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This article reconstructs the student experience at St Mary’s College, Hammersmith (c.1854–1914), the first Catholic teacher training college in Britain. Using diaries, correspondence, magazines, and administrative records, it outlines the profile of the student body as predominantly young men of Irish descent from working-class communities in northern England and Scotland. It examines their educational formation, devotional practices, domestic routines, leisure pursuits, and the distinctive homosocial culture that bound them together as ‘Simmarians’. The article argues that St Mary’s was more than a site of professional preparation: it functioned as an ‘emotional community’ in which Catholic masculinity, vocation, and identity were consciously shaped. By situating the Simmarian experience within the wider development of Catholic schooling and the history of emotions, the study shifts attention from policy to lived formation, offering new insights into the making of Catholic teachers and the cultural significance of male community life in Victorian and Edwardian England.
This article explores how nation and nation-state materialize in interactional contexts and shape the social construction of gender in everyday life with a focus on Turkey. Judith Butler’s (2004) concept of “undoing gender” has influenced debates within the “doing gender” literature, a sociological body of work on the social construction of gender in everyday life, with particular attention to the deconstruction of heteronormativity. However, the more contestation of heteronormativity proliferated, the more the roles that the nation plays in the social construction of gender stayed obscured. I offer a corrective to nation-bound or nation-blind analyses of gender and propose the concept of the “heteronational matrix” as a perspective for analyzing how gender and sexualities are dynamically woven into the symbolic and material construction of the nation and nation-states, and how these constructions, in turn, shape the social construction of gender in everyday life.
This article examines the legitimacy of the Ashkenazi leadership via the meat hall in Amsterdam between 1673 and 1815, a central institution in a community marked by internal tensions from its inception. Drawing on archival sources and Suchman’s pragmatic, moral, and cognitive legitimacy (Suchman, “Managing Legitimacy”), it analyses how the meat hall functioned as a welfare mechanism and instrument of social control. The meat hall was faced with issues related to legitimacy from the beginning, evidenced by persistent meat smuggling, complaints about price and quality, and conflicts regarding supervision. This was exacerbated by high meat prices and limited welfare outcomes. The institution endured until the end of the 18th century because no viable alternative existed. When changing perceptions of religion, state, and citizenship rendered the monopoly increasingly unintelligible, it finally collapsed. The case illustrates how communal institutions can persist despite weak legitimacy until their underlying political order dissolves.
Failures of retraction are common in science. Why do they occur? And what determines whether a retraction is successful? We use data from citation records and Altmetrics to test proposed answers to these questions. LaCroix et al. (2021) employ network models to argue the social spread of information helps explain failures of retraction. One prediction is that widely known results, surprisingly, should be easier to retract, since their retraction is more relevant. Our results support this conclusion. We find highly cited papers show more significant reductions in citation after retraction and garner more attention to their retractions as they occur.
India’s Tele-MANAS (Tele Mental Health Assistance and Networking Across States) programme, launched in October 2022, is the world’s largest government-led tele-mental-health initiative. Operating via a multilingual 24/7 helpline, it provides stepped-care support, offering immediate counselling and escalating complex cases to psychiatrists or local services. In its first few years, Tele-MANAS has responded to more than 3.43 million calls across all Indian states and union territories. The majority of callers present with anxiety, depression or psychosocial stressors, while a critical minority report suicidal distress. Features such as linguistic inclusivity, anonymity and integration with India’s digital health ecosystem have driven rapid uptake, particularly among young adults. A World Health Organization (WHO) assessment has recognised Tele-MANAS as a scalable and equity-focused solution. The initiative illustrates how low- and middle-income countries can leverage technology and task sharing to reduce the treatment gap, offering a potential global blueprint for digital mental health care. This article aims to provide a programmatic overview of Tele-MANAS, including its design, early outcomes and key implementation challenges.
