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The evaluation of usual food intake is of central importance in nutritional epidemiology studies. Some authors propose the usual dietary recall (UDR) as a viable method for assessing usual food intake; however, its characteristics remain poorly understood. The objective of this study is to review the literature on the application and performance characteristics of the UDR as a dietary assessment method. Electronic search strategies were conducted using the Excerpta Medica Database, Publisher Medline, Cochrane Central Register of Controlled Trials, Latin American and Caribbean Health Sciences Literature, Coordination for the Improvement of Higher Education Personnel (CAPES) Periodicals Portal, and Google Scholar. Studies published in Portuguese, English, and Spanish were included, with no restrictions on publication date. Eligible studies included those utilising the UDR in experimental or observational designs, as well as literature reviews. A total of 116 studies were included in the review. The most common application method (n 34; 29·3 %) involved reporting foods typically consumed over a 24-h period. However, most studies (n 66; 56·9 %) did not specify the method for applying the UDR. Key limitations identified included under or overestimation (n 9; 7·8 %), memory bias (n 7; 6·0 %) and the lack of instrument validation (n 5; 4·3 %). Findings show that the UDR lacks a standardised application method, and its validity remains unconfirmed. Future research should establish a standardised protocol and assess its psychometric properties to reduce errors and biases, ensuring accurate dietary assessments in nutritional epidemiology.
This paper is situated within the context of the onset of British imperialism in Nigeria at the end of the nineteenth century, with a particular focus on the conquest of the Ijebu Kingdom. The episode, as discussed in the paper, is intended for stage or screen theatrical adaptation. It demonstrates the value of historical dramatization based on data foregrounded by standard historical and relevant research methodologies. The principal text in the paper, derived from primary and research-based sources, is outlined in a chronological narrative. The general idea is to enable the development of a script to create a historical drama.
L-carnitine is essential for myocardial metabolism, and its depletion may compromise heart function. We conducted a prospective observational study to assess serum carnitine profiles in 26 children under 36 months of age undergoing elective open-heart surgery with cardiopulmonary bypass. Measurements included free carnitine, acylcarnitine, and the acylcarnitine-to-free carnitine ratio, recorded preoperatively and at multiple postoperative time points up to 24 hours. We observed a significant postoperative decline in free carnitine and an increase in the acylcarnitine-to-free carnitine ratio, both of which correlated with cardiopulmonary bypass duration. These results highlight a perioperative disturbance in carnitine metabolism, suggesting potential relevance for postoperative cardiac recovery.
We propose an evolutionary competition model to investigate the green transition of firms, highlighting the role of adjustment costs, state-dependent transition risk, and positive externalities in green technology adoption. Firms base their decisions to adopt either green or brown technologies on relative performance. To incorporate the costs of switching to another technology into their decision-making process, we adopt a novel, ad hoc crafted, replicator dynamics. Our global analysis reveals that increasing transition risk, e.g., by threatening to impose stricter environmental regulations, effectively incentivizes the green transition. Economic policy recommendations derived from our model further suggest maintaining high transition risk regardless of the industry’s level of greenness. Subsidizing the costs of adopting green technologies can reduce the risk of a failed green transition. While positive externalities in green technology adoption can amplify the effects of green policies, they do not completely eliminate the possibility of a failed green transition. Finally, evolutionary pressure reduces the extent of green economic policies required to ensure a successful green transition.
In the paper, we consider a two-dimensional free-surface flow past a single point vortex in fluid of infinite depth. The flow moves from left to right with uniform speed $c$ far upstream and is subject to the downward acceleration $g$ of gravity. A point vortex of circulation $\varGamma$ is located at depth $H$. The positive direction of circulation is counterclockwise. The flow is characterised by two dimensionless parameters which are the dimensionless vortex circulation $\gamma =\varGamma /(\textit{cH}\,)$ and the Froude number $ \textit{Fr}=c/\sqrt {gH}$. The goal of the paper is to find the solutions of the solitary wave type with one or several crests on the free surface. These solutions are waveless far downstream and have a vertical line of symmetry. We have established that for a fixed Froude number $ \textit{Fr}\le 0.8$, there exists a finite set of positive $\gamma$ for which the solutions of the solitary wave type occur.
