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This study revisits the V3 linearization AdvP>Subject>finite verb in Kiezdeutsch, comparing it to resumptive verb-third Left Dislocation and Hanging Topic Left Dislocation. Using corpus data, preverbal object DPs are shown to almost never occur across verb-third distributions, yet preverbal nominative subjects and spatio-temporal elements are unproblematic. This behavior is argued to involve a low C-domain position encoding a Subject of Predication requirement (see Cardinaletti 2004) tied to aboutness and nominative Case-assigning features, but not a strict D-related subject EPP. Based on comparison with other corpora and analysis of metadata, speakers from non-German-speaking homes, namely successive bilinguals, are argued to have innovated this property. A novel account is suggested for the emergence of V3 based on claims that it results from a natural informational order (Wiese et al. 2020), which is formalized as a Minimal Default Grammar (Roeper 1999) available to children before they fully acquire CP and TP. Children acquiring a V2 language must either reject V3 or incorporate it into a V2 syntax. Lacking adequate counterevidence in their input, Kiezdeutsch speakers do the latter.*
Entomophagy (eating edible insects) could potentially address human deficiencies of iron, zinc and vitamin B12. This article aims to summarise available evidence about the iron, zinc and vitamin B12 content of raw and processed edible insects and compare these with the nutritional needs of different human life stages. A systematic literature search using specific keywords (edible insects, iron content, zinc content, vitamin B12 content and nutritional composition) in Web of Science and Scopus databases was performed. Forty-six studies were reviewed. To ensure standardised comparisons, articles with nutrient-enriched edible insects were excluded. The quality of records was assessed using standardised protocols. Results indicate that edible insects are generally either ‘sources of’ or ‘rich in’ iron, zinc and vitamin B12 required for optimal nutrition and health of different human life stages. Moreover, iron, zinc and vitamin B12 contents of edible insect species were generally either comparable to or higher than that of (lean) beef, (lean) pork, poultry and kidney beans. Most insect species were oven processed with little/no species-specific data for other processing methods. Variations in micronutrient content existed between processing methods and among oven-processed edible insects. Data inaccuracies, poor data quality control and lack of insect-specific official analytical methods contributed to fairly high variations and made comparisons difficult. Based on available data, edible insects can potentially address human deficiencies of iron, zinc and vitamin B12 despite the observed variations, data gaps and lack of edible insect matrix-specific official methods, in addition to limited human bioavailability and efficacy studies.
Increase bleeding control knowledge and self-efficacy among middle school students and determine efficacy of health care student-led Stop the Bleed (STB) training.
Methods
An interprofessional group of health care students led STB trainings at 6 Texas middle schools. Trainings included a presentation plus hands-on skills training and were evaluated using pre- and post-training surveys focused on bleeding control knowledge, self-efficacy, and willingness to assist in emergencies. Paired pre- and post-training survey responses were compared using McNemar’s test for knowledge-based questions and paired t tests for Likert scale responses.
Results
Health care students (N = 103) trained 805 middle school students, aged 10-16 years, of which 447 (55.5%) completed pre- and post-surveys. There was significant improvement in all 7 knowledge-based questions from pre- to post-training. There were significant improvements in comfort using tourniquets (median [interquartile range]: 3 [2-4] vs. 4 [3-5]; P < 0.0001), confidence applying direct pressure (3 [2-4] vs. 4 [3-5]; P < 0.0001), and likeliness to assist someone bleeding (4 [3-5] vs. 4 [4-5]; P = 0.0096). Eighty-four percent of students found this training “useful.”
Conclusions
While previous studies have demonstrated STB training efficacy, this is among the first to provide evidence that health care student-led STB training significantly increased bleeding control knowledge and self-efficacy among middle school students.
Jubilees are good to think with, obviously. They provide a fitting opportunity to look back, to take stock, and to offer some thoughts about the future. As a scholar working on Byzantine history (and only slightly older than BMGS at that) I recognize that the state of the field has changed immensely in the last fifty years. First, there was a major expansion in departments and programmes dedicated to Byzantine studies, followed more recently by a contraction. And yet, even while Byzantine studies are offered in fewer academic institutions, there is an immense proliferation of academic research and publications on the Byzantine Empire – trend accelerating. Exact numbers may be hard to come by, but a quick search on WorldCat for books published in 2023 with the word ‘Byzantine’ in the title brought forth almost two hundred books – in English alone. If we add journal articles (there are over twenty major journals devoted solely to Byzantine studies), chapters in edited volumes, and, especially publications in languages other than English, we would probably reach the low thousands, all in one year. To survey, much less to read with care and absorb all this new knowledge, has become impossible. How handy would it be if someone else took over this task for us – processing research and synthesizing it in a clear, concise and readable volume. It is highly doubtful that such a book could be produced today, but there is a work that fulfilled these functions for a very long time, one of the most cited and recommended textbooks in Byzantine history, Georg Ostrogorsky's History of the Byzantine State.
