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We updated a descriptive analysis of national outpatient antibiotic prescribing during the COVID-19 pandemic. Prescribing volume was lower during 2020 and January–June in 2021 and 2022 compared to corresponding baseline months in 2019. Prescribing approached or exceeded baseline during July–December of 2021 and 2022 for all antibiotics, especially for azithromycin.
This chapter addresses the nexus between racism and return migration in the early 1980s, which marked the peak of anti-Turkish racism. As the call “Turks out!” (Türken raus!) grew louder, policymakers debated passing a law that would, in critics’ view, “kick out” the Turks and violate their human rights. During this “racial reckoning,” West Germans, Turkish migrants, and observers in Turkey grappled with the nature of racism itself. Although West Germans silenced the language of “race” (Rasse) and “racism” (Rassismus) after Hitler, there was an explosion of public discourse about those terms. Ordinary Germans, moreover, wrote to their president expressing their concerns about migration, revealing both biological and cultural racism. The simultaneous rise in Holocaust memory culture (Erinnerungskultur) is crucial for understanding this racial reckoning. While many Germans warned against the mistreatment of Turks as an unseemly continuity to Nazism, the emphasis on the singularity of the Holocaust offered Germans a way to dismiss anti-Turkish sentiment. Turkish migrants fought against this structural and everyday racism with various methods of activism. Turks at home, including the government and media following the 1980 military coup, viewed these debates with self-interest, lambasting German racism in the context of the 1983 remigration law.
The twenty-first century COVID-19 epidemic revealed a U.S. public health system that countenanced health inequities and a U.S. public that resisted disease containment policies. This crisis, however, was only the most recent chapter in a longer struggle in the United States to institutionalize public health. We focus on two early twentieth-century public health campaigns in the American South, the unhealthiest U.S. region at the time. Black southerners—denied basic health, political, economic, and social rights under a rising Jim Crow regime—self-organized health services networks, including through the Tuskegee Woman’s Club, the Negro Organization Society of Virginia, and the Moveable School (1890s–1915). Around the same time, a philanthropic project, the Rockefeller Sanitary Commission (RSC, 1909–1914), seeded state-level public health agencies in eleven southern states, thereby installing public health in a top-down manner. We use archival data sources to explore key similarities and differences in the public health concerns and coalition-building approaches of each campaign and southern resistance to their efforts. We find Black-led campaigns often blurred the color line to form coalitions that provided services to the underserved while tackling environmental health risks at the community level. In contrast, RSC affiliates in southern states, as directed by RSC administrators, provided health services as short-term public dispensaries. Services reached Black and White communities willing to participate but in a manner that did not overtly challenge Jim Crow-era practices. Southern resistance to public health expansion persisted under each approach. The legacies of these struggles remain; the political-economic and ideological forces that limited public health expansion while marginalizing Black community health efforts reverberate in public health inequities today.
This chapter sets out to identify key conceptual resources available for exploring power in the social construction of global environmental degradation for collective response. The chapter begins with the epistemic community model, which illuminates the role that transnational communities of scientists have in identifying issues like climate change and informing political action. This approach has been important for documenting the origins and establishment of the IPCC in 1988. However, empirical accounts informed by discursive and normative frameworks in other issue areas challenge the centrality of scientists in treaty formation. The studies reviewed identify the emergence of environmental issues as the source of new institutions; however, they also highlight how problem diagnosis has to converge with prevailing political and economic orders. Revisiting the IPCC’s emergence through the idiom of co-production at the end of the chapter, reveals how climate change had to be transformed into a global problem to fit with the existing remit of international organisation.
Operationalizing multi-site Community Engagement (CE) Studios to inform a research program is valuable for researchers. We describe the process and outcomes of hosting three CE Studios with Community Experts aged 65 years or older with chronic conditions and care partners of older adults. Experts gave feedback about processes for testing the feasibility, efficacy, effectiveness, and implementation of audio recording clinic visits and sharing recordings with patients who have multimorbidity and their care partners.
Methods:
The CE Cores of the Clinical and Translational Science Awards Programs at three academic health science centers created a joint CE Studio guide. Studios were conducted iteratively by site. Following receipt of the final reports, responses were compared to find themes, similarities, and differences on four topics in addition to overall commentary: Recruitment and Retention, Study Protocol, Study Reminders and Frequency, and Recording Technology.
Results:
Eighteen older adults and care partners in three states provided valuable feedback to inform multi-site trials. Feedback influenced multiple aspects of trials in process or subsequently funded. Experts provided critique on the wording of study invitations, information sheets, and reminders to engage in study procedures. Experts were concerned for participants being disappointed by randomization to a control arm and advised how investigators should prepare to address that.
Conclusions:
Multi-site CE Studios should be consecutive, so each team can learn from the previous teams. Using the CES Toolkit ensures that final reports were easily comparable and utilized to develop a research program that now includes three federally funded clinical trials.
Breast cancer is a major global health issue, especially among women. Previous research has indicated a possible association between psychiatric conditions, particularly schizophrenia, and an increased risk of breast cancer. However, the specific risk of breast cancer in women with schizophrenia, compared with those with other psychiatric disorders and the general population, remains controversial and needs further clarification.
