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Ziziphus lotus is an underappreciated natural genetic resource widespread in Algeria. This study aimed to compare the fruit phytochemical composition of nine populations of Z. lotus from different areas to highlight its diversity. Fruits were harvested from the semiarid, dry steppe and Saharan stages. Primary and secondary metabolites and minerals contents were determined. Significant variations in the fruit phytochemical composition between populations of Z. lotus and between pulp and seeds were recorded. Z. lotus is dry fruit with 8.768 ± 0.449 to 13.468 ± 1.303% water in pulp and 6.7 to 12.12% in seeds. Significantly higher values were recorded in the fruit pulp for sugar (35.25 to 48.87%), phosphorus (63.114 to 155.269 mg 100−1g), sodium (34.8 to 56.91 ppm), calcium (91.78 to 382.69 ppm), β-carotene (36.4 to 46 μg g−1), lycopene (59.15 to 100.25 μg g−1) and chlorophyll a (3.6 to 7.2 μg g−1) contents. Seeds had much higher protein (8.37 to 27.75%), lipid (35.39 to 48.01%), potassium (125.874 to 325.408 mg. 100−1 g), polyphenol (439.465 to 1349.46 mg.GAE.100 g−1), flavonoid (83.908 to 98.259 mg.QE.100 g−1), tannins (55.268 to 277.94 mg.GAE.100 g−1) and chlorophyll b (11.2 to 30.4 μg g−1) contents. Bougtob, Boghar and Mougheul populations had higher primary metabolites and mineral values. Oued Nougued, Maarif and Mougheul populations were the richest in phenolic compounds. Oued Nougued, Maarif and Mougheul populations had more liposoluble pigments. This research is the beginning of investigating the variety of Z. lotus as phylogenetic sources. Further comparative investigations over a larger distribution region and further study of variations in the composition in fruit composition using GC-MS are needed.
We develop and analyse a continuum model of two-phase slurry dynamics for planetary cores. Mixed solid–liquid slurry regions may be ubiquitous in the upper cores of small terrestrial bodies and have also been invoked to explain anomalous seismic structure in the F-layer at the base of Earth's liquid iron core. These layers are expected to influence the dynamics and evolution of planetary cores, including their capacity to generate global magnetic fields; however, to date, models of two-phase regions in planetary cores have largely ignored the complex fluid dynamics that arises from interactions between phases. As an initial application of our model, and to focus on fundamental fluid dynamical processes, we consider a non-rotating and non-magnetic slurry comprised of a single chemical component with a temperature that is tied to the liquidus. We study one-dimensional solutions in a configuration set up to mimic Earth's F-layer, varying gravitational strength $R$, the solid/liquid viscosity ratio $\lambda _{\mu }$ and the interaction parameter $K$, which measures friction between the phases. We develop scalings describing behaviour in the limit $R \gg 1$ and $\lambda _{\mu } \gg 1$, which are in excellent agreement with our numerical results. Application to Earth's core, where $R \sim 10^{28}$ and $\lambda _{\mu } \sim 10^{22}$, suggests that a pure iron slurry F-layer would contain a mean solid fraction of at most 5 %.
Rereading Toni Morrison’s novel Beloved, this article explores how Morrison’s work at the limits of language performs the haunting ties between the Reconstruction era and the present day by offering readers a way to experience a rememory of their own. By repeatedly emphasizing the inadequacy of language in expressing traumatic experience, Beloved encourages its readers to, like its characters, look beyond language and seek out a kind of ineffable, embodied knowledge to better understand the lingering traumas of slavery. Through Morrison’s concept of “invisible ink,” which points to the inevitability that lived experience cannot be captured in language by the author alone but must be filled in by an active reader, this article makes a larger argument: that Beloved acts as both an invitation and a guide to read the ghostly, invisible ink of history that exists outside the novel, haunting our world itself.