This article develops a theoretical framework of hybridization to reconceptualize norm diffusion in International Relations. Rather than treating norm diffusion as convergence towards a global standard and deviation as failure or resistance, it theorizes norm uptake as a process of normative recombination, theorizing hybridization as a structured, scope-condition-bound mode of norm evolution. The framework advances a typology of hybrid outcomes, ranging from dominant foreign influence to balanced hybridization to dominant local influence, and identifies key scope conditions explaining their variation, including economic dependency, institutional capacity, geopolitical hedging, and sector-specific dynamics. Empirically, the article applies this framework to a comparative analysis of Indonesia, Malaysia, and the Philippines, examining how these states engage China’s Digital Silk Road and mediate its embedded political–technological norms. The findings reveal that despite China’s significant infrastructural and economic presence, its normative influence remains so far limited. In particular, cybersecurity governance converges around Western-derived standards with minimal local adaptation, while ethical artificial intelligence governance reflects balanced hybridization shaped by domestic values and the Association of Southeast Asian Nations (ASEAN)-mediated multilateralism. Hybrid norms are thus not intermediate compromises between global and local models, but structured configurations shaped by institutional capacity, strategic positioning, and transnational contestation.
Dyslipidemia is associated with chronic low-grade inflammation and immune dysfunction, but the immunological effects of dietary phytosterols in humans remain unclear. We conducted a secondary analysis of an outcome-assessor-blinded, randomized controlled feeding trial to evaluate the effects of a high-phytosterol (HPS) diet, using phytosterol-enriched corn–wheat germ blended oil, compared with a low-phytosterol (LPS) diet using peanut oil, on systemic inflammatory markers, humoral immune markers and peripheral blood lymphocyte subsets in Chinese adults with dyslipidemia. After a 2-week run-in period, 104 participants were randomized to the HPS group (n=52) or the LPS group (n=52) for 12 weeks. In intention-to-treat analyses, the HPS group had a higher CD4+/CD8+ ratio at 12 weeks than the LPS group (adjusted mean difference: 0.561; 95 % CI: 0.060, 1.063; P = 0.03) and a lower CD8+ T-cell count (adjusted mean difference: -116.315 cells/μL; 95 % CI: -215.781,-16.849; P = 0.02). No significant between-group differences were observed for systemic inflammatory markers, humoral immune markers or most other lymphocyte subset outcomes. In per-protocol analyses, the difference in CD4+/CD8+ ratio remained significant, whereas the reduction in CD8+ T-cell count was attenuated. These exploratory findings suggest that a 12-week phytosterol-enriched corn–wheat germ blended oil intervention may be associated with changes in T-cell subset balance in adults with dyslipidemia, although the results should be interpreted cautiously given the exploratory nature of this secondary analysis.
Older adults in long-term care (LTC) homes experience complex nutrition-related challenges and care staff are central to supporting nutrition care, eating assistance, and positive mealtime experiences. However, nutrition care education is often inconsistently addressed in staff training. This scoping review mapped the scope, characteristics, and reported the outcome measures of nutrition care education and programs for LTC staff. This review followed JBI methodology and was reported according to PRISMA-ScR guidelines. Four databases (MEDLINE, CINAHL, Scopus, and PsycINFO) were searched from May to October 2024, with an updated search in September 2025. Grey literature and reference lists were also searched. Sixteen studies met the eligibility criteria. Programs varied in content, delivery format, duration, target staff groups, implementation supports, and outcomes. Common outcomes included staff knowledge, confidence, attitudes, eating assistance practices, mealtime environment, feasibility indicators, and selected resident nutrition outcomes. Future research should improve reporting, follow-up, outcome definitions, implementation, feasibility, and continuity.
