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Flow field in the near wake of a short-finite circular cylinder at $L/D=1.0$ with an angle of attack between 0$^\circ$–15$^\circ$, where the transition from the non-reattaching flow to the reattaching flow appears, is investigated in wind tunnel tests with a supportless condition. Stereo particle image velocimetry measurements were applied to the experiments at the Reynolds number of $3.46\times 10^4$, and velocity fields in the near wake were obtained. The data was mainly analysed using spectral proper orthogonal decomposition. Characteristic large-scale wake structures of recirculation bubble pumping and large-scale vortex shedding were identified in the near wake of the cylinder regardless of the angle of attack. The phase difference of expansion and contraction of the recirculation flow appears in the recirculation bubble pumping at $\alpha \neq 0^\circ$. On the other hand, the eigenfunctions of velocity fluctuations at the vortex shedding frequency show a similar spatial pattern regardless of $\alpha$. Frequency analyses of wake position calculated from the reconstructed velocity field clarified that peak frequency is different between two in-plane directions when $\alpha \neq 0^\circ$. In addition, three vortex shedding patterns (anticlockwise/clockwise circular and flapping) are identified not only at $\alpha =0^\circ$ but also $\alpha \neq 0^\circ$. The feature of wake position in the radial direction for each pattern is observed regardless of the angle of attack. The relationship between the recirculation bubble pumping and the wake position in the radial direction is apparent in the non-reattaching flow but is weaker with $\alpha$ in the reattaching flow.
There is a lack of longitudinal data on the relationship between upward social comparison on social network sites (SNSs) and depression and its underlying mechanisms. Therefore, this study aimed to examine the relationship between upward social comparison on social network sites and depression and analyze the mediating effects of self-concept clarity and self-esteem in this relationship. We employed a two-wave longitudinal design among 1179 Chinese middle school students. The results indicated that : upward social comparison on SNSs predicted middle school students’ depression; Self-concept clarity and self-esteem sequentially mediated the relationship between upward social comparison on SNSs and middle school students’ subsequent depression. These results suggested that three types of interventions could be effectively used to decrease the risk of depression among middle school students.
In the present discussion, I will focus on the creation of baby warriors in Mesoamerica in a twofold manner: as human beings and as blade stones. The emphasis will be on central Mexico, complemented with essential data from other parts of Postclassic Mesoamerica. By juxtaposing information from historical sources in a novel way, this investigation seeks to offer new insights that should reinforce the idea that warriors captured on the battlefield were considered to be children. Although this idea has been suggested before, this article aims to contribute new historical evidence that not only confirms this notion but also widens our understanding of the creation of nonbiological offspring. Making kin out of Others aims to satisfy a cosmological need to incorporate vital energy and elements for individual and collective personhood from outside of the community. The second idea of this investigation focuses on a related productive variant of this gestational dynamic, suggesting that by stone flaking and chipping, children (of stone) were fabricated. Some of them were indeed “child blade stones” who personified warriors and fed themselves with sacrificial victims, securing sustenance for the hungry gods. I argue that the birth of these warriors should be integrated into a major mythological theme—namely, the Child Hero and the Old Adoptive Mother.
We study scaled topological entropy, scaled measure entropy, and scaled local entropy in the context of amenable group actions. In particular, a variational principle is established.
Hybrid procedure of hypoplastic left heart syndrome, comprising ductus arteriosus stenting and bilateral pulmonary artery banding, is a good surgical option for initial palliative procedure for high-risk patients for Norwood procedure. However, ductal stenting may cause retrograde aortic blood flow obstruction. Furthermore, complete removal of stent while performing the Norwood procedure make the operation more difficult. We report a case that overcame these problems using a novel surgical technique.
Pulmonary atresia with intact ventricular septum is a rare congenital cardiac lesion with significant anatomical heterogeneity. Surgical planning of borderline cases remains challenging and is primarily based on echocardiography. The aim was to identify echocardiographic parameters that correlate with surgical outcome and to develop a discriminatory calculator.
Methods:
Retrospective review of all pulmonary atresia with intact ventricular septum cases at a statewide tertiary paediatric cardiac centre was performed between 2004 and 2020. Demographic, clinical, and echocardiographic data were collected. Logistic regression was used to develop a discriminatory tool for prediction of biventricular repair.