Aims
To estimate the risk of breast cancer among people with schizophrenia compared with people with other psychiatric disorders and people in the general population.
Method
We utilised medical claims data of women aged 18 to 80 years in the Korean National Health Information Database from 2007 to 2018. Individuals with schizophrenia were defined as women with ICD-10 codes F20 or F25 (n = 224 612). The control groups were defined as women with other psychiatric disorders (n = 224 612) and women in the general Korean population (n = 449 224). Cases and controls were matched by index date and age, in a 1:1:2 ratio. We estimated the hazard of breast cancer using the Cox proportional hazards model, adjusting for insurance premiums and medical comorbidities. Among the people with schizophrenia, we used the landmark method to estimate the association between duration of antipsychotic medication use and the incidence of breast cancer.
Results
In multivariable Cox regression models, the hazard rate of breast cancer was 1.26 times higher in the people with schizophrenia than in the general population (95% CI: 1.20–1.32). In comparison with the psychiatric patient group, the hazard ratio was 1.17 (95% CI: 1.11–1.28). Among women with schizophrenia, the hazard of breast cancer was greater among those who took antipsychotic medications for 1 year or more compared with those who took antipsychotics for less than 6 months.
Conclusions
Women with schizophrenia have an elevated risk of breast cancer, and long-term use of antipsychotics is associated with an increased risk of breast cancer.
Contamination by heavy metals resulting from irrigation with wastewater is an important global concern, as it can lead to crop contamination, posing serious threats to human health. Despite the advances in bioremediation of soils, sustainable strategies that use beneficial microorganisms to reduce the accumulation of heavy metals in contaminated crops remain underexplored. The aim of this study was to evaluate the potential reduction of heavy metal concentration in different structures of bean plants cultivated in soils irrigated with untreated wastewater on an agricultural land located in Hidalgo, Mexico, through the inoculation of a ubiquitous soil fungus. Bean plants were inoculated with three Trichoderma spp. and distributed across eight treatments, with an additional untreated control group, following a random full design. The percentage of root colonization and concentration of heavy metals in the leaves, pods, grains, and soil were determined. The results revealed that root colonization exceeded 75%. The treatments T. harzianum + T. asperellum and T. harzianum with 3 × 106 spores ml−1 showed the greatest decrease in Cd (64.7%) and Pb (66.1%) concentrations in the grains. T. viride with 2 × 106 spores ml−1 was the most effective treatment for copper reduction (72.9%) in grains; T. harzianum with 3 × 106 spores ml−1 showed the best performance for chromium reduction (75.7%), which was below the detection limit in leaves. In conclusion, inoculation of bean plants with Trichoderma spp. effectively reduced the accumulation of heavy metals. Future research in this area could contribute to the development of sustainable strategies to mitigate heavy metal contamination in agricultural ecosystems, thereby promoting food and environmental safety.
Developing an appropriate context-based school-age obesity prevention programme, understanding the root causes of obesity in real-life situations is vital. The objectives of this study were to explore the risk factors of school-age obesity based on Ecological System Theory (EST) and develop mutual problem-solving guidelines for school-age obesity prevention.
Methods
Participation Action Research (PAR) was used as the study design. The data collection employed focus group discussions, in-depth interviews, participant’s observations, together with the procedures of Appreciation, Influence, and Control (AIC) with 55 school key informants.
Results
Risk factors supported by EST at all level included high-calorie intake; sedentary lifestyles; perceptions of ‘Chubby are cute’; indulgent parenting, including limited exercise area in school. PAR process guarantees the sustained context-based prevention guidelines.
Conclusions
The results could be used as a policy-driven for school-based participation and environmental support in order to promote health-promoting school.
Across the globe, people who mobilize to protect their rights in highly oppressive contexts may have to navigate government institutions that not only fail to implement protections but also engage in discriminatory practices. This article introduces the term “circumventive legal resistance” to describe practices of making legally grounded claims but facilitating relief through processes of expression and negotiation that are distinct from explicit mechanisms of legal enforcement. Based upon a study of twenty-seven rural, semi-rural, and urban areas across the north and north-west regions of India, this article documents how Dalit women—from the most marginalized groups at the base of the caste pyramid—mobilize to protect their rights in contexts where local institutions do not enforce laws prohibiting caste discrimination and instead perpetrate caste-based forced labor practices. In particular, I focus on a campaign to end manual scavenging—a form of caste-based forced labor that is one of the worst surviving symbols of untouchability. With local channels to legal relief largely foreclosed, Dalit women who leave manual scavenging engage in circumventive legal resistance: they draw on law to make claims but win relief through avenues distinct from those envisioned within the parameters of the law.
To evaluate the application of front-of-package (FOP) labelling regulations to menu labelling in the Canadian restaurant sector by assessing the proportion of menu items that would be required to display the ‘high-in’ FOP symbol if the policy were extended to the restaurant sector.
