Demographic changes in rates of living alone, migration, and having no living partner, spouse, or children are leaving more older adults without the typical uncompensated familial and non-familial care partners that are the backbone of long-term care provision. We aimed to understand the precarities and outcomes specifically experienced by older adults without care partners to inform future intervention development. Using the Joanna Briggs Institute guidelines and PRISMA-ScR protocol, we conducted a scoping review of nine databases to map the current peer-reviewed evidence regarding these indivdiduals’ precarities, outcomes, and interventions using the Health Equity Promotion Model (HEPM) as our guiding framework. Our comprehensive search strategy resulted in 5,100 unique articles, 33 of which met our inclusion criteria. Three independent reviewers screened and extracted data, and the first author used deductive content analysis with the pre-specified HEPM framework. Fifteen studies reported precarities related to environmental/structural forces, and psychological, social, behavioral, and biological processes. Twenty-four studies reported adverse health and well-being outcomes with more focus on health than well-being outcomes (19 versus 8). Four studies tested interventions, and reported environmental/structural, social, and behavioral processes and health and well-being outcomes. Only 13 of the 33 reviewed studies set out to explicitly study older adults without care partners, and no studies focused on marginalized sub-groups. This scoping review highlights our lack of understanding of older adults without care partners’ distinctive precarities and outcomes, and the vital research needed to develop and test interventions that effectively address their unique needs.