Self-harm, self-poisoning or self-injury, irrespective of the motivation, is a central risk factor for suicide. Still, there is limited knowledge of self-harm among patients with substance use disorders (SUDs) who die by suicide.
Aims
We aimed to describe the prevalence of a history of self-harm and identify the factors associated with self-harm, comparing individuals who died by suicide with and without SUDs.
Method
We used data from the Norwegian Surveillance System for Suicide in Mental Health and Substance Use Services, which is based on a national linkage between the Norwegian Cause of Death Registry and the Norwegian Patient Registry, to identify individuals who died by suicide within 1 year after last contact with mental health or substance use services (n = 1140). A questionnaire was retrieved for 1041 (91.3%) of these individuals. We used least absolute shrinkage and selection operator (LASSO) regression to select variables and compared patients with and without SUDs. Conditional selective inference was used to improve 90% confidence intervals and p-values.
Results
The prevalence of self-harm was 55% in patients with SUDs and 52.6% in patients without SUDs. Suicidal ideation (odds ratio 2.98 (95% CI 1.74–5.10)) emerged as a factor shared with patients without SUDs, while personality disorders (odds ratio 1.96 (1.12–3.40)) and a history of violence (odds ratio 1.86 (1.20–2.87)) were unique factors for patients with SUDs.
Conclusions
A history of self-harm is prevalent in patients with SUDs who die by suicide and is associated with suicidal ideation, a history of violence and personality disorders in patients with SUDs.
The Brahman sage Gautama cursed Indra with emasculation, in some versions through the appearance of vulvas on his body, as a punishment for intercourse with Gautama's wife, Ahalyā; Ahalyā's punishment involved detraction from her visible or physical presence. I present an analysis of the version as told in Padmapurāṇa 1.54. The story, in addition to reflecting male suspicion of women and dread of feminisation, simultaneously functions as a cautionary tale about the dangers of succumbing to lust and reflects inter-varṇa tension: the weak-willed Indra, a divine kṣatriya, is humiliated by the continent Gautama, whose asceticism is the source of the devastating power that he unleashes against both Indra and Ahalyā. I also compare this myth to the Greek tales of Achilles, Herakles, and Teiresias's feminisations, and suggest that the association of heroic feminisation with sexuality (as seen in the stories in which Indra, Achilles, and Herakles are feminised) may be a shared inheritance from Proto-Indo-European times. However, the myths of Achilles and Herakles's feminisations, like that of Indra's, are shaped by their specific cultural context: the feminised Greek heroes’ penetration of women is confirmation of their continued masculinity, rather than the result of a reprehensible lack of self-control.
Many influential political science articles use close elections to study how important outcomes vary after a certain type of candidate wins, such as a Democrat or a Republican. This politician characteristic regression discontinuity (PCRD) design offers opportunities for inferential leverage but also the potential for confusion. In this article, we clarify what causal claims the PCRD licenses, offering a rigorous causal analysis that points to three principal lessons. First, PCRDs do nothing to isolate the effect of the politician characteristic of interest as apart from other politician characteristics. Second, selection processes (regarding both “who runs” and “which elections are close”) can generate and exacerbate such confounding, as noted in Marshall (2024). Third and more fortunately, this approach does make it possible to estimate the average effect of electing a leader of type “A” vs. “B” in the context of close elections, treating the units as districts, not leaders. We also suggest a set of tools that can aid in falsifying key assumptions, avoiding unwarranted claims, and surfacing mechanisms of interest. We illustrate these issues and tools through a reanalysis of an influential study about what happens when extremists win primaries (Hall 2015).
Levetiracetam (LEV) is an antiseizure medication (ASM) used as a second line after benzodiazepines for status epilepticus treatment. Current literature lacks direct head-to-head comparisons between different LEV loading dose strategies, leading to uncertainty about superior dosing methods and thus clinical practice variations.
