Panax L., renowned as ginseng genus, is a famous medicinal group of family Araliaceae. Within this genus, the taxa of Panax bipinnatifidus complex are mainly distributed in Himalayas and Hengduan Mountain areas. Due to the complex evolutionary history and short-term rapid radiation, the relationships among species within the complex have not been clearly resolved, and the taxa identification is difficult due to the intermediate morphological traits. This study aimed to use the available restriction-site associated DNA sequence data from 29 individuals of P. bipinnatifidus complex to mine high-polymorphic simple sequence repeat (SSR) markers, with the goal of evaluating their utility in taxa identification. Eleven polymorphic SSR loci were ultimately selected and validated through polymerase chain reactions amplifying across 63 individuals of P. bipinnatifidus complex and 13 individuals of three outgroup species. The subsequent genetic diversity analysis uncovered 76 alleles in total, ranging from 5 to 15 per locus. Observed heterozygosity spanned 0.241–0.512, while expected heterozygosity ranged between 0.345 and 0.644. The genetic kinship analysis revealed a sister relationship between Panax zingiberensis and Panax vietnamensis. The analysis result also supported the classification of samples from Hunan and Hubei provinces into a single genetic unit within the P. bipinnatifidus complex. These newly developed SSR markers will facilitate the identification of wild ginseng plants.

The paper builds a parsimonious US business cycle SVARMA model, establishing identification conditions for independent monetary shocks. The SVARMA model, utilizing Divisia M3 and Divisia M4, is compared to the simple sum M2. The monetary rule with Divisia M3 yields theoretically consistent results marked by the absence of the usual price and liquidity puzzles. As the Federal Reserve (Fed) took a more hawkish approach to curb inflation, significant increases in US interest rates and declines in monetary aggregates were largely influenced by the Fed’s reaction function, which incorporates the Divisia M3 monetary rule. Findings emphasize the monetary impact on the business cycle, highlighting the significance of Divisia monetary aggregates. Historical and variance decompositions reveal diverse, dynamic effects of monetary shocks on macroeconomic variables. The SVARMA model with Divisia M3 and M4 demonstrates superior performance over simple sum M2 in capturing the time path of monetary shocks.

In the present work, the asymptotic-numerical method is applied in conjunction with the Ritz method as a powerful mean for analysing the post-buckling response of panels with variable stiffness skin and curvilinear stringers. Main advantage of the proposed approach is the reduced computational time. The Ritz method guarantees an excellent ratio between accuracy and required degrees of freedom; the asymptotic-numerical method requires just one matrix inversion throughout the solution process. Moreover, the complete analytical representation of the non-linear equilibrium path is obtained, as opposed to the point-by-point representation of predictor-corrector algorithms. Several test cases are presented and compared with standard Newton-Raphson computations and commercial finite element simulations. The results show noticeable saving of computational time. For the test cases investigated, the asymptotic-numerical method requires about one third of the time required by a standard Newton-Raphson routine. These results demonstrate that the combination between Ritz and the asymptotic-numerical method is an excellent strategy for investigating the post-buckling response of innovative curvilinearly stiffened panels.

This article studies how sudden changes in bank credit supply impact economic activity. I identify shocks to bank credit supply based on firms’ aggregate debt composition. I use a model where firms fund production with bonds and loans. In the model, bank shocks are the only type of shock that imply opposite movements in the two types of debt as firms adjust their debt composition to new credit conditions. Bank shocks account for a third of output fluctuations and are predictive of the bond spread.

Microcosmus squamiger, an ascidian with high invasion potential, is recorded for the first time in the Brazilian western Atlantic, between Rio de Janeiro and Espírito Santo. The species was found near ports and marinas, and its introduction may have been favoured by intense nautical activity and climatic events such as La Niña. Coexistence with Microcosmus exasperatus, a morphologically similar species, was observed in all localities where M. squamiger was recorded. This discovery implies that a more rigorous process of species identification is necessary during monitoring activities, given that both species can be easily confused (only the syphon spinules differentiate them) and M. exasperatus is widely distributed with collection records dating back more than half a century on the Brazilian coast. The preference of M. squamiger for colder waters suggests that researchers in the Southeast and South Brazil, Uruguay, and Argentina should closely monitor the arrival and possible environmental impacts of this species. The identification of M. squamiger in locations close to bivalve mariculture areas in Rio de Janeiro raises concern, as the species has the potential to compete with bivalves. This study highlights the importance of continuing to monitor the potential spread and the implications of the introduction of M. squamiger into Brazilian waters, as well as its relationship with M. exasperatus, a species already established in this same region.

