Obesity and depression are highly prevalent diseases that are strongly correlated. At the same time, there is a growing gap in care, and treatment options should be improved and extended. Positive effects of a Mediterranean diet on mental health have already been shown in various studies. In addition to the physiological effects of nutrients, the way food is eaten, such as mindful eating, seems to play a role. The present study investigates the effect of a Mediterranean diet and mindful eating on depression severity in people with clinically diagnosed major depressive disorder and obesity. Participants will be randomised to one of the four intervention groups (Mediterranean diet, mindful eating, their combination and a befriending control group). The factorial design allows investigating individual effects as well as potential synergistic effects of the interventions. The study consists of a 12-week intervention period, where five individual appointments will take place, followed by a 12-week follow-up. The primary outcome is depression severity. Secondary outcomes are remission of depression, assessor-rated depression severity, quality of life, self-efficacy, BMI, waist:hip ratio and body composition; adherence to the Mediterranean diet and mindful eating will also be assessed. Alongside mediator and moderator analysis, a microbiome analysis, a qualitative evaluation and an economic analysis will be conducted. The study investigates an important health issue in a vulnerable target group. It allows to draw valuable conclusions regarding the effectiveness of different interventions and therefore contributes to improving available care options for people suffering from depression and obesity.

This brief article outlines a training programme, implemented during day-to-day practice, to teach psychodynamic skills to resident doctors in a variety of specialties and at all levels of training. By identifying and exploring the interpersonal dynamics between individual patients and staff, psychiatry residents learn skills such as psychodynamic assessment and formulation, intervention planning and risk reduction.

This article uses a legal dispute between two families over a small building in semi-rural Jiangsu, and the political scandal it led to during the Socialist Education Movement (1963–1966), as a lens through which to explore the Mao era legacies of two prominent themes in the historiography of late imperial China: concepts and practices of property and contract, and the use of false accusations to enlist the coercive power of the state in economic disputes. It argues that over the course of the 1950s, norms of ownership in rural China were gradually undermined. This went beyond what was intended by the Party leadership, and was followed, in 1961–1962, by an effort to stabilize the conventions of who could own what in socialist China. The article then goes on to consider how the pursuit of property claims through accusations of political crime in the Mao era compares to such practices in the late imperial period.

This article introduces a novel empirical method for estimating the ideological orientations of U.S. regulatory agencies across different presidential administrations. Employing a measurement model based on item response theory and analyzing data on planned regulations from the Unified Agenda and the president’s discretionary review of those regulations, as implemented by the Office of Information and Regulatory Affairs, the study provides dynamic estimates of agency ideal points from the Clinton through the Trump administrations. The model uses NOMINATE ideal points of presidents to link the estimated agency ideal points to legislative ideal points. The resulting estimates correlate positively with existing measures of agency ideology, highlight controversial regulators, and demonstrate that agency ideologies shift over time due to emerging issues that divide the parties. The study also finds that agencies located ideologically closer to the president are more productive, as evidenced by their regulatory output.

Kurt Gödel proved that it is not possible to characterize intuitionistic propositional logic (${IPL}$) by means of finite and deterministic truth-tables. After extending the same result with respect to non-deterministic matrices (Nmatrices), we provide a semantical characterization of ${IPL}$ by means of a $3$-valued Nmatrix with a restricted set of valuations. This structure allows to define an algorithm to delete unsound rows from the non-deterministic truth-tables generated for each formula, which constitutes a new and very simple decision procedure for ${IPL}$. This method can be seen as truth-tables in a broader sense, and a way to overcome Gödel’s limiting result.

In this article, we give a boundary rigidity result on some fibered domains. As an application, we obtain the boundary rigidity for holomorphic self-maps on bounded symmetric domains with an interior fixed point.

Levoatriocardinal vein is a rare venous anomaly occasionally presenting as a bidirectional shunt in structurally normal hearts. We describe two unique systemic connections of levoatriocardinal vein without intracardiac defects, one causing paradoxical embolism via the hemiazygos vein, and the other draining from the left jugular vein to the pulmonary vein, requiring surgical correction to preserve cerebral venous return.

In this paper, I investigate how parents should talk to their children about injustice. In doing so, I use the non-ideal theory debate in political philosophy to show how the questions traditionally asked there can give substantive guidance to parents. I also contribute to that debate by showing how attention to injustice conversations (a) leads us to ask new questions and develop new modelling tools; (b) can help us to resolve the questions traditionally asked in the debate in a more direct way; and (c) can serve as a model for bringing together substantive and methodological questions in non-ideal theory.

Previous studies have shown that low-fat diet (LFD) is associated with various health benefits, and that lipid and fatty acid metabolism is linked to telomere shortening. However, no epidemiological studies have examined the association between LFD and telomere length (TL). Dietary information was collected using 24-h recalls among 6981 adults from a nationwide cross-sectional study. Diet quality was assessed using overall LFD, healthful LFD (hLFD) and unhealthful LFD (uLFD). TL was measured using quantitative PCR. Linear regression was employed to evaluate the association between LFD and log-transformed TL, and ordinal logistic regression was performed to assess the association of LFD with ordinal quintiles of TL in descending order. In both fully adjusted linear and ordinal regression models, higher overall LFD (Tertile 3 v. Tertile 1: percentage change = 2·48 %, 95 % CI: 0·60 %, 4·40 %, Ptrend = 0·003; OR = 0·79, 95 % CI: 0·68, 0·93; Ptrend = 0·001) and hLFD (Tertile 3 v. Tertile 1: percentage change = 2·71 %, 95 % CI: 0·87 %, 4·58 %; Ptrend = 0·002; OR = 0·84, 95 % CI: 0·72, 0·97; Ptrend = 0·003) scores were significantly associated with longer TL. The positive association between hLFD and TL was observed in other racial/ethnic groups, but not in non-Hispanic whites (Pinteraction < 0·005). There was no significant association between uLFD and TL in all the models. Our results suggest that LFD rich in high-quality carbohydrates, unsaturated fat and plant protein is associated with longer TL and underscore the need to consider the quality and dietary sources of the macronutrients.

This article rethinks the political project of transforming sexual desire and the norms that regulate it, aiming to reduce oppression and marginalization in intimate life. In the wake of recent feminist revivals of this project, such as Amia Srinivasan’s The Right to Sex (2021), I analyze the limitations of two dominant frameworks: ‘disciplinary’ models, which overestimate our capacity to regulate desire, and ‘liberatory’ models, which assume the existence of an authentic, pre-political core of desire that can be freed from power. I argue that both models are flawed, promoting respectively the illusion of total control and prelapsarian fantasies. To move beyond them, I turn to Theodor W. Adorno’s concept of natural history, which challenges the fixity of desire without assuming its infinite malleability. Specifically, drawing on Adorno and his interpreters, I show the natural history provides a framework for conceptualizing agency and transformation that neither negates the constraints shaping desire nor forecloses the possibility of its active reconfiguration. This approach, I suggest, offers a critical foundation for feminist efforts to rethink and reshape desire.

The Indonesian government has alternately ignored and respected the customary land rights of local people in its land policies since colonial times. Since the start of democratisation at the end of the 1990s, the trend to uphold customary land rights has become apparent at the national level. This study examines their status in the field, using the case of land grabbing on Padang Island, Riau Province, Indonesia. The findings include the company’s continued practice of purchasing land areas from local people at a lower price, not as compensation, because the company has not yet recognised the customary land rights. However, the local people contest the negotiation for a higher price through the newly introduced transparent practice of land transactions, involving village officers. The recommendation by the Mediation team to respect customary land rights is thus still a work in progress.