This study examines public-private partnerships (PPPs) in home- and community-based services (HCBS) for older adults in Guangzhou, China, amid growing efforts to increase non-state actor participation and market mechanisms in welfare provision. Based on semi-structured interviews with non-state actors, this research examines both contractual and relational dimensions of PPPs and why achieving their full potential remains challenging. Findings reveal that state actors maintain a leading role in PPPs, with non-state actors primarily positioned as implementers of predefined welfare objectives. The power imbalance embedded in China’s sociopolitical context blurs the boundaries among the Party, state, and society, shaping coordination challenges in PPPs. These structural constraints hinder integrated service delivery and limit the extent to which PPPs can meaningfully leverage the expertise of various actors. This study enhances understanding of PPPs in China’s authoritarian, state-led market context and offers insights into the evolving landscape of welfare socialisation reforms.
Divine simplicity is plausibly seen as a biblical doctrine, given a standard account of the way doctrine is derived from Scripture. The polemic of Jeremiah 10 against ancient Near Eastern mis pî or ‘mouth opening’ rituals involves a commitment to a radical account of divine aseity. In dialogue with Thomas Aquinas and a number of contemporary figures, I suggest this view of divine aseity might plausibly be thought to lead to the inference to divine simplicity.
While early-life adverse experiences have been linked to late-life cognitive decline, few studies have explored war exposure. Paradoxically, one study even indicated a late-life cognitive advantage of early-childhood war exposure. In the present study, we explored these associations.
Methods:
We examined older adults exposed to World War II (1940–1944; n = 1179) and the subsequent Civil war (1946–1949; n = 962) in Greece during early and middle childhood with a comprehensive neuropsychological assessment and for ApoE-ε allele status, including demographic information and medical history.
Results:
Higher cognitive performance in language tasks predicted middle childhood, relative to early childhood, WWII-exposure group membership (B = .316, p = .038, OR:1.372, 95%CI:1.018–1.849), primarily for men, while higher attention/speed (B = .818, p = .002, OR:2.265, 95%CI:1.337–3.838) and total cognitive score (B = .536, p = .040, OR:1.709, 95%CI:1.026–2.849) were predictors of belonging to the middle-childhood group, only in men. Individuals who did not meet criteria for Mild Cognitive Impairment (MCI)/dementia were more likely to belong to the middle-childhood war-exposure group. Similarly, for the Civil war, higher cognitive scores and reduced likelihood to meet criteria for MCI/dementia were predictors of middle, relative to early childhood war exposure group membership (visuospatial score: B = .544, p = .001, OR:1.723, 95%CI:1.246–2.381, MMSE: B = .134, p = .020, OR:1.143, 95%CI:1.021–1.297), primarily for women. Results remained consistent when adjusting for multimorbidity, sex, education, current age, depression, and anxiety.
Conclusion:
The present findings suggest that better cognitive performance and lower likelihood of MCI or dementia were associated with being exposed to significant hardships, such as war, during middle childhood, regardless of potentially confounding factors. Further studies are needed to shed light on this relationship.
Granular flow down an inclined plane is ubiquitous in geophysical and industrial applications. On rough inclines, the flow exhibits Bagnold’s velocity profile and follows the so-called $\mu (I)$ local rheology. On insufficiently rough or smooth inclines, however, velocity slip occurs at the bottom and a basal layer with strong agitation emerges below the bulk, which is not predicted by the local rheology. Here, we use discrete element method simulations to study detailed dynamics of the basal layer in granular flows down both smooth and rough inclines. We control the roughness via a dimensionless parameter, $R_a$, varied systematically from 0 (flat, frictional plane) to near 1 (very rough plane). Three flow regimes are identified: a slip regime ($R_a \lesssim 0.45$) where a dilated basal layer appears, a no-slip regime ($R_a \gtrsim 0.6$) and an intermediate transition regime. In the slip regime the kinematics profiles (velocity, shear rate and granular temperature) of the basal layer strongly deviate from Bagnold’s profiles. General basal slip laws are developed that express the slip velocity as a function of the local shear rate (or granular temperature), base roughness and slope angle. Moreover, the basal layer thickness is insensitive to flow conditions but depends somewhat on the interparticle coefficient of restitution. Finally, we show that the rheological properties of the basal layer do not follow the $\mu (I)$ rheology, but are captured by Bagnold’s stress scaling and an extended kinetic theory for granular flows. Our findings can help develop more predictive granular flow models in the future.
