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We obtain a new interpretation of the cohomological Hall algebra $\mathcal {H}_Q$ of a symmetric quiver Q in the context of the theory of vertex algebras. Namely, we show that the graded dual of $\mathcal {H}_Q$ is naturally identified with the underlying vector space of the principal free vertex algebra associated to the Euler form of Q. Properties of that vertex algebra are shown to account for the key results about $\mathcal {H}_Q$. In particular, it has a natural structure of a vertex bialgebra, leading to a new interpretation of the product of $\mathcal {H}_Q$. Moreover, it is isomorphic to the universal enveloping vertex algebra of a certain vertex Lie algebra, which leads to a new interpretation of Donaldson–Thomas invariants of Q (and, in particular, re-proves their positivity). Finally, it is possible to use that vertex algebra to give a new interpretation of CoHA modules made of cohomologies of non-commutative Hilbert schemes.
We use three-dimensional direct numerical simulations of homogeneous isotropic turbulence in a cubic domain to investigate the dynamics of heavy, chiral, finite-size inertial particles and their effects on the flow. Using an immersed-boundary method and a complex collision model, four-way coupled simulations have been performed, and the effects of particle-to-fluid density ratio, turbulence strength and particle volume fraction have been analysed. We find that freely falling particles on the one hand add energy to the turbulent flow but, on the other hand, they also enhance the flow dissipation: depending on the combination of flow parameters, the former or the latter mechanism prevails, thus yielding enhanced or weakened turbulence. Furthermore, particle chirality entails a preferential angular velocity which induces a net vorticity in the fluid phase. As turbulence strengthens, the energy introduced by the falling particles becomes less relevant and stronger velocity fluctuations alter the solid phase dynamics, making the effect of chirality irrelevant for the large-scale features of the flow. Moreover, comparing the time history of collision events for chiral particles and spheres (at the same volume fraction) suggests that the former tend to entangle, in contrast to the latter which rebound impulsively.
The importance of habitat-forming species, particularly cold-water corals like Dendrophyllia ramea, cannot be overstated as they provide crucial physical structures that offer shelter, food, and breeding habitat for a range of other species. We studied the spatial distribution and abundance of D. ramea, its associated species and the impact of human activities in a population of the Herradura, Granada in the western Mediterranean. Video transects were conducted at different depths, and epibiont samples were collected to describe the coral assemblage and the diversity of associated organisms. Dendrophyllia ramea presented high abundances at an unusually shallow depth in the Mediterranean, ranging from 30 to 48 m, despite typically being found between 50 and 500 m, with recordings indicating occurrences as deep as 1000 m, and hosting a high number of epibionts and macro-benthic organisms associated with coral reefs. Bryozoans showed a close relationship with D. ramea as they are important components of both the reef and the epibiont community. This study identified 63 new species and 15 new genera associated with cold-water corals. This study showed the importance of D. ramea as a nursery site, even for other habitat-forming species. The major threat to this community is human activity (fishing, littering and free anchoring), with the most abundant types of waste being rubber, glass/ceramics, and plastic polymers, and many fishing lines and nets damaging the corals. Overall, this study emphasises the urgent need to protect cold-water corals and their associated species and reduce the impact of human activities on marine ecosystems.
We characterize the fractional Dehn twist coefficient (FDTC) on the n-stranded braid group as the unique homogeneous quasimorphism to $\mathbb {R}$ of defect at most 1 that equals 1 on the positive full twist and vanishes on the $(n-1)$-stranded braid subgroup. In a different direction, we establish that the slice-Bennequin inequality holds with the FDTC in place of the writhe. In other words, we establish an affine linear lower bound for the smooth slice genus of the closure of a braid in terms of the braid’s FDTC. We also discuss connections between these two seemingly unrelated results. In the appendix, we provide a unifying framework for the slice-Bennequin inequality and its counterpart for the FDTC.
We prove a general formula that relates the parity of the Langlands parameter of a conjugate self-dual discrete series representation of $\operatorname { {GL}}_n$ to the parity of its Jacquet-Langlands image. It gives a generalization of a partial result by Mieda concerning the case of invariant $1/n$ and supercuspidal representations. It also gives a variation of the result on the self-dual case by Prasad and Ramakrishnan.
