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Trematodes and their snail hosts have developed intimate parasite-host associations, with snails supporting a diverse and often species-specific trematode fauna. In the faucet snail, Bithynia tentaculata (Caenogastropoda, Littorinimorpha), a unique trematode fauna has been recorded recently. However, knowledge of the exact species identity, phylogenetic relationships, and geographical distribution remains limited as many of the species belong to groups with unclear or controversial taxonomical assignment. To contribute to our knowledge of the trematodes, we investigated the trematode fauna of B. tentaculata by examining a total of 556 snails from lakes in County Galway, Ireland. Using an integrative taxonomic approach including DNA sequence data analyses (28S rRNA gene, ITS1-5.8S-ITS2, ITS2, cox1, nad1) and morphological tools (taxonomical drawings and measurements), we identified nine trematode species of seven families, with seven species occurring as cercariae (Cyathocotyle prussica, Lecithodendrium linstowi, Lecithodendrium sp., Asymphylodora progenetica, Sphaerostoma bramae, Metorchis xanthosomus, and Notocotylus sp.) and three species occurring as metacercariae (A. progenetica, Parasymphylodora parasquamosa, and Sphaeridiotrema sp.). Except for S. bramae, all are new species records for Ireland and provide the most western distribution of these trematodes in Europe. The trematode species recorded are known to use a wide range of definitive hosts and have a wide geographical distribution; among them are species members of genera that are zoonotic (Metorchis) and pathogenic to wildlife (Cyathocotyle, Sphaeridiotrema, and Notocotylus). There remains an ongoing need for precise identification of the trematode species to ensure that wider ecological contexts are correctly understood and biodiversity and disease threats can be accurately evaluated.
Scholars of Jin history have noted a flourishing literati culture after the mid-Jin period, but excavated tombs suggest a more complicated picture. The shi, referring to literati without official titles, constituted a prominent group in Northern Song tombs, as evidenced by their epitaphs, but this group appears to have nearly vanished from the Jin tombs. To search for traces of the shi, this article comprehensively examines the social elites’ tombs with burial inscriptions and ink writings, where the shi would most likely be laid to rest. It shows that the text and paratext of epitaphs, as well as the tombs that yielded them, contain direct information about the shi and their interactions with other officials and non-official elites. Analysis of ink writings suggests that the shi played a role in the advanced literary expression in the tombs of some non-literati local elites. Examining these traces of the shi in tombs allows us to reintegrate them into broader society, investigate their interactions with other elites, and attain a more holistic understanding of Jin elite society and culture.
The present work aims to extend the capabilities of DUST, a mid-fidelity aerodynamic solver developed at Politecnico di Milano, for the aerodynamic simulation of rotorcraft applications. With this aim, a numerical element was implemented in the solver obtained by a coupling between the potential unsteady vortex lattice method and viscous aerodynamic data of aerofoil sections available from two-dimensional high-fidelity computational fluid dynamics (CFD) simulations or experimental wind-tunnel tests. The paper describes the mathematical formulation of the method as well as a validation of the implementation performed by comparison with both high-fidelity CFD simulation results and experimental data obtained over aerodynamics and aeroelastic fixed-wing benchmarks. Then, the method was used for the evaluation of the aerodynamic performance of two rotorcraft test cases, i.e. the full-scale proprotor of the XV-15 tiltrotor operating in different flight conditions and two propellers in tandem with overlapping disks. Simulation results comparison with high-fidelity CFD and data from wind tunnel tests highlighted the potentialities and advantages of the implemented approach to be used for the design and investigation of rotorcraft configurations characterised by consistent viscosity effects.
Agimund's Homiliary is extant in two eighth-century manuscripts in BAV, Vat. lat. 3835 and 3836 and is one of the very few Roman texts actually written in Roman script surviving from the early Middle Ages. This article argues that the Homiliary is a crucial piece of evidence for early medieval Roman liturgical and cultural life and the patristic resources of Rome. Agimund's Homiliary, and the late eighth-century additions which are actually part of another, hitherto unidentified Roman Homiliary, together constitute evidence of the degree to which patristic theology and exegesis were embedded in Roman culture, of the interchange between the Latin- and Greek-speaking communities in Rome and the Lateran in the early Middle Ages, and of the intellectual productivity and cultural versatility of early medieval Rome.
Traction of the head-neck is important in the treatment of patients suffering from neck pain due to degeneration of the intervertebral discs. Conventional neck traction is provided manually by experienced physical therapists who maintain a desired orientation of the head-neck relative to the trunk while applying the traction. It is postulated that innovative designs of neck exoskeletons can provide the same function both flexibly and accurately. This article presents a novel architecture of a parallel mechanism whose base sits on the human shoulders with 4 parallel chains, each chain having a revolute-revolute-universal-revolute (RRUR) structure, while the end-effector is connected rigidly to the human head. Each chain has five degrees-of-freedom (DOF) and applies a constraint on the motion of the end-effector. As a result, this parallel mechanism allows two DOFs to the end-effector. These are (i) forward flexion or lateral bending of the head and (ii) vertical translation. An important motivation for the current design with RRUR structure is to characterize the range of forward flexion/lateral bending of the head-neck with this structure and the vertical translation to the end-effector. A physical prototype was constructed and tested to evaluate the performance of this mechanism in hardware for the proposed application.
