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Increasing electricity access remains a challenge, particularly in rural areas of sub-Saharan Africa. This study examines the case of Tanzania, where connection rates remain low even among rural households residing ‘under the grid’, and this despite substantial government subsidies for household connections. Using data from 1,774 rural households living within reach of the electricity grid, we investigate correlates of the low grid electricity uptake. We find that proxies for wealth are positively associated with connection status, while social network variables are less so. Capacity to pay thus appears to remain a major barrier, and in-house wiring costs emerge as a significant expense unaddressed by the existing subsidy scheme, exceeding grid connection costs sevenfold. Similar mechanisms influence the choice between grid electricity and traditional or solar energy sources. These findings inform the ongoing policy debate on subsidy design and the role of alternative energy sources in expanding access.
In his book Seeing Like a State, James Scott writes, “We have repeatedly observed the natural and social failures of thin, formulaic simplifications imposed through the agency of state power” (1998, 309). State and top-down planning lacks mētis, or the common sense and practical experience that people on the ground possess of their everyday environments. Instead, Scott proposes a focus on practical knowledge, which “depends on an exceptionally close and astute observation of the environment” (1998, 324).
Obesity, a global health issue, is associated with numerous diseases and has been shown to affect male reproductive health by inducing endocrine hormonal changes, chronic inflammation, oxidative stress and epigenetic alterations in reproductive cells. This study investigates the impact of obesity on testicular gene expression across mice, monkeys and humans, identifying 730 conserved testis-specific genes. High-fat diet-induced obesity upregulates GNG5, INHA, MSH5, SLC30A8 and SLC7A4 in testes, suggesting their potential as regulatory targets in testicular damage associated with obesity. Single-cell analysis reveals species-conserved expression patterns of SLC7A4 in Sertoli cells and SLC30A8 in SPG cells. It also confirmed that SLC30A8 and SLC7A4 were significantly upregulated in the testes of spontaneously obese mice. The findings highlight the potential of these genes as regulatory targets in obesity-related testicular dysfunction, providing insights into male reproductive health impairments caused by obesity.
The Cambrian edrioasteroid “Totiglobus” spencensis Wen et al., 2019 is redescribed on the basis of a new and exquisitely preserved specimen from the Cambrian Wuliuan of the Spence Shale Member, Langston Formation (Utah). This new occurrence is associated with soft-body preservation of several invertebrate groups and other shelly fossils. The description of “T.” spencensis was originally based on a single poorly preserved specimen. As a result, some of its features, such as curvature of the ambulacra and morphology of floor and cover plates, were misinterpreted or unavailable. The new material allows a new placement in Sprinkleoglobus spencensis n. comb. (Wen et al., 2019) on the basis of the general shape of the theca, attachment disc, and biserial flooring plates with podial pores and multiple cover plate series. The attachment disc of the new specimen lies in contact with a trilobite librigena, supporting evidence that this taxon is one of the earliest known examples of attachment to hard, mineralized substrata among Edrioasteroidea.
This study proposes two novel time-varying model-averaging methods for time-varying parameter regression models. When the number of predictors is small, we propose a novel time-varying complete subset-averaging (TVCSA) procedure, where the optimal time-varying subset size is obtained by minimizing the local leave-h-out cross-validation criterion. The TVCSA method is asymptotically optimal for achieving the lowest possible local mean squared error. When the number of predictors is relatively large, we propose a factor TVCSA method to reduce the computational burden by first reducing the dimension of predictors by extracting a few factors using principal component analysis and then obtaining the TVCSA forecasts from time-varying models with the generated factors. We show that the TVCSA estimator remains asymptotically optimal in the presence of generated factors. Monte Carlo simulation studies have provided favorable evidence for the TVCSA methods relative to the popular model-averaging methods in the literature. Empirical applications to equity premiums and inflation forecasting highlight the practical merits of the proposed methods.
A persistent problem that exists when considering minority groups – here conceived of as ethnic minorities – is the over-emphasis of an aspect of identity to represent the whole. In the west people of colour are seen through the lens of their colour and apparent racial difference. This is potentially limiting not only to their autonomy or right to shape their identity in their own terms but also within the therapeutic encounter. This article examines how misrepresentation of this kind occurs and what can be done to encourage a more empowering account of identity that advocates for the individual’s right to shape their identity and for the possibilities of a fuller perspective of identity that goes beyond racialised difference.