In practical combustion systems, co-firing of ammonia (${\rm NH}_3$) with blends of methane (${\rm CH}_4$) and hydrogen (${\rm H}_2$) offers a promising pathway towards low-carbon combustion. However, the nonlinear thermoacoustic oscillations arising from such multi-fuel blends remain poorly understood, particularly in systems supporting intrinsic thermoacoustic (ITA) modes. In this study, we experimentally investigate the effects of varying fuel composition on thermoacoustic instability in a partially premixed swirl-stabilised combustor. Operating at a fixed thermal power ($k=4100\,\mathrm{W}$) and equivalence ratio ($\phi =0.85$), we systematically vary the fuel composition across blends of ${\rm CH}_4$, ${\rm H}_2$ and ${\rm NH}_3$, mapping the resulting dynamical transitions. We show that the system exhibits a sequence of nonlinear states depending on hydrogen enrichment: periodic limit-cycle for pure methane, quasiperiodicity at moderate ${\rm H}_2$ ($P_{\textrm{H}_2} = 0.2$–0.3) and period-3 state at higher enrichment ($P_{\textrm{H}_2} = 0.4$–0.5), all at fixed $P_{\textrm{NH}_3}$. As hydrogen content increases, the system undergoes mode-switching transitions within the ITA mode family, from high-frequency fourth-harmonic ($f_1$) to first-harmonic ($f_2$) oscillations, associated with strong pressure amplitudes and modified flame structures. Conversely, increasing ammonia content at constant $P_{\textrm{H}_2} \lt 0.3$ suppresses oscillation amplitudes across both periodic and quasiperiodic regimes. Our chemiluminescence imaging analysis reveals that the ITA-driven instabilities at its first harmonic ($f_2$) with shorter, flatter, M-shaped flames exhibit reduced flame response time and intensified heat release concentrated near the dump plane, leading to thermoacoustic amplification. These findings demonstrate that mode switching through precise tuning of $P_{\textrm{H}_2}$ and $P_{\textrm{NH}_3}$ offers new insights for the design of low-emission, fuel-flexible combustion systems.
We contribute to research addressing links between forest restoration and human well-being with an experimental study testing how exposure to a restored forest and birdsong impact mental stress, positive and negative experiences and perceived restorativeness. This study engaged 106 campus participants at North Carolina State University in a 2 × 2 experiment to assess the impacts of soundscapes (i.e., traffic noise versus birdsong) and a restored riparian forest (compared to proximate grey space). Soundscape and location were drivers of all well-being metrics (p < 0.001 for main effects in every case, with effect sizes ranging from η2 = 0.05 to 0.34). The restored forest with birdsong combination elicited the lowest stress, lowest negative experiences, highest positive experiences and highest perceived restorativeness (p < 0.05). The grey space with traffic noise combination was always the least beneficial (p < 0.05), and mixed treatments yielded intermediate results. These results build evidence that exposure to restored forest reduces stress, increases well-being and assists with perceived restorativeness; they also suggest that birdsong soundscapes have additive beneficial effects. These findings support the value of ecological restoration in urban areas, particularly when landscape restoration is accompanied by restoration of bird communities.
We analyse velocity spectra from direct numerical simulations (DNS) of turbulent pipe flow up to a friction Reynolds number $ \textit{Re}_{\tau } \approx 12{\,}000$. The spectral maps naturally partition into four regions, corresponding to small- and large-scale motions, and to wall-attached eddies, and are further divided into near-wall and outer contributions. Physically grounded models are formulated for each region, with particular emphasis on the near-wall range beneath the wall-attached eddies. Integration of the spectral models yields the distribution of the streamwise velocity variance in the lower part of the logarithmic layer, which agrees well with the DNS data. The analysis shows that the emergence of an outer-layer peak in the velocity variance at sufficiently high Reynolds number arises from the increasing relative contribution of wall-attached eddies, and can be interpreted without invoking additional physical mechanisms beyond this classical framework. Extrapolation to extremely high Reynolds numbers suggests a saturation of the velocity variance, characterised by two peaks of comparable magnitude.
AI provides a rich source of challenging examples for theories of agency because it allows relevant features to be relatively freely combined. This paper considers agency in sequence models: models that have been trained to predict the next item in a sequence. Training models on sequences of observations and actions can yield systems that use reinforcement learning in context, as well as ones that merely imitate agents. Investigating AI systems from this group suggests a requirement that agents must learn about the environment in part from their own interaction with it. It also suggests a distinction between two alternative approaches to understanding agency.
Antidepressants are the most frequently prescribed medications in psychiatry. Medical records of thousands of individuals provide a valuable opportunity to explore prescribing patterns and identify factors that influence treatment outcomes.
