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The multihit–one target model induces a stochastic ordering of cell survival with respect to the cell sensitivity characteristics. This property can be used for a description of cell killing effects in heterogeneous populations of cells on the basis of randomized versions of the model. In such versions, either the critical number of lesions or the mean number of hits per unit dose (sensitivity), or both, are assumed to be random. We give some new results specifying conditions under which the randomized multihit models are identifiable, with a focus on the following cases: (1) the critical number of radiation-induced lesions, m, is random; (2) the sensitivity parameter, x, is random given m is known or otherwise; (3) x and m form a pair of independent random variables.
For (marked) Poisson point processes we give, for increasing events, a new proof of the analog of the BK inequality. In contrast to other proofs, which use weak-convergence arguments, our proof is ‘direct' and requires no extra topological conditions on the events. Apart from some well-known properties of Poisson point processes, the proof is self-contained.
We derive multivariate Sobel–Uppuluri–Galambos-type lower bounds for the probability that at least a1 and at least a2, and for the probability that exactly a1 and a2, out of n and N events, occur. The lower bound presented here reduces to a sharper bound than that of Galambos and Lee (1992). Our approach is by way of indicator functions and bivariate binomial moments. A new concept, marginal Bonferroni summation, is introduced in this paper.
We investigate the behaviour of P(R ≧ r) and P(R ≦ −r) as r → ∞for the random variable where is an independent, identically distributed sequence with P(− 1 ≦ M ≦ 1) = 1. Random variables of this type appear in insurance mathematics, as solutions of stochastic difference equations, in the analysis of probabilistic algorithms and elsewhere. Exponential and Poissonian tail behaviour can arise.
We derive upper bounds for the total variation distance, d, between the distributions of two random sums of non-negative integer-valued random variables. The main results are then applied to some important random sums, including cluster binomial and cluster multinomial distributions, to obtain bounds on approximating them to suitable Poisson or compound Poisson distributions. These bounds are generally better than the known results on Poisson and compound Poisson approximations. We also obtain a lower bound for d and illustrate it with an example.
In this paper we investigate operators that map one or more probability distributions on the positive real line into another via their Laplace–Stieltjes transforms. Our goal is to make it easier to construct new transforms by manipulating known transforms. We envision the results here assisting modelling in conjunction with numerical transform inversion software. We primarily focus on operators related to infinitely divisible distributions and Lévy processes, drawing upon Feller (1971). We give many concrete examples of infinitely divisible distributions. We consider a cumulant-moment-transfer operator that allows us to relate the cumulants of one distribution to the moments of another. We consider a power-mixture operator corresponding to an independently stopped Lévy process. The special case of exponential power mixtures is a continuous analog of geometric random sums. We introduce a further special case which is remarkably tractable, exponential mixtures of inverse Gaussian distributions (EMIGs). EMIGs arise naturally as approximations for busy periods in queues. We show that the steady-state waiting time in an M/G/1 queue is the difference of two EMIGs when the service-time distribution is an EMIG. We consider several transforms related to first-passage times, e.g. for the M/M/1 queue, reflected Brownian motion and Lévy processes. Some of the associated probability density functions involve Bessel functions and theta functions. We describe properties of the operators, including how they transform moments.
In the paper we first show how to convert a generalized Bonferroni-type inequality into an estimation for the generating function of the number of occurring events, then we give estimates for the deviation of two discrete probability distributions in terms of the maximum distance between their generating functions over the interval [0, 1].
Intersymbol and cochannel interference in a communications channel can often be modelled as the sum of an infinite series of random variables with weights which decay fairly rapidly. Frequently, this yields a random variable which is singular but non-atomic. The Hausdorff dimension of the distribution is estimated and methods for calculating expectations are studied. A connection is observed between the dimension and the complexity of the calculation of an expectation.
In this paper we establish a characterization theorem for a general class of life-testing models based on a relationship between conditional expectation and the failure rate function. As a simple application of the theorem, we characterize the gamma, Weibull, and Gompertz distributions, since they have many probabilistic and statistical properties useful in both biometry and engineering reliability.
We study certain stochastic processes arising in probabilistic modelling. We discuss the limit behavior of these processes and estimate the rate of convergence to the limit.
The concept of max-infinite divisibility is viewed as a positive dependence concept. It is shown that every max-infinitely divisible distribution function is a multivariate totally positive function of order 2 (MTP2). Inequalities are derived, with emphasis on exchangeable distributions. Applications and examples are given throughout the paper.
