Ten-day-old neonate who underwent correction of interrupted aortic arch developed a giant early post-surgical aneurysm. To our knowledge, this unusual complication has been only reported as a late complication.

The recent recovery of the teaching that the three divine persons share one operation in their outward works raises the question of whether or in what sense the human operation of Christ belongs to the Son alone. My thesis is that all three divine persons move and support the Son's human operation while the Son alone is the proper subject of his human operation. In order to substantiate this thesis, I will consider two main issues: (1) the relationship between divine movement and human energy and (2) the relationship between nature and person in Christ's human action.

The onset of COVID-19 was characterized by voluminous, negative news. Higher narrativity news topics (measured by textual proximity to articles describing the 1987 stock market crash and textual distance from Federal Reserve communications) were systematically associated with contemporaneous market responses, which were larger on high volatility days (hypersensitivity), and with markets–news feedback. Hypersensitive news topic-market pairs were associated with next-day reversals. A test using the news–markets relationship identifies a mid-March 2020 structural break, which was knowable by the end of April. Post break, markets and news became considerably less coupled, and hypersensitivity and reversals abated.

Investigating trophic linkages sustaining consumers is crucial to understanding their functional ecological role in communities and ecosystems. In this work, we combined stomach content (SCA) and stable isotope (SIA) analyses to investigate the trophic ecology of the Plata pompano Trachinotus marginatus during a critical phase of its life cycle along a subtropical sandy beach. This species is a conspicuous component of the southwestern Atlantic coast and commonly targeted by coastal fisheries. The diet was described using SCA, whereas the relative importance of food sources sustaining juveniles, as well their food niche structure and trophic position (TP), were evaluated using SIA. Juveniles consumed mainly crustaceans like the hippid crab Emerita brasiliensis, although other invertebrates (annelids, insects, molluscs) and fishes (including cannibalism) were also recorded. Although microcrustaceans dominated the diet, SIA showed that more palatable preys without carapaces or shells, like fishes and annelids, were the most assimilated preys in the muscle tissue of juvenile T. marginatus. There were marked changes in their isotopic niches (SEAc) and TP across ontogeny. SEAc ranged from 1.41‰2 for smaller individuals (0–40 TL mm) to 0.3‰2 for larger individuals (>80 TL mm). TP ranged from 3.1 (95% CI 2.7–3.6) for smaller to 4.5 (95% CI 3.9–5.1) for larger individuals. SIA suggest that juvenile T. marginatus derived most of their primary nutrients from a planktonic food web and, to a lesser extent, from a benthic pathway. Future studies are needed to better understand its functional role in food web of surf-zone ecosystems.

Can autocratic policy generate incentives for the accumulation of social capital and political engagement? This question is important to understand stability in authoritarian regimes that increasingly rely on governance to build legitimacy and social support. While existing research shows that the incentives for societal interaction embedded in policies can yield new forms of social capital and political engagement in democratic regimes, the top-down nature of policy and the corrupt and information-poor context of policy implementation could undermine this mechanism in authoritarian regimes. We explore this question by examining the effect of the Moscow Housing Renovation Program, a massive urban renewal project, that required residents to organize to obtain new housing. Comparing a matched sample of 1,300 residents living in buildings included and excluded from the program, we find that interactions induced by the program led to changes in the level of social capital among residents in included buildings. We also find spillover effects on political engagement and collective action against pension reform.

This article interrogates the scientific conference as a means by which the organizers of the World League for Sexual Reform's 1929 conference attempted to marshal the ‘scientific spirit’ in order to present progressive sexual reform as a rational and scientifically informed undertaking. The conference was carefully curated to make the sex reform movement (and the assorted characters that gathered under its banner) look serious, legitimate and, most importantly, scientific. The conference was also an attempt by organizer Norman Haire to exert control over the strategy of sexology, an enterprise that put him at odds with other prominent sexologists of the time. Crucially, Haire understood sexology as inherently intellectually interdisciplinary, but was strategically convinced that the only sound rubric through which to promote and gain acceptance for the movement was through medical science. This central debate, about how best to define the contested concept of sexology, continues among historians today. By examining how the 1929 conference organizers wrestled to define their sex-reforming remit and how they curated the conference to that end, this paper will offer a window onto the mechanisms via which adherents of intellectual communities contend with heterogeneity, how we judge forms of knowledge and, ultimately, what constitutes science.

The endomorphism monoid of a model-theoretic structure carries two interesting topologies: on the one hand, the topology of pointwise convergence induced externally by the action of the endomorphisms on the domain via evaluation; on the other hand, the Zariski topology induced within the monoid by (non-)solutions to equations. For all concrete endomorphism monoids of $\omega $-categorical structures on which the Zariski topology has been analysed thus far, the two topologies were shown to coincide, in turn yielding that the pointwise topology is the coarsest Hausdorff semigroup topology on those endomorphism monoids.

We establish two systematic reasons for the two topologies to agree, formulated in terms of the model-complete core of the structure. Further, we give an example of an $\omega $-categorical structure on whose endomorphism monoid the topology of pointwise convergence and the Zariski topology differ, answering a question of Elliott, Jonušas, Mitchell, Péresse, and Pinsker.

