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This paper proposes an innovative hybrid package integration strategy compatible with silicon-based technologies. It is evaluated beyond 200 GHz by the integration of a WR3 back-to-back waveguide-to-suspended stripline transition designed in BiCMOS technology, relying on metallic split-block package and organic laminate substrate. Simulated insertion loss below 3 dB is observed in the 220–320 GHz frequency band, competing with reported traditional solutions using III–V substrates. The achieved performances lead to promising perspectives for low-cost silicon packaging solutions beyond 200 GHz.
The change in brand from British Railways to British Rail (BR) marked an important moment in the history of Britain’s railway. Running alongside BR’s modernization was a wider process of “professionalization” within the field of marketing. This paper explores how the wider professionalization of marketing impacted BR’s own marketing practices, showing that after 1965 BR opened its doors to new methods, means, and perhaps most importantly, specialists from outside the railway industry. Such marketing efforts helped to frame the railway in terms of individual travelers’ specific economic needs: by 1968 it had effectively segmented its passengers into demographic audiences, and by 1975, BR had a much better understanding of its markets. These individual economies were often highly gendered and saw only mixed success, but ultimately demonstrated an application of research, advertising, and promotion.
We prove that the Center Conjecture passes to the Artin groups whose defining graphs are cones, if the conjecture holds for the Artin group defined on the set of the cone points. In particular, it holds for every Artin group whose defining graph has exactly one cone point.
Direct numerical simulations of spanwise-rotating turbulent channel flow with a parabolic bump on the bottom wall are employed to investigate the effects of rotation on flow separation. Four rotation rates, $Ro_b := 2\varOmega H/U_b = \pm 0.42$, $\pm$1.0, are compared with the non-rotating scenario. The mild adverse pressure gradient induced by the lee side of the bump allows for a variable pressure-induced separation. The separation region is reduced (increased) when the bump is on the anti-cyclonic (cyclonic) side of the channel, compared with the non-rotating separation. The total drag is reduced in all rotating cases. Through several mechanisms, rotation alters the onset of separation, reattachment and wake recovery. The mean momentum deficit is found to be the key. A physical interpretation of the ratio between the system rotation and mean shear vorticity, $S:=\varOmega /\varOmega _s$, provides the mechanisms regarding stability thresholds $S=-0.5$ and $-$1. The rotation effects are explained accordingly, with reference to the dynamics of several flow structures. For anti-cyclonic separation, particularly, the interaction between the Taylor–Görtler vortices and hairpin vortices of wall-bounded turbulence is proven to be responsible for the breakdown of the separating shear layer. A generalized argument is made regarding the essential role of near-wall deceleration and resultant ejection of enhanced hairpin vortices in destabilizing an anti-cyclonic flow. This mechanism is anticipated to have broad impacts on other applications in analogy to rotating shear flows, such as thermal convection and boundary layers over concave walls.
While much of the scholarship on gender and corruption suggests that women in political office are, or are perceived to be, less corrupt than men, in just the past few years corruption accusations against Brazil's Dilma Rousseff and South Korea's Park Geun-hye have made headlines and led to their impeachment. In this article, we argue women heads of government are actually more likely to be charged with corruption due to pervasive beliefs that women, by their very presence, corrupt public office. Using cross-national data, we first demonstrate that women executives are significantly more likely to be formally accused of corruption than their male counterparts. We then present case studies of Brazilian President Rousseff and Turkish Prime Minister Çiller to demonstrate the powerful role of gendered discourse in motivating suspicion and inflaming elite and public sentiment and thereby driving corruption charges. These findings make a substantial contribution to the literature on gender, leadership and the politics of corruption.