This study contributes to an emerging body of research that combines new mobilities and gerontological perspectives. Most previous studies on older adults’ mobilities have analysed data collected at a single point in time and there is a need for studies that explore the meanings of movement and non-movement over time, especially in relation to unexpected life events. This work explores the meanings of older adults’ abruptly changing everyday (im)mobilities before and during the Covid-19 pandemic. It draws from qualitative interviews conducted with 11 older adults in a Finnish suburb in autumn 2019 and spring 2020, and focuses on grocery shopping, which most of the participants did themselves before the pandemic, but not during it. The findings provide insight into how meanings of everyday (im)mobilities are formed as older individuals (re)negotiate their relationships with their changing places of ageing. The participants’ views of their disrupted everyday mobilities were shaped by active person–place engagements. On one hand, the findings highlight that individuals are not at the mercy of their circumstances; they possess agency that can enable maintaining a sense of self and independence even in restricted mobility situations. On the other hand, the findings reveal relationalities that explain why sudden mobility loss often leads to diminished wellbeing. The relational nature of the meanings of (im)mobility implies that there is no one-size-fits-all approach to supporting older adults who face mobility difficulties while ageing in their homes. It is crucial to recognise the diversity of older adults and to support their individual lifestyles.
Sea turtle populations have significantly declined in recent years due to anthropogenic causes. Historical stranding records in the Canary Islands archipelago (Spain) reveal a high frequency of Caretta caretta and Chelonia mydas strandings. Our study aims to comprehensively characterize and explore these stranding records. Additionally, we have investigated the interactions between sea turtles and the island's professional fishers, seeking insights from small-scale artisanal fishers to understand the current state of sea turtle populations. The results have shown that Tenerife stands out with the highest number of sea turtle strandings, recording 1875 strandings over a span of 23 years. The primary cause of sea turtle stranding's is the interaction with fishing gear, specifically nets and hooks. Moreover, our research has highlighted the need for improved knowledge and training on how to handle stranded sea turtles within the fishing sector. Consequently, raising awareness and implementing conservation plans for sea turtle populations in Tenerife is of outmost importance in addressing and improving the current situation.
In 2015, a new accelerator mass spectrometry facility (AMS), the ECHoMICADAS (Environnement, Climat, Homme, MIni CArbon DAting System), was installed in the Laboratoire des Sciences du Climat et de l’Environnement (LSCE). Equipped with a hybrid source, it allows the analysis of solid or gas samples for 14C measurement. Here, we summarize the equipment surrounding the Gas Interface System (GIS), namely the elemental analyzer (EA), the carbonate handling system (CHS2) and the ampoule cracker. We describe our model of sample contamination, taking into account the cross and the constant contaminations, and then describe how these contaminations were handled in the data processing. Both contaminant corrections are applied before the phases of blank subtraction and standard normalization, making it possible to use the standard, blank and sample ratios without contaminant during these phases. We finally present our results on normalization standards (N=118), blanks (N=125) and reference materials (N=117) for different measurement protocols and for sample masses between 3 and 300 µgC.
Yakushima is a small, mountainous island off southern Kyushu, Japan. Its proximity to active volcanos and subduction zones leaves Yakushima vulnerable to large megathrust earthquakes and tsunamis, in addition to powerful typhoons and storm surges. These hazardous events deposit beach boulders: large rocks moved above sea-level by powerful waves. By radiocarbon dating the fossilized coral within these boulders, one can derive age estimates of the hazard events. Reliably estimating the magnitude and timing of geological events in the historical record is vital for future hazard prediction and mitigation. In this study, we estimated the deposition age of ten boulders on the north coast of Yakushima to infer potential paleo tsunamis and storm surges. We found that large wave events have occurred frequently throughout the Holocene. Based on the boulders’ ages, we identified four potential deposition events at 1986–2692 cal yr BP, 3522–4075 cal yr BP, 4773–5232 cal yr BP, and 6187–6638 cal yr BP. These deposits are likely a result of storm surges, or tsunamis from nearby volcanic activity or subduction earthquakes. Another set of boulders dated to 5125–5738 cal yr BP were likely exposed due to a decline in sea-level following the Holocene high sea-level stand. Further modelling could determine the wave height necessary to move the boulders and distinguish between storm and tsunami deposits. This is especially pertinent given the high frequency of coastal geohazards, and the likelihood of similar hazards impacting southeast Japan in the future.
While factors such as age and education have been associated with persistent differences in functional cognitive decline, they do not fully explain observed variations particularly those between different racial/ethnic and sex groups. The aim of this study was to explore the association between allostatic load (AL) and cognition in a racially diverse cohort of young adults.