Results:
Forty patients were included. Overall mortality was 27.5% (n = 11) and confined to patients managed as univentricular (11 vs 0, p = 0.027). Patients who underwent univentricular palliation were more likely to have an associated coronary artery abnormality (17 vs 3, p = 0.001). Fifteen surviving patients (51.7%) achieved biventricular circulation while 14 (48.3%) required one-and-a-half or univentricular palliation. Nineteen patients (47.5%) underwent percutaneous pulmonary valve perforation. No patients without tricuspid regurgitation achieved biventricular repair. The combination of tricuspid valve/mitral valve annulus dimension ratio and right ventricle/left ventricle length ratio identified biventricular management with a sensitivity of 93% and specificity of 96%. An online calculator has been made available.
Conclusion:
Pulmonary atresia with intact ventricular septum is a challenging condition with significant early and interstage morbidity and mortality risk. Patient outcomes were comparable to internationally reported data. Right ventricle/left ventricle length and tricuspid valve/mitral valve annulus dimension ratios identified a biventricular pathway with a high level of sensitivity and specificity. Absent tricuspid regurgitation was associated with a univentricular outcome.
Super-resolution of turbulence is a term used to describe the prediction of high-resolution snapshots of a flow from coarse-grained observations. This is typically accomplished with a deep neural network and training usually requires a dataset of high-resolution images. An approach is presented here in which robust super-resolution can be performed without access to high-resolution reference data, as might be expected in an experiment. The training procedure is similar to data assimilation, wherein the model learns to predict an initial condition that leads to accurate coarse-grained predictions at later times, while only being shown coarse-grained observations. Implementation of the approach requires the use of a fully differentiable flow solver in the training loop to allow for time-marching of predictions. A range of models are trained on data generated from forced, two-dimensional turbulence. The networks have reconstruction errors which are similar to those obtained with ‘standard’ super-resolution approaches using high-resolution data. Furthermore, the methods are comparable to the performance of standard data assimilation for state estimation on individual trajectories, outperforming these variational approaches at initial time and remaining robust when unrolled in time where performance of the standard data-assimilation algorithm improves.
Mitochondrial trifunctional protein deficiency is a long-chain fatty acid disorder that may include manifestations of severe cardiomyopathy and arrhythmias. The pathophysiology for the severe presentation is unclear but is an indicator for worse outcomes. Triheptanoin, a synthetic medium chain triglyceride, has been reported to reverse cardiomyopathy in some individuals, but there is limited literature in severe cases. We describe a neonatal onset of severe disease whose clinical course was not improved despite mechanical support and triheptanoin.
Early gut microbiome development may impact brain and behavioral development. Using a nonhuman primate model (Macaca mulatta), we investigated the association between social environments and the gut microbiome on infant neurodevelopment and cognitive function. Infant rhesus monkeys (n = 33) were either mother-peer-reared (MPR) or nursery-reared (NR). Neurodevelopmental outcomes, namely emotional responsivity, visual orientation, and motor maturity, were assessed with the Primate Neonatal Neurobehavioral Assessment (PNNA) at 14–30 days. Cognitive development was assessed through tasks evaluating infant reward association, cognitive flexibility, and impulsivity at 6–8 months. The fecal microbiome was quantified from rectal swabs via 16S rRNA sequencing. Factor analysis was used to identify “co-abundance factors” describing patterns of microbial composition. We used multiple linear regressions with AIC Model Selection and differential abundance analysis (MaAsLin2) to evaluate relationships between co-abundance factors, microbiome diversity, and neuro-/cognitive development outcomes. At 30 days of age, a gut microbiome co-abundance factor, or pattern, with high Prevotella and Lactobacillus (β = −0.88, p = 0.04, AIC Weight = 68%) and gut microbiome alpha diversity as measured by Shannon diversity (β = −1.33, p = 0.02, AIC Weight = 80%) were both negatively associated with infant emotional responsivity. At 30 days of age, being NR was also associated with lower emotional responsivity (Factor 1 model: β = −3.13, p < 0.01; Shannon diversity model: β = −3.77, p < 0.01). The infant gut microbiome, along with early-rearing environments, may shape domains of neuro-/cognitive development related to temperament.