Parliaments are the intermediate link in the representative chain connecting citizens to the government. The parliamentary agenda is often seen as highly responsive because public priorities are usually mirrored in parliamentary debates. However, the level of responsiveness is affected by formal and informal rules of each activity, which considerably shape the attention–concentration capacity and thus the possibility for policy change. During moments of crisis, institutional frictions can be substantially placated, making the agenda concentrating on the crisis issue even in the presence of high institutional frictions. Building on the literature about parliamentary questioning and agenda-setting studies, this article compares the determinants of issue attention for crisis-related issues (economic, migration, and pandemic) in the Italian case over the past 20 years, assessing their impact on written questions and oral questions with immediate response. This article overcomes a limitation of the agenda-setting literature which treats different forms of parliamentary questions as having a single logic and dynamic. Instead, we demonstrate that frictions are extremely variable among different forms of parliamentary questioning and thus, that written and oral questions exhibit different forms of issue responsiveness. This article explores which type of signal parliamentary questions are most responsive to – public concerns, media attention, or real-world indicators – and finds that the answer is highly conditional both on the specific issue under examination and the type of parliamentary questions.
n-3 PUFA delivered by fish oil supplements alter the number and functions of circulating extracellular vesicles (EV), but consumption of oily fish does not reproduce this effect. In order to assess the effects of fish oil supplements and oily fish, at a level achievable in the diet, on EV numbers, composition and procoagulant activity in healthy human volunteers, forty-two healthy subjects were assigned to one of three treatment groups: (i) fish oil supplements plus white fish meals, (ii) control supplements plus oily fish meals or (iii) control supplements plus white fish meals for 12 weeks in a randomised, double-blind, placebo-controlled, parallel trial; circulating EV were enumerated and their procoagulant activity assessed using thrombin generation and fibrinolysis assays. Our results showed that fish oil supplements decreased circulating EV numbers and reduced EV-stimulated thrombin generation, but the consumption of oily fish at half the dose of EPA had no effect on either EV number or thrombogenic capacity. Consumption of both oily fish and fish oil supplements increased the EPA and DHA contents of EV, and the proportion of EPA in circulating EV was strongly associated with EV-stimulated thrombin generation. This study revealed that the additional 1 g/d EPA delivered in the fish oil supplements is required to decrease the numbers and thrombogenic capacity of EV, since oily fish at a level achievable in the diet had no effect. Increasing EPA intake beyond current guidelines for oily fish consumption may therefore be required for cardiovascular benefits relating to EV.
A reconfigurable leaky-wave antenna and its application capable of electronically steering the beam within the entire hemisphere is presented. The original antenna is designed as a 1D array of conducting patches on a dielectric substrate coupled by varactors in series with interdigital capacitors. The beam of this antenna is driven by a DC bias that controls the capacitances of the varactor diodes over a frequency range from 8 to 8.2 GHz. Simulations showed a change in the direction of the main radiation pattern within 55° at 8 GHz by varying the varactor capacitances in the range of 0.1 to 1 pF. The maximum gain is 10 dBi and the side lobe level is -10 dB. The fabricated antenna sample operates at an applied DC voltage between 0 and 12 V, which corresponds to varactor capacitances controlled in the range of 1 to 0.15 pF. This gives a range of elevation angles equal to 40°. The application of the antenna in a reconfigurable star-type structure is proposed. The direction of the main lobe of the radiation pattern in azimuth is controlled by switching between the centrally excited eight antenna arrays using PIN diodes. The direction of radiation in elevation is controlled by the DC bias of the varactors of a particular array switched to “ON”. This complex beam steering throughout the hemisphere represents a novel character of the presented antenna. The antenna has a planar structure. Low-cost printed circuit board technology was used for its fabrication.
Researchers explore the biology of painful experiences not primarily felt in the body (‘non-physical pain’), sometimes referred to as mental, social or emotional pain. A critical challenge lies in how to operationalise this subjective experience for biological research, a crucial process for translating findings into clinical practice.
Aims
To map studies investigating biological features of non-physical pain, focusing on their conceptual features (i.e. terms and definitions of non-physical pain) and methodological characteristics (e.g. experimental paradigms and measures).
Method
This methodological systematic review searched reports of primary research on the biological features of non-physical pain across Embase, MEDLINE and Web of Science. Using a meta-research approach, we synthetised results on terms, definitions, populations, experimental paradigms, confounders, measures of non-physical pain and investigation methods (e.g. functional magnetic resonance imaging).