Temperature increase may cause some regions in the world to become marginal or unsuitable for Arabica coffee cultivation, due to either heat and/or marked water deficit. The feasibility of sustainable coffee production in these regions promotes good opportunity of income and value addition for rural producers within an expanding market. This study aimed to identify short-stature Arabica coffee cultivars with the best agronomic and qualitative performance in a low-altitude region. The experiment was located in northeastern São Paulo state, Brazil, at 565 m above sea level. During the experimental period (2014–2018) the average annual and November temperatures were 23.0 and 24.3°C, respectively, with an average annual water deficit of 109 mm. The experimental design was randomized blocks, with four replicates, and the treatments consisted of 17 short-stature cultivars. The cultivars Catuaí Amarelo IAC 62, Catuaí Vermelho IAC 99, IAC Ouro Amarelo, Obatã IAC 1669-20, Obatã IAC 4739, Tupi IAC 1699-33, IAC 125 RN and IPR 100 stood out in terms of yield, reaching approximately 50 bags/ha. The appropriate choice of Arabica coffee cultivar in a low-altitude region may result in yield increment of up to 74%. The cultivars Catuaí Vermelho IAC 99, Tupi IAC 1699-33 and IAC 125 RN produced grains with the best quality and highest hundred-grain weight, processing yield and percentage of grains retained on sieve 17. Therefore, it is possible for an Arabica coffee cultivar to have high yield and high grain and beverage quality in a low-altitude region, promoting production alternatives for farmers.
Cuneiform tablets indicate the importance of textile manufacturing in the Bronze Age Old Assyrian Colony Period and Hittite Empire, yet the organic traces of this industry rarely survive. Two burnt textile fragments found at Beycesultan offer an unexpected insight into the Bronze Age textile industry in Anatolia. Here, the authors present the results of chromatographic and microscopic analyses that indicate one fragment was made from hemp using the nålbinding, or single-needle knitting, technique and was dyed with the woad or indigo plant, while the other was a natural tabby weave. Both add to our understanding of the diversity of textile production in the Bronze Age.
We conduct direct numerical simulations (DNS) to study the temporal and spatial developments of the roll waves on a laminar sheet flow of Newtonian fluid. The DNS unveil the physics of the wavefront and show the limitation of the widely used shallow-layer approximations. The most prominent wave, the front runner, is determined by the DNS for the first time in studying the spatial development of the laminar sheet flow with negligible surface tension. Depending on the Froude and Reynolds numbers, the front runner can be a multi-peaked undular bore or a single-peaked non-breaking or breaking wave. The simulation has uncovered an extended region behind the wavefront, where the bed-friction stress is much higher than the corresponding friction in the undisturbed uniform flow. It also produces an uplift velocity needed in the description of wave breaking. For comparison, we also examine the nonlinear development of the instability using two-equation and four-equation shallow-layer models. The two-equation shallow-layer model has produced the bulk of the wave profile but is deficient because it fails to predict the uplift velocity and the substantial increase in bed friction in the frontal region. The four-equation shallow-layer model correctly predicts the bed friction but cannot produce the breaking wave. The simulations also determine the celerity and amplitude of the front runner to follow a linear relationship, qualitatively similar to the roll waves in a turbulent flow.
Cyprus, an island nation situated in the Eastern Mediterranean Sea, counts among the states that elected not to adopt the 2001 UNESCO Convention on the Protection of Underwater Cultural Heritage (henceforth: the 2001 UNESCO Convention), although recognizing its merits. With a coastline of 648 km, Cyprus’ seafloor holds an abundance of underwater cultural heritage. Despite that wealth, one searches in vain for a comprehensive study on the legal protection of its underwater cultural heritage. Instead, sporadic references to some of its provisions can be traced throughout the scholarly research surrounding the legal protection of underwater cultural heritage1 and maritime archaeology.2 Against this background, this article stands as the first thorough effort to reflect on Cyprus’ legal protection of its underwater cultural heritage.
Recent years have seen an increased focus on the implementation of Preferential Trade Agreements (PTAs). While the number of PTAs has risen remarkably since early 2000, data on the utilization of preferential tariffs under these agreements point out that some businesses have not gained access to all the benefits that PTAs can provide. When utilization rates are low, the impact of the agreement will likely differ from what was anticipated by ex-ante economic research. This paper conducts a dynamic Computable General Equilibrium (CGE) analysis of the expected impact of the EU–Japan Economic Partnership Agreement and compares a scenario that includes realistic preference utilization data with a standard scenario where all tariff liberalization is assumed to be fully utilized by businesses. The results show considerable differences between the two scenarios and illustrate the need to make the inclusion of credible utilization data standard practice in the modelling of international trade.
