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Let $E/F$ be a quadratic unramified extension of non-archimedean local fields and $\mathbb H$ a simply connected semisimple algebraic group defined and split over F. We establish general results (multiplicities, test vectors) on ${\mathbb H} (F)$-distinguished Iwahori-spherical representations of ${\mathbb H} (E)$. For discrete series Iwahori-spherical representations of ${\mathbb H} (E)$, we prove a numerical criterion of ${\mathbb H} (F)$-distinction. As an application, we classify the ${\mathbb H} (F)$-distinguished discrete series representations of ${\mathbb H} (E)$ corresponding to degree $1$ characters of the Iwahori-Hecke algebra.
A long-standing practice in clinical and developmental psychology research on childhood maltreatment has been to consider prospective, official court records to be the gold standard measure of childhood maltreatment and to give less weight to adults’ retrospective self-reports of childhood maltreatment, sometimes even treating this data source as invalid. We argue that both formats of assessment – prospective and retrospective – provide important information on childhood maltreatment. Prospective data drawn from court records should not necessarily be considered the superior format, especially considering evidence of structural racism in child welfare. Part I overviews current maltreatment definitions in the context of the developmental psychopathology (DP) framework that has guided maltreatment research for over 40 years. Part II describes the ongoing debate about the disproportionalities of minoritized children at multiple decision-making stages of the child welfare system and the role that racism plays in many minoritized families’ experience of this system. Part III offers alternative interpretations for the lack of concordance between prospective, official records of childhood maltreatment and retrospective self-reports, and for the differential associations between each format of data with health outcomes. Moving forward, we recommend that future DP research on childhood maltreatment apply more inclusive, diversity and equity-informed approaches when assessing and interpreting the effects of childhood maltreatment on lifespan and intergenerational outcomes. We encourage future generations of DP scholars to use assessment methods that affirm the lived experiences of individuals and families who have directly experienced maltreatment and the child welfare system.
In this commentary, I consider Mariátegui's globality. I begin by discussing his status as the pre-eminent Latin American Marxist. I then consider the fact that he continues to be ignored or marginalised by scholarship in English on Marxism and the global history of the Left. I note, however, that in recent years, ‘global’ interest in Mariátegui (i.e. beyond Latin America) has increased. This leads me to a consideration of two types of Mariátegui's globality. First, a globality produced by his growing purchase as an ‘epistemologist of the South’ which is extending the applicability of his thought beyond Latin America. And second, a globality expressive of his role as a global actor; as someone who (i) sought to experience life globally, (ii) drew on global ideas, or ideas with globalising (or universalising) ambitions, to make sense of his own (local) context, and (iii) operated as an original interpreter of the global.
In this paper we determine the homotopy types of the reduced suspension space of certain connected orientable closed smooth $five$-manifolds. As applications, we compute the reduced $K$-groups of $M$ and show that the suspension map between the third cohomotopy set $\pi ^3(M)$ and the fourth cohomotopy set $\pi ^4(\Sigma M)$ is a bijection.
We set up a formal framework to characterize encompassing of nonparametric models through the $L^2$ distance. We contrast it to previous literature on the comparison of nonparametric regression models. We then develop testing procedures for the encompassing hypothesis that are fully nonparametric. Our test statistics depend on kernel regression, raising the issue of bandwidth’s choice. We investigate two alternative approaches to obtain a “small bias property” for our test statistics. We show the validity of a wild bootstrap method. We empirically study the use of a data-driven bandwidth and illustrate the attractive features of our tests for small and moderate samples.
The work of the late Alejandro García-Rivera has been overlooked as a contribution to theological engagement with science. A significant obstacle to appreciating it as such is the view that his theological cosmology marks a problematic shift from Latinx theological aesthetics to an uncritical engagement with the work of Pierre Teilhard de Chardin. This article engages his oeuvre in response to that critique. Using Hans Urs von Balthasar’s concept of “theo-drama,” it argues that García-Rivera not only fits Teilhard into the broader mosaic of his work successfully, but that García-Rivera’s final work illumines his whole oeuvre as a “gift to science.” It shows how García-Rivera adapts his account of the beauty in the “little stories” of the pueblo to little places in the natural world, in order to help us see their beauty as an objective reality calling us to participate in their care. Thus, the article portrays García-Rivera’s body of work as a way to engage the scientifically-minded through a sensibility for natural beauty, born of mestizaje, popular piety, and the cross.