The past decade has been a difficult time to be a scholar of Chinese politics. After Xi Jinping came to power in 2012, opportunities for international collaboration began disappearing, and local interlocutors became increasingly nervous about speaking with foreign researchers. Since 2016, these problems have been compounded by the increasingly tense US–China relationship. Changing attitudes and policies in both countries have hindered those who conduct research on China, work with Chinese collaborators, and recruit Chinese students. The Fulbright Program in China and Hong Kong was closed; National Institutes of Health investigations into foreign influence in US science have caused US-based scientists’ research productivity to decline; and visa restrictions have hindered efforts to recruit Chinese graduate students (Jia et al. 2023). Legal changes in China, including the 2021 Personal Information Protection Law and the 2023 revised Counter-Espionage Law, could be used to target foreign scholars who conduct research in China (Lewis 2023; McCarthy and Gan 2023). The COVID-19 pandemic compounded these challenges in several ways: it caused a rise in anti-Chinese sentiment in the United States and created severe pedagogical challenges for those teaching Chinese politics and other courses containing “sensitive” material that could put students—some now physically located in China—at risk (Gueorguiev et al. 2020).
Interest groups and policy advocates often view the initiative process as a way to circumvent a gridlocked state legislative process. A major assumption behind this strategy is that this alternative path can be successful. We theorize that the same conflict and lack of consensus that killed the legislation in the legislative process may resurface in the electorate and jeopardize the measure’s chances of success at the ballot box. We test this proposition on all initiatives in California from 1912 to 2020 and on a smaller subset of the data that controls for campaign spending and the economy. We find clear and consistent evidence that voter support for initiatives, especially fiscal initiatives, declines under periods of divided government. In addition, interactive models show that increasing levels of party polarization exacerbate these effects. We conclude by discussing the implications of these results for the debate about whether the initiative process makes states more responsive to constituent opinion.
During the past century, protest has become a shared experience around the world, as citizens across the continents have taken to the streets to demand political, social, and economic changes. In Asia—from China to India, Thailand to Myanmar—people have organized mass demonstrations to express their dissatisfaction with colonial and state governments and their policies. Often, people shared news and supported protests in neighboring countries, using it as an opportunity to mobilize and coordinate their efforts for protest and leading to a growing sense of regional solidarity. Solidarity is possible despite differences in culture, history, and language because the citizens in the region share universal values.
We obtain an optimal actuation waveform for fast synchronization of periodic airfoil wakes through the phase reduction approach. Using the phase reduction approach for periodic wake flows, the spatial sensitivity fields with respect to the phase of the vortex shedding are obtained. The phase sensitivity fields can uncover the synchronization properties in the presence of periodic actuation. This study seeks a periodic actuation waveform using phase-based analysis to minimize the time for synchronization to modify the wake shedding frequency of NACA0012 airfoil wakes. This fast synchronization waveform is obtained theoretically from the phase sensitivity function by casting an optimization problem. The obtained optimal actuation waveform becomes increasingly non-sinusoidal for higher angles of attack. Actuation based on the obtained waveform achieves rapid synchronization within as low as two vortex shedding cycles irrespective of the forcing frequency, whereas traditional sinusoidal actuation requires ${O}(10)$ shedding cycles. Further, we analyse the influence of actuation frequency on the vortex shedding and the aerodynamic coefficients using force-element analysis. The present analysis provides an efficient way to modify the vortex lock-on properties in a transient manner with applications to fluid–structure interactions and unsteady flow control.
What do the provisions on the non-discrimination principle (the principles) in digital trade mean under trade agreements, especially in the absence of a clear international consensus on the subject of the principles? To answer this question, this study first identifies the issues related to the application of the principles in digital trade and presents a theoretical framework to explain how the principles can affect digital trade despite such issues. Using various data sources, such as digital trade flows, the inclusion of the principles in digital trade agreements, and digital trade barriers, we empirically test the hypotheses constructed from our theoretical framework. We find that inclusion of the principles in the trade agreements is more likely to increase digital trade flows. Moreover, though digital trade barriers decrease digital trade flows, this negative effect can be mitigated when the principles are more clearly defined in the trade agreements.
Canadian neurology residency programs recently transitioned to Competency-Based Medical Education (CBME). Iterative evaluation is required to optimize CBME implementation. This study aimed to examine the variability and challenges in uptake of CBME in neurology residency programs and identify its benefits and pitfalls. Neurology residents and faculty participated in respective anonymous surveys. Common barriers to uptake were identified from both perspectives. Orientation to CBME was adequate, but workload was increased and contributed to burnout for faculty and residents. It is premature to draw conclusions regarding benefits of CBME. Future research considerations include standardization of entrustment scales and reduction of stakeholder burden.
