We report a case of dilated cardiomyopathy-like hypertensive cardiomyopathy (HTN-CM) with polycystic kidney disease without family history when a 3-month-old boy developed bacteraemia secondary to a urinary tract infection. He was later confirmed as having autosomal recessive inheritance due to the proven PKHD1 gene mutation. The treatment consisted mainly of antihypertensive and anti-heart failure therapies and he was discharged on the 131st day. To prevent the development of heart failure in patients with HTN-CM due to autosomal recessive polycystic kidney disease (ARPKD), it is important to improve the fetal diagnosis rate of ARPKD, detect hypertension early, and strictly control the blood pressure after birth.

A perennial problem for sociolinguists interested in morphosyntactic variation is that such forms are often low frequency, making quantitative analysis difficult or impossible. However, sociolinguists have been generally reluctant to adopt methodologies from syntax, such as acceptability data gleaned from speaker intuition, due to the belief that these judgments are not necessarily reliable. In this article we present data from the Scots Syntax Atlas, which employs sociolinguistic methodologies in spoken data alongside the results of acceptability judgments. We target three morphosyntactic variables and compare and contrast these across the two data types in order to assess the reliability of the judgment data at community level. The results show that reliability is variable-dependent. For some variables, there is clear correlation; with others, it appears that, as Labov (1996) phrased it, ‘intuitions fail’. We discuss how factors such as salience, social stigma and local identity combine to govern the reliability of judgment data.

In order to solve the problem of the insufficient adaptability of the current small- and medium-sized casting sorting robot gripper, we have designed a casting sorting robot bionic gripper with rigid–flexible coupling structures based on the robot topology theory. The second-order Yeoh model was used to statically model the clamping belt in the gripper to derive the relationship between the external input air pressure and the bending angle of the driving layer, and the feasibility of multiangle bending of the driving layer was verified by finite element analysis. The maximum gripping diameter of the gripper is 140 mm, and in order to test the adaptive gripping ability of the gripper, a prototype of the casting sorting robot gripper is prepared, and the pneumatic control system and human–machine interface of the gripper are designed. After several experimental analyses, the designed casting sorting robot gripper is characterized by strong adaptability and high robustness, with a maximum load capacity of 930 g and a maximum wrap angle of 296°, which can complete the gripping operation within 1 s, and the comprehensive gripping success rate reaches 96.4%. The casting sorting robot gripper designed in the paper can provide a reference for the design and optimization of various types of shaped workpiece gripping manipulators.

Physical vapor deposited (PVD) molybdenum disulfide (nominal composition MoS2) is employed as a thin film solid lubricant for extreme environments where liquid lubricants are not viable. The tribological properties of MoS2 are highly dependent on morphological attributes such as film thickness, orientation, crystallinity, film density, and stoichiometry. These structural characteristics are controlled by tuning the PVD process parameters, yet undesirable alterations in the structure often occur due to process variations between deposition runs. Nondestructive film diagnostics can enable improved yield and serve as a means of tuning a deposition process, thus enabling quality control and materials exploration. Grazing incidence X-ray diffraction (GIXRD) for MoS2 film characterization provides valuable information about film density and grain orientation (texture). However, the determination of film stoichiometry can only be indirectly inferred via GIXRD. The combination of density and microstructure via GIXRD with chemical composition via grazing incidence X-ray fluorescence (GIXRF) enables the isolation and decoupling of film density, composition, and microstructure and their ultimate impact on film layer thickness, thereby improving coating thickness predictions via X-ray fluorescence. We have augmented an existing GIXRD instrument with an additional X-ray detector for the simultaneous measurement of energy-dispersive X-ray fluorescence spectra during the GIXRD analysis. This combined GIXRD/GIXRF analysis has proven synergetic for correlating chemical composition to the structural aspects of MoS2 films provided by GIXRD. We present the usefulness of the combined diagnostic technique via exemplar MoS2 film samples and provide a discussion regarding data extraction techniques of grazing angle series measurements.

Premodern medicine used a variety of mineral substances for therapeutic purposes. The present article deals with pitch-asphalt, and, in particular, a precious kind of it called mūmiyāʾ originating in Persia. It was first described in detail in the Arabic pharmacological tradition, and its fame spread throughout the medieval Mediterranean, including Byzantium. By editing and examining for the first time a previously unexplored medieval Greek text on mūmiyāʾ, this study offers new insights into the medicinal uses of this substance. It also significantly increases our understanding of the intense cross-cultural transfer of medical knowledge from the Islamicate world to Byzantium by showing that this was not merely based on the translation of a few Arabic medical works into Greek, but was a multifaceted phenomenon involving a complex nexus of sources that require further investigation.