I focus on two main points in Ian Proops’s reading of Kant’s Paralogisms of Pure Reason: the structure of the paralogisms in the A edition of the Critique of Pure Reason, and the changes in Kant’s exposition of the paralogisms from A to B. I agree with Proops that there are defects in the A exposition and that Kant attempted to correct those defects in B. But I argue that Proops fails to give its due to what remains fundamental in both editions: Kant’s criticism of the rational psychologist’s confusion between the subjective (albeit universally subjective) standpoint thinkers have on themselves just in virtue of thinking, and the objective, metaphysical standpoint on a thinking thing. In short, Proops fails to give sufficient attention to Kant’s opening statement in the Paralogisms of Pure Reason: ‘“I think” is the sole text of rational psychology’.
Pain management for infants undergoing cardiothoracic surgery primarily utilises opioid analgesics. There is a paucity of data available for the use of non-steroidal anti-inflammatory medications such as ketorolac in this patient population.
Materials and Methods:
This retrospective study evaluated patients between 30 days and 6 months undergoing cardiothoracic surgery. The primary endpoint evaluates ketorolac on reducing post-operative opioid use.
Results:
Of 243 evaluated patient, 145 met inclusion. Baseline demographics were similar amongst the cohorts. Patients administered ketorolac used less cumulative opiates, in morphine milligram equivalents, for post-op days (POD) 1–3 after surgery compared to patients not receiving ketorolac (9.47 versus 12.68; p = 0.002). The no-ketorolac group required more opiates on POD 1 (10.9 versus 5; p < 0.001) and POD 2 (4.2 versus 2.5; p = 0.006) with no difference found on POD 3 (2 versus 1.6; p = 0.2). There was a mean increase from baseline to highest serum creatinine level on POD 1–3 in the no-ketorolac group compared to the ketorolac group (0.15 versus 0.09 mg/dL; p < 0.014), with no difference in stage 1 or stage 2 acute kidney injury. There were no differences in average chest tube output in mL/kg/day (0.24 versus 0.32; p = 0.569) or need for transfusion (36% versus 24%; p = 0.125), respectively.
Discussion:
Scheduled administration of ketorolac after cardiothoracic surgery resulted in a significant reduction in opioid exposure, with no difference in rates of acute kidney injury or bleeding.
The study of species association is of great interest in ecology due to its role in understanding key issues such as patterns of habitat use by animals, species coexistence, biotic interactions, and in general factors affecting community structure and assembly. There are many indices that ecologists commonly use, all based on the observed frequencies of organism occurrences, to evaluate the association between a pair of species. However, few of these indices correspond to proper statistical measures of association, and the inferential aspects of their analysis are often overlooked. In this paper, we propose a Bayesian approach based on a simple multinomial-Dirichlet structure to provide a comprehensive inferential framework for any set of association indices. Our approach provides a full statistical analysis for any association index of interest, free of special requirements on the sample size. We illustrate our procedure with a camera-trapping real-dataset, but the analysis of any other dataset of the same type can be readily produced using the R package basa that accompanies this paper.
This article examines the rise of a culture of local petitioning, through which growing numbers of ordinary people sought to win the support of state authorities through collective claims to represent the “voice of the people” at the local level. These participatory, subscriptional practices were an essential component in the intensification of popular politics in the seventeenth century. The analysis focuses on over 3,800 manuscript petitions submitted to the magistrates across fifteen jurisdictions with “sessions of the peace” in England, with nearly 1,000 dating from before 1640. Over the course of the early seventeenth century many, if not most, English parishes witnessed attempts to persuade the authorities through collective petitioning. Groups of neighbors across the kingdom formulated their grievances, organized subscription lists, and articulated their own role in the polity as “the inhabitants” or “the parishioners” of a particular community. In so doing, they not only directly shaped their own “little commonwealths” but also unintentionally helped to develop habits of political mobilization in a crucial period of English history.
