and investment in innovative services, also emerged. Addressing these market inadequacies requires State investment in technological innovations to ensure an effective service delivery system.
Behaviours that challenge are highly prevalent in children with an intellectual disability and can be detrimental to their quality of life and opportunities.
Aims
The systematic review aimed to investigate the effectiveness of current interventions in reducing behaviours that challenge in children with an intellectual disability (≤18 years-old).
Method
We searched five databases (PsychINFO, MEDLINE, Embase, Web of Science and CINAHL) on 26 April 2022 and 1 July 2024, and identified 18 randomised controlled trials (1443 participants) eligible for inclusion since 2014 – 11 investigated non-pharmacological and 9 investigated pharmacological interventions. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool.
Results
Non-pharmacological interventions (mostly psychosocial) were significantly effective (Hedges’ g = −0.20; 95% CI [−0.35, −0.05]), whereas pharmacological interventions (including a wide range of drug classes and substances) were not (g = 0.03; 95% CI [−0.17, 0.24]). Studies using the Child Behaviour Checklist reported significant reductions (g = −0.18; 95% CI [−0.34, −0.02]), whereas studies using the Aberrant Behaviour Checklist did not (g = 0.04; 95% CI [−0.16, 0.25]). A random-effects meta-analysis indicated no overall significant reduction in behaviours that challenge (g = −0.12; 95% CI [−0.24, 0.00]).
Conclusions
It is important to note that most studies included were conducted in Western countries and had small sample sizes, and findings may be due to the outcome measures used. Findings support current recommendations that non-pharmacological interventions should be first-line treatment for behaviours that challenge in this population. Evidence highlighted the need for better quality, adequately powered randomised controlled trials.
Frank Samperi is a neglected twentieth-century American poet who produced a large body of poetry. Affiliated closely with Objectivist poetics through the mentorship of Louis Zukofsky, Samperi’s work is significantly influenced by the Catholic writings of Aquinas and Dante. With a commitment to linguistic self-reflexivity, an ethics of otherness, and a resistance to abstraction and identity thinking, Samperi’s work enhances and expands our understanding of the key traits of Objectivist poetics, often regarded as relying heavily on Judaic ideas and philosophies. As an Italian American Catholic, his poetry also demonstrates an immigrant’s compromise with Americanization, but an equally clear alignment with the emerging American poetic counterculture in the 1960s.
The growing integration of artificial intelligence (AI) and patient-reported digital tools (ePROMs and ePREMs) in palliative care offers new opportunities for personalised care yet also raises profound ethical and philosophical concerns. This paper examines how emerging technologies intersect with the concept of human dignity at the end of life, proposing an expanded notion of post-biographical dignity.
Methods
Ethical-philosophical analysis based on critical readings of AI ethics, narrative medicine, and the philosophy of technology.
Results
While digital tools such as ePROMs and ePREMs offer potential for richer, more person-centred care, they also risk reducing patients to data points and predictive profiles. Digital processes increasingly shape the narrative, vulnerability, and memory of the dying person. Post-biographical dignity calls for a reconceptualization of care that includes memory, relational continuity, and ethical engagement with digital remains.
Significance of Results
End-of-life care in the age of AI must move beyond autonomy-focused ethics to encompass the narrative, relational, and posthumous dimensions of dignity. A critical, philosophically informed ethics is essential to prevent depersonalisation in digitally mediated care.
In discussions on European Neogene continental chronology, the Kastellios Hill section has played an important role because of the presence of strata with planktonic foraminifers and strata with mammalian remains. With the primary papers written in the 1970s and 1980s, the time is ripe for an update on age and taxonomy of the murid rodents from Kastellios Hill by comparing the fauna with time-equivalent southern and central European faunas. This comparison results in a partly revised faunal list consisting of the dominant Progonomys mixtus n. sp., the less common Cricetulodon cf. C. hartenbergeri Freudenthal, 1967 and P. cathalai Schaub, 1938, and the rare P. hispanicus Michaux, 1971 and cf. Hansdebruijnia neutra (de Bruijn, 1976). Based on the updated species list and magnetic polarity data, the most probable age of the Kastellios Hill mammal localities is 9.3–9.1 Ma (Chron C4Ar.1r, late Vallesian, MN10). The genus Hansdebruijnia is narrowed down to two species in an ancestor–descendant relationship: the ancestral type species H. neutra, which is restricted to southeastern Europe and Anatolia, and the descendant species H. magna (Sen, 1977), representing a new combination and including ‘Occitanomys alcalai’ Adrover et al., 1988 and ‘O. debruijni’ (Hordijk and de Bruijn, 2009). H. magna colonized both southeastern and southwestern Europe.