Autonomous manoeuvre decision-making is essential for enhancing the survivability and operational effectiveness of unmanned aerial vehicles in high-risk and dynamic air combat scenarios. To address the limitations of traditional air combat decision-making methods in dealing with complex and rapidly changing environments, this paper proposes an autonomous air combat decision-making algorithm based on hybrid temporal difference error-reward prioritised experience replay with twin delayed deep deterministic policy gradient. This algorithm constructs a closed-loop learning system from environmental interaction to policy optimisation, addressing the key challenges of slow convergence and insufficient identification of critical tactical decisions in autonomous air combat. A hybrid priority metric leveraging reward backpropagation and temporal difference error filter is introduced to optimise the learning of high-value experiences while balancing sample diversity and the reuse of critical experiences. To reduce excessive trial and error in the initial phase, an integrated reward function combining task rewards and auxiliary guidance rewards is designed using the reward reshaping method to guide the agent on how to choose a manoeuvre strategy. Based on the established three-dimensional close-range air combat game model, simulation validations were conducted for both basic manoeuvre and expert system engagements. The results demonstrate that the proposed autonomous air combat manoeuvre decision-making algorithm exhibits higher learning efficiency and convergence stability. It can rapidly identify high-value manoeuvres and effectively formulate rational yet superior tactical strategies in the face of complex battlefield scenarios, demonstrating obvious benefits in enhancing combat effectiveness and tactical adaptability.
The classical account of administrative law, which holds that unlawful administrative acts are void ab initio and that judicial review remedies such as quashing orders are merely declaratory of such acts’ legal status, appears to be placed in doubt by a range of recent legislative developments, judicial pronouncements and academic commentary. However, the classical account is not only capable of withstanding those apparent challenges: it is constitutionally imperative if collateral challenge is to be maintained and the rule of law thereby upheld.
This article examines Taiwan’s approach of using government-issued contractual templates to regulate unfair terms in standard forms for consumer transactions. This article studies user agreements from a sample of two different types of electronic payment service providers (PSPs) in Taiwan, one operating under a more stringent regulatory framework and the other subject to lighter regulation. This article finds that PSPs largely adhere to the templates even when they are not obliged to do so, indicating the effectiveness of the template approach for PSPs. However, PSPs often adopt or adapt template terms in ways that maximise flexibility. This is in line with the behavioural assumption that businesses modify template terms that do not meet their business interests. Moreover, where government-issued templates are widely adopted by firms in an industry, templates begin to function like regulatory rules. In these cases, greater transparency in the creation of contractual templates is required to legitimise their role in regulating unfair terms in consumer contracts.
Optic neuritis (ON) represents the most common optic neuropathy in young adults; however, longitudinal data on visual recovery, particularly in autoimmune ON subtypes, remain limited. This study aimed to assess long-term visual outcomes in patients with severe ON without multiple sclerosis stratified by autoantibody status: aquaporin-4 (AQP4)-IgG positive, myelin oligodendrocyte glycoprotein (MOG)-IgG positive and double seronegative (DN).
Methods:
A retrospective cohort analysis was conducted at a tertiary neurology center in southern India, including severe ON patients (best-corrected visual acuity [BCVA] ≤1.0 logMAR) between January 2016 and April 2024. Serological testing for AQP4 and MOG antibodies was performed via cell-based assays. Visual outcomes were categorized as “good recovery” (≥66.77% improvement in BCVA) and “complete recovery” (return to baseline BCVA).
