We study the weak convergence of the extremes of supercritical branching Lévy processes $\{\mathbb{X}_t, t \ge0\}$ whose spatial motions are Lévy processes with regularly varying tails. The result is drastically different from the case of branching Brownian motions. We prove that, when properly renormalized, $\mathbb{X}_t$ converges weakly. As a consequence, we obtain a limit theorem for the order statistics of $\mathbb{X}_t$.

Electronic measurement systems in the THz frequency range are often bulky and expensive devices. While some compact single-chip systems operating in the high millimeter-wave frequency range have recently been published, compact measurement systems in the low THz frequency range are still rare. The emergence of new silicon-germanium (SiGe) semiconductor technologies allow the integration of system components, like oscillators, frequency multipliers, frequency dividers, and antennas, operating in the low THz frequency range, into a compact monolithic microwave integrated circuits (MMIC), which contains most components to implement a low-cost and compact frequency-modulated continuous-wave-radar transceiver. This article presents a single transceiver solution containing all necessary components. It introduces a $0.48\,\mathrm{THz}$ radar transceiver MMIC with a tuning range of $43\,\mathrm{GHz}$ and an output power of up to $-9.4\,\mathrm{dBm}$ in the SG13G3 $130\,\mathrm{nm}$ SiGe technology by IHP. The MMIC is complemented by a dielectric lens antenna design consisting of polytetrafluoroethylene, providing up to $39.3\,\mathrm d\mathrm B\mathrm i$ of directivity and half-power beam widths of 0.95∘ in transmit and receive direction. The suppression of clutter from unwanted targets deviating from antenna boresight more than 6∘ is higher than $24.6\,\mathrm d \mathrm B$ in E- and H-Plane.

Alzheimer’s disease (AD) is a neurodegenerative disorder that accounts for 60%–70% of patients with dementia, and it is estimated that over one million Canadians will be living with dementia by 2030. Disease-modifying therapies (DMTs) targeting the underlying pathophysiology of AD are currently in development. Several models have demonstrated that the potential arrival of Alzheimer’s DMTs will most likely overwhelm the already-constrained Canadian healthcare system. Canada does not have a strategy to address the extensive requirements of using DMTs, including providing an early diagnosis of AD, confirming DMT eligibility via amyloid biomarkers, and conducting ongoing treatment monitoring. Thus, a multidisciplinary group of experts involved in AD care in Canada gathered to review (1) the current barriers to diagnosis and management of AD; (2) how existing clinic models, including those used in multiple sclerosis (MS), could be applied to address key barriers in AD; and (3) how to design and implement optimal care pathways in the future. The actions outlined in this review will help clinicians and healthcare systems improve readiness to integrate the use of disease-modifying therapies in Alzheimer’s disease, if such therapies are approved in Canada.

What is it like to be a partisan? How do individuals experience their relationship to political parties? The most common answer today, both in popular discourse and much political science, is identity, but many individuals do not identify with parties. Rather, they relate to parties in terms of psychological closeness or affinity—they do not say “we” about the party, as do identifiers, but rather “they.” In this article, I argue that both the empirical and normative study of partisanship would be improved by recognizing that these are two fundamentally different ways for individuals to be attached to parties and that these distinct experiences coexist within most democracies today. Acknowledging this basic plurality of partisanships would remedy the current tendency among empirical studies to homogenize partisanship as either identity or closeness and so would avoid falsifying the experience of many citizens who fall into the opposite category. In polarized contexts, moreover, it could help break up dualistic and antagonistic thinking about how to perform partisanship and diversify public understandings of how to be a partisan. Recognizing the plurality of partisanships would also improve the explosion of normative theorizing about partisanship found in the ground-breaking work of scholars like Nancy Rosenblum, Russell Muirhead, and Jonathan White and Lea Ypi. I show how identity and closeness partisanship—and the interaction between them—have transformative consequences for each of these scholars’ theories of partisanship, either furthering or threatening them. The article aims to improve the conceptualization of partisanship and to model a salutary engagement between normative and empirical inquiry within political science.

Maternal diet influences breast milk nutritional profile; however, it is unclear which nutrients and contaminants are particularly responsive to short- and long-term changes in maternal intake, and the impact of specific exclusion diets, such as vegan or vegetarian. This study systematically reviewed the literature on the effects of maternal nutrient intake, including exclusion diets, on both the nutrient and contaminant content of breast milk. The electronic databases, PubMed, CENTRAL, Web of Science and CINALH were systematically searched until 4 June 2023, with additionally searches of reference lists (PROSPERO, CRD42020221577). The quality of the studies was examined using Cochrane Risk of Bias tool and Newcastle–Ottawa scale. Eighty-eight studies (n 6577) met the search criteria. Due to high heterogeneity, meta-analysis was not possible. There was strong evidence of response to maternal intakes for DHA and EPA, vitamins A, E and K, iodine and Se in breast milk composition, some evidence of response for α-linolenic acid, B vitamins, vitamin C and D, ovalbumin, tyrosine and contaminants, and insufficient evidence to identify the effects arachidonic acid, Cu, Fe, Zn and choline. The paucity of evidence and high heterogeneity among studies reflects the need for more high-quality trials. However, this review identified the importance of maternal intake in the nutritional content of breast milk for a wide range of nutrients and supports the recommendation for supplementation of DHA and vitamin B12 for those on restrictive diets.

