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The concept of a forest transition – a regional shift from deforestation to forest recovery – tends to equate forest area expansion with sustainability, assuming that more forest is good for people and the environment. To promote debate and more just and ecologically sustainable outcomes during this period of intense focus on forests (such as the United Nations’ Decade on Ecological Restoration, the Trillion Trees initiative and at the United Nations’ Climate Change Conferences), we synthesize recent nuanced and integrated research to inform forest management and restoration in the future. Our results reveal nine pitfalls to assuming forest transitions and sustainability are automatically linked. The pitfalls are as follows: (1) fixating on forest quantity instead of quality; (2) masking local diversity with large-scale trends; (3) expecting U-shaped temporal trends of forest change; (4) failing to account for irreversibility; (5) framing categories and concepts as universal/neutral; (6) diverting attention from the simplification of forestlands into single-purpose conservation forests or intensive production lands; (7) neglecting social power transitions and dispossessions; (8) neglecting productivism as the hidden driving force; and (9) ignoring local agency and sentiments. We develop and illustrate these pitfalls with local- and national-level evidence from Southeast Asia and outline forward-looking recommendations for research and policy to address them. Forest transition research that neglects these pitfalls risks legitimizing unsustainable and unjust policies and programmes of forest restoration or tree planting.
In this introduction, I briefly summarize Sophia Moreau's Faces of Inequality. I situate her monograph within two highly contemporary bodies of literature — relational egalitarianism and discrimination theory — to show how it provides important insights for understanding both what it means to treat others as equals in society and how to define wrongful discrimination. Moreau's work on discrimination is of great relevance for philosophers and socio-legal theorists alike as the commentaries from the symposium contributors demonstrate, including Dale Smith, Pablo Gilabert, Andrea Sangiovanni, Daniel Viehoff, Jessica Eisen, Alysia Blackham, and Iyiola Solanke.
Oscillatory flows have become an indispensable tool in microfluidics, inducing inertial effects for displacing and manipulating fluid-borne objects in a reliable, controllable and label-free fashion. However, the quantitative description of such effects has been confined to limit cases and specialized scenarios. Here we develop an analytical formalism yielding the equation of motion of density-mismatched spherical particles in oscillatory background flows, generalizing previous work. Inertial force terms are systematically derived from the geometry of the flow field together with analytically known Stokes number dependences. Supported by independent, first-principles direct numerical simulations, we find that these forces are important even for nearly density-matched objects such as cells or bacteria, enabling their fast displacement and separation. Our formalism thus consistently incorporates particle inertia into the Maxey–Riley equation, and in doing so provides a generalization of Auton's modification to added mass, as well as recovering the description of acoustic radiation forces on particles as a limiting case.
The war in Ukraine raises concerns for potential hazards of radiological and nuclear incidents. Children are particularly vulnerable in these incidents and may need pharmaceutical countermeasures, including antidotes and cytokines. Searches found no published study comparing pediatric indications and dosing among standard references detailing pediatric medications for these incidents. This study addresses this gap by collecting, tabulating, and disseminating this information to healthcare professionals caring for children. Expert consensus chose the following references to compare their pediatric indications and dosing of medical countermeasures for radiation exposure and internal contamination with radioactive materials: Advanced Hazmat Life Support (AHLS) for Radiological Incidents and Terrorism, DailyMed, Internal Contamination Clinical Reference, Medical Aspects of Radiation Incidents, and Medical Management of Radiological Casualties, as well as Micromedex, POISINDEX, and Radiation Emergency Medical Management (REMM). This is the first study comparing pediatric indications and dosing for medical countermeasures among commonly used references for radiological and nuclear incidents.
Cette étude se penche sur la communication du Parti conservateur du Québec (PCQ) sur Facebook et X au cours de l'année précédant l’élection générale québécoise de 2022. Basée sur une analyse de contenu d'un échantillon de 800 messages diffusés sur Facebook et X par le parti et son chef Éric Duhaime, l'analyse relève les éléments populistes des publications de même que les objectifs politiques de sa communication en ligne. L'article démontre comment le parti a utilisé ces plateformes numériques afin de tenter de mobiliser une base d’électeurs en contournant les filtres médiatiques traditionnels et en s'adressant directement aux électeurs afin de tirer profit du contexte médiatique hybride québécois. Deux conclusions découlent de nos analyses. Premièrement, le PCQ semble avoir employé un discours populiste à caractère antiélitiste de manière à exploiter une grogne pandémique présente au Québec. Deuxièmement, le parti a utilisé les fonctions de mobilisations qu'offrent les médias socionumériques afin de constituer une coalition d’électeurs.