For $r\in(0,1)$, let $\mu \left( r\right) $ be the modulus of the plane Grötzsch ring $\mathbb{B}^2\setminus[0,r]$, where $\mathbb{B}^2$ is the unit disk. In this paper, we prove that
with $\theta _{n}\in \left( 0,1\right)$. Employing this series expansion, we obtain several absolutely monotonic and (logarithmically) completely monotonic functions involving $\mu \left( r\right) $, which yields some new results and extend certain known ones. Moreover, we give an affirmative answer to the conjecture proposed by Alzer and Richards in H. Alzer and K. Richards, On the modulus of the Grötzsch ring, J. Math. Anal. Appl. 432(1): (2015), 134–141, DOI 10.1016/j.jmaa.2015.06.057. As applications, several new sharp bounds and functional inequalities for $\mu \left( r\right) $ are established.
Uncaria rhynchophylla (Rubiaceae), a woody liana with significant medicinal value, has been used as a traditional Japanese and Chinese medicine. While effective seed production is required for breeding and efficient seedling production, the physiology of sexual reproduction remains largely unknown in this species. Therefore, we first observed the flowering behaviour, and next attempted artificial pollination using flowering individuals in a greenhouse. In this study it became clear that this species sets seeds by allogamy, but not by autogamy. The obtained seeds showed about a 90% germination rate. We also examined seed desiccation tolerance and storage conditions which are important to preserve the genetic resources. Seeds of this species were found to have a characteristic of the orthodox type, having high desiccation tolerance. Seeds after 6 months of storage at + 22, −20 and −160°C showed comparable germination rates to the seeds before storage.
Aortopulmonary window is a rare CHD, which comprises a communication between the ascending aorta and the pulmonary artery. The standard treatment of aortopulmonary window is surgical; however, few cases are amenable to closure via percutaneous intervention. We present a case of aortopulmonary window closure using Lifetech™ Konar-MF occluder device (Lifetech Scientific Co. Ltd., Shenzhen).
Warfarin is used as anticoagulation for children for a wide range of cardiac indications but carries the disadvantage of requiring international normalised ratio monitoring and dose adjustment. Management of warfarin therapy is challenging due to its narrow therapeutic window and is further complicated in children by dietary changes, frequent illnesses, and developing systems of metabolism and haemostasis.
A retrospective review was performed of patients’ medical records to assess the indication for warfarin use, percentage of international normalised ratio values in target range (%ITR), and frequency of phlebotomy.
Twenty-six patients were identified. The most common indication for warfarin use was in patients post-total cavo-pulmonary connection (n = 19, 73%). We demonstrated a variability in duration of warfarin therapy following total cavo-pulmonary connection (median of 11.1 months). Nineteen (73%) patients had used the CoaguChek machine for home measurement of international normalised ratio. The median frequency of phlebotomy for all indications was once every 10 days, and the median %ITR was 55.4 % (29.7–86.4%). Of note, the percentage under target range in the patients with mechanical mitral (n = 2) and aortic valves (n = 1) was found to be 23% and 33%, respectively.
These data demonstrate a high frequency of international normalised ratio values outside of the target range as seen in previous studies of warfarin in children. This necessitates frequent phlebotomy and dose changes, which can have a significant effect on the quality of life of these patients and their families highlighting the need to focus on quality improvement in the area of anticoagulation in paediatric cardiac patients.
Identifying persons with HIV (PWH) at increased risk for Alzheimer’s disease (AD) is complicated because memory deficits are common in HIV-associated neurocognitive disorders (HAND) and a defining feature of amnestic mild cognitive impairment (aMCI; a precursor to AD). Recognition memory deficits may be useful in differentiating these etiologies. Therefore, neuroimaging correlates of different memory deficits (i.e., recall, recognition) and their longitudinal trajectories in PWH were examined.