This article analyses the scientific and ideological impact of the 1951 tick-borne encephalitis epidemic in Rožňava (Czechoslovakia). Scientists in Rožňava discovered the possibility of transmission of the tick-borne encephalitis virus through non-pasteurised milk. The article focuses on both the outbreak in Rožňava, with its social and ideological implications, and the subsequent virological research, which became a means of prestige and symbolic power for Czechoslovak scientists within the domestic and international scientific community. The article shows that an epidemic can become a tool of power. The Rožňava epidemic, although now forgotten, helped establish the institutional background for virological research in Czechoslovakia and was at the origin of the still cutting-edge knowledge of tick-borne encephalitis.
Shareholder say-on-pay voting allows institutional investors to influence the incentives of managers and, consequently, corporate behaviour. Surprisingly, the preferences of investors on executive compensation have been largely overlooked in the ongoing debates on the role of say-on-pay in corporate governance and the impact of shareholder stewardship on sustainable corporate behaviour. The analysis of investor disclosed explanations of say-on-pay votes in the FTSE 100 companies during 2013–2021 shows that institutional investors rely repeatedly on several dominant themes aimed at improving the incentives of corporate managers and controlling managerial rent extraction. But shareholder interests remain the core focus of say-on-pay votes, with only few investors demanding that companies reward executive directors for protecting the interests of a broader range of affected stakeholders. Additionally, most investors can be grouped into several clusters formed around the voting recommendations of proxy advisers. A group of UK-based institutional investors stands out by taking a more individualistic and diverse approach to the stewardship of executive compensation. These findings highlight the role of local investors in the oversight of executive pay, the growing influence of proxy advisers along with the increasing share of foreign institutional investors, and the influence of best practice governance codes in driving investor stewardship preferences.
The Palaearctic ten-spotted lady beetle, Adalia decempunctata (Linnaeus), has been confirmed as established in North America, based on morphological characters and DNA barcodes. Its distribution currently appears limited to the Avalon Peninsula of the island of Newfoundland, Canada. Several characters, including the colour of the mesepimera, frons, labrum, antennal club, mouthparts, and legs, are reliable for discriminating among this species and the native, Holarctic two-spotted lady beetle, Adalia bipunctata (Linnaeus), in Newfoundland. An identification key to the two species is provided.
Early life is a sensitive period when microbiota-gut-brain interactions may have important impact on development. This study investigated the associations of the gut microbiota in the first three years of life (two, six, and 12 weeks, and one and three years) with problem behavior and executive functions in N = 64 three-year-old children. Higher relative abundance of Streptococcus at the age of two weeks, as well as its trajectory over time (including ages two, six and 12 weeks, and one and three years), was related to worse executive functions. Higher relative abundance of [Ruminococcus] torques group at the age of three years, as well as its trajectory from one to three years, was associated with less internalizing behavior. Besides, several robust age-specific associations were identified: higher Bifidobacterium relative abundance (age three years) was associated with more internalizing and externalizing issues; higher Blautia relative abundance (age three years) was linked to less internalizing behavior; and increased relative abundance of an unidentified Enterobacteriaceae genus (age two weeks) was related to more externalizing behavior. Our findings provide important longitudinal evidence that early-life gut microbiota may be linked to behavioral and cognitive development in low-risk children.
I provide simplified proofs for each of the following fundamental theorems regarding selection principles:
(1) The Quasinormal Convergence Theorem, due to the author and Zdomskyy, asserting that a certain, important property of the space of continuous functions on a space is actually preserved by Borel images of that space.
(2) The Scheepers Diagram Last Theorem, due to Peng, completing all provable implications in the diagram.
(3) The Menger Game Theorem, due to Telgársky, determining when Bob has a winning strategy in the game version of Menger’s covering property.
(4) A lower bound on the additivity of Rothberger’s covering property, due to Carlson.
The simplified proofs lead to several new results.