A significant proportion of people with clozapine-treated schizophrenia develop ‘checking’ compulsions, a phenomenon yet to be understood.
Aims
To use habit formation models developed in cognitive neuroscience to investigate the dynamic interplay between psychosis, clozapine dose and obsessive–compulsive symptoms (OCS).
Method
Using the anonymised electronic records of a cohort of clozapine-treated patients, including longitudinal assessments of OCS and psychosis, we performed longitudinal multi-level mediation and multi-level moderation analyses to explore associations of psychosis with obsessiveness and excessive checking. Classic bivariate correlation tests were used to assess clozapine load and checking compulsions. The influence of specific genetic variants was tested in a subsample.
Results
A total of 196 clozapine-treated individuals and 459 face-to-face assessments were included. We found significant OCS to be common (37.9%), with checking being the most prevalent symptom. In mediation models, psychosis severity mediated checking behaviour indirectly by inducing obsessions (r = 0.07, 95% CI 0.04–0.09; P < 0.001). No direct effect of psychosis on checking was identified (r = −0.28, 95% CI −0.09 to 0.03; P = 0.340). After psychosis remission (n = 65), checking compulsions correlated with both clozapine plasma levels (r = 0.35; P = 0.004) and dose (r = 0.38; P = 0.002). None of the glutamatergic and serotonergic genetic variants were found to moderate the effect of psychosis on obsession and compulsion (SLC6A4, SLC1A1 and HTR2C) survived the multiple comparisons correction.
Conclusions
We elucidated different phases of the complex interplay of psychosis and compulsions, which may inform clinicians’ therapeutic decisions.
We extend the resolvent framework to two-phase flows with low-inertia particles. The particle velocities are modelled using the equilibrium Eulerian model. We analyse the turbulent flow in a vertical pipe with Reynolds number of $5300$ (based on diameter and bulk velocity), for Stokes numbers $St^+=0-1$, Froude numbers $Fr_z=-4,-0.4,0.4,4$ and $1/Fr_z = 0$ (gravity omitted). The governing equations are written in input–output form and a singular value decomposition is performed on the resolvent operator. As for single-phase flows, the operator is low rank around the critical layer, and the true response can be approximated using one singular vector. Even with a crude forcing model, the formulation can predict physical phenomena observed in Lagrangian simulations, such as particle clustering and gravitational effects. Increasing the Stokes number shifts the predicted concentration spectra to lower wavelengths; this shift also appears in the direct numerical simulation spectra and is due to particle clustering. When gravity is present, there are two critical layers, one for the concentration field, and one for the velocity field. For upward flow, the peak of concentration fluctuations shifts closer to the wall, in agreement with the literature. We explain this with the aid of the different locations of the two critical layers. Finally, the model correctly predicts the interaction of near-wall vortices with particle clusters. Overall, the resolvent operator provides a useful framework to explain and interpret many features observed in Lagrangian simulations. The application of the resolvent framework to higher $St^+$ flows in combination with Lagrangian simulations is also discussed.
Monism and pluralism are not only used to describe the ways in which international law becomes part of a domestic legal system but can also be applied to scholarship that seeks to explain the messiness of discrimination. According to Sophia Moreau's pluralist theory, the wrongfulness of discrimination can be summarized as three types of treatment: subordination, restriction, and exclusion. In this contribution, I will explore the role that power plays in her theory; while power is explicitly discussed in relation to subordination, it is less apparent from restriction and exclusion. However, as I will argue, power is a crucial element underpinning all forms of discrimination and all protected grounds.
From 1965 to 2020, the National Science Foundation constituted the single largest funding source for political science research. As such, the NSF played a central role in defining the cutting-edge of our discipline. This study draws on historical records of the American Political Science Association to examine the political and administrative contexts that shaped the funding priorities of the NSF Political Science Program. Additionally, the study presents a new dataset and analysis of the nearly three thousand projects funded over the 55-year life of the program. The dataset shows that NSF funding was principally channeled toward quantitative research, whereas qualitative methods received little support, and work advancing normative, critical, or interpretive approaches received virtually no support. The archival record and awards-level data make visible the material forces that shaped knowledge production, and they underline the NSF’s instrumental role in consolidating behavioralism and marginalizing non-positivist approaches. The study sheds new light on the history of the discipline and helps to contextualize some of the distinctive features of American political science.