Let $\Gamma \subset \overline {\mathbb {Q}}^*$ be a finitely generated subgroup. Denote by $\Gamma _{\mathrm {div}}$ its division group. A recent conjecture due to Rémond, related to the Zilber–Pink conjecture, predicts that the absolute logarithmic Weil height of an element of $\mathbb {Q}(\Gamma _{\mathrm {div}})^*\backslash \Gamma _{\mathrm {div}}$ is bounded from below by a positive constant depending only on $\Gamma $. In this paper, we propose a new way to tackle this problem.

Local governments have been increasingly active in immigration policy by cooperating with federal immigration enforcement or creating local offices of immigrant affairs (OIA) charged with integrating immigrants. How do these policies shape perceptions of locales following these policy routes? Using a set of pre-registered survey experiments, we find that compared to local cooperation with federal immigration enforcement, creating an OIA produces more favorable public attitudes, with minimal differences when undocumented immigrants also receive access to services. Democrats, especially white Democrats, have the most favorable views of cities with an OIA. While Republicans prefer cooperation with ICE, their attitudes toward cities with OIAs remain positive. Our findings suggest that despite partisan polarizing immigration policy debates, establishing OIAs does not attract the negative political attention common in an era of hyperpolarization. OIAs could be a rare immigration policy that may be effective and supported.

This essay discusses how, for Hegel, freedom can be realized in nature in a rudimentary fashion in solar systems. This solves a problem in Kant's account of freedom, namely, the problem that Kant only gives a negative argument for why freedom is not impossible but does not give a positive account of how freedom is real. I give a novel account of Kant's negative argument. Then, I show how, according to Hegel, solar systems can be considered as exhibiting freedom in a rudimentary fashion. Finally, I lay out how Hegel systematically develops this point about the freedom of solar systems in the ‘Mechanism’ chapter of the Science of Logic. In doing so, he uses Kant's negative argument in a ‘purified’ form to arrive at an account of an ‘intimate token-type relation’ between the planets in a solar system and the law that governs their motion. The essay as a whole provides a concrete example of how Hegel is an inheritor and radicalizer of Kant, both with respect to freedom's reality and with respect to philosophical method.

Childhood adversity represents a robust risk factor for the development of harmful substance use. Although a range of empirical studies have examined the consequences of multiple forms of adversity (i.e., childhood maltreatment, parental alcohol use disorder [AUD]), there is a dearth of information on the relative effects of each form of adversity when considered simultaneously. The current study utilizes structural equation modeling to investigate three unique and amplifying pathways from parental AUD and maltreatment exposure to offspring alcohol use as emerging adults: (1) childhood externalizing symptomatology, (2) internalizing symptomatology, and (3) affiliation with substance-using peers and siblings. Participants (N = 422) were drawn from a longitudinal follow-up study of emerging adults who participated in a research summer camp program as children. Wave 1 of the study included 674 school-aged children with and without maltreatment histories. Results indicated that chronic maltreatment, over and above the effect of parent AUD, was uniquely associated with greater childhood conduct problems and depressive symptomatology. Mother alcohol dependence was uniquely associated with greater affiliation with substance-using peers and siblings, which in turn predicted greater alcohol use as emerging adults. Results support peer and sibling affiliation as a key mechanism in the intergenerational transmission of substance use between mothers and offspring.

Klotho is a protein that plays different functions in female fertility. We have previously reported that klotho protein supplementation during in vitro maturation improves porcine embryo development, while klotho knockout for somatic cell cloning completely blocks full-term pregnancy in vivo. However, the effects of the microinjection of klotho protein or klotho knockdown dual vector in porcine embryos at different time points and the specific molecular mechanisms remain largely unknown. In this study, we injected the preassembled cas9 + sgRNA dual vector, for klotho knockdown, into the cytoplasm of the germinal vesicle stage of oocytes and into porcine embryos after 6-h parthenogenetic activation. Similarly, the klotho protein was inserted into the cytoplasm of germinal vesicle stage oocytes and porcine embryos after 6-h parthenogenetic activation. Compared with the controls, the microinjection of klotho dual vector markedly decreased the blastocyst formation rates in germinal vesicle stage oocytes and activated embryos. However, the efficiency of blastocyst formation when klotho protein was inserted before in vitro maturation was significantly higher than that after klotho protein insertion into parthenogenetically activated embryos. These results indicated that klotho knockdown may impair embryo development into blastocyst irrespective of injection timing. In addition, klotho protein injection timing in pig embryos may be an important factor for regulating embryo development.

Globally, diet quality is poor, with populations failing to achieve national dietary guidelines. Such failure has been consistently linked with malnutrition and poorer health outcomes. In addition to the impact of diet on health outcomes, it is now accepted that what we eat, and the resulting food system, has significant environmental or planetary health impacts. Changes are required to our food systems to reduce these impacts and mitigate the impact of climate change on our food supply. Given the complexity of the interactions between climate change, food and health, and the different actors and drivers that influence these, a systems-thinking approach to capture such complexity is essential. Such an approach will help address the challenges set by the UN 2030 Agenda for sustainable development in the form of the sustainable development goals (SDG). Progress against SDG has been challenging, with an ultimate target of 2030. While the scientific uncertainties regarding diet and public and planetary health need to be addressed, equal attention needs to be paid to the structures and systems, as there is a need for multi-level, coherent and sustained structural interventions and policies across the full food system/supply chain to effect behaviour change. Such systems-level change must always keep nutritional status, including impact on micronutrient status, in mind. However, benefits to both population and environmental health could be expected from achieving dietary behaviour change towards more sustainable diets.