We study the asymptotic behaviour of the least energy solutions to the following class of nonlocal Neumann problems:

$$ \begin{align*} \begin{cases} { d(-\Delta)^{s}u+ u= \vert u\vert^{p-1}u } & \text{in } \Omega, \\ {u>0} & \text{in } \Omega, \\ { \mathcal{N}_{s}u=0 } & \text{in } \mathbb{R}^{n}\setminus \overline{\Omega}, \end{cases} \end{align*} $$

where $\Omega \subset \mathbb {R}^{n}$ is a bounded domain of class $C^{1,1}$, $1<p<({n+s})/({n-s}),\,n>\max \{1, 2s \}, 0<s<1, d>0$ and $\mathcal {N}_{s}u$ is the nonlocal Neumann derivative. We show that for small $d,$ the least energy solutions $u_d$ of the above problem achieve an $L^{\infty }$-bound independent of $d.$ Using this together with suitable $L^{r}$-estimates on $u_d,$ we show that the least energy solution $u_d$ achieves a maximum on the boundary of $\Omega $ for d sufficiently small.

Animal experimentation raises value conflicts between animal protection and other goods, such as freedom of inquiry or health and safety. If governments can phase out the practice by non-prohibitive incentive-setting, the pro tanto moral rationale for doing so is obvious. So why should they not? This article first sketches a fictional scenario in which a government adopts a phase-out plan for animal experimentation. It then considers two moral objections to this plan: First, the plan unduly restricts freedom of inquiry, and second, it merely displaces animal experimentation across borders and thus fails to reduce animal suffering. Both arguments are refined premise by premise to articulate their strongest versions. The two objections can help to narrow down desiderata for good phase-out plans. However, they do not provide a compelling case against phase-out planning as such because they miss its incremental and constructive nature. Unless better arguments can be provided, it appears that government inaction on phasing out animal experimentation lacks moral justification.

Congenital mitral stenosis is a rare anomaly. We report successful surgical management of congenital mitral stenosis in a patient with Kabuki syndrome. A 15-month-old male with Kabuki syndrome was referred and echocardiography showed isolated congenital mitral stenosis. The valve was not repairable as it was showing severe stenotic features in multilevel fashion. Valve was replaced with mechanical valve. Postoperative course was uneventful without any rhythm problem and he has been doing well clinically during the 25 months follow-up with regular international normalized ratio checks.

The field of International Studies has often been concerned with either negative conceptualisations of freedom and liberty (i.e. freedom from obstacles and interference) or positive notions of freedom (i.e. the possibility to act and develop). Further, these two notions of freedom have been conceived of as rival and incompatible. Drawing upon Simone de Beauvoir’s ethics of ambiguity (1947), this article rejects such a binary conceptualisation of freedom and instead puts forward a relational understanding of freedom. This article also begins to sketch the possibilities offered by such an understanding of freedom via a nascent dialogue between this relational freedom and the ethics of care. Specifically, it is posited that care and freedom weave together to form the very ethical space and conditions in and through which in becomes possible to pursue various life projects in the first place. Care and freedom, it is suggested, may thus provide one orientation for studying and practising international relations in a manner that moves towards building, amending, and maintaining relations that better support everyone (where this, crucially, also entails the ending of relations which oppress, harm, and cause suffering).

This article highlights CSR disclosure as a strategic response of Chinese multinational enterprises (MNEs) to the social risk they face in host countries. Deviating from prior research that aims to directly measure social risk, we offer a new approach to isolate the effect of social risk by leveraging China's Belt & Road Initiative (BRI) as the research context, under which Chinese MNEs are largely protected from political risk in membership countries but are exposed to substantial social risk from local nongovernment stakeholders. Results from difference-in-differences analyses show that after the enactment of the BRI, Chinese MNEs investing in BRI countries significantly increases their likelihood of CSR disclosure than that of their counterparts investing in non-BRI countries. Further, such effects are more pronounced for state-owned MNEs and MNEs in natural resource industries. This research enriches the international business literature on the relationship between political risk and social risk, and that between corporate political actions and corporate social responsibility.

This article reconstructs the first outbreak of epidemic dropsy recorded in documentary evidence, which occurred in Calcutta, Mauritius, and northeastern India and Bengal in 1877–80. It uses current medical knowledge and investigations into the wider historical contexts in which the epidemic occurred to re-read the colonial medical literature of the period. It shows that colonial policies and structures in the context of variable enviro-climatic conditions increased the likelihood that an epidemic would break out, while also increasing the vulnerability of certain populations to infection and mortality. Additionally, it shows how the trans-regional nature of the epidemic contributed to varying understandings of the disease between two colonial medical establishments, which influenced each other in contradictory ways. The article’s core contributions are to recent trans-regional perspectives on disease transmission and colonial medical knowledge production in the Indian Ocean World.

We study analogues of Kronecker coefficients for symmetric inverse semigroups, for dual symmetric inverse semigroups and for the inverse semigroups of bijections between subquotients of finite sets. In all cases, we reduce the problem of determination of such coefficients to some group-theoretic and combinatorial problems. For symmetric inverse semigroups, we provide an explicit formula in terms of the classical Kronecker and Littlewood–Richardson coefficients for symmetric groups.