Post-asymptotic giant branch (Post-AGB) and post-red giant branch (post-RGB) binaries with stable circumbinary discs provide key insights into late stellar and disc evolution, revealing how binary interactions shape disc structure and stellar surface composition. A defining trait of such systems is the observed underabundance of refractory elements in the stellar photosphere relative to volatile elements – photospheric chemical depletion – resulting from the star accreting volatile-rich circumstellar gas. In this study, we investigated the link between photospheric depletion and disc evolution by focusing on post-AGB/post-RGB binaries with low infrared excess (hereafter ‘faint disc’ targets). We analysed high-resolution optical spectra from HERMES/Mercator and UVES/VLT for 6 Galactic and 2 LMC targets. Using E-iSpec, we homogeneously derived atmospheric parameters and chemical abundances of 29 elements from carbon to europium, and included NLTE corrections for 15 elements from carbon to barium that we calculated using pySME and pre-computed grids of departure coefficients. All targets exhibit ‘saturated’ depletion patterns, which we characterised using two-piece linear fits defined by three parameters: initial metallicity ([M/H]$_0$), turn-off temperature ($T_\textrm{turn-off}$), and depletion scale ($\nabla_\textrm{ 100 K}$). Among several findings, we highlight the bimodal distribution of $T_\textrm{turn-off}$ in faint disc targets, which allows classification into two subgroups analogous to full discs with continuous, optically thick dust ($T_\textrm{turn-off} \gt 1 100$ K), and transition discs with inner clearing ($T_\textrm{turn-off} \lt 1 100$ K). Our results imply that faint disc targets likely represent the final stages of disc dissipation, highlighting the diversity of depletion profiles, the complexity of disc-binary interactions, and the need to understand the rarity and evolution of faint disc systems.
This article is the publication of the first bilingual inscription from Hatra, combining Greek with Hatran Aramaic. It is known only from a slide in the archives of the Italian Archaeological Mission to Hatra and, as the first bilingual document from the city itself, it deserves special attention from a multidisciplinary perspective. The inscription is discussed here in its wider context, first with regard to what it can contribute to our understanding of codeswitching between Greek and Aramaic, at Hatra itself and within the wider Near East, and second concerning our knowledge of the development of the city’s local religious life. It is argued that the new inscription casts light on the way in which the goddess ʾAllāt, under influence of the royal house, came to join the Sun god Šmeš (Šamaš) at the heart of Hatrene religion.
We implemented an electronic health record-integrated order set to standardize direct antibiotic challenges for patients with reported antibiotic allergies across nine healthcare facilities. In the first year, 104 patients were challenged (79% oral; 39% two-step). Embedded antibiotic selection, dosage, monitoring parameters, reaction guidance, and rescue medications facilitated uptake by hospitalists and subspecialists.
This study examines the enablers of progress towards net-zero emissions in emerging economies, focusing on the roles of renewable energy integration and energy policy support. Using structural equation modelling on survey data from 935 diverse respondents across India, the study finds that both renewable energy integration and energy policy support have significant positive impacts on net-zero progress. The analysis reveals two key mediating pathways: first, technology adoption and innovation mediate between renewable energy integration and net-zero progress; second, community awareness and participation mediate between energy policy support and net-zero progress. Economic and infrastructure constraints moderate the relationship between energy policy support and net-zero progress. Importance-performance map analysis indicates that while renewable energy, policy support and economic factors are highly important, their effectiveness may be limited by infrastructural and governance challenges. The findings suggest that policymakers should adopt a holistic approach that simultaneously addresses technological, social, economic and institutional dimensions. This study contributes to the net-zero transition literature by developing and validating an integrated model that incorporates technical, social, policy and institutional aspects. Limitations include the cross-sectional nature and single-country focus, suggesting opportunities for future longitudinal and cross-country studies.