There are increasing calls for coverage of medicine during the Holocaust in medical school curricula. This article describes outcomes from a Holocaust and medicine educational program featuring a study trip to Poland, which focused on physician complicity during the Holocaust, as well as moral courage in health professionals who demonstrated various forms of resistance in the ghettos and concentration camps. The trip included tours of key sites in Krakow, Oswiecim, and the Auschwitz-Birkenau concentration camps, as well as meeting with survivors, lectures, reflective writings, and discussions. In-depth interviews and reflective writings were qualitatively analyzed. Resulting themes centered on greater understanding of the relationship between bioethics and the Holocaust, recognizing the need for moral courage and social awareness, deeper appreciation for the historical roles played by dehumanization and medical power and their contemporary manifestations, and the power of presence and experiential learning for bioethics education and professional identity formation. These findings evidence the significant impact of the experience and suggest broader adoption of pedagogies that include place-based and experiential learning coupled with critical reflection can amplify the impact of bioethics and humanism education as well as the process of professional identity formation of medical students.

Effluent waste generated from the intensive production of vannamei shrimp is known to play an essential role in increasing phytoplankton abundance and the alteration of environmental quality. This alteration is characterized by the presence of various organic compounds and their derivatives. The northern coastal area of Bangka Island represents a region in Indonesia that has witnessed significant growth and development as a vannamei shrimp cultivation zone. Therefore, this study aims to evaluate phytoplankton abundance and environmental quality in the waste of shrimp ponds in the northern coastal area of Bangka Island. The investigation procedures were carried out in four specific locations within this area, namely BL1, BL2, BL3, and BL4. The results showed the presence of five–six distinct phytoplankton groups, including a total of 11–18 genera, within the effluent discharge from these ponds. The highest abundance of phytoplankton was recorded at BL3, with a value of 2,418,375 cells ml−1. The phytoplankton groups identified at all locations included Chlorophyta, Cyanophyta, Chryptophyta, Bacillariophyta, and Pyrrophyta. Euglenophyta was found at BL1 and BL3 but was not observed at BL2 and BL4. Furthermore, the most abundant group found in this study was Chlorophyta. The genera Nanochloropsis, Chlorella, Microcystis, and Nitzschia were consistently found in all the surveyed ponds. The calculation results showed that all locations had a moderate level of diversity, high evenness, and the absence of dominance. Based on the findings of principal component analysis, there was a commonality in parameters that exerted a strong influence on phytoplankton abundance, including nitrate, orthophosphate, and magnesium.

This paper examines the question of reparation for non-recent institutional child sexual abuse in England and Wales and Australia in the light of independent inquiries which reported in 2022 (England and Wales) and 2017 (Australia). Both inquiries recommended the introduction of state-based redress schemes that would exist alongside private law. While the new UK government considers how to proceed, Australia has established a national redress scheme, there have been changes to private law and new legislation reforming tort law and removing procedural obstacles such as limitation. In evaluating the Australian reforms and the case for change in English law, this paper examines the different roles state-based redress and private law compensation play in responding to the harm suffered by victims and survivors of sexual abuse. It argues that there are urgent lessons that the UK government should learn from the Australian experience in establishing a redress scheme and that while legislative change to substantive private law has proven less than successfull in Australia, legislation on limitation periods and suing unincorporated associations has assisted plaintiffs. Finally there are lessons that private law can learn from state-based redress schemes in seeking to provide remedies that meet the distinctive needs of victims and survivors of child sexual abuse.

I argue that more and less are always determinatives, contrary to the categorization in The Cambridge Grammar of the English Language (CGEL), which treats them as adverbs in analytic comparatives. Evidence is presented of contrasts between more/less and much/little in various contexts, challenging CGEL’s empirical claim that such contrasts never occur in analytic comparatives. The observed distributional patterns can largely be explained by the semantics of more/-er and much without positing a category distinction: more/-er establishes a salient scale-internal reference point, while much requires such a point to already be present. Furthermore, mere distributional differences should not be relied upon for category assignment, following arguments by Payne , Huddleston & Pullum (2010). For these reasons, analyzing more and less as adverbs in any context is unnecessary and unparsimonious. The determinative analysis can account for all the relevant data. Beyond the narrow point about categorization, the paper illustrates the contributions of semantic, pragmatic, and distributional evidence in resolving category assignment.