Several metrics exist for matching the size of donor to recipient in paediatric cardiac transplantation. Different centres employ different metrics for size-matching to determine the viability of donor hearts. Inconsistent evidence exists, with limited consensus as to the metric for size-matching that is most predictive of outcomes after cardiac transplantation. Furthermore, any metric must function within the tight timeline available for the assessment of the suitability of the donor. At the time of the writing of this paper, the most commonly used metric for size-matching in paediatric cardiac transplantation is the donor-to-recipient body weight ratio. In this article, we review published literature evaluating commonly used metrics for size-matching in paediatric cardiac transplantation, including weight, height, body surface area, and imaging parameters.
We prove a functional version of the additive kinematic formula as an application of the Hadwiger theorem on convex functions together with a Kubota-type formula for mixed Monge–Ampère measures. As an application, we give a new explanation for the equivalence of the representations of functional intrinsic volumes as singular Hessian valuations and as integrals with respect to mixed Monge–Ampère measures. In addition, we obtain a new integral geometric formula for mixed area measures of convex bodies, where integration on $\operatorname {SO}(n-1)\times \operatorname {O}(1)$ is considered.
We establish bounds for exponential sums twisted by generalized Möbius functions and their convolutions. As an application, we prove asymptotic formulas for certain weighted chromatic partitions by using the Hardy–Littlewood circle method. Lastly, we provide an explicit formula relating the contributions from the major arcs with a sum over the zeros of the Riemann zeta-function.
Moral injury is the profound psychological distress that can arise from exposure to extreme events that violate an individual’s moral or ethical code; for example, participating in, witnessing, or being subjected to behaviours that harm, betray or fail to help others. Given that the experience of moral transgression is inherent to moral injury-related post-traumatic stress disorder (PTSD), it is important to consider patients’ religious beliefs and formulate how these may interact with their distress. In this article we describe how to adapt cognitive therapy for PTSD (CT-PTSD) to treat patients presenting with moral injury-related PTSD, who identify as religious. Anonymised case examples are presented to illustrate how to adapt CT-PTSD to integrate patient’s religious beliefs and address moral conflicts and transgressions. Practical and reflective considerations are also discussed, including how a therapist’s personal beliefs may interact with how they position themselves in the work.
Key learning aims
(1) To understand the importance of patients’ religious beliefs in the context of moral injury-related distress.
(2) To understand how patients’ religious beliefs can be integrated into Ehlers and Clark’s (2000) model when working with moral injury-related PTSD.
(3) To offer practical adaptations for CT-PTSD to integrate patients’ religious beliefs and practices, including how to set up a consultation with a religious expert in therapy.
(4) To aid therapist reflection on how their personal beliefs interact with how they position themselves in therapeutic work with religious patients.
Recently, convergence liberals, such as Kevin Vallier, argue that the principle of social insurance could be publicly justified. Our paper challenges this marriage of convergence liberalism and welfare state. We begin by examining Vallier’s three reasons for the principle of social insurance: risk aversion, injustice and the promotion of political trust. We then argue that all these reasons are intelligibly objectionable. After examining five possible responses that convergence liberals may offer, this paper concludes that the principle of social insurance is not conclusively justified in the convergence conception of public justification.
We establish the restricted sumset analog of the celebrated conjecture of Sárközy on additive decompositions of the set of nonzero squares over a finite field. More precisely, we show that if $q>13$ is an odd prime power, then the set of nonzero squares in $\mathbb {F}_q$ cannot be written as a restricted sumset $A \hat {+} A$, extending a result of Shkredov. More generally, we study restricted sumsets in multiplicative subgroups over finite fields as well as restricted sumsets in perfect powers (over integers) motivated by a question of Erdős and Moser. We also prove an analog of van Lint–MacWilliams’ conjecture for restricted sumsets, which appears to be the first analogue of Erdős--Ko–Rado theorem in a family of Cayley sum graphs.
The Nasrid emirate of southern Iberia emanated power through architecture; this project aims to better understand how this was made possible, via an interdisciplinary exploration of the Alhambra monument and other Al-Andalus constructions. Initial results of archaeological campaigns, structure chronologies and communication plans undertaken in 2021 and 2022 are presented.
We report a case of right ventricle to pulmonary artery conduit angioplasty in which a valvuloplasty balloon ruptured circumferentially and was retained within the conduit. A high-pressure balloon was used to relieve the obstruction and free the ruptured balloon. The procedure was further complicated when the distal part of the balloon broke away from the proximal part during an attempt to retrieve it back into the femoral sheath. This report highlights the inappropriate use of a soft balloon in a calcified xenograft conduit, which led to a series of complications, and discusses potential strategies for managing these complications.