Why do incumbent governments carry out harsher repression against some opposition groups than others? Drawing on research on the coalitional nature of revolutions, we contend that governments target repression at segments of the challenger group they perceive as most threatening in order to fragment the challenger coalition. We illustrate this argument by analyzing protest repression during the 2011 Syrian uprising. We find that protestors in majority-Kurdish towns in Syria’s northeast region were significantly less likely to face lethal repression than those in nearby Sunni Arab towns protesting at the same rate. Qualitative evidence from interviews and the Arabic-language secondary literature demonstrate that the Syrian regime shaped its strategy of repression around diverting Kurdish protests from the regime-focused demands of the revolution, thereby separating Kurds from the primarily Sunni Arab opposition. These findings have implications for how ethnic and other identities can be used by incumbents and how incumbent regimes communicate with their populations through the selective deployment of violence.
Existing research analyzes government-recognized Indigenous autonomy as a late twentieth-century phenomenon. Yet even in the unlikely case of nineteenth-century Latin America, where central states systematically targeted Indigenous groups for exploitation, discrimination, and assimilation, governments sometimes adopted policies to recognize Indigenous communal landholding and self-government rights. This paper explores when and why this surprising recognition of Indigenous autonomy occurred. It argues that incumbents were most likely to recognize autonomy when (1) they viewed Indigenous leaders as valuable allies and (2) rural elites were sufficiently weak and could not block government policies they disliked. The former condition incentivized incumbents to recognize autonomy, while the latter gave them the capacity to do so. I test this argument using within-case comparisons across several nineteenth and early twentieth-century cases, which include Guatemala, El Salvador, Ecuador, Bolivia, Peru, and Mexico. The findings offer important insights into historical autonomy and the more recent expansion of Indigenous rights in Latin America.
Coccidia (Apicomplexa) may have a devastating effect on captive reptiles, particularly chameleons and bearded dragons (Pogona vitticeps). This study investigated the potential of three common feeder insects – the Argentine cockroach (Blaptica dubia), the banana cricket (Gryllus assimilis) and the superworm larva (Zophobas morio) – to act as passive vectors for coccidian oocysts, specifically Isospora amphiboluri and Choleoeimeria pogonae, common enteric parasites of captive bearded dragons. Faecal samples from experimentally infected bearded dragons were fed to the insects to assess the passage of viable oocysts through their digestive tracts. Gryllus assimilis exhibited the highest passage rates for both coccidia, followed by B. dubia; Z. morio showed the lowest rates. However, only G. assimilis passed both I. amphiboluri and C. pogonae at a significantly higher rate than Z. morio. These findings suggest that feeder insects, particularly crickets, can act as mechanical vectors for coccidia, highlighting the importance of strict hygiene protocols in reptile keeping minimizing the risk of parasite transmission.
Normal modal logics extending the logic $\mathsf {K4.3}$ of linear transitive frames are known to lack the Craig interpolation property (CIP), except some logics of bounded depth such as $\mathsf {S5}$. We turn this ‘negative’ fact into a research question and pursue a non-uniform approach to Craig interpolation by investigating the following interpolant existence problem: decide whether there exists a Craig interpolant between two given formulas in any fixed logic above $\mathsf {K4.3}$. Using a bisimulation-based characterisation of interpolant existence for descriptive frames, we show that this problem is decidable and coNP-complete for all finitely axiomatisable normal modal logics containing $\mathsf {K4.3}$. It is thus not harder than entailment in these logics, which is in sharp contrast to other recent non-uniform interpolation results. We also extend our approach to Priorean temporal logics (with both past and future modalities) over the standard time flows—the integers, rationals, reals, and finite strict linear orders—none of which is blessed with the CIP.
We study the transfer of (co)silting objects in derived categories of module categories via the extension functors induced by a morphism of commutative rings. It is proved that the extension functors preserve (co)silting objects of (co)finite type. In many cases the bounded silting property descends along faithfully flat ring extensions. In particular, the notion of bounded silting complex is Zariski local.