Hybridization of parasitic species is an emerging health problem in the evolutionary profile of infectious disease, particularly within trematodes of the genus Schistosoma. Because the consequences of this hybridization are still relatively unknown, further studies are needed to clarify the epidemiology of the disease and the biology of hybrid schistosomes. In this article, we provide a detailed review of published results on schistosome hybrids of the haematobium group. Using a mapping approach, this review describes studies that have investigated hybridization in human (S. haematobium, S. guineensis, and S. intercalatum) and animal (S. bovis and S. curassoni) schistosome species in West Africa (Niger, Mali, Senegal, Côte d’Ivoire, Benin, Nigeria) and in Central Africa (Cameroon, Gabon, Democratic Republic of Congo), as well as their limitations linked to the underestimation of their distribution in Africa. This review provides information on studies that have highlighted hybrid species of the haematobium group and the regions where they have been found, notably in West and Central Africa.
This study introduces a hybrid model that utilizes a model-based optimization method to generate training data and an artificial neural network (ANN)-based learning method to offer real-time exoskeleton support in lifting activities. For the model-based optimization method, the torque of the knee exoskeleton and the optimal lifting motion are predicted utilizing a two-dimensional (2D) human–exoskeleton model. The control points for exoskeleton motor current profiles and human joint angle profiles from cubic B-spline interpolation represent the design variables. Minimizing the square of the normalized human joint torque is considered as the cost function. Subsequently, the lifting optimization problem is tackled using a sequential quadratic programming (SQP) algorithm in sparse nonlinear optimizer (SNOPT). For the learning-based approach, the learning-based control model is trained using the general regression neural network (GRNN). The anthropometric parameters of the human subjects and lifting boundary postures are used as input parameters, while the control points for exoskeleton torque are treated as output parameters. Once trained, the learning-based control model can provide exoskeleton assistive torque in real time for lifting tasks. Two test subjects’ joint angles and ground reaction forces (GRFs) comparisons are presented between the experimental and simulation results. Furthermore, the utilization of exoskeletons significantly reduces activations of the four knee extensor and flexor muscles compared to lifting without the exoskeletons for both subjects. Overall, the learning-based control method can generate assistive torque profiles in real time and faster than the model-based optimal control approach.
In sediments, clay minerals are mainly detrital. Formed by continental weathering, they are carried by surface transport predominantly by rivers, glaciers and, to a lesser extent, winds to the adjacent sedimentary basins and then are redistributed by oceanic currents. In a sedimentary core, the variability in the clay mineral assemblages reflects either variable physical and chemical weathering conditions in the watershed, typically with a significant link to climatic conditions, or changes in the mineral source, the latter being associated with various transport agents. When different sources are involved, a combination of mineralogical and geochemical proxies allows us to trace the detrital provenance, but they also indirectly provide valuable information on transport pathways and palaeocurrents. This manuscript reviews several examples from the literature and ongoing research on clay mineral variability in marine or lacustrine sedimentary records and interprets them in terms of: (1) climate control at different timescales, from the Neogene to the Quaternary; and (2) transport paths. Examples are selected to review the various clay-derived proxies in existence.
An interesting resurrection phenomenon (including the initial complete submersion, subsequent resurfacing and final rebounding) of a superhydrophobic sphere impacting onto a liquid bath was observed in experiments and direct numerical simulations by Galeano-Rios et al. (J. Fluid Mech., vol. 912, 2021, A17). We investigate the mechanisms of the liquid entry for a superhydrophobic cylinder in this paper. The superhydrophobic cylinder, commonly employed as supporting legs for insects and robots at the liquid surface, can exhibit liquid-entry mechanisms different from those observed with the sphere. The direct numerical simulation method is applied to the impact of a two-dimensional (2-D) superhydrophobic cylinder (modelled as a pseudo-solid) onto a liquid bath. We find that for the impacting cylinder the resurrection phenomenon can also exist, and the cylinder can either rebound (get detached from the liquid surface) or stay afloat after resurfacing. The cylinder impact behaviour is classified into four regimes, i.e. floating, bouncing, resurrecting (resurrecting-floating and resurrecting-bouncing) and sinking, dependent on the Weber number and the density ratio of the cylinder to the liquid. For the regimes of floating and bouncing, the force analysis indicates that the form drag dominates the motion of the cylinder in the very beginning of the impact, while subsequently the surface tension force also plays a role with the contact line pinning on the horizontal midline of the cylinder. For the critical states of the highlighted resurrecting regime, our numerical results show that the rising height for the completely submerged cylinder of different density ratios remains nearly unchanged. Accordingly, a relation between the maximum ascending velocity and the density ratio is derived to predict whether the completely submerged cylinder can resurface.