In this short note, we present a simple characterization of the increasing convex ordering on the set of probability distributions on ℝ. We show its usefulness by providing a very short proof of a comparison result for M/GI/1 queues due to Daley and Rolski, and obtained by completely different means.
The long-tailed Luria–Delbrück distribution arises in connection with the ‘random mutation’ hypothesis (whereas the ‘directed adaptation' hypothesis is thought to give a Poisson distribution). At time t the distribution depends on the parameter m = gNt/(a + g) where Nt is the current population size and g/(a + g) is the relative mutation rate (assumed constant). The paper identifies three models for the distribution in the existing literature and gives a fourth model. Ma et al. (1992) recently proved that there is a remarkably simple recursion relation for the Luria–Delbrück probabilities pn and found that asymptotically pn ≈ c/n2; their numerical studies suggested that c = 1 when the parameter m is unity. Cairns et al. (1988) had previously argued and shown numerically that Pn = Σj ≧ n Pj ≈ m/n. Here we prove that n(n + 1)pn < m(1 + 11m/30) for n = 1, 2, ···, and hence prove that as n becomes large n(n + 1)pn, ≈ m; the result mPn ≈ m follows immediately.
There is a well-known connection between the asymptotic behaviour of the tail of the distribution of the increasing ladder height and the integrated tail of the step distribution of a random walk which either drifts to –∞, or oscillates and whose decreasing ladder height has finite mean. We establish a similar connection in a local sense; this means that in the lattice case we link the asymptotic behaviours of the mass function of the ladder height distribution and of the tail of the step distribution. We deduce the asymptotic behaviour of the mass function of the maximum of the walk, when this is finite, and also treat the non-lattice case.
Recently defined classes of life distributions are considered, and some relationships among them are proposed. The life distribution H of a device subject to shocks occurring randomly according to a Poisson process is also considered, and sufficient conditions for H to belong to these classes are discussed.
Consider a workstation with one server, performing jobs with a service time, Y, having distribution function, G(t). Assume that the station is unreliable, in that it occasionally breaks down. The station is instantaneously repaired, and the server restarts the uncompleted job from the beginning. Let T denote the time it takes to complete each job. If G(t) is exponential with parameter A, then because of the lack-of-memory property of the exponential, P (T > t) = Ḡ(t) =exp(−γt), irrespective of when and how the failures occur. This property also characterizes the exponential distribution.
We consider two weaker partial orderings among non-negative random variables. We derive some characterizations of the equivalence of two life distributions under the weaker orderings. These results lead to the characterizations of the equality of two non-negative random vectors in distributions by moments of extremes and sample mean. As the application of these results, we get various characterizations of the exponential distribution among HNBUE and HNWUE life distribution classes. The main results of Bhattacharjee and Sethuraman (1990), and Basu and Kirmani (1986) are special cases of these more general results.
Consider the total service time of a job on an unreliable server under preemptive-repeat-different and preemptive-resume service disciplines. With identical initial conditions, for both cases, we notice that the distributions of the total service time under these two disciplines coincide, when the original service time (without interruptions due to server failures) is exponential and independent of the server reliability. We show that this fact under varying server reliability is a characterization of the exponential distribution. Further we show, under the same initial conditions, that the coincidence of the mean values also leads to the same characterization.
An observer watches one of a set of Poisson streams. He may switch from one stream to another instantaneously. If an arrival occurs in a stream while the observer is watching another stream, he does not see the arrival. The experiment terminates when the observer sees an arrival. We derive a formula which states essentially that the expected total time that the observer watches a stream is equal to the probability that he sees the arrival in this stream divided by the intensity of the stream. This formula is valid independently of the observation policy. We also discuss applications of this formula.
Suppose that a device is subjected to shocks governed by a counting process N = {N(t), t ≧0}. The probability that the device survives beyond time t is then H̄(t)=Σk=0∞Q̄ℙ[N(t)=k], where Q̄k is the probability of surviving k shocks. It is known that H is NBU if the interarrivals Uk, ∊ ℕ+, are independent and NBU, and Q̄k+j ≦ Q̄k· Q̄j holds whenever k, j ∊ ℕ. Similar results hold for the classes of the NBUE and HNBUE distributions. We show that some other ageing classes have similar properties.