Results:
Among 42 patients, 17 were AQP4-IgG positive, 10 MOG-IgG positive and 15 DN. The median BCVA at nadir was 1.7 logMAR. Compared with that in the MOG-IgG group, the likelihood of complete visual recovery was lower in both the AQP4-IgG (hazard ratio [HR]: 0.18; p = 0.16) and DN (HR: 0.56; p = 0.34) groups. For good recovery, the AQP4-IgG (HR: 0.16; p = 0.001) and DN (HR: 0.24; p = 0.001) groups had significantly lower HR. All MOG-IgG–positive patients achieved good recovery, compared with fewer than half in the other groups.
Conclusion:
Antibody status predicted long-term visual outcomes in patients with isolated ON, with MOG-IgG conferring the best recovery, AQP4-IgG the worst and DN intermediate, underscoring the importance of early, antibody-guided management.
Disparities in clinical outcomes exist among children with CHD, and social determinants of health are a significant contributor. Follow-up care plays an important role in long-term health and may be impacted by social determinants of health. We aimed to describe the population with lapses in care to outpatient, general paediatric cardiology from a social determinants of health standpoint and compare them to our primary service area.
Methods:
A retrospective chart review was completed for children who had lapses in care within outpatient, general cardiology. Data were compared to the Cincinnati Children’s Hospital Medical Center’s primary service area population.
Results:
A higher proportion of patients who had lapses in care were noted to identify as Hispanic/Latino, utilised some form of public insurance, and lived in communities with more social deprivation.
Conclusion:
Patients who identify as a minority race/ethnicity, utilise public insurance, or live in an area with a higher social deprivation may be at a higher risk for lapses in outpatient cardiology care, including both follow-up care and initial evaluations.
The flow past a $6:1$ prolate spheroid at a moderate pitch angle $\alpha =10^\circ$ is investigated with a focus on the turbulent wake in a high-fidelity large eddy simulation (LES) study. Two length-based Reynolds numbers, ${\textit{Re}}_L=3\times 10^4$ and $9\times 10^4$, and four Froude numbers, ${\textit{Fr}} = \infty \text{(unstratified)}, 6, 1.9 \text{ and }1$, are selected for the parametric study. Spectral proper orthogonal decomposition (SPOD) analysis of the flow reveals the leading coherent modes in the unsteady separated flow at the tail of the body. At the higher ${\textit{Re}}_L=9\times 10^4$, a high-frequency spanwise flapping of shear layers on either side of the body is observed in the separated boundary layer for all cases. The flapping does not perturb the lateral symmetry of the wake. At ${\textit{Fr}}=\infty$, a low-frequency oscillating laterally asymmetric mode, which is found in addition to the shear-layer mode, leads to a sidewise unsteady lateral load. All temporally averaged wakes at ${\textit{Re}}=9\times 10^4$ are found to be spanwise symmetric in the mean as opposed to the lower ${\textit{Re}}=3\times 10^4$, at which the ${\textit{Fr}}=\infty \text{ and }6$ wakes exhibit asymmetry. The turbulent kinetic energy (TKE) budget is compared among cases. Here, ${\textit{Fr}}=\infty$ exhibits higher production and dissipation compared with ${\textit{Fr}}=6 \text{ and }1.9$. The streamwise vortex pair in the wake induces a significant mean vertical velocity ($U_z$). Therefore, in contrast to straight-on flow, the terms involving gradients of $U_z$ matter to TKE production. Buoyancy reduces $U_z$ and also the Reynolds shear stresses involving $u^{\prime}_z$. Through this indirect mechanism, buoyancy exerts control on the wake TKE budget, albeit being small relative to production and dissipation. Buoyancy, through the baroclinic torque, is found to qualitatively affect the streamwise vorticity. In particular, the primary vortex pair is extinguished in the intermediate wake and two new vortex pairs form with opposite-sense circulation relative to the primary.