Methods:
Utilizing Wave V of the National Longitudinal Study of Adolescent to Adult Health – a nationally representative, longitudinal survey of adults aged 34–44, this study utilized primary data from 10 immune, cardiovascular, and metabolic biomarkers to derive an AL Index. Cognition was previously recorded through word and number recall scores. Regression analysis evaluated the association between cognitive recall, AL, age, sex, and race/ethnicity.
Results:
Regression results indicated statistically higher AL scores among Blacks (IRR = 1.09, CI = 1.01, 1.19) compared to Whites and lower AL score among females compared to males (IRR = 0.76, CI = 0.72, 0.81). At zero AL, Blacks (IRR = 1.2399, CI = 1.2398, 1.24) and Other races (IRR = 1.4523, CI = 1.452, 1.4525) had higher recall while Hispanics (IRR = 0.808, CI = 0.8079, 0.8081) had lower recall compared to Whites. Relative to males, females had higher number recall (IRR = 1.1976, CI = 1.1976, 1.1977). However, at higher, positive levels of AL, Blacks (IRR = 0.9554, CI = 0.9553, 0.9554), Other races (IRR = 0.9479, CI = 0.9479, 0.9479) and females (IRR = 0.9655, CI = 0.9655, 0.9655) had significantly lower number recall than Whites and males respectively.
Conclusions:
Race and sex differences were observed in recall at different levels of AL. Findings demonstrate the need for further exploration of cognition in young adults across diverse populations that includes examination of AL.
There is a high prevalence of sleep disturbances among people living with dementia (PLWD) in nursing homes. Reliable and valid measurements are needed to assess these disturbances. The aim of this systematic review was to identify, analyze and synthesize studies of sleep-related measurements to assess sleep disturbances in PLWD.
Methods:
The databases PubMed, CINAHL, and PsycINFO were systematically searched in 2019; the search was updated in March 2024. The inclusion criteria were as follows: participants with dementia or probable dementia in any care setting; and studies that reported at least one of the following aspects: (I) theoretical and conceptual frameworks, (II) user or patient involvement by type of users in measurement development, (III) feasibility and practicability of measurements, and (IV) results of psychometric analyses. The quality of the included studies was evaluated using the COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) criteria and the quality appraisal tool for studies of diagnostic reliability (QAREL) tool.
Results:
A total of 5169 studies were identified; ultimately, 15 studies describing three self-administered measurements, three proxy-administered measurements and two technological measurements were included. No sleep-related measurement showed acceptable psychometric properties in any of the COSMIN domains.
Conclusions:
No measurement without adaptation can be recommended for PLWD in nursing homes. If existing measurements are used in clinical practice, the self-perspective of PLWD should be taken into account. If this is no longer fully possible, proxy-rating perspectives in combination could be an option. Future research on sleep-related measurements should be strictly based on international consensus-based psychometric quality criteria.
Among participants with Alzheimer's disease (AD) we estimated the minimal clinically important difference (MCID) in apathy symptom severity on three scales.
Design:
Retrospective anchor- and distribution-based analyses of change in apathy symptom scores.
Setting:
Apathy in Dementia Methylphenidate Trial (ADMET) and ADMET 2 randomized controlled trials conducted at three and ten clinics specialized in dementia care in United States and Canada, respectively.
Participants:
Two hundred and sixty participants (60 ADMET, 200 ADMET 2) with clinically significant apathy in Alzheimer’s disease.
Measurements:
The Clinical Global Impression of Change in Apathy scale was used as the anchor measure and the MCID on the Neuropsychiatric Inventory – Apathy (NPI-A), Dementia Apathy Interview and Rating (DAIR), and Apathy Evaluation Scale-Informant (AES-I) were estimated with linear mixed models across all study visits. The estimated thresholds were evaluated with performance metrics.
Results:
Among the MCID was a decrease of four points (95% CI: −4.0 to −4.8) on the NPI-A, 0.56 points (95% CI: −0.47 to −0.65) on the DAIR, and three points on the AES-I (95% CI: −0.9 to −5.4). Distribution-based analyses were largely consistent with the anchor-based analyses. The MCID across the three measures showed ∼60% accuracy. Sensitivity analyses found that MMSE scores and apathy severity at baseline influenced the estimated MCID.
Conclusions:
MCIDs for apathy on three scales will help evaluate treatment efficacy at the individual level. However, the modest correspondence between MCID and clinical impression of change suggests the need to consider other scales.