The influence of outer large-scale motions (LSMs) on near-wall structures in compressible turbulent channel flows is investigated. To separate the compressibility effects, velocity fluctuations are decomposed into solenoidal and dilatational components using the Helmholtz decomposition method. Solenoidal velocity fluctuations manifest as near-wall streaks and outer large-scale structures. The spanwise drifting of near-wall solenoidal streaks is found to be driven by the outer LSMs, while LSMs have a trivial influence on the spanwise density of solenoidal streaks, consistent with the outer LSM impacts found in incompressible flows (Zhou et al., J. Fluid Mech., vol. 940, 2022, p. A23). Dilatational motions are characterized by the near-wall small-scale travelling-wave packets and the large-scale parts in the outer region. The streamwise advection velocity of the near-wall structures remains at $16 \sim 18u_{\tau }$, hardly influenced by Mach numbers, Reynolds numbers and wall temperatures. The spanwise drifting of near-wall dilatational structures, quantified by the particle image velocimetry method, follows a mechanism distinct from solenoidal streaks. This drifting velocity is notably larger than those of the solenoidal streaks, and the influence of outer LSMs is not the primary trigger for this drifting.
We prove that the existence of one horosphere in the universal cover of a closed Riemannian manifold of dimension $n \geq 3$ with strongly $1/4$-pinched or relatively $1/2$-pinched sectional curvature, on which the stable holonomy along one horosphere coincides with the Riemannian parallel transport, implies that the manifold is homothetic to a real hyperbolic manifold.
Digital technology has enormous potential in rural revitalisation, thus providing impetus for improving the well-being of rural residents in underdeveloped areas. This study takes the policies of e-commerce in rural areas as an intervention in the development of e-commerce. It uses the panel data from 321 counties in the old revolutionary areas of China from 2003 to 2020 to empirically explore the impact of e-commerce development on the income of rural residents. Results show that e-commerce significantly improves the income and well-being of rural residents in old revolutionary areas. Propensity score matching and entropy balance matching are used to overcome group differences in covariate features, and the estimation results are consistently robust. In terms of mechanisms, e-commerce development increases per capita income in old revolutionary areas by promoting three aspects significantly: agricultural revitalisation, non-agricultural employment, and government support efforts. On the other hand, the heterogeneity analysis shows that e-commerce plays a diminishing role in increasing income in the eastern, central, and western regions.
Illegal poaching brought elephant species to the brink of extinction; therefore, international trade in ivory has become regulated by the Convention on International Trade in Endangered Species of Flora and Fauna (CITES). However, the trade is still allowed for antique items, standing for ivory from a period before 1947 within the European Union. This could serve as a loophole for the laundering of modern ivory. In the described case of the Happy Fisherman statuette, the traded item was declared to be antique, but radiocarbon analysis proved a modern provenance, and the statuette was confiscated. The radiocarbon analysis was later confirmed by information from a Chinese newspaper found inside the statuette. Based on the findings, we strongly recommend careful consideration of each individual ivory piece offered for sale, with a thorough inspection of the items and related documentation carried out by a relevant CITES authority. Any exemption of the commercial ban should be granted only to those applicants who meet the criteria of proper evidence in the form of scientific analysis or reliable and trustworthy documentation.
This study aimed to analyze the influence of different temperatures on the embryonic and larval development of discus fish Symphysodon aequifasciatus and determine the time required for the beginning of exogenous feeding. Eggs and larvae were obtained from natural spawns and distributed in five treatments: 24.0, 26.0, 28.0, 30.0, and 32.0 °C. To assess the developmental stages and embryonic structures, samples were taken at regular intervals and checked under an optical microscope. At the end of the experimental period, statistical analysis was performed, followed by Tukey’s test. As a result, it was possible to observe the significant effects of temperature on the variables. It was noted that the temperature accelerated the embryonic and larval development of the discus and also contributed to a reduction in the time between the incubation period and the feeding transition. It was also noted that the incubation of eggs and larvae at a temperature of 24.0 °C can cause damage to embryos, such as malformation of the body as well as anomalies in the circulatory system.
2022 - 2023 mpox outbreak necessitated rapid distribution of JYNNEOS vaccines from US Strategic National Stockpile to state and local public health agencies. New Hampshire’s centralized public health structure required partnering with healthcare facilities to reach at-risk persons. Among the 67 organizations contacted to partner with, only 7 established public JYNNEOS vaccine clinics. The study objective was to identify barriers and resources needed for emergency public vaccination.
Methods
In March 2023, mixed-method surveys were developed and sent to 20 non-participating organizations and 7 participating organizations (“vaccine-partners”).
Results
35% (7/20) of non-participating organizations and 100% (7/7) vaccine-partners responded. Non-participating organizations (n = 5) identified lack of staffing (100%) and insufficient provider time or clinical resources (80%) as the most common barriers. Staffing needs reported by non-participating organizations included: administrative (100%); medical doctor or advanced practice practitioner (67%); and registered nurse, medical assistant, or licensed nursing assistant (67%). Vaccine partners reported similar staffing requirements. Estimated additional monthly funding needs were $3,750 for non-participating organizations and $1,680 for vaccine-partners.
Conclusions
A minority of NH healthcare facilities established public JYNNEOS vaccination clinics. The primary barrier was insufficient staffing; additional resources and funding needs were modest. Success of the next emergency vaccination campaign depends on sustained advocacy, resources, and partnership.