Design:
We examined 92 PWH from the CHARTER Program, ages 45–68, without severe comorbid conditions, who received baseline structural MRI and baseline and longitudinal neuropsychological testing. Linear and logistic regression examined neuroanatomical correlates (i.e., cortical thickness and volumes of regions associated with HAND and/or AD) of memory performance at baseline and multilevel modeling examined neuroanatomical correlates of memory decline (average follow-up = 6.5 years).
Results:
At baseline, thinner pars opercularis cortex was associated with impaired recognition (p = 0.012; p = 0.060 after correcting for multiple comparisons). Worse delayed recall was associated with thinner pars opercularis (p = 0.001) and thinner rostral middle frontal cortex (p = 0.006) cross sectionally even after correcting for multiple comparisons. Delayed recall and recognition were not associated with medial temporal lobe (MTL), basal ganglia, or other prefrontal structures. Recognition impairment was variable over time, and there was little decline in delayed recall. Baseline MTL and prefrontal structures were not associated with delayed recall.
Conclusions:
Episodic memory was associated with prefrontal structures, and MTL and prefrontal structures did not predict memory decline. There was relative stability in memory over time. Findings suggest that episodic memory is more related to frontal structures, rather than encroaching AD pathology, in middle-aged PWH. Additional research should clarify if recognition is useful clinically to differentiate aMCI and HAND.
The posterior pharyngeal wall is an anatomical subsite of both the oropharynx and hypopharynx. The treatment outcomes of squamous cell carcinoma (SCC) of these sites are generally published together, which makes the interpretation of data challenging. The aim of this analysis was to determine if there is any difference in the treatment outcomes of these two rare disease entities.
Materials and Methods
Retrospetive analysis showed that the posterior pharyngeal wall was the primary subsite in 17 patients (1.65 per cent) out of 1031 patients with oropharyngeal SCC, and in 23 patients (11.73 per cent) out of 196 patients with hypopharyngeal SCC.
Results
The five-year overall survival was 45 per cent for oropharyngeal origin and 53 per cent for hypopharyngeal origin patients. There was no significant difference in survival and locoregional control between these two groups of patients.
Conclusion
Squamous cell carcinoma of the posterior pharyngeal wall is a rare entity, which in our series represents 1.65 per cent of oropharyngeal cases and 11.73 per cent of hypopharyngeal tumours. There was no difference in treatment outcomes between the two groups.
In this paper, a high-order-mode (HOM) (TE330) cavity-fed 45° linear polarized 6×6 slot array antenna is proposed. The 45° linear polarization is achieved by introducing asymmetric cross slots on the HOM cavity, resulting in low profile and wide bandwidth. The antenna array was verified using standard printed circuit board technology. Measured results show that the impedance bandwidth ( $|S_{11}|\le$ −10 dB) is 13.9% (36.98–42.92 GHz), and the peak gain is 19.3 dBi with a 3-dB gain bandwidth of 13.6%. Attributed to its simple structure, low profile, and wide bandwidth, the presented antenna is a good candidate for 5G applications.
Ediacaran fossils, obtained in stratigraphic context in 1993, 1995, and 1996, with the assistance of A. Seilacher, IGCP project 320 scientists, and the Geological Survey of Namibia, are described for the first time. Most are from the Kliphoek and Buchholzbrunn members of the Dabis Formation and the Huns and Spitskop members of the Urusis Formation, Witputs subbasin, but a significant number, including Pteridinium, are from the Kliphoek Member, Zaris Formation, and the Neiderhagen Member, Nudaus Formation, north of the Osis arch, which separates the two subbasins. We extend the stratigraphic ranges and geographic distributions of several important taxa, including Archaeichnium, Ernietta, Pteridinium, and Swartpuntia, provide reassessments of the paleobiology of these and other organisms, and describe a new sponge—possibly an unmineralized archaeocyath—Arimasia germsi n. gen. n. sp. We also describe and illustrate various ichnofossils (including the oldest known traces from the Nama Group), narrow down the first appearance of Treptichnus in the Nama succession, and reinforce the idea that there was a prolific infauna of micrometazoans during the latest Ediacaran by naming and describing previously reported microburrows found on the surfaces of gutter casts as Ariichnus vagus n. igen. n. isp.