Design:
Nutrition information of 18 760 menu items was collected from 141 chain restaurants in Canada. Menu items were evaluated using the mandatory FOP labelling regulations promulgated in Canada Gazette II by Health Canada in July of 2022.
Setting:
Chain restaurants with ≥20 establishments in Canada.
Participants:
Canadian chain restaurant menu items including beverages, desserts, entrées, sides and starters.
Results:
Overall, 77 % of menu items in the Canadian restaurant sector would display a ‘high-in’ FOP symbol. Among these menu items, 43 % would display ‘high-in’ one nutrient, 54 % would display ‘high-in’ two and 3 % would display ‘high-in’ all three nutrients-of-concern. By nutrient, 52 % were ‘high-in’ sodium, and 24 and 47 % were ‘high-in’ total sugars and saturated fat, respectively.
Conclusions:
Given the poor nutritional quality of restaurant foods, the current regulations, if applied to restaurant foods, would result in most menu items displaying a FOP symbol. Therefore, expanding the Canadian FOP labelling regulations to the restaurant sector can be key to ensuring a healthy food environment for Canadians. Furthermore, menu labelling along with other multi-faceted approaches such as reformulation targets are necessary to improve the dietary intake of Canadians from restaurant foods.
Sergei Rachmaninoff is widely regarded as one of the great pianists of the twentieth century. In a research project that has stretched over two decades, I have compiled data on Rachmaninoff’s performance career, comprising research in archives as well as published sources in Russian and English languages. The resulting Rachmaninoff Performance Diary has been publicly available online since 2011. A missing link in the data has been the complete programmatic details of over 1,080 solo recitals. In 2006, I discovered research that was apparently unrecognized in its completeness in an archive of the Library of Congress, undertaken and donated by Rachmaninoff’s sister-in-law, Dr Sophia Satina. In this article, I examine the details of the 1924/25 season, which was a critical time for Rachmaninoff: after the collapse of his personal fortune caused by the Russian Revolution, he at last had achieved sufficient success and financial security from his hectic touring to allow him to return to composition the following year, his ‘sabbatical’ break of 1926. From the data, a clearer picture emerges of how Rachmaninoff varied his repertoire in his many concert appearances and recording sessions, showing how frequency of performance and, in instances, apparent self-assessment of his own music, were key factors.
First-of-a-kind engineered systems often burst with complexity – a major cause of project budget and time overruns. Our particular concern is the structural complexity of nuclear fusion devices, which is determined by the amount and entanglement of components. We seek to understand how this complexity rises during the development phase and how to manage it. This paper formulates a theory around the interplay between a problem-solving design process and an evolving design model. The design process introduces new elements that solve problems but also increase the quantifiable complexity of the model. Those elements may lead to new problems, extending the design process. We capture these causal effects in a hierarchy of problems and introduce two metrics of the impact of design decisions on complexity. By combining and incorporating the Function-Behavior-Structure (FBS) paradigm, we create a new problem-solving method. This method frames formulation, synthesis and analysis activities as transitions from problems to solutions. We demonstrate our method for a nuclear fusion measurement system. Exploring different design trajectories leads to alternative design models with varying degrees of complexity. Furthermore, we visualize the time-evolution of complexity during the design process. Analysis of individual design decisions emphasizes the high impact of early design decisions on the final system complexity.
We discuss the applicability of quasilinear-type approximations for a turbulent system with a large range of spatial and temporal scales. We consider a paradigm fluid system of rotating convection with vertical and horizontal temperature gradients. In particular, the interaction of rotation with the horizontal temperature gradient drives a ‘thermal wind’ shear flow whose strength is controlled by the horizontal temperature gradient. Varying this parameter therefore systematically alters the ordering of the shearing time scale, the convective time scale and the correlation time scale. We demonstrate that quasilinear-type approximations work well when the shearing time scale or the correlation time scale is sufficiently short. In all cases, the generalised quasilinear approximation systematically outperforms the quasilinear approximation. We discuss the consequences for statistical theories of turbulence interacting with mean gradients.
Migration destabilized family life, gender, and sexuality. Whereas most Turkish guest workers traveled alone during the formal recruitment period (1961–1973), West Germany’s subsequent policy of family reunification sparked the increased migration of spouses and children. This chapter shows that, although migrants developed strategies to maintain connections to home, separation anxieties and fears of abandonment loomed. The departure of able-bodied young workers strained local economies, upended gender roles, and separated loved ones, sparking tensions at home: were guest workers sending enough money home, communicating enough, and remaining faithful to spouses? In Germany, reports about sex between male guest workers and German women fueled Orientalist tropes about “foreigners,” perpetuated stereotypes about Turkish men’s propensity toward violence, and stoked fears about the transgression of national and racial borders. Women left behind worried that their husbands would commit adultery while abroad. Guest workers’ children were viewed simultaneously as victims and threats: some stayed behind in Turkey, others were brought to Germany, and thousands of “suitcase children” (Kofferkinder) repeatedly moved back and forth between the two countries with their bags perpetually packed. As physical estrangement evolved into emotional estrangement, the perceived abandonment of the family came to represent the abandonment of the nation.