I focus on an overlooked aspect of the challenge of irrelevant influences. The challenge is often framed in terms of whether recognizing the presence of irrelevant factors in the pedigree of a belief provides a defeater. I argue that the epistemic significance of irrelevant factors goes beyond their status as defeaters. I focus on what I call gray cases, where learning about such factors causes epistemic worry without justifying giving up the belief. I argue that in gray cases, the subject finds a commendatory epistemic practical reason to engage in an activity intended to assuage that epistemic worry.

Analysis of the chronological data and observation of a lagoonal sediment core reveal sand washover events between around 2.4 to 2.5 cal. ky BP in the Isumi River lowland. We conducted radiocarbon dating with AMS and constructed an age-depth model using the latest calibration curve and appropriate model routine. In the middle to lower part of the core, dark-gray sand layers are repeatedly deposited. Sand layers may exhibit an erosional surface at the base with fining upward grading. The overwash layers are composed of well-rounded sand with occasional gravel, indicative of transportation. overwash sediment characteristics are consistent with proximal marine deposits, suggesting an ocean origin (though riverine sediment is also similar in character). The age-depth model indicates very high sediment accumulation rates associated with overwash deposits. Based on the amount of accumulated sediment, relatively large-scale redeposition events occurred during this period but more information is needed to constrain the mechanism(s) causing the events. We also present a local reservoir age correction compatible with the Marine20 calibration curve.

Let G be a compact quantum group. We show that given a G-equivariant $\textrm {C}^*$-correspondence E, the Pimsner algebra $\mathcal {O}_E$ can be naturally made into a G-$\textrm {C}^*$-algebra. We also provide sufficient conditions under which it is guaranteed that a G-action on the Pimsner algebra $\mathcal {O}_E$ arises in this way, in a suitable precise sense. When G is of Kac type, a KMS state on the Pimsner algebra, arising from a quasi-free dynamics, is G-equivariant if and only if the tracial state obtained from restricting it to the coefficient algebra is G-equivariant, under a natural condition. We apply these results to the situation when the $\textrm {C}^*$-correspondence is obtained from a finite, directed graph and draw various conclusions on the quantum automorphism groups of such graphs, both in the sense of Banica and Bichon.

The actin filaments on the surface of echinoderm oocytes and eggs readily undergo massive reorganization during meiotic maturation and fertilization. In sea urchin eggs, the actin cytoskeletal response to the fertilizing sperm is fast enough to accompany Ca2+ signals and to guide sperm’s entry into the egg. Although recent work using live cell imaging technology confirmed changes in the actin polymerization status in fertilized eggs, as was previously shown using light and electron microscopy, it failed to provide experimental evidence of F-actin depolymerization a few seconds after insemination, which is concurrent with the sperm-induced Ca2+ release. In the present study, we applied Raman microspectroscopy to tackle this issue by examining the spectral profiles of the egg’s subplasmalemmal regions before and after treating the eggs with actin drugs or fertilizing sperm. At both early (15 s) and late (15 min) time points after fertilization, specific peak shifts in the Raman spectra revealed change in the actin structure, and Raman imaging detected the cytoskeletal changes corresponding to the F-actin reorganization visualized with LifeAct-GFP in confocal microscopy. Our observation suggests that the application of Raman spectroscopy, which does not require microinjection of fluorescent probes and exogenous gene expression, may serve as an alternative or even advantageous method in disclosing rapid subtle changes in the subplasmalemmal actin cytoskeleton that are difficult to resolve.

The article provides experimental evidence of the effect of candidate-citizen town-hall meetings on voters’ political behavior. The intervention took place prior to the March 2011 elections in Benin and involved 150 randomly selected villages. In the treatment group, candidates held town-hall meetings where voters deliberated over their electoral platforms. The control group was exposed to the standard campaign—that is, one-way communication of the candidate’s platform by himself or his local broker. We find that town-hall meetings led to a more informed citizenry and higher electoral participation, which diverged little along socioeconomic lines. We also observe a lower effectiveness of vote-buying attempts where town halls took place. This is consistent with town-hall deliberation promoting what we call more “ethical” voters.

In this article, we show that statements of U.S. CEOs on contentious social issues are not necessarily an expression of their political views. Republican-donor CEOs are three times more likely to make social statements with a liberal slant. CEO activism is more likely if firms’ operating environment is politically polarized and employees are Democrat-leaning. Such statements are associated with a 3% increase in consumer visits to a firm’s Democrat County stores without significantly reducing them in Republican counties. CEO activism is associated with a 0.12% gain in firm value, increased quarterly sales, and a reduced likelihood of shareholder activism on social issues.