This paper extends the work in Tee et al. (Intl J. Multiphase Flow, vol. 133, 2020, 103462) to investigate the effect of turbulent fluid motions on the translation and rotation of lifting and wall-interacting spheres in boundary layers. Each sphere was released from rest in smooth-wall boundary layers with $Re_\tau =670$ and 1300 ($d^+=56$ and 116, respectively) and allowed to propagate with the incoming fluid. Sphere and surrounding fluid motions were tracked simultaneously via three-dimensional particle tracking velocimetry and stereoscopic particle image velocimetry in streamwise–spanwise planes. Two-point correlations of sphere and fluid streamwise velocities yielded long positive regions associated with long fast- and slow-moving zones that approach and move over the spheres. The related spanwise correlations were shorter due to the shorter coherence length of spanwise fluid structures. In general, spheres lag the surrounding fluid. The less-dense lifting sphere had smaller particle Reynolds numbers varying from near zero up to 300. Its lift-offs coincided with oncoming fast-moving zones and fluid upwash. Wall friction initially retarded the acceleration of the denser sphere. Later, fluid torque associated with approaching high-velocity regions initiated forward rotation. The rotation, which was long-lived, induced sufficient Magnus lift to initiate repeated small lift-offs, reduce wall friction, and accelerate the sphere to higher sustained velocity. Particle Reynolds numbers remained above 200, and vortex shedding was omnipresent such that the spheres clearly altered the fluid motion. Spanwise fluid shear occasionally initiated wall-normal sphere rotation and relatively long-lasting Magnus side lift. Hence the finite sphere size contributed to multiple dynamical effects not present in point-particle models.
We study the motion and deformation of a single bubble rising inside a cylindrical container filled with a viscoelastic material. We solve numerically the mass and momentum balances along with the constitutive equation for the viscoelastic stresses, without assuming axial symmetry to allow the growth of three-dimensional disturbances. Hence, we may predict the emergence of the notorious knife-edge shape of the bubble, which is a result of a purely elastic instability triggered in the locality of the trailing edge. Our results compare well with existing experiments. We visualize, for the first time to the best of our knowledge, the flow kinematics and dynamics that arise downstream of the bubble. We propose two quantities, one kinematical and one geometrical, for the determination of the onset of the instability. We demonstrate that extension-rate thinning in the constitutive law is necessary for the emergence of the instability. Moreover, our results indicate that increasing (a) the deformability of the bubble and (b) the initial extension rate hardening of the viscoelastic material, prior to thinning, triggers the instability earlier. These novel findings help us formulate and propose a mechanism that controls the onset of the instability and explain why the knife-edge shape is not encountered as frequently.
To analyse the rate of contralateral nodal metastasis in human papillomavirus (HPV)-associated oropharyngeal carcinoma and identify the patient cohorts that would benefit from bilateral neck treatment.
Methods
A retrospective cohort review was performed on 110 HPV-positive oropharyngeal carcinoma patients who underwent transoral robotic surgery and bilateral neck dissections from 2012 to 2022. The primary outcome was to investigate the pathological incidence and location of contralateral neck node metastasis.
Results
The contralateral nodal disease rate was 12.7 per cent (n = 14), of which 2 patients (2 per cent) were occult findings, with comparable results between tongue base and tonsil sub-groups. The most commonly involved contralateral nodal station was level II (11 of 110 patients, 10 per cent). The presence of extra-nodal extension and multiple ipsilateral positive nodes was associated with increased risk of contralateral nodal disease.
Conclusion
The incidence of contralateral nodal and occult disease in the studied cohort is low. The characteristics of patients who may benefit from bilateral neck treatment were demonstrated.
Given maps $f_1,\ldots ,f_n:X\to Y$ between (finite and connected) graphs, with $n\geq 3$ (the case $n=2$ is well known), we say that they are loose if they can be deformed by homotopy to coincidence free maps, and totally loose if they can be deformed by homotopy to maps which are two by two coincidence free. We prove that: (i) if Y is not homeomorphic to the circle, then any maps are totally loose; (ii) otherwise, any maps are loose and they are totally loose if and only if they are homotopic.