Methods:
A retrospective cohort study was designed to compare efficacy and safety of low (<30 mg/kg) versus high (≥30 mg/kg) weight-based LEV loading doses in adults with benzodiazepine-refractory status epilepticus (BRSE). The primary outcome of this study was termination of BRSE. No requirement for additional ASM after LEV was a surrogate for BRSE termination. Secondary endpoints included endotracheal intubation, intensive care unit (ICU) admission, 30-day all-cause mortality and adverse drug reactions. Statistical analysis included discrete and inferential statistics, including logistic regression and win-ratio analysis, to control for potential confounding variables.
Results:
Of the 106 patients included in this study, 54 (51%) did not require additional ASM after LEV, thereby achieving seizure termination. There was a higher proportion of patients with seizure termination in the higher weight-based dosing group as compared to the lower weight-based group (66% vs 40%, respectively; aOR 3.07; 95% CI: 1.36–7.21). There were lower rates for endotracheal intubation, ICU admission and all-cause mortality in the higher dosing group. Adverse events were comparable between the both groups.
Conclusion:
LEV’s high weight-based loading dose strategy (≥30 mg/kg) is more effective in the termination of BRSE as compared to the lower weight-based loading dose strategy (<30 mg/kg).
We present a family of minimal modal logics (namely, modal logics based on minimal propositional logic) corresponding each to a different classical modal logic. The minimal modal logics are defined based on their classical counterparts in two distinct ways: (1) via embedding into fusions of classical modal logics through a natural extension of the Gödel–Johansson translation of minimal logic into modal logic S4; (2) via extension to modal logics of the multi- vs. single-succedent correspondence of sequent calculi for classical and minimal logic. We show that, despite being mutually independent, the two methods turn out to be equivalent for a wide class of modal systems. Moreover, we compare the resulting minimal version of K with the constructive modal logic CK studied in the literature, displaying tight relations among the two systems. Based on these relations, we also define a constructive correspondent for each minimal system, thus obtaining a family of constructive modal logics which includes CK as well as other constructive modal logics studied in the literature.
Photographs are seldom at the centre of Greek historical research, despite their frequent use as illustrations. Despite this neglect of photography, modern Greek history would seem unimaginable without photographs, highlighting photography's integral role in our thinking about the past. In this article I offer some theoretical reflections on the impact of photography on historical imagination. Thereafter I take a closer look at some examples that do consider photography's role in the practice of Greek history, showing how photographs have been both mistrusted and embraced in historical research.
In today’s insurance market, numerous cyber insurance products provide bundled coverage for losses resulting from different cyber events, including data breaches and ransomware attacks. Every category of incident has its own specific coverage limit and deductible. Although this gives prospective cyber insurance buyers more flexibility in customizing the coverage and better manages the risk exposures of sellers, it complicates the decision-making process in determining the optimal amount of risks to retain and transfer for both parties. This article aims to build an economic foundation for these incident-specific cyber insurance products with a focus on how incident-specific indemnities should be designed for achieving Pareto optimality for both the insurance seller and the buyer. Real data on cyber incidents are used to illustrate the feasibility of this approach. Several implementation improvement methods for practicality are also discussed.
Archaeological excavations conducted during the construction of the Museum of the Acropolis in Athens exposed an urban neighbourhood dated from the classical to the Byzantine periods. This discovery induced a modification of the original architectural plan: museum and excavation were combined into a unique exhibition ensemble. Its visitors further created another, peculiar and makeshift, spatial innovation in the excavation quarters. This study focuses upon multiple enacted receptions of historical spaces on the site, diachronically. Byzantine dwellers perceived and used the ancient site; the Museum creators integrated the Byzantine neighbourhood; contemporary visitors spontaneously signified the entire complex with new symbolic meaning.
The sulphur microbial diet (SMD), a dietary pattern associated with forty-three sulphur-metabolising bacteria, may influence gut microbiota composition and contribute to ageing process through gut-produced hydrogen sulfide (H2S). We aimed to explore the association between SMD and biological age (BA) acceleration, using the cross-sectional study that included 71 579 individuals from the UK Biobank. The SMD score was calculated by multiplying β-coefficients by corresponding serving sizes and summing them, based on dietary data collected using the Oxford WebQ, a 24-hour dietary assessment tool. BA was assessed using Klemerae–Doubal (KDM) and PhenoAge methods. The difference between BA and chronological age refers to the age acceleration (AgeAccel), termed ‘KDMAccel’ and ‘PhenoAgeAccel’. Generalised linear regression was performed. Mediation analyses were used to investigate underlying mediators including BMI and serum aspartate aminotransferase/alanine aminotransferase (AST/ALT) ratio. Following adjustment for multiple variables, a positive association was observed between consuming a dietary pattern with a higher SMD score and both KDMAccel (βQ4 v. Q1 = 0·35, 95 % CI = 0·27, 0·44, P < 0·001) and PhenoAgeAccel (βQ4 v. Q1 = 0·32, 95 % CI = 0·23, 0·41, P < 0·001). Each 1-SD increase in SMD score was positively associated with the acceleration of BA by 7·90 % for KDMAccel (P < 0·001) and 7·80 % for PhenoAgeAccel (P < 0·001). BMI and AST/ALT mediated the association. The stratified analysis revealed stronger accelerated ageing impacts in males and smokers. Our study indicated a higher SMD score is associated with elevated markers of biological ageing, supporting the potential utility of gut microbiota-targeted dietary interventions in attenuating the ageing process.