Classic Maya history was rife with shifting political coalitions and disputes with the key antagonists, Tikal and the Kaan regime, at the center. Understanding how power dynamics and political shifts were experienced among subordinate polities is best viewed from multiple perspectives. We employ elements of Graeber and Sahlins' (2017) stranger-king model, focusing on exogamous marriage practices in relation to two Snake Queens ruling at Waka’. They served as direct links between the Kaan regime and the subordinate Wak polity. We focus on the political and diplomatic nature of their roles in crafting Waka's place in the overarching narratives of alliance and conquest during the sixth through the early part of the eighth centuries. The pairing of archaeological and textual data surrounding Ix Ikoom in the sixth century and Lady K'abel during the seventh century permit interrogation of women's prominence with respect to Kaan regime-building strategies during these centuries.

Psychopathology is intergenerationally transmitted through both genetic and environmental mechanisms via heterotypic (cross-domain), homotypic (domain-specific), and general (e.g., “p-factor”) pathways. The current study leveraged an adopted-at-birth design, the Early Growth and Development Study (57% male; 55.6% White, 19.3% Multiracial, 13% Black/African American, 10.9% Hispanic/Latine) to explore the relative influence of these pathways via associations between adoptive caregiver psychopathology (indexing potential environmental transmission) and birth parent psychopathology (indexing genetic transmission) with adolescent internalizing and externalizing symptoms. We included composite measures of adoptive and birth parent internalizing, externalizing, and substance use domains, and a general “p-factor.” Age 11 adolescent internalizing and externalizing symptom scores were the average of adoptive parent reports on the Child Behavior Checklist (n = 407). Examining domains independently without addressing comorbidity can lead to incorrect interpretations of transmission mode. Therefore, we also examined symptom severity (like the “p-factor”) and an orthogonal symptom directionality score to more cleanly disentangle transmission modes. The pattern of correlations was consistent with mostly general transmission in families with youth showing comorbid internalizing and externalizing symptoms, rather than homotypic transmission. Findings more strongly supported potential environmental or evocative mechanisms of intergenerational transmission than genetic transmission mechanisms (though see limitations). Parent-specific effects are discussed.

The game of Cops and Robber is traditionally played on a finite graph. The purpose of this article is to introduce and analyze the game that is played on an arbitrary geodesic space (a compact, path-connected space endowed with intrinsic metric). It is shown that the game played on metric graphs is essentially the same as the discrete game played on abstract graphs and that for every compact geodesic surface there is an integer c such that c cops can win the game against one robber, and c only depends on the genus g of the surface. It is shown that $c=3$ for orientable surfaces of genus $0$ or $1$ and nonorientable surfaces of crosscap number $1$ or $2$ (with any number of boundary components) and that $c=O(g)$ and that $c=\Omega (\sqrt {g})$ when the genus g is larger. The main motivation for discussing this game is to view the cop number (the minimum number of cops needed to catch the robber) as a new geometric invariant describing how complex is the geodesic space.

I investigate the effects of trade on labor coercion under the dual-coercive institutions of slavery and state coercion. Employing novel data from Egypt, I document that the cotton boom in 1861–1865 increased both imported slaveholdings of the rural middle class and state coercion of local workers by the elite. As state coercion reduced wage employment, it reinforced the demand for slaves among the rural middle class. While the abolition of slavery in 1877 increased wages, it did not affect state coercion or wage employment. I discuss the political effects of the abolition as a potential explanation for these findings.

“The barbarism of the [U.S.] South, while destroying itself, [appeared] in the providence of God to be working out the regeneration of Egypt.”

North American Review 98, no. 203 (1864, p. 483), quoted in Earle (1926)

In the wake of the establishment of the Portuguese in the region, slavery was fundamentally constitutive of early modern society on the west coast of India. While indigenous hierarchies and existing systems of slavery shaped Portuguese slavery, over time, indigenous society too was transformed by the extensive reliance on enslaved labor facilitated by European trafficking networks. Centering slavery in the study of South Asian history underscores the importance of considering the difference between elite projects of enforcing boundaries, both spatial and social, and the ways in which enslaved people negotiated these projects. Thus, instead of taking for granted the classificatory labels of race, caste, and blackness imposed upon enslaved peoples by elite institutions, a social history of slavery elucidates instead the evolution of these mechanisms for policing identity, and the centrality of the expropriation of labor in identity formation.