By the second half of the first millennium CE, a substantial body of texts written in Literary Sinitic developed into a shared repertoire of writings throughout Central and East Asia. In no small part, this was the result of the spread of Buddhism, which, in many regions, was adopted in its Sinitic form and relied on Chinese versions of the scriptures. As part of the means to cope with Sinitic Buddhist texts, most states also adopted a range of auxiliary texts, including primers and dictionaries. While modern scholarship has directed substantial attention at the participation of Japan, Korea, and Vietnam in the world of Sinitic texts, it has placed much less emphasis on the western and north-western regions of what is now China. This article attempts to redress the imbalance and demonstrate not only that, at one point, Inner Asian states actively participated in the Sinographic world, but also that they did this through a similar process of adaptation to that documented elsewhere. Primers played a special role in this, in that they had a more immediate connection with the core competency of reading and writing.
We have left antegrade pulmonary blood flow (APBF) at bidirectional cavopulmonary shunt (BCPS) only for high-risk patients. This study evaluates the indication and the outcomes of patients with APBF, compared to those without APBF.
Methods:
Patients with APBF after BCPS were identified among patients who underwent BCPS between 1997 and 2022. Outcomes of patients with and without APBF after BCPS were compared.
Results:
APBF was open in 38 (8.2%) of 461 patients. Median age (7.7 versus 6.3 months, p = 0.55) and weight (5.6 versus 6.1 kg, p = 0.75) at BCPS were similar in both groups. The most frequent indication for APBF was high pulmonary artery pressure (PAP) in 14 patients, followed by hypoxaemia in 10, and hypoplastic left pulmonary artery in 8. The source of APBF was the pulmonary trunk in 10 patients and the aortopulmonary shunt in 28. Median hospital stay after BCPS was longer (22 versus 14 days, p = 0.018) and hospital mortality was higher (10.5 versus 2.1%, p = 0.003) in patients with APBF compared to those without APBF. However, 448 hospital survivors showed similar survival after discharge following BCPS (p = 0.224). Survival after total cavopulmonary connection (TCPC) was similar between the groups (p = 0.753), although patients with APBF were older at TCPC compared to those without (3.9 versus 2.2 years, p = 0.010).
Conclusion:
APBF was left in 8% following BCPS in high-risk patients, mainly due to preoperative high PAP. Hospital survivors after BCPS demonstrated comparable survival in patients with and without APBF. Adding APBF at BCPS might be a useful option for high-risk patients.
In the late 1850s and early 1860s, the idea of building a passage through the Isthmus of Kra in the Malay Peninsula was hotly debated amongst British officials, merchants, and investors. This study finds that the British East India Company's rule over the Straits of Malacca had been a dilemma for itself and British merchants in China. The Second Opium War and the Indian Revolt of 1857 exacerbated the dilemma and pushed some British policymakers and investors to seek an alternative route between India and China. The proposal of the Kra passage was the response and solution to the Malacca dilemma. In historicising the Kra passage proposal and putting it in the context of the British empire's simultaneous crises in Asia in the mid-nineteenth century, the case of the proposed Kra passage reveals the complex relations between different actors within the British empire and the challenges of integrating multiple imperial interests into a British world system
Older adults are identified to have reduced social cognitive performance compared to younger adults. However, few studies have examined age-associations throughout later life to determine whether these reductions continue with advancing age.
Method:
This study assesses cross-sectional associations of emotion perception, cognitive and affective theory of mind (ToM), and emotional empathy in a healthy sample of 157 adults aged 50–89 years (M = 65.31, SD = 9.00, 68% female sex). Emotion perception, cognitive ToM, and affective ToM were measured using The Awareness of Social Inference Test Short Form (TASIT-S), while affective ToM was also measured using Reading the Mind in the Eyes Revised (RME-R). Emotional empathy was measured using the Empathy Quotient.
Results:
Multiple regression analyses, adjusting for multiple comparisons, revealed a moderate negative association between age and emotion perception for all emotions combined, as well as for sad and revolted expressions, but not happy, neutral, anxious, or angry expressions. Age had a negative, moderate association with first-order cognitive, second-order cognitive, and affective ToM measured using TASIT-S, but not RME-R. Age was not significantly associated with emotional empathy.
Conclusions:
This study contributes to the limited understanding of age-related associations of social cognitive performance throughout later life. This knowledge can inform future research examining the clinical utility of including social cognitive measures in neuropsychological screening and diagnostic tools for later-life neurological disorders.