Instrumental tuition is by many seen as the cornerstone of higher music education (HME) performance programmes. An increasing body of research looks into its strengths and weaknesses and calls for development in a number of ways. This study contributes to this debate by exploring the ways in which international instrumental tuition practices are different, however limited to Western classical music practices. The article reports on a qualitative interview study of 12 students with experiences from 11 countries across America, Europe and Asia. Analysis of the interview data suggests that instrumental tuition practices are different when it comes to teacher positions, lesson formats and social organisation, responsibility and student voice and subject matter foci. These differences seem to correspond to social, musical and pedagogical structures and assumptions, and they could, as a result, be seen as differences on an international, institutional and individual level. The study suggests further that instrumental tuition practices could be seen as various manifestations of and negotiations between two broad archetypes in education: a teacher-centred archetype and a student-centred archetype. Increased knowledge about the variety of instrumental tuition practices is potentially a crucial matter in the field of HME, not the least due to power issues, and the study provides an analytical framework to analyse international, institutional and individual practices.
Although linked fate has been recognized as a driving force in the politics of various identity groups, should this theoretical framework be applied to queer politics? I ask, what are the outcomes and dynamics of linked fate among members of the queer community? How does linked fate shape queer political participation? Is the concept an adequate indicator of politicized queer identity? Drawing on data from the Collaborative Multiracial Post-Election Survey, I uncover widespread linked fate among queer Americans, with significant variation along the lines of intersectional identity. Linked fate can motivate participation, but more powerfully shapes participation beyond the ballot box. I close by calling for a queer-specific metric of linked fate that accounts for several dimensions of queer political identity. As the queer community grows increasingly salient in US party politics, this study identifies avenues for future research into this diverse population.
This work reports high-fidelity shock-tube experiments on the convergent Richtmyer–Meshkov (RM) instability at a heavy gas layer. The convergent shock tube is designed based on shock dynamics theory, significantly mitigating interface deceleration and reflected shock. As a result, long-term observation of instability growth up to nonlinear stage, free of interface deceleration and reshock, is achieved. Various types of SF$_6$ layers surrounded by air with controllable thicknesses and shapes, created using a soap film technique, are examined. For thick layers, the evolutions of the outer and inner interfaces are nearly decoupled regardless of the layer shape. The weakly nonlinear model of Wang (Phys. Plasmas,vol. 22, 2015, p. 082702), designed for cylindrical RM instability at a single interface, provides a reasonable prediction of perturbation growth at the inner interface, while slightly underestimating instability growth at the outer interface, as it neglects the effects of rarefaction wave. For thin layers, perturbation growth is fastest at either interface when both interfaces initially possess in-phase perturbations, moderate when only one interface is initially perturbed and slowest when the two interfaces have anti-phase perturbations. This variation in growth rates is due to the fact that the evolution of a thin layer is influenced by both reverberating waves and interface coupling, with each factor being highly sensitive to the layer shape. The original vortex method is extended to address the convergent RM instability by incorporating the influences of unsteady background flow, interface coupling and reverberating waves into the transport of a vortex sheet. This extended vortex method enables accurate prediction of convergent RM instability at a gas layer, covering the full range from early linear to late nonlinear stages.
The medieval Slavs approached Byzantine speculative thought with caution. This essay explores Slavic hesitancy towards Greek theoretical ambition within the writings on visions of the Bulgarian theologian Euthymios of Tarnovo. Whereas the Greek hesychast theologian Gregory Palamas argued that the saints behold God's glory without mediation, Euthymios took a more modest approach, asserting that angels arbitrate between heaven and earth and bestow visions on the saints. Earlier scholars have described Euthymios as a ‘hesychast’, yet his views on visions align more closely with Palamas’ opponents and the Corpus of Pseudo-Dionysios.