Aims
To investigate antidepressant change patterns in depression and non-depression indications and assess clinical and genetic factors associated with outcomes of antidepressant treatment.
Methods
Using primary care records from the UK Biobank, we examined outcomes including number of antidepressant changes and discontinuation due to either side-effects or inadequate response. Genetic analyses including heritability estimation, genetic correlation and polygenic score association were performed.
Results
A total of 82 633 individuals were prescribed at least 1 antidepressant. Of these, 28 332 individuals with at least 1 primary care depression diagnosis were classified as the depression group, and 24 543 individuals without evidence of depression were classified as the non-depression group. Citalopram and fluoxetine were the most prescribed antidepressants for depression, whereas amitriptyline dominated prescriptions for non-depression indications. Individuals with depression were more likely to stay on antidepressants longer than those without depression and to follow preferred antidepressants that changed over time. Antidepressant changes and discontinuation were associated with a range of psychiatric and somatic conditions, including recurrent depression (early discontinuation: odds ratio = 1.96; late discontinuation: odds ratio = 2.63) and anxiety (early discontinuation: odds ratio = 1.37; late discontinuation: odds ratio = 1.99) in the depression group, and pain-related conditions in the non-depression group. Genetic analyses identified two novel variants associated with early discontinuation of selective serotonin reuptake inhibitors. Notable genetic overlap was shown between these outcomes and multiple psychiatric and physical traits, including the number of antidepressant changes with anxiety and depression (rg = 0.81–0.83), and polygenic scores for depression and attention-deficit hyperactivity disorder showed significant predictive value with respect to treatment outcomes.
Conclusions
These findings characterise antidepressant change patterns in primary care records and highlight the potential value of integrating clinical and genetic data to better understand factors associated with treatment outcomes.
This paper examines three early Roman priesthoods, specifically, the Vestal virgins, the Salii, and the Flamines, through the lens of their visual and symbolic prerogatives, adopting a diachronic perspective based on literary sources, iconographic evidence, and archaeological data. The study highlights the deep historical roots of priestly paraphernalia in pre- and proto-historic funerary contexts, as well as a significant shift in gender dynamics. Prior to the 8th c. BCE, numerous male religious and martial figures are depicted with double shields and other distinctive attributes. From the 8th c. BCE to the Archaic period, both male and female religious figures appear, often equipped with knives, while double shields gradually disappear. This pattern suggests an expanding definition of religious and political prerogatives. By the 8th c. BCE, specialized male and female figures (identified by their knives) assume religious roles, whereas male warriors become kings (reges), holding political authority and often serving as Augurs as well.*
Ultra-processed food (UPF) consumption has generated a great deal of concern among nutrition scientists and consumers due to its potential relationship with increased risk of adverse health impacts. Evidence from intervention studies comparing UPF-rich and less-processed diets on cardiometabolic health outcomes is limited. Clinical trials that have been published to date focus on comparing more- and less-processed diets, as defined by the Nova system, and their impact on weight-related outcomes. Only one trial compares equally healthful more- and less-processed diets. The Dietary Guidelines for Americans with Ultra-Processed foods (DGA-UP) study will be the first trial to examine whether there is a differential effect to following recommendations from the 2020-2025 Dietary Guidelines for Americans (2020 DGA) including more- or less-processed foods as defined by the Nova classification system on cardiometabolic disease risk factors. A randomized controlled crossover dietary intervention study, DGA-UP will be conducted with 4 week provision of all meals to generally healthy male and female adults at eucaloric levels. The trial will consist of 2 dietary arms: 1) a less-processed 2020 DGA diet and 2) a ultra-processed 2020 DGA diet. The primary outcome is change in blood pressure on each diet from baseline to week 4. Both interventions will have excellent diet quality and contain similar amounts of macronutrients and micronutrients as well as the same types of food. DGA-UP will help to fill a significant research gap regarding potential impact of UPFs on cardiometabolic health markers independent of food type, diet quality, and micronutrient content. ClinicalTrials.gov registration: NCT07252037