Results
We identified 92 human studies, involving 7778 participants. Overall, 59.1% of the studies did not report any definition of non-physical pain, and 82% of studies did not use a specific measure. Regarding the possibility of translating results to clinical settings, most of the human studies involved only healthy participants (71.7%) and the seven different experimental paradigms used to induce non-physical pain had unknown external validity. Confounders were not considered by 32.4% of the experimental studies. Animal studies were rare, with only four rodent studies.
Conclusions
Biomedical studies of non-physical pain use heterogeneous concepts with unclear overlaps and methods with unknown external validity. As has been done for physical pain, priority actions include establishing an agreed definition and measurement of non-physical pain and developing experimental paradigms with good external validity.
Vanishing twin syndrome is a miscarriage of multiples where one or more fetuses ‘vanishes’ (i.e., partial or full resorption or via calcification) during pregnancy, often before detection via ultrasound. It affects 30−50% of multifetal pregnancies, with most cases resulting in full resorption within the first trimester. Despite its recognition since 1945 and rising occurrence in both natural and assisted pregnancies, standardized clinical guidelines remain inadequate, leading to inconsistent diagnosis, counseling, and communication from healthcare providers. This study examines the experiences of mothers and gestational carriers diagnosed with VTS, focusing on patient-provider communication, risks, and symptom disclosure. A global online survey collected qualitative and quantitative data from 153 participants across 17 countries. Results show that most patients with formal diagnoses experienced negative interactions with healthcare providers, with an average sentiment score of −0.7 (on a scale from −2 to 2). Over 53.4% rated their communication experience as −1, and the average satisfaction score for the amount of information received was 3.5/10. Additionally, 43% of respondents were not informed about chorionicity, a key factor affecting fetal outcomes. Significant discrepancies in care were observed across different countries. The findings highlight major gaps in patient-provider communication and inconsistent clinical practices regarding VTS. Addressing these issues through improved education, clearer protocols, and standardized guidelines could enhance patient experiences and decision-making. Future research should focus on provider training and evidence-based strategies to improve the management of VTS and other types of miscarriage and death of multiples during pregnancy and postpartum.
Scholars of gender have long realized that questions regarding gender, women, and politics require a multi-method, nuanced approach. When a plurality of white women voted for Donald Trump over Hillary Clinton in the 2016 presidential election, social scientists increasingly began to recognize the urgency of undertaking new approaches to understanding gender, race, and voting behavior in the United States.1 Since then, researchers have helped us understand why so many white women support right-wing candidates and policies that aim to suppress their autonomy, offering explanations such as the influence of belief in traditional gender roles (Christley 2022), “possessive investments in white heteropatriarchy” (Strolovitch, Wong, and Proctor 2017, 354), and “gendered nationalism” in American politics (Deckman and Cassese 2021, 278). In more recent years — as election results and polling suggest growing numbers of men of color have shifted rightward — there has been increased interest in employing an intersectional approach to analyze the gulf between men and women of color.
There has been substantial recent renewed interest and investment to assess the therapeutic potential of psychedelic compounds in addiction disorders. This editorial discusses the available evidence from randomised trials and future research directions in the field, together with potential implications for patients, professionals and the wider addiction treatment system.
This article examines the impact of informal intergovernmental relations on the Kenyan government’s handling of the COVID-19 pandemic. It argues that although informality in governance has been perceived negatively by many governance scholars, it nevertheless has the capacity to enhance the effectiveness and legitimacy of government. By virtue of informality’s adaptability and recognition of the centrality of context, it can enhance efficacy particularly in unpredictable circumstances as occurred in the pandemic. Notwithstanding this reality, until recently, literature on informality, mainly informed by Eurocentric colonial perspectives on governance, has focussed on its negative elements, criticizing it for diverse governance ailments. Through the prism of the negotiated order theory, this article challenges this dominant narrative using an analysis of informal intergovernmental relations during the COVID-19 pandemic in Kenya. It argues that though informality was at times applied negatively, overall, it ensured vibrant intergovernmental relations, thus positively impacting health service delivery and enhancing the government’s legitimacy in the management of the pandemic.
We show that dualising transfer maps in Hochschild cohomology of symmetric algebras over complete discrete valuations rings commutes with Tate duality. This is analogous to a similar result for Tate cohomology of symmetric algebras over fields. We interpret both results in the broader context of Calabi–Yau triangulated categories.