The Dominican friar Johannes Nider (1380–1438), known today as the father of witchcraft literature, played an important role at the Council of Basel (1431–49) on the Council's delegation to the Hussites and its deputation on religious reform. Despite Nider's reputation as a reformer of religious communities, his approach to communal liturgy has not attracted close attention. This article focuses on his broad theoretical treatise, De reformatione religiosorum or De reformatione status cenobitici (On the Reform of the Religious State), in which Nider articulates a philosophical concept of reform as the restoration of beauty, manifested in well-ordered and balanced proportion. In the interest of universal applicability, the treatise remains abstract. However, biographical descriptions of Nider from his contemporaries and the visitation letters he wrote to women's convents show Nider as an engaged liturgical leader, a talented singer with a robust voice, and a zealous expert in the legal particulars of Dominican liturgical regulations. In light of these contexts, De reformatione's sweeping laments over liturgical neglect and academic metaphors of well-disposed proportion are not just rule-hammering and scholastic fancy but rather universalized expressions of Nider's lived commitment to Dominican musical and ritual practice.
The impact of eugenics on the early-twentieth-century scientific community was vast, including nearly all evolutionary scientists, paleontologists, and biologists. The Jesuit Pierre Teilhard de Chardin, a French paleontologist, was no exception. This article analyzes the full extent and impact of racist and eugenic ideas in Teilhard’s writings between 1905 and 1955. It examines the underlying causes of eugenics as specific philosophical and scientific arguments and traces the lineage of these arguments within the writings and letters of Teilhard. This research reveals a consistent colonialist and paternalistic racism within Teilhard’s writings, as well as a firm commitment to eugenics in the last fifteen years of his life. This study concludes with a review of the lack of discussion of race and eugenics within Teilhardian scholarship, and points to a way forward.
Introducing new disease-modifying therapies (DMTs) for Alzheimer's disease demands a fundamental shift in diagnosis and care for most health systems around the world. Understanding the views of health professionals, potential patients, care partners and taxpayers is crucial for service planning and expectation management about these new therapies.
Aims
To investigate the public's and professionals’ perspectives regarding (1) acceptability of new DMTs for Alzheimer's disease; (2) perceptions of risk/benefits; (3) the public's willingness to pay (WTP).
Method
Informed by the ‘theoretical framework of acceptability’, we conducted two online surveys with 1000 members of the general public and 77 health professionals in Ireland. Descriptive and multivariate regression analyses examined factors associated with DMT acceptance and WTP.
Results
Healthcare professionals had a higher acceptance (65%) than the general public (48%). Professionals were more concerned about potential brain bleeds (70%) and efficacy (68%), while the public focused on accessibility and costs. Younger participants (18–24 years) displayed a higher WTP. Education and insurance affected WTP decisions.
Conclusions
This study exposes complex attitudes toward emerging DMTs for Alzheimer's disease, challenging conventional wisdom in multiple dimensions. A surprising 25% of the public expressed aversion to these new treatments, despite society's deep-rooted fear of dementia in older age. Healthcare professionals displayed nuanced concerns, prioritising clinical effectiveness and potential brain complications. Intriguingly, younger, better-educated and privately insured individuals exhibited a greater WTP, foregrounding critical questions about healthcare equity. These multifaceted findings serve as a guidepost for healthcare strategists, policymakers and ethicists as we edge closer to integrating DMTs into Alzheimer's disease care.
In phonological theory there are multiple ways to represent mid vowels. SPE conventions maintain that they are non-[high] and non-[low]. Conversely, frameworks like Element Theory argue that mid vowels are simultaneously [high] and [low]. This article examines eight processes (and groups of processes) within the Germanic language family, which strongly indicate their specification as simultaneously [high] and [low]. That specification is manifest from developments that tease out the [high] and [low] features of a single mid vowel into separate [high] and [low] elements of sound (e.g., [e] > [ja]). It also falls out from changes in which separate [high] and [low] segments coalesce into a single mid vowel (e.g., [au] > [o]).
Ties of trade, credit and family provided the basis for trading networks between Hanseatic towns. They also, however, contained the seed for conflicts over fraud, debt and inheritance. Such disputes between burghers of different Hanseatic cities presented municipal governments with the particular challenge to balance their role as Hanseatic partners with an obligation of externally representing their own burghers. Focusing on relations between the cities of Lübeck and Reval, this article explores the variety of diplomatic strategies and tactics which city councils employed to preserve the political and economic benefits of intercity co-operation.